|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Transformation of human amniotic epithelial cells into neuron-like cells in the microenvironment of traumatic brain injury in vivo and in vitro显示文摘Survival and differentiation of transplanted cells is closely related to the local microenvironment.The present study cultured human amniotic epithelial cells(HAECs) in a simulated microenvironment in vitro comprising RPMI 1640 culture medium and the solution extracted from injured brain tissues.Some HAECs were round,triangular in form or irregularly shaped,with extended neuron-like processes;some of the processes were interconnected,representing neuron-like morphology and some HAECs were microtubule-associated protein 2-positive.HAECs survived for at least 4 weeks following transplantation into the center and edges of the trauma focus with traumatic brain injury,and were microtubule-associated protein 2-positive.Moreover,the motor function of rat hind limbs was significantly improved. | Yi Lu Guozhen Hui Zhiyuan Wu Tianjin Liu Xunhe Ji Lihe Guo | 2011 | Neural Regeneration Research2011，6，10： | 10 |
| 2 | Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum显示文摘Human amniotic epithelial cells were isolated from a piece of fresh amnion. Using immunocytochemical methods, we investigated the expression of neuronal phenotypes (microtubule-associated protein-2, glial fibrillary acidic protein and nestin) in human amniotic epithelial cells. The conditioned medium of human amniotic epithelial cells promoted the growth and proliferation of rat glial cells cultured in vitro, and this effect was dose-dependent. Human amniotic epithelial cells were further transplanted into the corpus striatum of healthy adult rats and the grafted cells could integrate with the host and migrate 1-2 mm along the nerve fibers in corpus callosum. Our experimental findings indicate that human amniotic epithelial cells may be a new kind of seed cells for use in neurograft. | Zhiyuan Wu Guozhen Hui Yi Lu Tianjin Liu Qin Huang Lihe Guo | 2012 | Neural Regeneration Research2012，7，1： | 3 |
| 3 | Graph-regularized saliency detection with convex-hull-based center prior显示文摘 | Chuan Yang Lihe Zhang Huchuan Lu | 2013 | IEEE Sigal Processing Letters2013，20，7： | 1 |
| 4 | Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms显示文摘 | Zhiwei Xu Shiqing Lin Weikang Wu Hongmei Tan Zhi Wang Chao Cheng Lihe Lu Xuanhong Zhang | 2008 | Toxicology2008，，2： | 1 |
| 5 | Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure显示文摘 | LU LIHE WU WEIKANG YAN JIANYUN | 2009 | Int J Cardiol2009，134，1： | 1 |
| 6 | Adriamycin-indueed autophagie cardiomyocyte death plays A pathogenic roXe in a rat model of heart failure 显示文摘 | LU Lihe WU Weikang YAN Jianyun | 2009 | Int J Cardiol2009，134，1： | 1 |
| 7 | Adriamycin- induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure 显示文摘 | LIHE LU WEIKANG WU JIANYUN YAN | 2009 | International journal of cardiology2009，134，1： | 1 |
| 8 | Change Laws of Flake's Temperature during Making a Diamond Film by DC-PJ显示文摘Maldngdiamondfilmbydirectcurrentplasmajetisoneofhightechnologies.DevelopmenttrendofthetechnologyistOgetaIdleareafilmwithgoodqualitybyanequipmentwithhighpowerdirectcurrentplasmajetatPresent[l].However,duringthefilmgrowing,itsbasebodyhasvariabletempera... | Xuhong Chen Lihe Zhao Fanxiu Lu(Mechanical Engineering School, University of Science and Technology Beijing, Beijing 100083, China) | 1999 | International Journal of Minerals,Metallurgy and Materials1999，13，2： | 0 |
| 9 | Acetylcholinesterase is associated with apoptosis in β cells and contributes to insulin-dependent diabetes mellitus pathogenesis显示文摘Acetylcholinesterase (疼痛) 表示在 apoptosis 期间是枢轴的。确实,疼痛禁止者部分保护房间免受 apoptosis 的伤害。胰岛素依赖者糖尿病 mellitus (IDDM ) 被胰腺的房间 apoptosis 部分地描绘。这里,我们在 IDDM 的发展调查了疼痛的角色并且分析了疼痛禁止者的保护的效果。多重低剂量的 streptozotocin (MLD-STZ ) 管理在一个老鼠模型导致了 IDDM。西方的污点分析,细胞化学的染色,并且染色的 immunofluorescence 被用来在 MIN6 房间,主要房间,和 apoptotic 检测疼痛表示 MLD-STZ-treated 老鼠的胰腺的房间。疼痛禁止者予 MLD-STZ 老鼠 intraperitoneally 被以 30 天。血葡萄糖,血浆胰岛素,和肌酸层次被测量,并且葡萄糖忍耐测试被执行。MIN6 房间上的疼痛禁止者的效果也被评估。当与 STZ 对待时,疼痛表示在 vivo 在 vitro 和胰腺的小岛在 apoptotic MIN6 房间和主要房间被导致。正式就职和在胰腺的小岛的疼痛的进步累积在 IDDM 开发期间与 apoptotic 房间被联系。疼痛禁止者的管理有效地减少了在 MLD-STZ 老鼠的糖尿病的多糖症和发生,和恢复血浆胰岛素层次和血浆肌酸清理。疼痛禁止者部分保护了 MIN6 房间免受 STZ 治疗引起的损坏的伤害。在胰腺的小岛和 IDDM 的发作和发展上的疼痛禁止者的保护的效果的疼痛的正式就职和累积显示在疼痛和 IDDM 之间的一种靠近的关系。 | Bao Zhang Lei Yang Luyang Yu Bo Lin Yanan Hou Jun Wu Qin Huang Yifan Han Lihe Guo Qi Ouyang Bo Zhang Lu Lu Xuejun Zhang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员