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| 1 | STUDY ON MECHANISM OF ARC-EXCITED ULTRASONIC显示文摘0INTRODUCTIONAnelectricalarccanbeidentifiedasadynamicresistanceinanarcweldingcircuit.Itistriedsucesfulyintungsteninertgasarcw... | Wu Minsheng Wang Zhengxian Li Luming Sun Diqing Duan Xiangyang Department of Mechanical Engineering, Qinghua University | 1999 | Chinese Journal of Mechanical Engineering1999，12，1： | 8 |
| 2 | Occurrence of Different Forms and Implications of Compound Specific Sterols in Continental Sediments of the Northeast South China Sea显示文摘The South China Sea(SCS) is one of the most productive and accumulative marginal shelves of organic carbon in the world. To expound the transformation and preservation of organic carbon in the Northeast SCS, where abundant oil and gas resources have been reported, compound specific sterols in free(FR), base hydrolytic(BH), and acid hydrolytic(AH) forms were analyzed in surface and columnar sediments in May, 2016. The results showed that the total contents of sterols detected ranged from 0.15 to 3.74 ppm dry weight in the surface sediments, and gradually decreased from 3.41 to0.17 ppm dry weight from surface to deep sediments, in which cholesterol(27^(△5)) was the most abundant component. Sterols mainly existed in the BH form(54.51%-74.20%), followed by the FR form(25.50%-45.49%) and then the AH form(0-3.77%) in turn, in the surface sediments. BH and FR sterols accounted for 0-49.08% and 50.92%-100% in the columnar sediments, while AH sterols were undetectable. The contents of specific sterols indicated that, the primary source of marine organic carbon was about 5 times as much as that from terrestrial input. More and more FR sterols transformed into BH sterols with increasing sedimentary depth, and BH sterols absolutely dominated in sediment depths under 25 cm. The forms of Sterols C27 were maintained at a relative consistence state, but Sterols C28 to C30 degraded gradually during the sedimentation process. It was suggested that the stability of sterols, based on the chemical structures, might be the primary factor controlling their degradation and preservation in deeper sediments. These results would help to understand the organic carbon(OC) transformation in a hydrate formation area in a marginal sea. | QIU Hong ZOU Li ZHANG Minsheng ZHU Chaoqi JIA Yonggang | 2019 | Acta Geologica Sinica(English Edition)2019，93，2： | 6 |
| 3 | CYCLIC HARDENING BEHAVIOR OF POLYCRYSTALS WITH PENETRABLE GRAIN BOUNDARIES:TWO-DIMENSIONAL DISCRETE DISLOCATION DYNAMICS SIMULATION显示文摘由 Giessen 和裁缝( 1995 )的一种二维的分离脱臼动力学( DDD )技术,被集成一个脱臼谷物边界相互作用模型扩大了,习惯于计算联盟者分析包含微米大小的谷物的多晶体的微周期的塑料反应,与到多晶体和内在的脱臼机制的微塑料的周期的回答上的脱臼可穿透的谷物边界( GB )的重要影响的特殊注意。近这结束,在装载的简单紧张压缩下面的一个典型多晶的矩形的标本被考虑。结果显示出那,随积聚的紧张,不断的脱臼累积和提高的脱臼脱臼相互作用导致周期的变硬的周期的增加行为;然而,当在脱臼成核,通过 GB 的穿入和脱臼歼灭之中的动态平衡近似被建立时,周期的应力逐渐地趋于浸透。另外,包括谷物尺寸,周期的紧张振幅和它的历史,另外的因素也在周期的变硬和浸透上有可观的影响。 | Chuantao Hou Zhenhuan Li Minsheng Huang Chaojun Ouyang | 2009 | Acta Mechanica Solida Sinica2009，22，4： | 2 |
| 4 | Fabrication of Tβ4-Exosome-releasing artificial stem cells for myocardial infarction therapy by improving coronary collateralization显示文摘Currently,stem cell transplantations in cardiac repair are limited owing to disadvantages,such as immunological rejection and poor cell viability.Although direct injection of exosomes can have a curative effect similar to that of stem cell transplantation,high clearance hinders its application in clinical practice.Previous reports suggested that induction of coronary collateralization can be a desired method of adjunctive therapy for someone who had missed the optimal operation time to attenuate myocardial ischemia.In this study,to mimic the paracrine and biological activity of stem cells,we developed artificial stem cells that can continuously release Tβ4-exosomes(Tβ4-ASCs)by encapsulating specific exosomes within microspheres using microfluidics technology.The results show that Tβ4-ASCs can greatly promote coronary collateralization in the periphery of the myocardial infarcted area,and its therapeutic effect is superior to that of directly injecting the exosomes.In addition,to better understand how it works,we demonstrated that the Tβ4-ASC-derived exosomes can enhance the angiogenic capacity of coronary endothelial cells(CAECs)via the miR-17-5p/PHD3/Hif-1αpathway.In brief,as artificial stem cells,Tβ4-ASCs can constantly release functional exosomes and stimulate the formation of collateral circulation after myocardial infarction,providing a feasible and alternative method for clinical revascularization. | Peier Chen Xiaodong Ning Weirun Li Yuxuan Pan Ling Wang Hekai Li Xianglin Fan Jiexin Zhang Tiantian Luo Yaobin Wu Caiwen Ou Minsheng Chen | 2022 | Bioactive Materials2022，7，8： | 2 |
| 5 | Genomic Variations in the Tea Leafhopper Reveal the Basis of Its Adaptive Evolution显示文摘Tea green leafhopper(TGL),Empoasca onukii,is of biological and economic interest.Despite numerous studies,the mechanisms underlying its adaptation and evolution remain enigmatic.Here,we use previously untapped genome and population genetics approaches to examine how the pest adapted to different environmental variables and thus has expanded geographically.We complete a chromosome-level assembly and annotation of the E.onukii genome,showing notable expansions of gene families associated with adaptation to chemoreception and detoxification.Genomic signals indicating balancing selection highlight metabolic pathways involved in adaptation to a wide range of tea varieties grown across ecologically diverse regions.Patterns of genetic variations among 54 E.onukii samples unveil the population structure and evolutionary history across different tea-growing regions in China.Our results demonstrate that the genomic changes in key pathways,including those linked to metabolism,circadian rhythms,and immune system functions,may underlie the successful spread and adaptation of E.onukii.This work highlights the genetic and molecular basis underlying the evolutionary success of a species with broad economic impacts,and provides insights into insect adaptation to host plants,which will ultimately facilitate more sustainable pest management. | Qian Zhao Longqing Shi Weiyi He Jinyu Li Shijun You Shuai Chen Jing Lin Yibin Wang Liwen Zhang Guang Yang Liette Vasseur Minsheng You | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 1 |
| 6 | Atomistic modeling of the interaction between matrix dislocation and interfacial misfit dislocation networks in Ni-based single crystal superalloy显示文摘 | Yaxin Zhu Zhenhuan Li Minsheng Huang | 2013 | Computational Materials Science2013，，： | 1 |
| 7 | INFLUENCES OF MICROSCOPE SIZE EFFECT OF MATRIX ON PLASTIC POTENTIAL AND VOID GROWTH OF POROUS MATERIALS显示文摘Based on approximate theoretical analyses on atypieal spherical cell containing a sphericalmicrovoid,the influences of matrix materials’ microscopic scale on the macroscopic constitutive potential the-ory of porous material and microvoid growth have been investigated in detail.By assuming that the plastic de-formation behavior of matrix materials follows the strain gradient (SG) plastic theory involving the stretch androtation gradients,the ratio (λ=l/a) of the matrix materials’ intrinsic characteristic Length l to the micro-void radius a is introdnced into the plastic constitutive potential and the void grroth law.The present resultsindicate that,when the radius a of microvoids is comparable with the intrinsic characteristic length l of thematrix materials,the influence of microscopic size effect on neither the constitutive potential nor the micro-void evolution predicted can he ignored.And when the void radius a is much lager than the intrinsic charac-teristic length l of the matrix materials,the present model can retrogress automatically to the improved Gur-son model that takes into account the strain hardening effect of matrix materials. | Huang Minsheng Li Zhenhuan Wang Cheng Chen Chuanyao | 2002 | Acta Mechanica Solida Sinica2002，15，4： | 1 |
| 8 | Integrative transcriptomic and metabolomic analyses reveal the flavonoid biosynthesis of Pyrus hopeiensis flowers under cold stress显示文摘Low temperature is among the most restrictive factors to limit the yield and distribution of pear. Pyrus hopeiensis is a valuable wild resource.PCA showed that P. hopeiensis had strong cold resistance. In this study, the mRNA and metabolome sequencing of P. hopeiensis flower organs exposed to different low temperatures were performed to identify changes of genes and metabolites in response to low-temperature stress. A total of 4 851 differentially expressed genes(DEGs) were identified. Trend analysis showed that these DEGs were significantly enriched in profiles 19, 18, 7, 14, 1, 4 and 11. And the KEGG enrichment analysis showed that the DEGs in profile 18 were significantly enriched in flavone and flavonol biosynthesis. Besides, the expressed trends as well as GO and KEGG functional enrichment analyses of DEGs under cold and freezing stress showed significantly difference. Analyses of flavonoid-related pathways indicated that flavonoid structural genes had undergone significant changes. Correlation analysis showed that b HLH and MYB TFs may affect flavonoid biosynthesis by regulating structural gene expression. And PhMYB308 and PhMYB330 were likely candidate repressors of flavonoid biosynthesis by binding to a specific site in bHLH proteins. In total, 92 differentially accumulated metabolites(DAMs) were identified in P. hopeiensis flowers including 12 flavonoids. WGCNA results showed that coral 1, pink and brown 4 modules were closely associated with flavonoids and 11 MYBs and 15 bHLHs among the three modules may activate or inhibit the expression of 23 structural genes of flavonoid biosynthesis. Taken together, the results of this study provided a theoretical basis for further exploration of the molecular mechanisms of flavonoid biosynthesis and cold resistance of P. hopeiensis flower organs and our findings laid a foundation for further molecular breeding in cold-resistant pear varieties. | Yongtan Li Jun Zhang Shijie Wang Haie Zhang Yichao Liu Minsheng Yang | 2023 | Horticultural Plant Journal2023，9，3： | 1 |
| 9 | Quantitative study on interactions between interfacial misfit dislocation networks and matrix dislocations in Ni-based single crystal superalloys显示文摘The interactions between the moving dislocation within matrix channel and the interfacial misfit dislocation networks on the two-phase interfaces in Ni-based single crystal superalloys are studied carefully via atomic modeling, with special focus on the factors influencing the critical bowing stress of moving dislocations in the matrix channel. The results show that the moving matrix dislocation type and its position with respect to the interfacial misfit dislocation segments have considerable influences on the interactions. If the moving matrix dislocation is pure screw, it reacts with the interfacial misfit dislocation segments toward dislocation linear energy reduction, which decreases the critical bowing stress of screw dislocation due to dislocation linear energy release during the dislocation reactions. If the moving matrix dislocation is of 60°-mixed type, it is obstructed by the interaction between the mixed matrix dislocations and the misfit interfacial dislocation segments. As a result, the critical bowing stress increases significantly because extra interactive energy needs to be overcome. These two different effects on the critical bowing stress become increasingly significant when the moving matrix dislocation is very close to the interfacial misfit dislocation segments. In addition, the matrix channel width also has a significant influence on the critical bowing stress, i.e. the narrower the matrix channel is, the higher the critical bowing stress is. The classical Orowan formula is modified to predict these effects on the critical bowing stress of moving matrix dislocation, which is in good agreement with the computational results. | Jun Xiong Yaxin Zhu Zhenhuan Li Minsheng Huang | 2017 | Acta Mechanica Solida Sinica2017，30，4： | 1 |
| 10 | Neuropeptide Y induces cardiomyocyte hypertrophy via calcineurin 显示文摘 | Minsheng Chen Xiaoyun Li Qi Dong | 2005 | Regul Pept2005，125，13： | 1 |
| 11 | Elevated ZIPK is required for TNF-α-induced cell adhesion molecule expression and leucocyte adhesion in endothelial cells显示文摘Leucocyte adhesion to the vascular endothelium is a critical event in the early inflammatory response to infection and injury.This process is primarily regulated by the expression of cell adhesion molecules(CAMs)in endothelial cells.It has been well documented that tumor necrosis factor alpha(TNF-α)is a key regulator of CAM expression within this process,but its regulatory mechanism remains controversial.To investigate the scenario within this process,we assessed the role of zipper-interacting protein kinase(ZIPK),a serine/threonine kinase with multiple substrates,in CAM expression.We used TNF-αas inflammatory stimulator and found that ZIPK was integrated into the signaling regulation of TNF-α-mediated CAM expression.In human umbilical vein endothelial cells(HUVECs),TNF-αexposure led to significantly increased expression of both intercellular CAM-1(ICAM-1)and vascular CAM-1(VCAM-1),along with an increase in the adhesion of THP-1 monocytes to HUVECs.Simultaneously,ZIPK gene was also up-regulated at the transcription level.These effects were clearly inhibited by the ZIPK-specific inhibitor Tc-DAPK6 or small interfering RNA(siRNA)capable of specifically inhibiting ZIPK expression.We thus suggest that both ZIPK activation and ZIPK gene expression are necessary for TNF-α-mediated CAM expression and leucocyte adhesion.Interestingly,ZIPK inhibition also significantly suppressed TNF-α-induced nuclear factor kappa B(NF-κB)activation,indicating that TNF-α-mediated ZIPK expression functions upstream of NF-κB and CAM expression.We thus propose a TNF-α/ZIPK/NF-κB signaling axis for CAM expression that is necessary for leucocyte adhesion to endothelial cells.Our data in this study revealed a potential molecular target for exploring anti-inflammation drugs. | Weiwei Zeng Zhiyuan Sun Tengxiang Ma Xiaobin Song Shuai Li Qianqian Zhang Wen Yuan Jing Li Li Liu Minsheng Zhu Huaqun Chen | 2021 | Acta Biochimica et Biophysica Sinica2021，53，5： | 1 |
| 12 | Neuropeptide Y Induces Cardiomyocyte Hypertrophy via Calcineurin Signaling in Rats显示文摘 | MINSHENG CHEN XIAOYUN LI QI DONG | 2005 | Regulatory Peptides2005，125，： | 1 |
| 13 | Neuropeptide Y induces cardiomyocyte hypertrophy via calcineurin signaling in rats显示文摘 | Minsheng Chen Xiaoyun Li Qi Dong | 2005 | Regul Pept2005，125，： | 1 |
| 14 | Ultrasonic generation by exciting electric arc: a tool for grain refinement in welding process显示文摘 | He Longbiao Wu Minsheng Li Luming | 2006 | Applied Physics Letters2006，89，13： | 1 |
| 15 | MiR-23a inhibits myogenic differentiation through down regulation of fast myosin heavy chain isoforms显示文摘 | Li Wang Xin Chen Yanyan Zheng Fen Li Zheng Lu Chen Chen Jin Liu Yu Wang Yajing Peng Zhongliang Shen Jiming Gao Minsheng Zhu Huaqun Chen | 2012 | Experimental Cell Research2012，，18： | 1 |
| 16 | Neuropeptide Y induces cardiomyocyte hypertrophy via calcineurin signaling in rats显示文摘 | Minsheng Chen Xiaoyun Li Qi Dong | 2005 | Regulatory Peptides2005，，125： | 1 |
| 17 | Transferred power control for ICPT pick-ups utilizing dynamically switched inductor显示文摘 | Yang Minsheng Li Xiaofeng Ao Zhanghong | 2012 | Energy Procedia2012，，： | 1 |
| 18 | Effects of strain,nutrients concentration and inoculum size on microalgae culture for bioenergy from post hydrothermal liquefaction wastewater显示文摘Cultivating microalgae in post hydrothermal liquefaction wastewater(PHWW)offers many benefits,including nutrients recovery and reuse,wastewater purification and biomass production.However,the high nutrients concentration and toxic substances in PHWW undermine the efficiency of biomass production and nutrient recovery.This study aimed to investigate the effects of the microalgae strains,initial nutrients concentrations and inoculum sizes on biomass production and nutrient recovery using PHWW as the cultivation medium.Results indicated that both biomass production and nutrients recovery were successfully improved by using the screened microalgae strain at the desirable initial nutrient concentration with the suggested algae inoculum size.Chlorella vulgaris 1067 probably demonstrated the strongest tolerance ability among the five microalgae strains screened,and performed well in the diluted PHWW,of which initial TN concentration was approximately 500 mg/L.The desirable inoculum size was determined to be 0.103-0.135 g/L.The biomass daily productivity was increased by 15.67-fold(reached 0.13 g/(L·d)).With the above optimal conditions,high biomass production and nutrient recovery from the PHWW to produce microalgae biomass for bioenergy production were achieved. | Zhang Li Lu Haifeng Yuanhui Zhang Ma Shanshan Li Baoming Liu Zhidan Duan Na Liu Minsheng Si Buchun Lu Jianwen | 2017 | International Journal of Agricultural and Biological Engineering2017，10，2： | 1 |
| 19 | Preservation of Lipid Molecular Fossils in the Sediments from an Oil-Gas Releasing Zone in the South China Sea显示文摘In order to explore the standing stock and preservation of organic carbon, different forms of compound specific lipids were analyzed, based on a 1.8 m sediment core collected in the northern continental shelf of South China Sea in May, 2016. In the core sediments, 21 species of fatty acids, 6 species of alcohols, 8 species of sterols and phytol were detected. Fatty acids were dominated components with the percent of 67%–91% in the total lipids, in which saturated fatty acid C16:0 accounted for about 50%. The contents of lipid species generally decreased from the sediments at surface to those deep, except alcohols waving in a certain range at the same time. Fatty acids primarily existed in free form, followed by base hydrolytic form, and then acid hydrolytic form. Free alcohols were obviously dominated, while base and acid hydrolytic forms contributed small comparably. Phytol gave a significant priority to base hydrolytic form, while acid hydrolytic form could be neglected. Similar to phytol, sterols mostly presented in base hydrolytic form, and then in free form. The compositions of lipids and their forms suggested that organic carbon basically originated from primary production in upper waters in studying area, and were well preserved in the sediments. | QIU Hong ZOU Li ZHANG Minsheng ZHU Chaoqi JIA Yonggang | 2018 | Journal of Ocean University of China2018，17，6： | 0 |
| 20 | Effects of site conditions on growth and wood properties of Populus×euramericana cv.'74/76'显示文摘The growth and wood properties of 240 individual Populus×euramericana cv.’74/76’(hereafter poplar 107)trees planted in Hebei Plain,China was evaluated.Mean annual increments in height,breast height diameter and volume,as well as cellulose,hemicellulose and lignin contents,shrinkage,density,bending strength and modulus of elasticity in the heart wood and sap wood.Environmental factors influencing growth and wood properties were analyzed using correlation and stepwise regres sion.The results show that the coefficients of variation(CVs)of growth traits ranged from 10.6 to 22.4%.The CVs of the chemical properties of heartwood ranged from 4.3 to 30.2%,and for sap wood from 3.2 to 27.5%.The CVs of the physical and mechanical properties of heartwood ranged from 8.6 to 31.7%,and for sapwood from 6.4 to 29.9%.The results of one-way ANOVA showed that there were significant differences in growth traits and wood properties among sites.Soil pH,total and available phosphorus,total potassium,and soil organic matter were key soil factors affecting growth and wood properties of poplar 107,whereas mean annual ground temperatures and precipitation were the main climatic factors.To better cultivate poplar 107,area with less annual rainfall,slightly higher temperature and soil pH value close to neutral should be selected. | Jianmin Fan Changjun Ding Shijie Wang Changming Ma Chao Zhang Yongtan Li Jinmao Wang Minsheng Yang Xiaohua Su | 2023 | Journal of Forestry Research2023，34，2： | 0 |
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