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您的检索式：作者名="Leibing Li"
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| 1 | Lactobacillus fermentum as a new inhibitor to control advanced glycation end-product formation during vinegar fermentation显示文摘The inhibitory activity of lactic acid bacteria(LAB)toward advanced glycation end-products(AGEs)during vinegar fermentation was studied,and its relationships with the substrate consumption,antioxidant capacity,total phenolic content,total flavonoid compounds,α-glucosidase,andα-amylase activity inhibition were evaluated.The vinegar was made from rice powder flour by liquid-state fermentation(LSF).The selected LAB strains were separately co-cultivated with Saccharomyces cerevisiae and Acetobacter pasteurianus 1.41 in alcoholic and acetic acid fermentation,respectively.Among 3 strains,Lactobacillus fermentum showed the strongest inhibitory effect on the formation of total fluorescent AGEs and carboxymethyl lysine(CML)/carboxyethyl lysine(CEL)in the fermentation process.The corresponding mechanisms included the acceleration of substrate consumtion,improvement of antioxidant activities,and inhibition ofα-glucosidase andα-amylase.In addition,the fluorescent AGEs and the CML/CEL were negatively correlated with the antioxidant activities,while theα-glucosidase andα-amylase activities were positively correlated with the total phenols and total flavonoids.Moreover,the variety of main flavor compounds increased,including esters,alcohols,phenols and acids.The results of the study support the potential use of screened LAB strains to inhibit the formation of fluorescent AGEs,CML and CEL on fermented products and in the food processing industry,without associated risks to consumers. | Qin Li Leibing Li Hanjian Zhu Fan Yang Ke Xiao Lin Zhang Menglin Zhang Yongsheng Peng Chao Wang Dongsheng Li Qian Wu Mengzhou Zhou | 2022 | Food Science and Human Wellness2022，11，5： | 0 |
| 2 | 人内皮反转录病毒K上调与肺动脉高压免疫和炎症相关显示文摘免疫失调与遗传性、特发性和其他情况导致的肺动脉高压(pulmonary arterial hypertension,PAH)中的闭塞性血管重塑有关。循环自身免疫抗体,肺部血管周围淋巴组织以及细胞因子升高都与PAH的病理机制有关,但是这些异常是怎样产生、维持并与疾病的发展联系在一起的仍不明确。为了了解这些问题,研究者将鉴别PAH中肺部特殊的免疫复合物的特异性靶抗原作为出发点,来更好地为未来的免疫调节治疗的应用提供基础。 | 黄洁 叶鹏 Saito T Miyagawa K Chen SY Tamosiuniene R Wang L Sharp O Samayoa E Harada D Moonen JAJ Cao A Chen PI Hennigs JK Gu M Li CG Leib RD Li D Adams CM Del Rosario PA Bill MA Haddad F Montoya JG Robinson W Fantl WJ Nolan GP Zamanian RT Nicolls MR Chiu CY Ariza ME Rabinovitch M | 2017 | 中华高血压杂志2017，25，10： | 0 |
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