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| 1 | Indocyanine green clearance test and model for end-stage liver disease score of patients with liver cirrhosis显示文摘BACKGROUND:The indocyanine green(ICG)clearance test(clearance rate(K)and retention rate at 15 minutes (R15))is a sensitive indicator to evaluate liver function. The model for end-stage liver disease(MELD)score has emerged as a useful tool for estimating the mortality of patients awaiting liver transplantation and has recently been validated on patients with liver diseases of various etiologies and severity.In this study,we investigated the correlation between the ICG clearance test and MELD score of patients with liver cirrhosis. METHODS:From June 2007 to March 2008,52 patients with liver cirrhosis admitted to our center were classified into Child-Pugh class A(8 patients),B(14)and C(30).The ICG clearance test(K value and R15)was performed by ICG pulse spectrophotometry(DDG-3300K),and the MELD scores of patients were calculated. RESULTS:As the Child-Pugh classification of liver function gradually deteriorated,the K value decreased, while R15 and MELD score increased.There were significant statistical differences in K value,R15 and MELD score in patients with different Child-Pugh classifications. Significant correlations were found between the parameters of the ICG clearance test(K value and R15)and MELD score.A negative correlation was observed between K value and MELD score(r=-0.892,P<0.05),while a positive correlation was observed between R15 and MELD score(r=0.804,P<0.05).CONCLUSIONS:The ICG clearance test and MELD score are good parameters for evaluating liver function.Moreover, K value and R15 have significant correlations with MELD score,especially the K value,which may be a convenient and appropriate indicator to evaluate liver function of patients with liver cirrhosis. | Sheng, Qin-Song Lang, Ren He, Qiang Yang, Yong-Jiu Zhao, De-Fang Chen, Da-Zhi | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，1： | 37 |
| 2 | Laparoscopic cystogastrostomy for the treatment of pancreatic pseudocysts: A case report显示文摘Pancreatic pseudocysts(PPs) are collections o pancreatic secretions that are lined by fibrous tissue and may contain necrotic debris or blood. The interventions including percutaneous, endoscopic o surgical approaches are based on the size, location symptoms and complications of a pseudocyst With the availability of advanced imaging system and cameras, better hemostatic equipments and excellent laparoscopic techniques, most pseudocyst can be found and managed by laparoscopy. We describe a case of a 30-year-old male patient with a pancreatic pseudocyst amenable to laparoscopi cystogastrostomy. An incision was made through the anterior gastric wall to expose the posterior gastri wall in close contact with the pseudocyst using an ultrasonically activated scalpel. Then, another incision was made for cystogastrostomy to obtain complete and unobstructed drainage. The patient recovered well after operation and was symptom-free during a 6-mo follow-up, suggesting that laparoscopi cystogastrostomy is a safe and effective alternative to open cystogastrostomy for minimally invasive management of PPs. | Qin-song Sheng Da-Zhi Chen Ren Lang Zhong-Kui Jin Dong-Dong Han Li-Xin Li Yong-Jiu Yang Ping Li Fei Pan Dong Zhang Zhao-Wei Qu Qiang He | 2008 | World Journal of Gastroenterology2008，14，30： | 15 |
| 3 | Establishment of an animal model of ischemic type intrahepatic biliary lesion in rabbits显示文摘AIM:To explore a method to establish an animal model of ischemic type intrahepatic biliary lesion in rabbits. METHODS:Forty Japanese white rabbits of clean grade were divided randomly into four groups(10 rabbits per group)including sham operation(SO) group,and artery-bile obstruction(ABO)-1 h group, ABO-2 h group and ABO-3 h group.All the rabbits in this study underwent the same initial surgical procedure in which the liver was prepared as for graft removal during liver transplantation.Subsequently in the SO group,no additional vascular intervention was performed,while in groups ABO-1 h,ABO-2 h and ABO-3 h,the animals underwent combined clamping of the hepatic artery and common bile duct with microvascular clips for 1,2 and 3 h,respectively.After the scheduled occlusion time,the clip was removed to recover blood supply.The animals were killed 4 wk after operation.The survival rate,liver function, cholangiography and histopathological manifestation of the rabbits in each group were observed. RESULTS:The survival rate was 100%in groups SO,ABO-1 h and ABO-2 h,while it was 60%in group ABO-3 h.At each observation time,the change degree of the indexes of liver function was proportional to the clamping time(ABO-3 h>ABO-2 h>ABO-1 h> SO,P<0.05).Cholangiographical and histopathologic manifestations both showed that intrahepatic biliary lesion aggravated proportionally with the increase of the clamping time. CONCLUSION:An animal model of ischemic type intrahepatic biliary lesion in rabbits is successfully established,which may provide a reliable technique for basic and clinical research into the etiology, development and prophylaxis of ischemic type intrahepatic biliary lesion after liver transplantation. | Qin-song Sheng Da-Zhi Chen Ren Lang Qiang He Yong-Jiu Yang Zhao-Wei Qu De-Fang Zhao Xiao-Sheng Zhang | 2009 | World Journal of Gastroenterology2009，15，6： | 9 |
| 4 | Autoimmune pancreatitis:report of two cases and literature review显示文摘BACKGROUND:Autoimmune pancreatitis(AIP)is a unique chronic inflammation of the pancreas in which autoimmune mechanisms are involved in the pathogenesis.It is characterized by clinical,histopathological,radiographic,serologic and therapeutic features.Since it was first described in 1995,increasing numbers of AIP patients have been diagnosed.METHODS:In this study,the data from 2 patients with AIP who had elevation of serum immunoglobulin G,positive autoantibody,swelling of the pancreas and narrowing of the main pancreatic duct on imaging were analyzed retrospectively.RESULTS:With the initial diagnosis of AIP,both patients underwent regular prednisone therapy,which was initiated at a dose of 40 mg per day with a tapering schedule of 5 mg every 2 weeks.The patients responded very well to treatment with prednisone.CONCLUSIONS:AIP is a relatively new disease entity.Although it is diagnosed by distinct characteristics of the clinical,radiologic,histopathologic,and serologic findings,many questions require further clarification,including its relationship to other autoimmune diseases and misdiagnosis as pancreaticobiliary malignancies. | Sheng, Qin-Song Chen, Da-Zhi Lang, Ren He, Qiang Han, Dong-Dong Pan, Fei Li, Ping Qu, Zhao-Wei | 2009 | Hepatobiliary & Pancreatic Diseases International2009，8，6： | 8 |
| 5 | In-situ cosmogenic ^(36)Cl denudation rates of carbonates in Guizhou karst area显示文摘This study quantifies surface denudation of carbonate rocks by the first application of in-situ cosmogenic36Cl in China. Concentrations of natural Cl and in-situ cosmogenic36Cl in bare carbonates from Guizhou karst areas were measured with isotope dilution by accelerator mass spectrometer. The Cl concentration varied from 16 to 206 ppm. The 36Cl concentrations were in range of (0.8-2.4)106 atom g-1 , resulting in total denudation rates of 20-50 mm ka-1 that averaged over a 104-105 a timescale. The 36Cl-denudation rates showed roughly a negative correlation with the local mean temperature. This preliminary observation may suggest the variations of proportions of chemical weathering and physical erosion in denudation process, depending upon local climatic conditions. | XU Sheng LIU CongQiang FREEMAN Stewart LANG YunChao SCHNABEL Christoph TU ChengLong WILCKEN Klaus ZHAO ZhiQi | 2013 | Chinese Science Bulletin2013，58，20： | 7 |
| 6 | Giant hepatobiliary cystadenoma in a male with obvious convex papillate显示文摘Hepatobiliary cystadenoma is an uncommon lesion that is most often found in middle-aged women and difficult to diagnose preoperatively.Here,we report a case of giant hepatobiliary cystadenoma in a male patient with obvious convex papillate.On the basis of imaging examinations,the patient was diagnosed as hepatobiliary cystadenoma prior to operation. Left hepatectomy was performed and the patient was symptom-free during a 6-mo follow-up period, suggesting that imaging examination is the major diagnostic method of hepatobiliary cystadenoma,and operation is its best treatment modality. | Zhao-Wei Qu Qiang He Ren Lang Fei Pan Zhong-Kui Jin Qin-Song Sheng Dong Zhang Xiao-Sheng Zhang Da-Zhi Chen | 2009 | World Journal of Gastroenterology2009，15，15： | 6 |
| 7 | Preventive effects of autologous bone marrow mononuclear cell implantation on intrahepatic ischemic-type biliary lesion in rabbits显示文摘BACKGROUND:The ischemic-type biliary lesion(ITBL)is one of the most serious biliary complications of liver transplantation. This study aimed to investigate the effects of autologous bone marrow mononuclear cell(BM-MNC)implantation on neovascularization and the prevention of intrahepatic ITBL in a rabbit model. METHODS:The rabbits were divided into control,experimental model,and cell implantation groups,with 10 in each group. The model of intrahepatic ITBL was established by clamping the hepatic artery and common bile duct.Autologous BM-MNCs were isolated from the tibial plateau by density gradient centrifugation and were implanted through the common hepatic artery.Changes in such biochemical markers as aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase,gamma-glutamyltranspeptidase,total bilirubin and direct bilirubin were measured.Four weeks after operation, cholangiography,histopathological manifestations,differentiation of BM-MNCs,microvessel density and the expression of vascular endothelial growth factor were assessed. RESULTS:Compared with the experimental model group, the BM-MNC implantation group showed superiority in the time to recover normal biochemistry.The microvessel density and vascular endothelial growth factor expression of the implantation group were significantly higher than those of the control and experimental model groups.The ITBL in the experimental model group was more severe than that in the implantation group and fewer new capillary blood vessels occurred around it.CONCLUSIONS:Implanted autologous BM-MNCs can differentiate into vascular endothelial cells,promote neovascu-larization and improve the blood supply to the ischemic bile duct,and this provides a new way to diminish or prevent intrahepatic ITBL after liver transplantation. | Qu, Zhao-Wei Chen, Da-Zhi Sheng, Qin-Song Lang, Ren He, Qiang Wang, Ming-Feng | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，6： | 4 |
| 8 | 需谨慎考虑符合出院标准的2019冠状病毒病患者的传染性显示文摘目前全球新型冠状病毒流行形势仍严峻且持续恶化。评估符合出院标准的2019冠状病毒病(COVID-19)患者的传染性对于疾病控制至关重要。本研究报告两例核酸检测结果与临床表现及影像学表现不相符的患者,以此来呼吁临床工作者谨慎考虑符合出院标准的COVID-19患者的传染性。 | Jun-wei SU Wen-rui WU Guan-jing LANG Hong ZHAO Ji-fang SHENG | 2020 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2020，21，5： | 2 |
| 9 | Laparoscopic cystogastrostomy for the treatment of pancreatic pseudocysts:a case report显示文摘 | Sheng QS Chen DZ Lang R | | 0，，： | 1 |
| 10 | Radiocarbon dating and Moessbauer spectroscopic study of the Mukaiyama landslide, Japan显示文摘 | Xu Sheng Zheng Guodong Lang Yuhua | 2003 | J Radioanalyt Nuclear Chem2003，258，2： | 1 |
| 11 | Epoxy-POSS/silicone rubber nanocomposites with excellent thermal stability and radiation resistance显示文摘Due to the rigid Si-O-Si backbone,silicone rubber(SR)have a widespread application in extreme environment such as high temperature and high-level radiation.However,the radiation stability of SR still does not meet the practical needs in special radiation environments.Herein we prepared epoxy POSS(e POSS)/SR nanocomposites with excellent thermal stability and radiation resistance.As a physical crosslinking point in the SR,addition of small amount of ePOSS not only enhanced the mechanical properties of the matrix,but also improved its thermal stability greatly due to their good compatibility.e POSS/SR had higher radiation stability in air than SR owing to the inhibition of radiation oxidation by ePOSS,and the yield of main gaseous radiolysis products(CH_(4),H_(2),CO and CO_(2))of SR and ePOSS/SR nanocomposites was determined.By analyzing the changes of chemical structure,thermal properties and mechanical properties of the ePOSS/SR nanocomposite,combined with the characteristics of gas products afterγ-irradiation,the radiation induced crosslinking and degradation mechanism of the nanocomposites was proposed comprehensively. | Mengni Shi Yinyong Ao Lei Yu Lang Sheng Shuangxiao Li Jing Peng Hongbing Chen Wei Huang Jiuqiang Li Maolin Zhai | 2022 | Chinese Chemical Letters2022，33，7： | 1 |
| 12 | Mediate effect of technology innovation capabilities investment capability and firm performance in Vietnam显示文摘 | Tseng Ming Lang Sheng Hsiang Lin Truong Nguyen Tuong Vy | 2012 | Procedia - Social and Behavioral Sciences2012，，： | 1 |
| 13 | Intra-document Coreference Resolution: The state of the art显示文摘 | Jun Lang Bing Qin Ting Liu Sheng Li | 2007 | Journal of Chinese Language and Computing2007，17，4： | 1 |
| 14 | Analysis of N′-nitrosonornicotine and its metabolites in rabbit blood with liquid chromatography/tandem mass spectrometric method显示文摘 | Beibei Zhao Sheng Wang Juan Wang Hailei Lang Shihao Sun Jian Mao Jianxun Zhang | 2012 | Journal of Chromatography B2012，，： | 1 |
| 15 | MiR-18a regulates expression of the pancreatic transcription factor Ptf1a in pancreatic progenitor and acinar cells显示文摘 | Yankun Yang Lei Ding Yang An Zhen-wu Zhang Yanhe Lang Sheng Tai Fangqi Guo Chun-Bo Teng | 2012 | FEBS Letters2012，，4： | 1 |
| 16 | Variation of iron species in sliding mud显示文摘Results of Mossbauer spectroscopy and ICP-AES measurement revealed a special distribution pattern of iron species in four crossing profiles of the Tertiary Formation Type of Landslides in Japan. In comparison with host rocks, the sliding mud in the landslide slip zone contains the higher ferrous iron content and/or trace pyrite, which indicates that the forming environment was relatively reducing. The total iron content also increased with an increase in ferric iron and pyrite, in contrast, decreased with an increase in ferrous iron content. The deep-gray and black mud layers formed and accumulated in various volumes within landslide slip zones are treated as the basic criteria for the slipping activity, because the soft mud saturated with groundwater is easy to create a plastic deformation. | Guodong Zheng Sheng Xu Yuhua Lang Zifang Meng | 2002 | Chinese Science Bulletin2002，47，23： | 1 |
| 17 | Methane oxybromination over Rh-based catalysts:Effect of supports显示文摘Bromine mediation has been regarded as one of the most efficient ways to activate and convert methane to useful organics.This article reports the effects of active components(Rh,Ru,Pd and Pt)and supports(SiO2,Mg O and Al2O3)on the catalysis of methane oxybromination.Among the prepared catalysts,Rh/SiO2 is the best in performance(CH4 conversion of ca.20%and CH3Br selectivity exceeding 70%).The results reveal that support type has a notable influence on the catalytic performance of Rh,especially on product distribution.The high selectivity to CH3 Br over Rh/SiO2 is attributed to its low propensity for CH3Br oxidation.It was found that Rh small in particle size shows high catalytic activity and CH3Br selectivity.Although silicalite-1 zeolite suffers from a certain degree of structural damage due to the presence of high temperature steam,the use of silicalite-1 as support results in a performance comparable to that of Rh/SiO2. | Peng Wang Lang Chen Sheng Shen Chak-Tong Au Shuangfeng Yin | 2020 | Chinese Journal of Chemical Engineering2020，28，7： | 1 |
| 18 | CD8 ~ T cells that produce interleukin - 17 regulate myeloid - derived suppressor cells and are associated with survival time of patients with gastric cancer 显示文摘 | Yuan Zhuang Liu sheng Peng Yong lang Zhao ct al | 2012 | Gastroenterology2012，143，4： | 1 |
| 19 | The Mediate effect of techonology innovation capabilities on investment capability and firm performance in Vietnam 显示文摘 | MING LANG TSENG SHENG HSIANG LIN TRUONG NGUYEN TUONG VY | 2012 | So- cial and Behavioral Sciences2012，，40： | 1 |
| 20 | Extending aromatic acids on TiO_(2)for cooperative photocatalysis with triethylamine:Violet light-induced selective aerobic oxidation of sulfides显示文摘Designing visible light photocatalysts with a metal oxide semiconductor as the starting material could expand a new horizon for the conversion and storage of solar energy.Here,the benchmark photocatalyst TiO_(2) was used to pursue this goal by anchoring aromatic acids.Extending the aromatic acid was strategically deployed to design TiO_(2) complexes with violet light-induced selective aerobic oxidation of sulfide as the probe reaction.With benzoic acid(BA)as the initial molecule,horizontally extending one or two benzene rings furnishes 2-naphthoic acid(2-NA)and 2-anthracene acid(2-AA).Moreover,triethylamine(TEA),an electron transfer mediator,was introduced to maintain the integrity of the anchored aromatic acids.Notably,there was a direct correlation between theπ-conjugation of aromatic acid ligand and the selective aerobic oxidation of sulfides.Among the three aromatic acids,2-AA delivered the best result over TiO_(2) due to the most extensiveπ-conjugated system.Ultimately,violet light-induced selective aerobic oxidation of sulfides into corresponding sulfoxides was conveniently realized by cooperative photocatalysis of 2-AA-TiO_(2) with 10 mol%of TEA.This work affords an extending strategy for designing the next-generation ligands for semiconductors to expand visible light-induced selective reactions. | Hui Li Xia Li Jun Zhou Wenlong Sheng Xianjun Lang | 2022 | Chinese Chemical Letters2022，33，8： | 0 |
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