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| 1 | A case-control study about the association between vascular endothelial growth inhibitor gene polymorphisms and breast cancer risk in female patients in Northeast China显示文摘Objective: The inhibition of the neovascularization in tumors is a potential therapeutic target of cancer. Vascular endothelial growth inhibitor(VEGI) is a member of the TNF superfamily which has the ability to suppress the formation of new vessels in tumors. In order to study the association between VEGI gene polymorphisms and breast cancer risk, a case-control study was conducted in Chinese Han women in Northeast China.Methods: Our study involved 708 female breast cancer patients and 685 healthy volunteers. Four SNPs of VEGI gene were analyzed through the polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) method. The association between VEGI gene polymorphisms and breast cancer risk was analyzed in our study. The relation between VEGI gene variants and clinical features of breast cancer including lymph node(LN) metastasis, estrogen receptor(ER), progestrogen receptor(PR), tumor protein 53(p53), human epidermal growth factor receptor 2(Her-2) and triple negative(ER-/PR-/Her-2-) status was analyzed as well.Results: We found that the CT genotype and T allele of rs6478106 were more frequent in patients than in controls. There was also a statistical difference in the distribution of C_(rs6478106)G_(rs4263839) haplotype between patients and controls. In addition, SNP rs6478106 and rs4979462 were related with the Her-2 status.Conclusions: Our results suggest that VEGI gene variants may be related to the breast cancer risk and the clinical features of breast cancer in Chinese Han women in Northeast China. | Shaoli Han Lei Liu Fengyan Xu Shuang Chen Weiguang Yuan Zhenkun Fu Dalin Li Dianjun Li | 2016 | Chinese Journal of Cancer Research2016，28，4： | 7 |
| 2 | Optical Image Encryption Based on Mixed Chaotic Maps and Single-Shot Digital Holography显示文摘Random phase masks play a key role in optical image encryption schemes based on double random phase technique. In this paper, a mixed chaotic method is proposed, which can efficiently solve some weaknesses that one-dimensional(1-D) single chaotic maps encounter to generate random phase masks. Based on the chaotic random phase masks, optical image encryption and decryption are realized with a single-shot digital holographic technique. In the proposed encryption scheme, the initial value and parameters of mixed chaotic maps serve as secret keys,which is convenient for the key management and transmission. Moreover, it also possesses high resistance against statistical attack, brute-force attack, noise attack and shear attack. Simulation results and security analysis verify the validity and security of the proposed encryption scheme. | Yonggang Su Chen Tang Xia Chen Biyuan Li Wenjun Xu Zhenkun Lei | 2017 | Transactions of Tianjin University2017，23，2： | 3 |
| 3 | To move or stay?A cellular automata model to predict urban growth in coastal regions amidst rising sea levels显示文摘Low-lying coastal cities are widely acknowledged as the most densely populated places of urban settlement;they are also more vulnerable to risks resulting from intensive land use and land cover change,human activities,global climate change,and the rising sea levels.This study aims to predict how urban growth is affected by sea level rise(SLR)in the Australian context.We develop an urban cellular automata model incorporating urban planning policies as potential drivers or constraints of urban growth under different SLR scenarios and adaption strategies.Drawing on data capturing the socioeconomic and environmental factors in South East Queensland,Australia,our model is positioned to address one core research question:how does SLR affect future urban growth and human resettlement?Results show that urban growth in coastal regions varies depending on the extent to which the sea level rises and is affected by a combination of factors relating to urban planning and human adaptation strategies.Our study demonstrates the complexity of urban growth in coastal regions and the nuanced outcomes under different adaptation strategies in the context of rising sea levels. | Siqin Wang Yan Liu Yongjiu Feng Zhenkun Lei | 2021 | International Journal of Digital Earth2021，14，9： | 2 |
| 4 | Stress transfer in microdroplet tensile test: PVC - coated and uncoated Kevlar - 29 single fiber显示文摘 | LEI Zhenkun WANG Quan KANG Yilan | 2010 | Optics and Lasers in Engineering2010，，48： | 1 |
| 5 | Experimental investigation of interfacial fracture behavior in foam core sandwich beams with visco-elastic adhesive inteface显示文摘 | Wang Can Chen Haoran Lei Zhenkun | 2010 | Composite Structures2010，92，5： | 1 |
| 6 | Experimentalinvestigation of interfacial fracture behavior in foam coresandwich beams with visco-elastic adhesive interface显示文摘 | Wang Can Chen Haoran Lei Zhenkun | 2010 | Composite Structures2010，92，5： | 1 |
| 7 | Whole-field determination of isoelinic parameter by five-step color phaseshifting and its error analysis显示文摘 | Lei ZhenKun Yun Dazhen Yu Wanming | 2003 | Optics and Lasers in Engineering2003，40，： | 1 |
| 8 | Study of shear transfer in A1/epoxy joint by digital photoelasticity显示文摘 | Lei Zhenkun Yun Hai Zhao Yanru | 2009 | Optics and Lasers in Engineering2009，47，6： | 1 |
| 9 | Experimental investigation of interracial fracture behavior in foam core sandwich beams with visco-elastic adhesive interface 显示文摘 | Wang Can Chen Haoran Lei Zhenkun | 2010 | Composite Structures2010，92，： | 1 |
| 10 | An application of Raman spectroscopy on the measurement ofresidual stress in porous silicon显示文摘 | KANG Yilan QIU Yu LEI Zhenkun | 2005 | Optics and Lasers in Engineering2005，43，8： | 1 |
| 11 | Micromechanics analysis of Kevlar-29 aramid fiber and epoxy resin micro- droplet composite by Micro-Raman spectroscopy显示文摘 | Hao Cen Yilan Kang Zhenkun Lei | 2006 | Com- posite Structures2006，75，1： | 1 |
| 12 | Stress transfer in microdroplet tensile test: PVC-coated and uncoated Kevlar-29 single fiber显示文摘 | Lei Zhenkun Wang Quan Kang Yilan | 2010 | Optics and Lasers in Engineering2010，48，1： | 1 |
| 13 | Experimental study of the Raman strain rosette based on the carbonnanotube strain sensor显示文摘 | QIU Wei KANG Yilan LEI Zhenkun | 2010 | Journal of Raman Spectroscopy*2010，41，10： | 1 |
| 14 | Stress transfer of single fiber/microdroplet tensile test studied by micro-Raman spectroscopy显示文摘 | LEI Zhenkun QIU Wei KANG Yilan | 2008 | Composites Part A: Applied Science and Manufacturing2008，39，1： | 1 |
| 15 | Micromechanics analysis of Kevlar-29 aramid fiber and epoxy resin microdroplet composite by Micro-Raman spectroscopy 显示文摘 | CEN Hao KANG Yilan LEI Zhenkun | 2013 | Composite Structures2013，75，14： | 1 |
| 16 | Stress transfer of single fiber/microdroplet tensile test studied by micro- Raman spectroscopy 显示文摘 | Zhenkun Lei Wei Qiu Yilan Kang | 2008 | Composites Part A:Applied Sci- ence and Manufacturing2008，39，1： | 1 |
| 17 | Experimental investigation of interracial fracture behavior in foam core sandwich beams with visco-elastic adhesive interface显示文摘 | Wang Can Chen Haoran Lei Zhenkun | 2010 | Composite Structures2010，92，5： | 1 |
| 18 | Study of shear transfer in Al/epoxy joint bydigital photoelasticity 显示文摘 | Lei Zhenkun Yun Hai Zhao Yanru XingYongming Pan Xuemin | 2009 | Optics and Lasers inEngineering2009，47，6： | 1 |
| 19 | Stress transfer of single fiber/mierodroplet tensile test studied by micro-Raman spectroscopy 显示文摘 | Lei Zhenkun Qiu Wei Kang Yilan | 2008 | Composites2008，39，1： | 1 |
| 20 | Micromechanics of fiber- crack interaction studied by miero-Raman spectroscopy: Bridg- ing fiber显示文摘 | Lei Zhenkun Wang Quan Qiu Wei | 2013 | Opt Laser Eng2013，51，4： | 1 |
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