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8篇 您的检索式:作者名="Lingwei FAN"
    题名 作者 年代 出处 被引量
1Photothermal and pH dual-responsive self-healing coating for smart corrosion protection显示文摘A novel self-healing coating with photothermal and pH dual-responsive properties has been designed to protect carbon steel against corrosion by loading the stimuli-responsive microcapsules into a shape memory epoxy coating. The sandwich-like microcapsules were based on reduced graphene oxide/mesoporous silica(r GO@MS) assembled with a p H-responsive poly(N,N-dimethylaminoethyl methacrylate)(PDMAEMA) layer, and were loaded with benzotriazole(BTA) inhibitors(abbreviated as rGO@MS-P-BTA). Under near-infrared(NIR) light irradiation, the prominent photothermal effect of rGO could not only elevate the coating temperature to activate the shape memory effect and close the coating scratch, but also facilitate the release of corrosion inhibitors to suppress the corrosion activity. Moreover,the PDMAEMA as a p H-driven “gatekeeper” realized the controlled release of BTA from microcapsules at acid conditions. The surface morphology analysis, electrochemical impedance spectroscopy(EIS), and scanning electrochemical microscopy(SECM) were performed to evaluate the self-healing performance of the composite coatings. The results showed that the combination of NIR light and p H-responsive selfhealing effects endowed the coating with short healing time and prominent healing efficiency.Yao Huang Panjun Wang Weimin Tan Wenkui Hao Lingwei Ma Jinke Wang Tong Liu Fan Zhang Chenhao Ren Wei Liu Dawei Zhang 2022Journal of Materials Science & Technology2022,,12:2
2Outstanding Humidity Chemiresistors Based on Imine-Linked Covalent Organic Framework Films for Human Respiration Monitoring显示文摘Human metabolite moisture detection is important in health monitoring and non-invasive diagnosis.However,ultra-sensitive quantitative extraction of respiration information in real-time remains a great challenge.Herein,chemiresistors based on imine-linked covalent organic framework(COF)films with dual-active sites are fabricated to address this issue,which demonstrates an amplified humidity-sensing signal performance.By regulation of monomers and functional groups,these COF films can be pre-engineered to achieve high response,wide detection range,fast response,and recovery time.Under the condition of relative humidity ranging from 13 to 98%,the COFTAPB-DHTA film-based humidity sensor exhibits outstanding humidity sensing perfor-mance with an expanded response value of 390 times.Furthermore,the response values of the COF film-based sensor are highly linear to the relative humidity in the range below 60%,reflecting a quantitative sensing mechanism at the molecular level.Based on the dual-site adsorption of the(-C=N-)and(C-N)stretching vibrations,the revers-ible tautomerism induced by hydrogen bonding with water molecules is demonstrated to be the main intrinsic mechanism for this effective humidity detection.In addition,the synthesized COF films can be further exploited to effectively detect human nasal and oral breathing as well as fabric permeability,which will inspire novel designs for effective humidity-detection devices.Xiyu Chen Lingwei Kong Jaafar Abdul-Aziz Mehrez Chao Fan Wenjing Quan Yongwei Zhang Min Zeng Jianhua Yang Nantao Hu Yanjie Su Hao Wei Zhi Yang 2023Nano-Micro Letters2023,15,9:2
3Neuromorphic sensory computing显示文摘The number of sensory nodes in the Internet of everything continues to increase rapidly and generate massive data.The generated information from sensory nodes is much larger than the total collective human sensory throughput.It is quite challenging to send all of the data produced at sensory terminals to the“Cloud”computation center,especially for those time-delay sensitive applications.This situation demands a dramatic increase in the computation near or inside sensory networks.Inspired by biological sensory systems with a high data compression ratio,neuromorphic sensory computing provides a way to efficiently acquire and process a large volume of data from complex environments.Researchers have been investigating emerging materials,devices,circuits,and computing architectures to implement an artificial sensory system with high energy efficiency,speed,and density.Here we summarize the important features of biological systems and their hardware implementations.Electrons and photons are two representative information carriers,in which electron carrier allows high integration density for complex computing and photon carrier has high connectivity,high speed,wide bandwidth,and low power consumption.We overview the electronic and optical neuromorphic sensory computing and hybrid opto-electronic sensory computing,and present advances on multimodal sensory computing and their potential challenges.Tianqing WAN Sijie MA Fuyou LIAO Lingwei FAN Yang CHAI 2022Science China(Information Sciences)2022,65,4:2
4Construction of the 21st Century Maritime Silk Road:Present Situation,Opportunities,Problems and Solutions显示文摘The 21 st Century Maritime Silk Road is an important part of China's new landscape of all-round opening-up,responding to the joint demands of both China and many countries in Southeast Asia,South Asia and Africa.This paper examines countries and regions along the 21 st Century Maritime Silk Road and makes an in-depth study of their typical economic conditions,opportunities for cooperation with China,as well as related existing problems.There are opportunities in five areas for China to further cooperate with relevant countries and regions; industrial investment,infrastructure investment,resource development,overseas economic & trade zones and maritime economic development.There are also three outstanding problems; poor coordination among executive agents,insufficient financial support and lack of a sound and complete talent team.This paper offers several suggestions concerning the construction of the 21 st Century Maritime Silk Road to better fit the national conditions and joint demands of China and the countries and regions involved.He Fan Zhu He Zhang Qian Wu Lingwei(译) 2018Contemporary Social Sciences2018,3,3:1
5Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1^(high)CD11b^(+)cells elimination in hepatocellular carcinoma显示文摘Cryoablation(CRA)and microwave ablation(MWA)are two main local treatments for hepatocellular carcinoma(HCC).However,which one is more curative and suitable for combining with immunotherapy is still controversial.Herein,CRA induced higher tumoral PD-L1 expression and more T cells infiltration,but less PD-L1^(high)CD11b^(+)myeloid cells infiltration than MWA in HCC.Furthermore,CRA had better curative effect than MWA for anti-PD-L1 combination therapy in mouse models.Mechanistically,anti-PD-L1 antibody facilitated infiltration of CD8^(+)T cells by enhancing the secretion of CXCL9 from cDC1 cells after CRA therapy.On the other hand,anti-PD-L1 antibody promoted the infiltration of NK cells to eliminate PD-L1^(high)CD11b^(+)myeloid cells by antibody-dependent cell-mediated cytotoxicity(ADCC)effect after CRA therapy.Both aspects relieved the immunosuppressive microenvironment after CRA therapy.Notably,the wild-type PD-L1 Avelumab(Bavencio),compared to the mutant PD-L1 atezolizumab(Tecentriq),was better at inducing the ADCC effect to target PD-L1^(high)CD11b^(+)myeloid cells.Collectively,our study uncovered the novel insights that CRA showed superior curative effect than MWA in combining with anti-PD-L1 antibody by strengthening CTL/NK cell immune responses,which provided a strong rationale for combining CRA and PD-L1 blockade in the clinical treatment for HCC.Jizhou Tan Ting Liu Wenzhe Fan Jialiang Wei Bowen Zhu Yafang Liu Lingwei Liu Xiaokai Zhang Songling Chen Haibiao Lin Yuanqing Zhang Jiaping Li 2023Acta Pharmaceutica Sinica B2023,13,2:0
6Regulation of noncoding RNAs in innate lymphoid cells显示文摘Innate lymphoid cells(ILCs)have been defined in recent years and are important effector cells against pathogens and critical regulators in maintaining tissue homeostasis[1].Noncoding RNAs(ncRNAs),such as circular RNAs(circRNAs),long noncoding RNAs(lncRNAs),and microRNAs(miRNAs),in ILCs are emerging and have been described to function in ILC biology.These ncRNAs are distributed with unique patterns in ILCs and function in different molecular mechanisms.Accumulating research evidence demonstrates that ncRNA dysregulation links ILC-mediated immune responses and diseases.Benyu Liu Lingwei Zhang Pingping Zhu Zusen Fan 2023Cellular & Molecular Immunology2023,20,5:0
7Effect of soaking time of dithionite-citrate-bicarbonate solution on strength and deformation characteristics of lateritic soil显示文摘This study aimed to reveal the influence of different free-iron-oxides contents on the strength and deformation characteristics of in situ lateritic soil.A test method that combined the selective chemical dissolution method and in situ Ménard pressuremeter test(PMT)was proposed.The soaking time in dithioniteecitrateebicarbonate(DCB)solution was used as a variable to control the free-iron-oxides content in lateritic soil.Then,the in situ lateritic soil boreholes with different soaking time were tested by PMT.The results showed that the in situ horizontal pressure p0,critical edge pressure pf,ultimate pressure prediction pl,pressuremeter modulus Em,shear modulus Gm,and foundation-bearing capacity f0k of lateritic soil decreased rapidly after immersing in DCB solution within 1e4 d.With increasing soaking time,the decrease rate reduced gradually.Moreover,the relationship curve between free-iron-oxides content and soaking time declined rapidly and then stabilized,and the free-iron-oxides content at the inflection point was 30.11 g/kg.When the free-iron-oxides content changed to the inflection point,the free-iron-oxides that played a cementing role was largely removed,indicating that the effective cementing iron-content of Miaoling lateritic soil was about 52.9%.This study demonstrated that the proposed test method can determine the influence of free-iron-oxides content on the strength and deformation characteristics of lateritic soil.Wei Bai Wenbo Zhang Lingwei Kong Henghui Fan Aiguo Guo Guofang Xu 2023Journal of Rock Mechanics and Geotechnical Engineering2023,15,11:0
8Extensive sequence divergence between the reference genomes of Taraxacum kok-saghyz and Taraxacum mongolicum显示文摘Plants belonging to the genus Taraxacum are widespread all over the world,which contain rubber-producing and non-rubberproducing species.However,the genomic basis underlying natural rubber(NR)biosynthesis still needs more investigation.Here,we presented high-quality genome assemblies of rubber-producing T.kok-saghyz TK1151 and non-rubber-producing T.mongolicum TM5.Comparative analyses uncovered a large number of genetic variations,including inversions,translocations,presence/absence variations,as well as considerable protein divergences between the two species.Two gene duplication events were found in these two Taraxacum species,including one common ancestral whole-genome triplication and one subsequent round of gene amplification.In genomes of both TK1151 and TM5,we identified the genes encoding for each step in the NR biosynthesis pathway and found that the SRPP and CPT gene families have experienced a more obvious expansion in TK1151 compared to TM5.This study will have large-ranging implications for the mechanism of NR biosynthesis and genetic improvement of NR-producing crops.Tao Lin Xia Xu Huilong Du Xiuli Fan Qingwen Chen Chunyan Hai Zijian Zhou Xiao Su Liquan Kou Qiang Gao Lingwei Deng Jinsheng Jiang Hanli You Yihua Ma Zhukuan Cheng Guodong Wang Chengzhi Liang Guomin Zhang Hong Yu Jiayang Li 2022Science China(Life Sciences)2022,65,3:0
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