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3篇 您的检索式:作者名="Lingling Lou"
    题名 作者 年代 出处 被引量
1Near-infrared chemiluminescent carbon nanogels for oncology imaging and therapy显示文摘Carbon nanogels(CNGs)with dual ability of reactive oxygen species(ROS)imaging and photodynamic therapy have been designed with selfassembled chemiluminescent carbonized polymer dots(CPDs).With efficient deep-red/near-infrared chemiluminescence(CL)emission and distinctive photodynamic capacity,the H2O2-driven chemiluminescent CNGs are further designed by assembling the polymeric conjugate and CL donors,enabling an in vitro and in vivo ROS bioimaging capability in animal inflammation models and a high-performance therapy for xenograft tumors.Mechanistically,ROS generated in inflammatory sites or tumor microenvironment can trigger the chemically initiated electron exchange luminescence in the chemical reaction of peroxalate and H2O2,enabling in vivo CL imaging.Meanwhile,part of the excited-state electrons will transfer to the ambient H2O or dissolved oxygen and in turn lead to the type I and type II photochemical ROS production of hydroxyl radicals or singlet oxygen,endowing the apoptosis of tumor cells and thus enabling cancer therapy.These results open up a new avenue for the design of multifunctional nanomaterials for bioimaging and antienoplastic agents.Chenglong Shen Tianci Jiang Qing Lou Wenbo Zhao Chaofan Lv Guangsong Zheng Hangrui Liu Pengfei Li Lingling Dai Kaikai Liu Jinhao Zang Feng Wang Lin Dong Songnan Qu Zhe Cheng Chongxin Shan 2022SmartMat2022,3,2:1
2A novel Zinc-finger- like gene from Tamarix hispida is involved in salt and osmotic toler- ance 显示文摘Yah An Yucheng Wang Lingling Lou 2011Journal of Plant Research2011,124,6:1
3FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt显示文摘Huadong Pei Liang Li Brooke L. Fridley Gregory D. Jenkins Krishna R. Kalari Wilma Lingle Gloria Petersen Zhenkun Lou Liewei Wang 2009Cancer Cell2009,,3:1
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