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您的检索式：作者名="Lejian Lin"
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| 1 | Climatology of Cloud-base Height from Long-term Radiosonde Measurements in China显示文摘Clouds are critical to the global radiation budget and hydrological cycle, but knowledge is still poor concerning the observed climatology of cloud-base height(CBH) in China. Based on fine-resolution sounding observations from the China Radiosonde Network(CRN), the method used to estimate CBH was modified, and uncertainty analyses indicated that the CBH is good enough. The accuracy of CBH estimation is verified by the comparison between the sounding-derived CBHs and those estimated from the micro-pulse lidar and millimeter-wave cloud radar. As such, the CBH climatology was compiled for the period 2006–16. Overall, the CBH exhibits large geographic variability across China, at both 0800 Local Standard Time(LST) and 2000 LST, irrespective of season. In addition, the summertime cloud base tends to be elevated to higher altitudes in dry regions [i.e., Inner Mongolia and the North China Plain(NCP)]. By comparison, the Tibetan Plateau(TP),Pearl River Delta(PRD) and Sichuan Basin(SCB) have relatively low CBHs(< 2.4 km above ground level). In terms of seasonality, the CBH reaches its maximum in summer and minimum in winter. A low cloud base tends to occur frequently(> 70%) over the TP, PRD and SCB. In contrast, at most sites over the Yangtze River Delta(YRD) and the NCP, about half the cloud belongs to the high-cloud category. The CBH does not exhibit marked diurnal variation in summer, throughout all CRN sites, probably due to the persistent cloud coverage caused by the East Asia Summer Monsson. To the best of our knowledge, this is the first CBH climatology produced from sounding measurements in China, and provides a useful reference for obtaining observational cloud base information. | Yong ZHANG Lejian ZHANG Jianping GUO Jinming FENG Lijuan CAO Yang WANG Qing ZHOU Liangxu LI Bai LI Hui XU Lin LIU Ning AN Huan LIU | 2018 | Advances in Atmospheric Sciences2018，35，2： | 2 |
| 2 | Pathogenesis of premature coronary artery disease:Focus on risk factors and genetic variants显示文摘The development of premature coronary artery disease(PCAD)is dependent on both genetic predisposition and traditional risk factors.Strategies for unraveling the genetic basis of PCAD have evolved with the advent of modern technologies.Genome-wide association studies(GWASs)have identified a considerable number of common genetic variants that are associated with PCAD.Most of these genetic variants are attributable to lipid and blood pressure-related single-nucleotide polymorphisms(SNPs).The genetic variants that predispose individuals to developing PCAD may depend on race and ethnicity.Some characteristic genetic variants have been identified in Chinese populations.Although translating this genetic knowledge into clinical applications is still challenging,these genetic variants can be used for CAD phenotype identification,genetic prediction and therapy.In this article we will provide a comprehensive review of genetic variants detected by GWASs that are predicted to contribute to the development of PCAD.We will highlight recent findings regarding CAD-related genetic variants in Chinese populations and discuss the potential clinical utility of genetic variants for preventing and managing PCAD. | Haiming Wang Zifan Liu Junjie Shao Min Jiang Xuechun Lu Lejian Lin Lin Wang Qiang Xu Haomin Zhang Xin Li Jingjing Zhou Yundai Chen Ran Zhang | 2022 | Genes & Diseases2022，9，2： | 1 |
| 3 | Acute myeloid leukemia following a primary mediastinal germ cell tumor显示文摘Introduction:There is a known association between primary mediastinal germ cell tumor(PMGCT)and hematologic malignancy that is not linked to treatment.They are exceptionally rare entities with a low morbidity and a poor prognosis.Case presentation:An 11-year-old boy presented with an anterior mediastinal mass diagnosed as a malignant germ cell tumor on the basis of an excisional biopsy.He was found to have acute myeloid leukemia(AML)two years after the chemotherapy for his germ cell tumor.The clinical course was very aggressive with a survival time of only 1 week after diagnosis of AML associated with PMGCT.Conclusion:AML associated with PMGCT needs to be diagnosed correctly.Relevant examinations should be carried out in patients with PMGCTs during and after chemotherapy,and long-term follow-up is still necessary to reduce the risk of morbidity and mortality. | Huimin Hong Yan Su Chenghao Chen Lejian He Shuai Zhu Wei Lin Mei Jin Xisi Wang Ruidong Zhang Huyong Zheng Qi Zeng Xiaoli Ma | 2020 | Pediatric Investigation2020，4，3： | 1 |
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