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| 1 | Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease显示文摘BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)refers to any fatty liver disease that is not due to excessive use of alcohol.NAFLD probably results from abnormal hepatic lipid metabolism and insulin resistance.Aerobic exercise is shown to improve NAFLD.This review aimed to evaluate the molecular mechanisms involved in the beneficial effects of aerobic exercise on NAFLD.DATA SOURCE:We searched articles in English on the role of aerobic exercise in NAFLD therapy in Pub Med. | Rui Guo Emily C Liong Kwok Fai So Man-Lung Fung George L Tipoe | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，2： | 16 |
| 2 | Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges显示文摘BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver injury and mortality in Western countries and China. However, as to date, there is no direct and effective therapy for this disease. The aim of this review is to analyze the key progress and challenges of main current therapeutic approaches in NAFLD. DATA SOURCE: We carried out a PubMed search of English-language articles relevant to NAFLD therapy. RESULTS: There are two major therapeutic strategies for NAFLD treatment: (1) lifestyle interventions (including weight reduction, dietary modification and physical exercise) and (2) pharmaceutical therapies. Lifestyle interventions, particularly chronic and moderate intensity exercise, are the most effective and recognized clinical therapies for NAFLD. For pharmaceutical therapies, although their effects and mechanisms have been extensively investigated in laboratory studies, they still need further tests and investigations in clinical human trials. CONCLUSION: Future advancement of NAFLD therapy should focus on the mechanistic studies on cell based and animal models and human clinical trials of exercise, as well as the combination of lifestyle intervention and pharmaceutical therapy specifically targeting main signaling pathways related to lipid metabolism, oxidative stress and inflammation. | Jia Xiao Rui Guo Man Lung Fung Emily C Liong George L Tipoe | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，2： | 14 |
| 3 | 轻量型网片可以提高腹腔镜全腹膜外腹股沟疝修补术后的功能结局显示文摘前瞻性研究旨在比较腹腔镜全腹膜外腹股沟疝修补术(TEP)中,采用新型轻量型网片和传统重量型网片的差异,所有手术均在同一疝中心完成。方法自2004年11月到2005年7月,共有250例病人接受了腹腔镜TEP,采用轻量型(Ultrapro,30g/m)2或重量型网片(Prolene,100g/m2)。通过病历资料回顾及电话问卷调查获得随访数据。术后早期及远期均对病人进行随访,以评估术后结局的变化。结果 250例中有188例(75%)获得随访。在术后平均4个月及15个月进行的随访中发现,轻量型网片组和重量型网片组在疼痛或不适感的发生率及程度上没有差别。轻量型网片组在术后早期及远期对体力活动的影响显著小于重量型网片组,尤其是举重(9%vs.21%,平均随访4个月,Mann-WhitneyU,P=0.024)、行走(1%vs.11%,平均随访5个月,Mann-WhitneyU,P=0.006)及剧烈运动(7%vs.19%,平均随访15个月,Mann-Whitney-U,P=0.012)。腹股沟区的网片感或不适感两组差异无统计学意义。结论采用轻量型网片行腹腔镜TEP可以改善术后早期及远期的功能结局。轻量型网片可以显著减少对所有体力活动的影响。两者的疼痛都较轻微,表明腹腔镜手术的优势。 | Khan LR Liong S de Beaux AC Kumar S Nixon SJ | 2010 | 中国实用外科杂志2010，30，7： | 14 |
| 4 | Epidemiology of prostatitis: new evidence for a world-wide problem显示文摘 | John N. Krieger Donald E. Riley Phaik Yeong Cheah Men Long Liong Kah Hay Yuen | 2003 | World Journal of Urology2003，，2： | 3 |
| 5 | Balloon Dilation With Adequate Duration Is Safer Than Sphincterotomy for Extracting Bile Duct Stones: A Systematic Review and Meta-analyses显示文摘 | Wei–Chih Liao Yu–Kang Tu Ming–Shiang Wu Hsiu–Po Wang Jaw–Town Lin Joseph W. Leung Kuo–Liong Chien | 2012 | Clinical Gastroenterology and Hepatology2012，，10： | 2 |
| 6 | Optimization of growth of Lactobacillus acidophilns FTCC 0291 and evaluation of growth characteristics in soy whey medium: a response surface methodology approach显示文摘 | Fung WY Woo YP Liong MT | 2008 | J Agric Food Chem2008，56，17： | 1 |
| 7 | Multifunctional inorganic nanoparticles for imaging,targeting,and drug delivery显示文摘 | Liong M Lu J Kovochich M | 2008 | ACS Nano2008，2，5： | 1 |
| 8 | Terazosin therapy for chronic prostatitis/chronie pelvic pain syndrome: a randomized,'placebocontrolled trial显示文摘 | Cheah PY Liong ML Yuen KH | 2003 | Urol2003，169，2： | 1 |
| 9 | Bile salt de conjugation ability,bile salt hydrolase activity and cholesterol co-precipitation ability of lactobacilli strains显示文摘 | M T Liong N P Shah | 2005 | International Dairy Journal2005，15，： | 1 |
| 10 | Flood stage forecasting with support vector machines显示文摘 | Shie-Yui liong Chandrasekaran Sivapragasam | 2002 | Journal of the American Water Resources Association2002，38，1： | 1 |
| 11 | A systematic approach to noise reduction in observed chaotic time series显示文摘 | Sivakumar B Phoon K K Liong S Y | 1999 | Journal of Hydrology1999，219，34： | 1 |
| 12 | Safety of probiotics:Translocation and infection显示文摘 | Liong MT | 2008 | Nutr Rev2008，66，4： | 1 |
| 13 | Roles of Probiotics and Prebiotics in Colon Cancer Prevention:Postulated Mechanisms and In-vivo Evidence显示文摘 | Liong MT | 2008 | Int J Mol Sci2008，9，5： | 1 |
| 14 | Bile salt deconjugation ability of lactobacilli strains显示文摘 | Liong M T | 2005 | International Dairy Journal2005，，10： | 1 |
| 15 | Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties显示文摘 | XIA T KOVOCHICH M LIONG M | 2008 | ACS Nano2008，2，10： | 1 |
| 16 | Effects of a Lactobacillus casei Synbiotic on Serum Lipoprotein, Intestinal Microflora and Organic Acids in Rats 显示文摘 | LIONG M T SHAH N P | 2006 | Journal Dairy of Science2006，89，5： | 1 |
| 17 | Multifunctional inorganic nanoparticles for imaging,targeting,and drug delivery 显示文摘 | Liong M Lu J Kovochich M | 2008 | ACS Nano2008，2，5： | 1 |
| 18 | Bile salt deconjugation ability,bile salt hydrolase activity and cholesterol co-precipitation ability of lactobacilli strains显示文摘 | LIONG M T | | 0，，04： | 1 |
| 19 | Flood stage forecasting with SVM显示文摘 | LIONG S Y SIVAPRAGASM C | 2002 | Journal of the American Water Association2002，38，1： | 1 |
| 20 | Chronic prostatitis chronic pelvic pain syndrome: role of alpha blocker therapy显示文摘 | Lee S W Liong M L Yuen K H | 2007 | Urol Int2007，78，2： | 1 |
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