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| 1 | Correlation between women's sub-health and reproductive diseases with pregnancies and labors显示文摘OBJECTIVE: To investigate whether female sub-health conditions and reproductive diseases areassociated with pregnancies and labors.METHODS: A cross-sectional survey was performed by using a structured questionnaire. A total of 1343 women aged 35 years or younger in six urban areas of Chengdu were included in the study.According to the Screening Criteria of sub-health conditions, these women were categorized into three groups: postpartum healthy group,sub-healthy group, and reproductive disease group. Data were double-entered using EpiData and the nanalyzed by SPSS.RESULTS: Pregnancy and labor were correlated with postpartum sub-health conditions. The number of pregnancies was negatively correlated with women's postnatal health but was positively correlated with the incidence of postpartum reproductive diseases.CONCLUSION: The number of pregnancies and labors is probably an important factor leading to sub-health conditions and the occurrence of reproductive diseases in women. Avoiding or reducing unwanted pregnancies and labors, enhancing the awareness of health among child bearing-age women are effective measures for preventing sub-health conditions. | Xiaojuan Xu Qian Zeng Hong Ding Lingyan Feng Linwen Deng | 2014 | Journal of Traditional Chinese Medicine2014，34，4： | 14 |
| 2 | Characterization of small RNAs from Ulva prolifera by high-throughput sequencing and bioinformatics analysis显示文摘The seaweed Ulva prolifera exists in 2 different states; attached to rocks or free-floating. However, there is little difference between the structures of the 2 states. U. prolifera thalli show significant differences in growth rate, with the attached thalli growing at a normal rate and free-floating thalli growing at a much faster rate. This raised the possibility that the growth of the two states may be regulated differently. miRNAs are important post-transcriptional regulators. In higher plants and animals, miRNAs have been extensively studied but they have been rarely studied in algae. To identify U. prolifera miRNAs and to investigate their possible roles in proliferation, we constructed and sequenced small RNA (sRNA) libraries from U. prolifera. Our results show that U. prolifera has a complex small RNA system that might play important roles in various processes. | HUANG AiYou WANG GuangCe HE LinWen NIU JianFeng ZHANG BaoYu | 2011 | Chinese Science Bulletin2011，56，27： | 3 |
| 3 | DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bd-2 inhibitors显示文摘Objective:Mcl-1 overexpression confers acquired resistance to Bcl-2 inhibitors in non-small cell lung cancer(NSCLC),but no direct Mcl-1 inhibitor is currently available for clinical use.Thus,novel therapeutic strategies are urgently needed to target Mcl-1 and sensitize the anti-NSCLC activity of Bcl-2 inhibitors.Methods:Cell proliferation was measured using sulforhodamine B and colony formation assays,and apoptosis was detected with Annexin V-FITC staining.Gene expression was manipulated using siRNAs and plasmids.Real-time PCR and Western blot were used to measure mRNA and protein levels.Immunoprecipitation and immunofluorescence were used to analyze co-localization o f dual specificity tyrosine-phosphorylation-regulated kinase 1A(DYRK1A)and Mcl-1.Results:Suppression of DYRK1A resulted in reduced Mcl-1 expression in NSCLC cells,whereas overexpression of DYRK1A significantly increased Mcl-1 expression.Suppression of DYRK1A did not alter Mcl-1 mRNA levels,but did result in an accelerated degradation o f Mcl-1 protein in NSCLC cells.Furthermore,DYRK1A mediated proteasome-dependent degradation o f Mcl-1 in NSCLC cells,and DYRK1A co-localized with Mcl-1 in NSCLC cells and was co-expressed with Mcl-1 in tumor samples from lung cancer patients,suggesting that Mcl-1 may be a novel DYRK1A substrate.We showed that combined therapy with harmine and Bcl-2 antagonists significantly inhibited cell proliferation and induced apoptosis in NSCLC cell lines as well as primary NSCLC cells.Conclusions:Mcl-1 is a novel DYRK1A substrate,and the role of DYRK1A in promoting Mcl-1 stability makes it an attractive target for decreasing Bcl-2 inhibitor resistance. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2020 | Cancer Biology & Medicine2020，17，2： | 2 |
| 4 | Numerical analysis of thermal striping induced high cycle thermal fatigue in a mixing tee显示文摘 | LEE J I HU Linwen SAHAP | 2009 | Nuclear Engineering and Design2009，239，5： | 1 |
| 5 | LES benchmark study of high cycle temperature fluctuations caused by thermal striping in a mixing tee显示文摘 | HU Linwen KAZIMI M S | 2006 | International Journal of Heat and Fluid Flow2006，27，1： | 1 |
| 6 | LES benchmark study of high cycle temperature fluctuations caused by thermal striping in a mixing tee显示文摘 | HU Linwen KAZIMI M S | 2006 | International Journal of Heat and Fluid Flow2006，27，1： | 1 |
| 7 | Simulation and optimization of a double THGEM detector显示文摘A double thick GEM (THGEM) detector with thin THGEM foils and small holes was constructed. In order to optimize the operation parameters of the detector, a simulation study of the detector was carried out using ANSYS and Garfield program. Some important characteristics, including primary electron transparency, avalanche development and the secondary electron loss were calculated. Parameters, such as electric field and gas choice were optimized. | WANG Xiaohu WEI Tao LONG Jidong LI Quanwei ZHANG Linwen | 2013 | Nuclear Science and Techniques2013，24，1： | 1 |
| 8 | 显示文摘 | Rea U Mekrell T Hu Linwen | 2009 | International Journal of Heat Transfer2009，52，78： | 1 |
| 9 | LES benchmark study of high cycle temperature fluctuations caused by thermal striping in a mixing tee显示文摘 | HU Linwen KAZIMI M S | 2006 | International Journal of Heat and Fluid Flow2006，27，1： | 1 |
| 10 | Comparative Analysis of MicroRNAs between Sporophyte and Gametophyte of Porphyra yezoensis显示文摘 | Linwen He Aiyou Huang Songdong Shen Jianfeng Niu Guangce Wang Paul Denny | 2012 | <journal-title>Comparative and Functional Genomics2012，，： | 1 |
| 11 | The approach to vertical U-shaped spreiten-burrow and Lower Devonian Pingyipu Formation nearshore- foreshore depositional environments Longmen Mountain Sichuan显示文摘 | LinWen—qiu(林文球) LiuZongwen(刘宗文) WangHong—feng(王洪峰) | 1986 | 矿物岩石1986，6，3： | 1 |
| 12 | Multifunctional interstitial-carbon-doped FeCoNiCu high entropy alloys with excellent electromagnetic-wave absorption performance显示文摘Electromagnetic-wave absorbing(EMA)materials that have efficient absorption performances,great me-chanical properties and chemical stability are rare and yet essential for communication security and pro-tection.Herein,flaky interstitial-carbon-doped FeCoNiCu high entropy alloys(HEAs)as novel EMA ma-terials were successfully prepared by high-energy ball-milling method.Interstitial-carbon doping as a modulating approach impacted the phase forming,morphology and electromagnetic properties of Fe-CoNiCu HEAs.Impedance matching was significantly optimized via tuning interstitial carbon contents.The carbon-doped FeCoNiCu HEAs with appropriate carbon contents delivered superior EMA performance compared with other HEAs EMA materials.Strong reflection loss as low as-61.1 dB in the Ku band,broad effective absorption bandwidth of 5.1 GHz was achieved for FeCoNiCuC_(0.04).Moreover,the carbon-doped FeCoNiCu HEAs exhibited excellent mechanical hardness and chemical stability.This work not only suggests that interstitial-carbon doping is an available approach to tuning electromagnetic properties of HEAs,but also presents carbon-doped FeCoNiCu HEAs as promising EMA materials for civilian and mili-tary due to the efficient absorption,broad bandwidth,great durability and stability. | Jianping Yang Linwen Jiang Zhonghao Liu Zhuo Tang Anhua Wu | 2022 | Journal of Materials Science & Technology2022，，18： | 1 |
| 13 | Experimental Investigation of Dielectric Barrier Discharge Using High Voltage Sub-microsecond Pulse Power in Atmospheric Air显示文摘An experimental device is used to study the characteristics of dielectric barrier discharge(DBD)plasma excited by high voltage sub-microsecond pulse power in atmospheric air.Glass,polytetrafluoroethene(PTFE)and plexiglass are used as dielectric barrier materials.Comparatively homogeneous discharge is obtained within 130 mm diameter area in atmospheric air using the three dielectric materials with gap distances of 4.5 mm,6.5 mm and 6.5 mm,respectively.There is no filamentary discharge observed by naked eyes or by camera with the exposure time of 0.25 s.Gas gap voltage,discharge current,discharge power density,etc.are calculated by using Liu’s equivalent circuit model for pulsed DBD.These parameters are used to study the DBD characteristics.Typically,current varies from tens of amperes to hundreds of amperes in atmospheric air DBD excited by sub-microsecond pulses.The peak power can reach to MW order of magnitude.The average power surface density of 1.0 W/cm2and the average electron density of 1011cm 3can also be obtained in the discharge.Rotational and vibrational temperatures,approximately 400 K and 2 650 K,respectively,are obtained by using the emission spectrum of the discharge.This is the basic work performed for a better understanding of the characteristics of atmospheric air DBD plasma excited by high voltage sub-microsecond pulsed power source. | LI Jie XIE Yutong DONG Pan MA Bing WANG Liming ZHANG Linwen | 2013 | 高电压技术2013，39，9： | 1 |
| 14 | Numerical analysis of thermal striping induced high cycle thermal fatigue in a mixing tee显示文摘 | Lee J 1 Hu Linwen Saha Pradip | 2009 | Nuclear Engineering and Design2009，239，5： | 1 |
| 15 | Bridgman growth of large aperture yttrium calcium oxyborate crystal显示文摘 | Wu Anhua Jiang Linwen Qian Guoxing | 2012 | Materials Research Bulletin2012，47，9： | 1 |
| 16 | Bacterial community composition in gut content and ambient sediment of two tropical wild sea cucumbers(Holothuria atra and H.leucospilota)显示文摘Sea cucumbers play an important role in sediment bioturbation in coral reef and rocky intertidal ecosystems,and bacteria were a commonly-reported component of holothuroid diets.Bacterial community composition in the foregut and hindgut of two common tropical sea cucumbers(Holothuria atra and H.leucospilota)and the ambient surface sediment were investigated using high throughput sequencing based on 16S rRNA gene analysis.A total of 5584 operational taxonomic units(OTUs)were obtained from 25 samples based on a 97%threshold,and more than half of the OTUs(n=3694,66.2%)were shared by the gut contents of two species of sea cucumbers and surrounding sediments.Bacterial richness and diversity in sediment samples were signifi cantly higher than those in the gut content samples(P<0.05).Proteobacteria was the predominant phylum in most samples showing 45.69%±8.61%,70.09%±4.03%,45.88%±5.38%,and 55.19%±0.79%reads in the foregut of H.leucospilota,hindgut of H.leucospilota,hindgut of H.atra,and sediment libraries,respectively,but Bacteroidetes was the predominant phylum with the relative content of 34.98%±5.52%in the foregut of H.atra.Among the dominant genera,reads related to the genera Anderseniella,Ilumatobacter,and Ruegeria were detected in all the gut contents and sediment libraries.A comparison of gut bacteria community between the two species of sea cucumbers suggested that H.atra had stronger feeding preference than H.leucospilota,and the same types of microbes escaped digestion of the two sea cucumber species.Obvious diff erent bacterial community composition in the foreguts of the two species of sea cucumbers and the surrounding sediments might result from the animal’s selective feeding for sediment patches.Bacterial community structure in hindgut contents of H.atra and H.leucospilota both diff ered clearly from adjacent sediments,which indicated feeding activity of deposit-feeding sea cucumbers could change the sedimental bacterial composition.In conclusion,from the perspective of bacteria,sea cucumber H.atra and H.leucospilota had diff erent feeding preferences,yet they could both aff ect bacterial composition in sediments by feeding activity.The motivation for selective feeding and sea cucumber-sediment interaction might be explored in the future. | Fei GAO Yue ZHANG Peilin WU Mengling CHEN Linwen HE Qiang XU Aimin WANG | 2022 | Journal of Oceanology and Limnology2022，40，1： | 0 |
| 17 | Erratum to DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bcl-2 inhibitors显示文摘In the published paper1,errors appeared in Figure 1D on page 391.In Figure 1D,an incorrect gel image was shown for Bcl-xL in NCI-H1299 cells.Figure 1D has been updated to correct the mistake above.The errors do not affect the conclusions of this article.We apologize for the errors and for any confusion that they may have caused. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2022 | Cancer Biology & Medicine2022，19，7： | 0 |
| 18 | Spectroscopic Diagnostics of Rotational Temperature in the Pulsed Atmospheric Air Plasma显示文摘Dielectric barrier discharge(DBD) attracts lots of attentions for its great application promises,and the rotational temperature is one of its mostly important parameters.In order to measure the rotational temperature of a pulsed DBD in atmospheric air,the temperature is studied by using optical emission spectroscopy(OES).The discharge is excited by a high voltage pulse with 124 ns rise time and 230 ns full width at half maximum(FWHM) at a repetition rate of a few hundred hertz.The rotational temperatures are studied using different voltages,different repetition rates of the pulse power supply,and different gaps between dielectrics: They are in the range from 390 K to 500 K during the whole discharge.When the gap between dielectrics increases,the rotational temperature initially decreases and then increases.The rotational temperature changes complexly when the pulse repetition rate changes.When the voltage increases,the rotational temperature always decreases,which is not expected.These results allow one to predict the rotational temperature at different supply power parameters and electrode configurations,which is useful for the DBD's industrial application. | DONG Pan LI Jie LI Xi XIE Yutong LONG Jidong ZHANG Linwen | 2013 | 高电压技术2013，39，10： | 0 |
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