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| 1 | Endoscopic submucosal dissection for early gastric cancer with undifferentiated-type histology:A meta-analysis显示文摘AIM: To evaluate the efficacy and safety of endoscopicsubmucosal dissection(ESD) for early gastric cancer(EGC) with undifferentiated-type histology.METHODS: A systematic literature review was conducted using the core databases. Complete resection,curative resection, en bloc resection, recurrence and adverse event rate were extracted and analyzed. A random effect model was applied. The methodological quality of the enrolled studies was assessed using the Newcastle-Ottawa Scale. Publication bias was evaluated using a funnel plot, the trim and fill method, Egger's test,and a rank correlation test.RESULTS: Fourteen retrospective studies between2009 and 2014 were identified(972 EGC lesions with undifferentiated-type histology). The total en bloc and complete resection rates were estimated as92.1%(95%CI: 87.4%-95.2%) and 77.5%(95%CI:69.3%-84%), respectively. The total curative resection rate was 61.4%(95%CI: 44.5%-75.9%). The overall recurrence rate was 7.6%(95%CI: 3.4%-16%).Limited to histologically diagnosed expanded-criteria lesions, the en bloc and complete resection rates were91.2% and 85.6%, respectively. The curative resection rate was 79.8%.CONCLUSION: In this analysis, ESD is a technically feasible treatment modality for EGC with undifferentiatedtype histology. Long-term studies are needed to confirm these therapeutic outcomes. | Chang Seok Bang Gwang Ho Baik In Soo Shin Jing Bong Kim Ki Tae Suk Jai Hoon Yoon Yeon Soo Kim Dong Joon Kim Woon Geon Shin Kyung Ho Kim Hak Yang Kim Hyun Lim Ho Seok Kang Jong Hyeok Kim Jin Bae Kim Sung Won Jung Sea Hyub Kae Hyun Joo Jang Min Ho Choi | 2015 | World Journal of Gastroenterology2015，21，19： | 14 |
| 2 | Ratio of metastatic lymph nodes is more important for rectal cancer patients treated with preoperative chemoradiotherapy显示文摘AIM:To evaluate the predictive value of the lymph node(LN) ratio(LNR,number of metastatic LNs/ examined LNs) for recurrence in patients with rectal cancer and to compare its applicability according to preoperative chemoradiotherapy(PCRT).METHODS:From 2000 to 2009,967 patients with metastatic LNs after curative resection for locally advanced rectal cancer were identified.Patients were categorized according to PCRT(PCRT vs No PCRT).The cut-off LNR was determined based on the p N1 vs p N2 when the recommended number of LNs was harvested.The 5-year recurrence-free survival(RFS) rates using the Kaplan-Meier method were compared according to p/yp N stage and the LNR in each group.RESULTS:Among patients with the same p/yp N stage,the 5-year RFS rate differed according to the LNR.In addition,the 5-year RFS rate was significantly different between p N and LNR groups in patients with No PCRT.In PCRT group,however,only LNR was associated with prognosis.On multivariate analysis,both p N and LNR were significant independent prognostic factors for 5-year RFS in the No PCRT group.In the PCRT group,only LNR category was found to be associated with RFS(HR = 2.36,95%CI:1.31-3.84,and P = 0.001).CONCLUSION:The LNR is an important prognostic predictor of RFS in rectal cancer patients especially treated with PCRT.Current p N categories could not discriminate between prognostic groups of RFS after PCRT. | In Ja Park Chang Sik Yu Seok-Byung Lim Yong Sik Yoon Chan Wook Kim Tae Won Kim Jong Hoon Kim Jin Cheon Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 8 |
| 3 | Five-year major clinical outcomes between first-generation ana second- generation drug-eluting stents in acute myocardial infarction patients underwent percutaneous coronary intervention显示文摘 | Yong Hoon Kim Ae-Young Her Seung-Woon Rha Byoung Geol Choi Se Yeon Choi Jae Kyeong Byun Ju Yeol Baek Woong Gil Choi Tae Soo Kang Ji Hoon Ahn Sang-Ho Park Ahmed Mashaly Jin Oh Na Cheol Ung Choi Hong Euy Lim Eung Ju Kim Chang Gyu Park Hong Seog Seo Dong Joo Oh | 2018 | Journal of Geriatric Cardiology2018，15，8： | 8 |
| 4 | Treatment for gastric ‘indefinite for neoplasm/dysplasia' lesions based on predictive factors显示文摘BACKGROUND Gastric ‘indefinite for neoplasm/dysplasia'(IFND) is a borderline lesion that is difficult to diagnose as either regenerative or neoplastic. There is a need for guidance in the identification of a subset of patients, who have an IFND lesion with a higher risk of malignant potential, to enable risk stratification and optimal management.AIM To determine the clinical and pathologic factors for the accurate diagnosis of gastric IFND lesions.METHODS In total, 461 gastric lesions diagnosed via biopsy as IFND lesions were retrospectively evaluated. Endoscopic resection(n = 134), surgery(n = 22), and follow-up endoscopic biopsy(n = 305) were performed to confirm the diagnosis.The time interval from initial biopsy to cancer diagnosis was measured, and diagnostic delays were categorized as > 2 wk, > 2 mo, > 6 mo, and > 1 year. The IFND lesions presenting as regenerating atypia(60%) or atypical epithelia(40%)at initial biopsy were adenocarcinomas in 22.6%, adenomas in 8.9%, and gastritis in 68.5% of the cases.RESULTS Four clinical factors [age ≥ 60 years(2.445, 95%CI: 1.305-4.580, P = 0.005),endoscopic size ≥ 10 mm(3.519, 95%CI: 1.891-6.548, P < 0.001), single lesion(5.702, 95%CI: 2.212-14.696, P < 0.001), and spontaneous bleeding(4.056, 95%CI:1.792-9.180, P = 0.001)], and two pathologic factors [atypical epithelium(25.575,95%CI: 11.537-56.695, P < 0.001], and repeated IFND diagnosis [6.022, 95%CI:1.822-19.909, P = 0.003)] were independent risk factors for gastric cancer. With two or more clinical factors, the sensitivity and specificity for carcinoma were91.3% and 54.9%, respectively. Ten undifferentiated carcinomas were initially diagnosed as IFND. In the subgroup analysis, fold change(5.594, 95%CI: 1.458-21.462, P = 0.012) predicted undifferentiated or invasive carcinoma in the submucosal layers or deeper. Diagnostic delays shorter than 1 year were not associated with worse prognoses. Extremely well-differentiated adenocarcinomas accounted for half of the repeated IFND cases and resulted in low diagnostic accuracy even on retrospective blinded review.CONCLUSION More than two clinical and pathologic factors each had significant cut-off values for gastric carcinoma diagnosis; in such cases, endoscopic resection should be considered. | Mi Jung Kwon Ho Suk Kang Hyeon Tae Kim Jin Woo Choo Bo Hyun Lee Sung Eun Hong Kun Ha Park Dong Min Jung Hyun Lim Jae Seung Soh Sung Hoon Moon Jong Hyeok Kim Hye-Rim Park Soo Kee Min Jin won Seo Ji-Young Choe | 2019 | World Journal of Gastroenterology2019，25，4： | 4 |
| 5 | Role of magnetic resonance cholangiopancreatography for choledocholithiasis: Analysis of patients with negative MRCP显示文摘 | Jae Hyuck Chang In Seok Lee Yeon Soo Lim Sung Hoon Jung Chang Nyol Paik Hyung Keun Kim Tae Ho Kim Chang Whan Kim Sok Won Han Myung-Gyu Choi In-Sik Jung | 2012 | Scandinavian Journal of Gastroenterology2012，，2： | 2 |
| 6 | Liver Stiffness Measurement Using Acoustic Radiation Force Impulse (ARFI) Elastography and Effect of Necroinflammation显示文摘 | Ki Tae Yoon Sun Min Lim Jun Yong Park Do Young Kim Sang Hoon Ahn Kwang-Hyub Han Chae Yoon Chon Mong Cho Jun Woo Lee Seung Up Kim | 2012 | Digestive Diseases and Sciences2012，，6： | 1 |
| 7 | Low grade chondrosarcoma of the nasal septum显示文摘Chondrosarcoma of the nasal septum is extremely rare. In some cases, it may be diff icult to preoperatively differentiate low grade chondrosarcoma from benign cartilaginous tumors such as chondroma. We report a case of low grade chondrosarcoma of the nasal septum with characteristic radiologic f indings. Characteristic radiologic f indings such as calcif ications on computed tomography scan and a ring-and-arc pattern on enhanced T1 weighted image were useful in the preoperative diagnosis of low grade chondrosarcoma of the septum. Awareness of radiologic f indings of low grade chondrosarcoma can help to make an accurate diagnosis and perform appropriate excision, leading to successful local control. | Dong Hoon Lee Se Hee Jung Tae Mi Yoon Joon Kyoo Lee Young Eun Joo Sang Chul Lim | 2013 | World Journal of Clinical Cases2013，1，1： | 1 |
| 8 | A New Suggestion for the Radiation Target Volume After a Subtotal Gastrectomy in Patients With Stomach Cancer显示文摘 | Heerim Nam Do Hoon Lim Sung Kim Won Ki Kang Tae Sung Sohn Jae Hyung Noh Yong Il Kim Chan Hyung Park Chul Keun Park Yong Chan Ahn Seung Jae Huh | 2008 | International Journal of Radiation Oncology Biology Physics2008，，2： | 1 |
| 9 | An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach显示文摘 | Sung Kim Do Hoon Lim Jeeyun Lee Won Ki Kang John S. MacDonald Chan Hyung Park Se Hoon Park Se-Hoon Lee Kihyun Kim Joon Oh Park Won Seog Kim Chul Won Jung Young Suk Park Young-Hyuck Im Tae Sung Sohn Jae Hyung Noh Jin Seok Heo Yong Il Kim Chul Keun Park Keu | 2005 | International Journal of Radiation Oncology Biology Physics2005，，5： | 1 |
| 10 | Effects of probiotics (cultured Lactobacillus subtilis/Streptococcus faecium) in the treatment of alcoholic hepatitis: randomized-controlled multicenter study显示文摘 | Sang Hak Han Ki Tae Suk Dong Joon Kim Moon Young Kim Soon Koo Baik Young Don Kim Gab Jin Cheon Dae Hee Choi Young Lim Ham Dong Hoon Shin Eun Ji Kim | 2015 | European Journal of Gastroenterology & Hepatology2015，，11： | 1 |
| 11 | Role of magnetic resonance cholangiopancreatography for choledocholithiasis: Analysis of patients with negative MRCP显示文摘 | Jae Hyuck Chang In Seok Lee Yeon Soo Lim Sung Hoon Jung Chang Nyol Paik Hyung Keun Kim Tae Ho Kim Chang Whan Kim Sok Won Han Myung-Gyu Choi In-Sik Jung | 2012 | Scandinavian Journal of Gastroenterology2012，，2： | 1 |
| 12 | Benefit of Systematic Segmentectomy of the Hepatocellular Carcinoma: Revisiting the Dye Injection Method for Various Portal Vein Branches显示文摘 | Keun Soo Ahn Koo Jeong Kang Tae Jun Park Yong Hoon Kim Tae Jin Lim Jung Hyeok Kwon | 2013 | Annals of Surgery2013，，6： | 1 |
| 13 | Long‐term outcomes in patients with locally advanced rectal cancer treated with preoperative chemoradiation followed by curative surgical resection显示文摘 | Seok‐Byung Lim Chang Sik Yu Yong Sang Hong Tae Won Kim Jong Hoon Kim Jin Cheon Kim | 2012 | J Surg Oncol2012，，6： | 1 |
| 14 | Liver Stiffness Measurement Using Acoustic Radiation Force Impulse (ARFI) Elastography and Effect of Necroinflammation显示文摘 | Ki Tae Yoon Sun Min Lim Jun Yong Park Do Young Kim Sang Hoon Ahn Kwang-Hyub Han Chae Yoon Chon Mong Cho Jun Woo Lee Seung Up Kim | 2012 | Digestive Diseases and Sciences2012，，6： | 1 |
| 15 | Corrosion behaviour of sensitized AISI-type 316L stainless steel in molten carbonate fuel cell in cathode-gas environment显示文摘 | Kab Soo Lee Kyehyun Cho Tae Hoon Lim Seong-Ahn Hong Hwayong Kim | 1999 | Journal of Power Sources1999，，1： | 1 |
| 16 | Ethanol-induced DNA damage and repair-related molecules in human intestinalepithelial Caco-2 cells显示文摘 | Sung Chul Park Ji-Youn Lim Yoon Tae Jeen Bora Keum Yeon Seok Seo Yong Sik Kim Sung Joon Lee Hong Sik Lee Hoon Jai Chun Soon Ho Um Chang Duck Kim Ho Sang Ryu Donggeun Sul Eunha Oh | 2012 | Molecular Medicine Reports2012，，4： | 1 |
| 17 | miR‐206 regulates brain‐derived neurotrophic factor in Alzheimer disease model显示文摘 | Soon‐Tae Lee Kon Chu Keun‐Hwa Jung Jin Hee Kim Ji‐Young Huh Hyejin Yoon Dong‐Kyu Park Ji‐Yeon Lim Jeong‐Min Kim Daejong Jeon Hoon Ryu Sang Kun Lee Manho Kim Jae‐Kyu Roh | 2012 | Ann Neurol2012，，2： | 1 |
| 18 | Investigation of various ionomer-coated carbon supports for direct methanol fuel cell applications显示文摘 | Aulice M Scibioh Oh In Hwan Lim Tae Hoon | 2008 | Applied Catalysis B: Environmental2008，77，34： | 1 |
| 19 | Failure patterns correlate with the tumor response after preoperative chemoradiotherapy for locally advanced rectal cancer显示文摘 | Seok‐Byung Lim Chang Sik Yu Yong Sang Hong Tae Won Kim Jin‐Hong Park Jong Hoon Kim Jin Cheon Kim | 2012 | J. Surg. Oncol2012，，6： | 1 |
| 20 | The efficacy of frontline platinum-based combination chemotherapy in advanced adenocarcinoma of the ampulla of Vater显示文摘 | Seung Tae Kim Jeeyun Lee Kyu Taek Lee Jong Kyun Lee Kwang Hyuk Lee Seong-Ho Choi Jin-Seok Heo Dong Wook Choi Se Hoon Park Joon Oh Park Ho Yeong Lim Young Suk Park Won Ki Kang | 2010 | Medical Oncology2010，，4： | 1 |
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