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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 3 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 4 | Passive Immunization of Channel Catfish (Ictalurus punctatus) against the Ciliated Protozoan Parasite Ichthyophthirius multifiliis by Use of Murine Monoclonal Antibodies显示文摘 | Lin Tian-Long Clark T G Dickerson H W | 1996 | Infection and Immunity1996，64，10： | 2 |
| 5 | The gene for an abundant parasite coat protein predicts tandemly repetitive mental binding domains 显示文摘 | Clark T G Lin Tian-Long Jackwood D A | 1999 | Gene1999，229，： | 2 |
| 6 | Low-level chemical pretreatment for enhanced sludge solubilization显示文摘 | RAJAN R V LIN J G RAY B T | 1989 | Journal of Water Pollution Control Federation1989，61，： | 1 |
| 7 | Effect of brain e dema on infarct volume in a focal cerebral ischemia model in rats显示文摘 | Lin T N He Y Y Wu G Khan M Hsu C Y | 1993 | Stroke1993，24，： | 1 |
| 8 | Bidirectional cytokine interactions in the maternal-fetal relationship:is successful pregnancy a Th2 phenomenon显示文摘 | Wegmann T G Lin H Guilbert L | 1993 | Immunol Today1993，14，： | 1 |
| 9 | Bidirectional cytokine interactions in the maternal-fetal relationship:Is successful pregnancy a TH2 phenomenon?显示文摘 | Wegnumn T G Lin H Guilbert L | 1993 | Immunol Today1993，14，7： | 1 |
| 10 | Clay minerals from the Lichi Melange and its adjacent formations in the Coastal Range,eastern Taiwan显示文摘 | Lin S B Chen G T | | 0，，： | 1 |
| 11 | Hypothermia caused by slow and limited-volume fluid resuscitation decreases organ damage by hemorrhagic shock 显示文摘 | SUBEQ Y M HSU B G LIN N T | 2012 | Cytokine2012，60，1： | 1 |
| 12 | Study of W/HZSM-5-based catalysts for dehydro-aromatization of CH4 in absence of 02 (11):Action of promoters Zn and Li 显示文摘 | Xiong Z T Zhang H B Lin G D Zeng J L | 2001 | Catalysis Letters2001，74，34： | 1 |
| 13 | Multinational, double-blind,randomised, placebo-controlled, prospective study of esomeprazole inthe prevention of recurrent peptic ulcer in low-dose acetylsalicylicacid users: the LAVENDER study显示文摘 | Sugano K Choi M G Lin J T | 2014 | Gut2014，63，7： | 1 |
| 14 | Prevalence, isolation, and partial sequence analysis of hepatitis E virus from domestic animals in China 显示文摘 | Wang Y C Zhang H Y Xia N S Peng G Lan H Y Zhuang H Zhu Y H Li S W Tian K G Gu W J Lin W J Wu J X Li X Harrison T J | 2002 | Journal of Medical Virology2002，67，4： | 1 |
| 15 | Complexation of arsenate with humic sub- stance in water extract of compost显示文摘 | Lin H T Wang M C Li G C | 2004 | Chemsphere2004，56，11： | 1 |
| 16 | Low-level chemical pretreatment for enhanced sludge solubilization显示文摘 | Rajan R V Lin J G Ray B T | 1989 | Research Journal of the Water Pollution Control Federation1989，61，1112： | 1 |
| 17 | The effect of chemical treatment on reinforcement/matrix interaction in Kevlar-fiber/bismaleimide composites显示文摘 | Lin T K Wu S J Lai J G | 2000 | Composites Science and Technology2000，，： | 1 |
| 18 | Ku86 variant expression and function in multiple myeloma cells is associated with increased sensitivity to DNA damage 显示文摘 | Tai Y T Teoh G Lin B | 2000 | J Immunol2000，165，11： | 1 |
| 19 | A general cone beam reconstruction algorithm显示文摘 | WANG G LIN T H CHENG P C | 1993 | IEEE Trans on Medical Imaging1993，12，3： | 1 |
| 20 | Neural network based fuzzy logic control and decision system显示文摘 | Lin C T Lee C S G | 1991 | IEEE Transactions on Computers1991，40，12： | 1 |
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