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| 1 | Fractional pyrolysis of Cyanobacteria from water blooms over HZSM-5 for high quality bio-oil production显示文摘Fractional pyrolysis and one-step pyrolysis of natural algae Cyanobacteria from Taihu Lake were comparatively studied from 200 to 500°C.One-step pyrolysis produced bio-oil with complex composition and low high heating value(HHV 30.9 MJ/kg). Fractional pyrolysis separated the degradation of different components in Cyanobacteria and improved the selectivity to products in bio-oil. That is, acids at 200°C, amides and acids at 300°C, phenols and nitriles at 400°C, and phenols at 500°C, were got as main products, respectively. HZSM-5 could promote the dehydration, cracking and aromatization of pyrolytic intermediates in fractional pyrolysis. At optimal HZSM-5 catalyst dosage of 1.0 g, the selectivity to products and the quality of bio-oil were improved obviously. The main products in bio-oil changed to nitriles(47.2%) at 300°C,indoles(51.3%) and phenols(36.3%) at 400°C. The oxygen content was reduced to 7.2 wt% and 9.4 wt%, and the HHV was raised to 38.1and 37.3 MJ/kg at 300 and 400°C, respectively. Fractional catalytic pyrolysis was proposed to be an efficient method not only to provide a potential solution for alleviating environmental pressure from water blooms, but also to improve the selectivity to products and obtain high quality bio-oil. | Huijuan Li Linling Li Rui Zhang Dongmei Tong Changwei Hu | 2014 | Journal of Energy Chemistry2014,23,6: | 3 |
| 2 | Enhanced desorption of PCB and trace metal elements (Pb and Cu) from contaminated soils by saponin and EDDS mixed solution显示文摘 | Menghua Cao Yuan Hu Qian Sun Linling Wang Jing Chen Xiaohua Lu | 2013 | Environmental Pollution2013,,: | 2 |
| 3 | Characteristics of alveolar macrophages in bronchioalveolar lavage fluids from active tuberculosis patients identified by single-cell RNA sequencing显示文摘Tuberculosis(TB),is an infectious disease caused by Mycobacterium tuberculosis(M.tuberculosis),and presents with high morbidity and mortality.Alveolar macrophages play an important role in TB pathogenesis although there is heterogeneity and functional plasticity.This study aimed to show the characteristics of alveolar macrophages from bronchioalveolar lavage fluid(BALF)in active TB patients.Single-cell RNA sequencing(scRNA-seq)was performed on BALF cells from three patients with active TB and additional scRNA-seq data from three healthy adults were established as controls.Transcriptional profiles were analyzed and compared by differential gene expression and functional enrichment analysis.We applied pseudo-temporal trajectory analysis to investigate correlations and heterogeneity within alveolar macrophage subclusters.Alveolar macrophages from active TB patients at the single-cell resolution are described.We found that TB patients have higher cellular percentages in five macrophage subclusters.Alveolar macrophage subclusters with increased percentages were involved in inflammatory signaling pathways as well as the basic macrophage functions.The TB-increased alveolar macrophage subclusters might be derived from M1-like polarization state,before switching to an M2-like polarization state with the development of M.tuberculosis infection.Cell-cell communications of alveolar macrophages also increased and enhanced in active TB patients.Overall,our study demonstrated the characteristics of alveolar macrophages from BALF in active TB patients by using scRNA-seq. | Qianqian Chen Chunmei Hu Wei Lu Tianxing Hang Yan Shao Cheng Chen Yanli Wang Nan Li Linling Jin Wei Wu Hong Wang Xiaoning Zeng Weiping Xie | 2022 | The Journal of Biomedical Research2022,36,3: | 1 |
| 4 | Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stageⅠ-Ⅲlung adenocarcinoma显示文摘The high risk of postoperative mortality in lung adenocarcinoma(LUAD)patients is principally driven by cancer recurrence and low response rates to adjuvant treatment.Here,A combined cohort containing 1,026 stageⅠ-Ⅲpatients was divided into the learning(n Z 678)and validation datasets(n Z 348).The former was used to establish a 16-mRNA risk signature for recurrence prediction with multiple statistical algorithms,which was verified in the valida-tion set.Univariate and multivariate analyses confirmed it as an independent indicator for both recurrence-free survival(RFS)and overall survival(OS).Distinct molecular characteristics between the two groups including genomic alterations,and hallmark pathways were compre-hensively analyzed.Remarkably,the classifier was tightly linked to immune infiltrations,high-lighting the critical role of immune surveillance in prolonging survival for LUAD.Moreover,the classifier was a valuable predictor for therapeutic responses in patients,and the low-risk group was more likely to yield clinical benefits from immunotherapy.A transcription factor regulato-ry proteineprotein interaction network(TF-PPI-network)was constructed via weighted gene co-expression network analysis(WGCNA)concerning the hub genes of the signature.The con-structed multidimensional nomogram dramatically increased the predictive accuracy.There-fore,our signature provides a forceful basis for individualized LUAD management with promising potential implications. | Yongqiang Zhang Zhao Yang Yuqin Tang Chengbin Guo Danni Lin d Linling Cheng Xun Hu Kang Zhang Gen Li | 2023 | Genes & Diseases2023,10,4: | 0 |
| 5 | Securing Patient-Centric Personal Health Records Sharing System in Cloud Computing显示文摘 | CHEN Danwei CHEN Linling FAN Xiaowei HE Liwen PAN Su Hu Ruoxiang | 2014 | China Communications2014,11,A01: | 0 |
| 6 | High frequency strong current tACS:a new dawn of non-drug therapy for patients with major depressive disorder显示文摘A commentary on:Transcranial alternating current stimulation for treating depression:a randomized controlled trial.By Wang H,Wang K,Xue Q,et al.Brain.2022;1451:83-91.doi:10.1093/brain/awab252.Major depressive disorder(MDD)is a common severe mental illness with recurring episodes.The most commonly used treatment is drug therapy,which is associated with a series of side effects and has an efficacy rate below 50%.1 Non-invasive brain stimulation technique has been gradually applied in clinical practice.Transcranial alternating current stimulation(tACS),a form of non-invasive brain stimulation,is a light,wearable piece of equipment for cortical stimulation.It modulates cortical excitability and spontaneous brain activity by applying an electric current to the scalp. | Linling Hu Xingxing Li Dongsheng Zhou Shaochang Wu | 2023 | General Psychiatry2023,36,6: | 0 |