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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 云南省农村地区男男性接触者与HIV相关的风险行为显示文摘目的探讨中国农村地区男男性接触者(MSM)与艾滋病病毒(HIV)相关的风险行为的具体特点和问题。方法采用半结构化深度访谈的方式进行定性研究。通过一个当地的MSM联系网络,以滚雪球和相互转告的方式招集了24名访谈对象。主要测量指标是与HIV有关的风险行为的上升情况。结果在中国农村地区,风险行为、社会歧视、独生子女政策以及传统中医的观念,在HIV的传播中都起着重要的作用。在中国,许多MSM过着双重生活;调查显示,安全套的使用情况也是因人而异,使风险行为'合理化'的意图是决定是否使用安全套的主要因素;就泌尿生殖系统的问题主动寻求医疗帮助的现象很不普遍,而现有卫生系统以及医务人员对此问题表现出来的不敏感,也进一步加剧了这种现象。结论在资源匮乏的农村地区,MSM人群存在着HIV流行的趋势,并有向普通人群传播的危险。 | 张建波 黄志威 T S K Kong D C Y Ling | 2007 | 中国艾滋病性病2007，13，5： | 3 |
| 3 | Pullulanase:role in starch hydrolysis and potential industrial applica-tions显示文摘 | Hii S L Tan J S Ling T C | 2012 | Enzyme Res2012，，： | 1 |
| 4 | A new HPV-DNA test for cervical-cancer screening in developing regions: a cross-sectional study of clinical accuracy in rural China显示文摘 | You-lin Qiao John W Sellors Paul S Eder Yan-ping Bao Jeanette M Lim Fang-hui Zhao Bernhard Weigl Wen-hua Zhang Roger B Peck Ling Li Feng Chen Qing-jing Pan Attila T Lorincz | 2008 | Lancet Oncology2008，，10： | 1 |
| 5 | Recognition of Grenvillian volcanic suite in the Shennongjia region and its tectonic significance for the South China Craton 显示文摘 | Qiu X F Ling W L Liu X M Kusky T Berkana W ZhangY H Gao Y J Lu S S Kuang H Liu C X | 2011 | Precambrian Research2011，191，： | 1 |
| 6 | Response of vegetative growth and fruit development to regulated deficit irrigation at different growth stages of pear- jujube tree 显示文摘 | Cui N B Du T S Ling T | 2009 | Agricultural Water Management2009，96，： | 1 |
| 7 | Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy显示文摘 | LoSasso T Chiu S Ling CC | 1998 | Med Phys1998，25，： | 1 |
| 8 | Comparative studies on moving force identification from bridge strains in laboratory显示文摘 | Chan T H T Yu Ling Law S S | 2000 | Journal of Sound and Vibration2000，235，1： | 1 |
| 9 | Effect of dietary HUFA on reproductive performance, tissue fatty acid profile and desaturase and elongase mRNAs in female swordtail Xiphophorus helleri 显示文摘 | Ling S Kuah M K TengkuMuhammad T S | 2006 | Aquaculture2006，，： | 1 |
| 10 | Seropolioside B inhibits IL - 113 and eytokines expression through NF-KB and inflamma- some NLRP3 pathways 显示文摘 | Zhu T Zhang L Ling S | 2014 | Mediators Inflamm2014，，： | 1 |
| 11 | Nuclear behaviour in the Basidiomycete,Vovariella volvacea显示文摘 | Chang S T Ling K Y | 1970 | American Journal of Botany1970，57，： | 1 |
| 12 | Interface Formation between the Al Electrode and Poly (PFT) Investigated in Situ by XPS显示文摘 | Ling Q D Li S Kang E T | 2002 | Applied Surface Science2002，199，： | 1 |
| 13 | Room occupancies:Cruise lines out-do the hotels显示文摘 | Toh R S Rivers M J Ling T W | | 0，，01： | 1 |
| 14 | Zp^k-1 -linear codes显示文摘 | Ling S Blackford J T | 2002 | IEEE Trans Inform Theory2002，48，： | 1 |
| 15 | Highly water- soluble magnetic nanopartieles as novel draw solutes in forward osmosis for water reuse显示文摘 | Ling Mingming Wang K Y Chung T S | 2010 | Ind Eng Chem Res2010，49，12： | 1 |
| 16 | Green fluorescent protein-tagged Edwardsiella tarda reveals portal of entry in fish显示文摘 | Ling S H M Wang X H Lim T M | 2001 | FEMS Microbiol Lett2001，194，2： | 1 |
| 17 | Seasonal trend of viral respiratory tract infections in the tropics显示文摘 | Chew F T Doraisingham S Ling A E | 1998 | Epidemiol Infect1998，121，： | 1 |
| 18 | Zpk+1-linear codes显示文摘 | LING S BLACKFORD J T | 2002 | IEEE Trans Inform Theory2002，48，10： | 1 |
| 19 | Total synthesis of a functional designer eukaryotic chromosome 显示文摘 | Annaluru N Muller H Mitchell L A Ramalingam S Stracquadanio G Richardson S M Dymond J S Kuang Z Scheifele L Z Cooper E M Cai Y Z Zeller K Agmon N Han J S Hadjithomas M Tullman J Caravelli K Cirelli K Guo Z Y London V Yeluru A Murugan S Kandavelou K Agier N Fischer G Yang K Martin J A Bilgel M Bohutski P Boulier K M Capaldo B J Chang J Charoen K Choi W J Deng P Dicarlo J E Doong J Dunn J Feinberg J I Fernandez C Floria C E Gladowski D Hadidi P Ishizuka I Jabbari J Lau C Y L Lee P A Li S Lin D Linder M E Ling J Liu J Liu J London M Ma H Mao J Mcdade J E Mcmillan A Moore A M Oh W C Ouyang Y Patel R Paul M Paulsen L C Qiu J Rhee A Rubashkin M G Soh I Y Sotuyo N E Srinivas V Suarez A Wong A Wong R Xie W R Xu Y J Yu A T Koszul R Bader J S Boeke J D Chandrasegaran S | 2014 | Science2014，344，6179： | 1 |
| 20 | Susceptibility to UV-A and UV-B provocation does not correlate with disease severity of polymorphic light eruption显示文摘 | Janssens AS Pavel S Ling T | 2007 | Arch Dermatol2007，143，5： | 1 |
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