|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Emission characteristics and combustion instabilities in an oxy-fuel swirl-stabilized combustor显示文摘This paper presents an experimental study on the emission characteristics and combustion instabilities of oxy-fuel combustions in a swirl-stabilized combustor. Different oxygen concentrations (Xoxy=25%~45%, where Xoxy is oxygen concentra- tion by volume), equivalence ratios (φ=0.75~1.15) and combustion powers (CP=1.08~2.02 kW) were investigated in the oxy-fuel (CH4/CO2/O2) combustions, and reference cases (Xoxy=25%~35%, CH4/N2/O2 flames) were covered. The results show that the oxygen concentration in the oxidant stream significantly affects the combustion delay in the oxy-fuel flames, and the equivalence ratio has a slight effect, whereas the combustion power shows no impact. The temperature levels of the oxy-fuel flames inside the combustion chamber are much higher (up to 38.7%) than those of the reference cases. Carbon monoxide was vastly produced when Xoxy>35% or φ>0.95 in the oxy-fuel flames, while no nitric oxide was found in the exhaust gases because no N2 participates in the combustion process. The combustion instability of the oxy-fuel combustion is very different from those of the reference cases with similar oxygen content. Oxy-fuel combustions excite strong oscillations in all cases studied Xoxy=25%~45%. However, no pressure fluctuations were detected in the reference cases when Xoxy>28.6% accomplished by heavily sooting flames which were not found in the oxy-fuel combustions. Spectrum analysis shows that the frequency of dynamic pressure oscillations exhibits randomness in the range of 50~250 Hz, therefore resulting in a very small resultant amplitude. Temporal oscillations are very strong with amplitudes larger than 200 Pa, even short time fast Fourier transform (FFT) analysis (0.08 s) shows that the pressure amplitude can be larger than 40 Pa. | Guo-neng LI Hao ZHOU Ke-fa CEN | 2008 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2008，9，11： | 9 |
| 3 | Discovery of Wolitu Pb-Zn deposit through geochemical prospecting under loess cover in Inner Mongolia, China显示文摘We report the finding of the Wolitu Pb-Zn deposit in Inner Mongolia, China, through a series of geochemical surveys. The Wolitu area, located in the loess-cover area in the Hure Banner, Tongliao City,Inner Mongolia, and neighboring the Horqin Sandy Land to the north, had no previous history of Pb-Zn mining or record of Pb-Zn mineralization. Our study identified a large Pb-Zn anomaly with potential zones of mineralization by stream sediment survey. Random rock sampling reveals limonitization at sporadic outcrops in the gullies. The high concentrations of Pb in the residual debris provided guidelines to fix the position for exploratory trench. Oxidized concealed orebodies were identified by trenching.Blind orebodies in veins hosted within the structural zone between slates and marbles of the upper Carboniferous Shizuizi Formation and the Permian granite were discovered by drilling. It is computed that the ore reserve may reach up to 540,000 tones with Pb grade of 1.27% and Zn of 1.9%. This case study is an excellent example for identifying potential polymetallic deposits in loess covered terrains using geochemical exploration. | Fan Yang Mu Kong Huazhong Liu Jinsong Yu Shaoping Yang Zhihong Hao Dehui Zhang Kuang Cen | 2017 | Geoscience Frontiers2017，8，5： | 3 |
| 4 | Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats显示文摘 | Li-fang ZHANG Ling-sheng LIU Xiao-man CHU Hao XIE Li-juan CAO Cen GUO Ji-ye A Bei CAO Meng-jie LI Guang-ji WANG Hai-ping HAO | 2014 | Acta Pharmacologica Sinica2014，35，3： | 3 |
| 5 | Differentially Expressed microRNAs as Potential Markers for Vital Reaction of Burned Skin显示文摘The identification of antemortem burns and postmortem burns is essential in forensic practice.In this study,microRNA(miRNA)microarray analysis was conducted to identify differentially expressed miRNAs in the skin of an experimental burn model.Microarray analysis revealed 24 differentially expressed miRNAs in antemortem burned mice skin,with 19 miRNAs significantly upregulated and 5 downregulated.Based on the intersection predicted using three databases(Targetscan,microRNA.org,and PITA),293 potential miRNA targets were identified.These dysregulated miRNAs and their predicted targets were further analyzed using the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases.Several functional categories and signaling pathways were enriched,including the“fc epsilon ri signaling pathway,”“endometrial cancer,”and“mTOR signaling pathway.”Expression patterns of 10 differentially expressed miRNAs were verified by reverse transcription‑quantitative polymerase chain reaction in mice skins.The results agreed with the results of microarray analysis.These findings suggest that differentially expressed miRNAs revealed by microarray are potential markers for forensic molecular diagnosis of antemortem burns. | Hao‑Pin Lyu Ming Cheng Jin‑Cen Liu Ming‑Yuan Ye Di Xu Jie‑Tao He Xiao‑Li Xie Qi Wang | 2018 | Journal of Forensic Science and Medicine2018，4，3： | 2 |
| 6 | A molecular roadmap for induced multi-lineage transdifferentiation of fibroblasts by chemical combinations显示文摘 | Xiaoping Han Hao Yu Daosheng Huang Yang Xu Assieh Saadatpour Xia Li Lengmei Wang Jie Yu Luca Pinello Shujing Lai Mengmeng Jiang Xueying Tian Fen Zhang Yanhong Cen Yuko Fujiwara Wei Zhu Bin Zhou Tianhua Zhou Hongwei Ouyang Jianan Wang Guo-Cheng Yuan Shumin Duan Smart H Orkin Guoji Guo | 2017 | Cell Research2017，27，3： | 2 |
| 7 | Modeling and optimization of the NOx emission characteristics of a tangentially fired boiler with arti-ficial neural networks 显示文摘 | ZHOU Hao CEN Ke-fa FAN Jian-ren | 2004 | Energy2004，29，1： | 1 |
| 8 | A comparative study of optimization algorithms for low NOx combustion modification at a coal-fired utility boiler显示文摘 | Li-Gang Zheng Hao Zhou Ke-Fa Cen Chun-Lin Wang | 2009 | Expert Systems with Applications2009，36，2： | 1 |
| 9 | Jianren fan modeling and optimization of the NOx emission characteristics of a tangentially fired boiler with artificial neural networks 显示文摘 | Hao Zhao Kefa Cen | 2004 | Energy2004，，29： | 1 |
| 10 | Combining neural and genetic algorithms to optimize low NOx ulverized coal combustion 显示文摘 | ZHOU Hao CEN Ke-fa MAO Jian-bo | 2001 | Fuel2001，，80： | 1 |
| 11 | Modeling and optimization of the NOx emission characteristics of a tangentially fired boiler with artificial neural networks显示文摘 | Hao Zhou Kefa Cen Jianren Fan | 2003 | Energy2003，，1： | 1 |
| 12 | Optimizing pulverized coal combustion performance based on ANN and GA显示文摘 | Zhou Hao Qian Xinping Cen Kefa | | 0，，1： | 1 |
| 13 | Kinetics and mechanism of the sulfurization behavior of silver conductive material in automobile industry显示文摘As a functional material,silver was employed as the electrical contact material in automotive electronics due to the excellent conductivity.However,this material was prone to the atmospheric corrosion,resulting in the damage of structure and failure of devices.In this study,the corrosion behavior of conductive silver applied in printed circuit board was explored,and it was found that the strongest environmental factors(SO2 pollutants,temperature and relative humidity(RH))influenced the structural damage of material on the viewpoints of kinetics and mechanism.Compared with other factors,temperature(55℃)was the dominating factor causing the structural change of conductive material under operation environments,and the corrosion product on the surface reached the maximum at the thickness of different corrosion product layer of dfilm=15.56910-5 lm.However,SO2 pollutants and RH accordingly increase the thickness of corrosion products(Ag2S and Ag_(2)SO_(4))during corrosion process,due to the promotion of the diffusion of corrosive species.Therefore,this study not only significantly reinforces the understanding of the structural damage of conductive material among the different environmental factors,but also provides an important guide to corrosion prevention design and materials selection in actual manufacturing. | Ze-Di Shi Le Zhang Yue-Long Ma Tian-Yuan Zhou Bing-Heng Sun Cen Shao Guo-Can Huang Shi-Tong Yin Su-Dan Hou Zeng-Wang Yang Hao Chen | 2022 | Rare Metals2022，41，1： | 1 |
| 14 | Modeling and optimization of the NOx emission characteristics of a tangentially fired boiler with artificial neural networks 显示文摘 | Hao Zhou Kefa Cen Jianren Fan | 2004 | Energy2004，29，： | 1 |
| 15 | Modeling and optimization of the NOx emission characteristics of a tangentially fired boiler with artificial neural networks显示文摘 | Zhou Hao Cen Kefa Fan Jianren | 2004 | Energy2004，29，1： | 1 |
| 16 | Combining support vector regression and ant colony optimization to reduce NOx emissions in coal-fired utility boilers显示文摘 | Zheng Ligang Zhou Hao Wang Chunling Cen Kefa | 2008 | Energy & Fuels2008，22，2： | 1 |
| 17 | A comparative study of optimization algorithms for low NOx combustion modification at a coal-fired utility boiler显示文摘 | Zheng Lingang Zhou Hao Cen Kefa Wang Chunlin | 2009 | Expert Systems with Applications2009，36，2： | 1 |
| 18 | Optimizing Pulver- ized Coal Combustion Performance Base on ANNand GA显示文摘 | Zhou Hao Qin Xinping Cen Kefa | 2004 | Fuel Processing Technology2004，，2： | 1 |
| 19 | Computational intelligence approach for NOx emissions minimization in a coal-fired utility boiler显示文摘 | Zhou Hao Zheng Ligang Cen Kefa | 2010 | Energy Conversion and Management2010，51，3： | 1 |
| 20 | Optimizing pulverized coalcombustion performance based on ANN and GA显示文摘 | Zhou Hao Qian Xinping Cen Kefa | 2003 | Fuel ProcessingTechnology2003，85，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员