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| 1 | Bacterial biota in reflux esophagitis and Barrett's esophagus显示文摘AIM: To identify the bacterial flora in conditions such as Barrett's esophagus and reflux esophagitis to determine if they are similar to normal esophageal flora.METHODS: Using broad-range 16S rDNA PCR,esophageal biopsies were examined from 24 patients [9with normal esophageal mucosa, 12 with gastroesophageal reflux disease (GERD), and 3 with Barrett's esophagus].Two separate broad-range PCR reactions were performed for each patient, and the resulting products were cloned.In one patient with Barrett's esophagus, g9 PCR clones were analyzed.RESULTS: Two separate clones were recovered from each patient (total = 48), representing 24 different species, with 14 species homologous to known bacteria,5 homologous to unidentified bacteria, and 5 were not homologous (<97% identity) to any known bacterial 16S rDNA sequences. Seventeen species were found in the reflux esophagitis patients, 5 in the Barrett's esophagus patients, and 10 in normal esophagus patients.Further analysis concentrating on a single biopsy from an individual with Barrett's esophagus revealed the presence of 21. distinct bacterial species. Members of four phyla were represented, including Bacteroidetes,Firmicutes, Proteobacteria, and Actinobacteria.Microscopic examination of each biopsy demonstrated bacteria in intimate association with the distal esophageal epithelium, suggesting that the presence of these bacteria is not transitory.CONCLUSION: These findings provide evidence for a complex, residential bacterial population in esophageal reflux-related disorders. While much of this biota is present in the normal esophagus, more detailed comparisons may help identify potential disease associations. | Zhiheng Pei Liying Yang Richard M Peek Jr Steven M Levine David T Pride Martin J Blaser | 2005 | World Journal of Gastroenterology2005，11，46： | 11 |
| 2 | An optimal basis of band-limited functions for signal analysis and design显示文摘 | Wei Liying KENNEDY R A LAMAHEWA T A | 2010 | IEEE Transactions on Signal Processing2010，58，11： | 1 |
| 3 | Immobilization of Streptomyces olivaceoviridis E-86 Xylanase on Eudragit S-100 for xylo-oligosaccharidc production 显示文摘 | AI Z L JIANG Z Q LIi L T | 2006 | Process Biotechnol2006，126，3： | 1 |
| 4 | An optimal basis of band-limited functions for signal analysis and design显示文摘 | Liying W Kennedy R A Lamahewa T A | 2010 | IEEE Transactions on Signal Processing2010，58，11： | 1 |
| 5 | The small world yields the mosteffective information spreading显示文摘 | Lii L Chen D B Zhou T | 2011 | New Journal of Physics2011，13，12： | 1 |
| 6 | A new robust narrowband active noise control system in the presence of frequency mismatch显示文摘 | Xiao Yegui Ma Liying Kho T K | 2006 | IEEE Transaction on Audio Speech and Language Processing2006，14，6： | 1 |
| 7 | Identifying Influential Spreaders by Weighted LeaderRank 显示文摘 | Li Q Zhou T Lii L Y | 2014 | Physica A: Statistical Mechanics and Its Applications2014，404，： | 1 |
| 8 | Stereological Measurement and Error Estimates for Three-Dimensional Fiber Orientation显示文摘 | BAY R S LII C L T | 1992 | Polymer Engineering & Science1992，32，4： | 1 |
| 9 | The Mo loading effect on SCR deNOx performance for V-W-Mo/TiO2 catalyst显示文摘 | Gao Y Luan T Lii T Xu H | | 0，，： | 1 |
| 10 | An induction motor position controller optimally designed with fuzzy phase-plane control and genetic algorithms显示文摘 | Lii G R Chiang C L Su C T | 2004 | Electronic Power Systems Research2004，68，： | 1 |
| 11 | Paraxial propagation of a partially coherent flattened Gaussian beam through apertured AB-CD optical systems显示文摘 | Cai Yangjian Lii Xiang Eyyuboglu H T | 2008 | Opt Commun2008，281，12： | 1 |
| 12 | A joint estimation approach for two-tone image deblurring by blind deconvolution显示文摘 | Li T H Lii K S | 2002 | Image Processin- g IEEE Transactions on2002，11，8： | 1 |
| 13 | The Mo loading effect on thermo stability and SO2 oxidation of SCR catalyst显示文摘 | Gao Y Luan T Lii T | 2012 | Advanced Materials Research2012，873，： | 1 |
| 14 | A note on fully polynomial-time approximation scheme for parallel-machine scheduling with deteriorating jobs显示文摘 | KANG Liying NG C T | 2007 | Int J Prod Econ2007，109，12： | 1 |
| 15 | Realliability Planning for Composite Electric Power System显示文摘 | Su C T Lii G R | 1999 | Electronic Power Systems Research1999，51，1： | 1 |
| 16 | Phase II trial of docetaxal plus imatinib mesylate in the treatment of patients with metastatic breast cancer显示文摘 | Yardley DA Burris lii HA Markus T | 2009 | Clin Breast Cancer2009，9，4： | 1 |
| 17 | A note on a fully polynomial-time approximation scheme for parallel scheduling with deteriorating jobs显示文摘 | KANG Liying NG C T | 2007 | Int J Prod Econ2007，109，： | 1 |
| 18 | Taxation without representation:peasants,the central and the local states in reform China显示文摘 | Bemstein T P LII X | 2000 | The China Quarterly2000，163，： | 1 |
| 19 | Potential theory for directed networks 显示文摘 | Zhang Q M Lii L Wang W Q Zhou T | 2013 | PIoS one2013，8，2： | 1 |
| 20 | Convergent responses of nitrogen and phosphorus resorption to nitrogen inputs in a semiarid grassland显示文摘 | Lii X T Reed S Yu Q | 2013 | Global Change Biology2013，19，9： | 1 |
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