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| 1 | RESEARCH AND APPLICATION OF AS-CAST WEAR RESISTANCE HIGH CHROMIUM CAST IRON显示文摘RESEARCHANDAPPLICATIONOFASCASTWEARRESISTANCEHIGHCHROMIUMCASTIRONLiuJinhaiLiuGenshengLiGuoluHebeiUniversityofTechnologyWangKu... | Liu, Jinhai Liu, Gensheng Li, Guolu Wang, Kunjun Zeng, Daben | 1998 | Chinese Journal of Mechanical Engineering1998，11，2： | 6 |
| 2 | Integrated solid-state nanopore devices for third generation DNA sequencing显示文摘Third generation DNA sequencing relies on monitoring the ionic current blockage during the DNA molecule’s threading through a nanoscale pore.It is still really tough to attain the single base discrimination on a DNA strand by merely analyzing the ionic current due to speedy DNA translocation and low spatial resolution.More integrated configurations are pursued to present versatile comparative dissimilarities of the four bases by enhancing the spatial resolution within a DNA molecule translocation event,such as transverse tunneling current,local potential change,and capacitance oriented voltage resonance.In this mini review,the insight is provided into the status quo on several functionalized techniques and methodologies for DNA sequencing and furthermore concluding remark and outlook are presented. | WU GenSheng ZHANG Yin SI Wei SHA JingJie LIU Lei CHEN YunFei | 2014 | Science China(Technological Sciences)2014，57，10： | 4 |
| 3 | DNA sequencing technology based on nanopore sensors by theoretical calculations and simulations显示文摘DNA sequencing based on nanopore sensors is a promising tool for third-generation sequencing technology because of its special properties,such as revolutionized speed and low cost.With about two decades of nanopore technology development,the pioneering work has demonstrated the ability of nanopores to perform single-molecule detection and DNA sequencing.However,the microscopic mechanisms of DNA transport dynamics through nanopores remain largely unknown.Currently,DNA microscopic transport in a nanopore is difficult to characterize and several unexpected experimental observations are equivocal.This limitation can be resolved using theoretical calculations and simulations.These computational methods can monitor the entire dynamic process that DNA undergoes in solution at a single-atom resolution that can accurately unveil the mystery of DNA transport dynamics and predict certain unexpected phenomena.This paper mainly reports the recent applications of computational and simulation methods applied to the study of DNA transport through both biological and synthetic nanopores.We hope the theoretical calculations and simulations of DNA transport through nanopores can benefit the design of DNA sequencing devices. | Wei Si Yin Zhang Gensheng Wu Jingjie Sha Lei Liu Yunfei Chen | 2014 | Chinese Science Bulletin2014，59，35： | 3 |
| 4 | Temperature effect on translocation speed and capture rate of nanopore-based DNA detection显示文摘We study the effects of electrolyte temperature on DNA molecule translocation experimentally without and with a temperature gradient across nanopore membranes.The same temperatures on both electrolyte chambers are first considered.The DNA molecule translocation time is measured to be 2.44 ms at 2°C in both chambers,which is 1.57 times longer than at 20°C.Then the temperature difference effect is characterized in both chambers.The results show that the DNA translocation speed can be slowed down as long as one side temperature is lowered,irrespective of the temperature gradient direction.This indicates that the thermophoretic driving force generated by a temperature gradient has no obvious effect on the threading speed of DNA molecules,while the main reason for the slowed DNA translocation speed is the increased viscosity.Interestingly,the capture rate of DNA molecules is enhanced under a temperature gradient condition,and the capture rate during DNA translocation from hot side at 21°C to cold one at 2°C is 1.7 times larger than that under the condition of both chambers at 20°C.Finally,an optimized configuration is proposed to acquire higher capture rates and lower DNA translocation speeds. | ZHANGYin WU GenSheng MA Jian YUAN ZhiShan SI Wei LIU Lei SHA JingJie CHEN YunFei | 2015 | Science China(Technological Sciences)2015，58，3： | 2 |
| 5 | Throttle characteristics of multi-stage circumfluence nozzle during the separate-layer injection of CO_(2)显示文摘Separate-layer injection of CO2 is an important method to improve oil and gas production and recovery.Conventional single-stage nozzle is usually blocked by impurities,and the ice-barrier phenomenon is very common.To solve this problem,large-diameter multi-stage circumfluence nozzle was designed to release pressure stage by stage.In order to illuminate the throttle characteristics of the CO2 multi-stage circumfluence nozzles,numerical simulation was performed to test several nozzles with different diameters and stage numbers.Furthermore,we tested the throttle characteristics through laboratory experiments and obtained the effects of several critical parameters such as nozzle diameter,number of stage and pressure drop on the throttle characteristics.The results show that the flow rate decreases as the nozzle stage increases on the condition of constant pressure and nozzle diameter.And pressure difference increases as nozzle stage number increases under the constant flow rate.The throttle capability of multi-stage circumfluence nozzles was much better than the concentric nozzles.Large-diameter multi-stage nozzle is recommended rather than small-diameter single-stage nozzle during the process of separate-layer injection,which can efficiently prevent impurities and ice blocking.The results are expected to provide a theoretical support for the nozzle choice of separate-layer injection of CO2. | Haizhu Wang Gensheng Li Lichuan Zhao Youwen Wang Yun Liu Qingling Liu Meng Wang Fei Gao Meng Cai | 2018 | Petroleum2018，4，2： | 2 |
| 6 | Retarding and manipulating of DNA molecules translocation through nanopores显示文摘Nanopores are emerging sensitive sensors that can detect and analyze single charged molecule.Nanopores present a promising approach for sequencing human genome below US$1,000 because of its superior performance,such as high throughput and low cost.However,a dominant bottleneck,that is,the high translocation speed of DNA molecules,has to be overcome.This property decreases accuracy of nanopore sensors to the single-base level.In this review,we mainly introduce the recent research works of retarding and manipulating of DNA motion through nanopores by actively control of three forces,which are the driving force,interaction force between nanopore and molecule,and exterior drag force.Lastly,conclusion and further outlook are presented on future directions of nanopore-based DNA sequencing technology. | Yin Zhang Gensheng Wu Wei Si Jingjie Sha Lei Liu Yunfei Chen | 2014 | Chinese Science Bulletin2014，59，35： | 2 |
| 7 | Study of Effectof Hydraulic Perforating on Form Ation Fracturing Pressure 显示文摘 | Li Gensheng Liu Li Huang Zhongwei | 2006 | Journal of China University of Petroleum (Edition of NaturalScience)2006，30，5： | 1 |
| 8 | Linking supply chain management with mass customization capability 显示文摘 | Gensheng Liu George D Deitz | 2011 | International Journal of Physical Distribution & Logistics Management2011，41，7： | 1 |
| 9 | The role of mltogen-aetivated protein kinase phosphatase-1 in oxidative damage-lnduced cell dealth显示文摘 | Junying Zhou Yusen Liu Gensheng Wu | 2006 | Cancer Res2006，66，9： | 1 |
| 10 | SHP-2 Phosphatase Negatively Regulates the TRIF Adaptor Protein-Dependent Type I Interferon and Proinflammatory Cytokine Production显示文摘 | Huazhang An Wei Zhao Jin Hou Yan Zhang Yun Xie Yuejuan Zheng Hongmei Xu Cheng Qian Jun Zhou Yizhi Yu Shuxun Liu Gensheng Feng Xuetao Cao | 2006 | Immunity2006，，6： | 1 |
| 11 | Progress on research and mitigation of wind-blown sand risk in Dunhuang Singing Sand Mountain and Crescent Spring Scenic area,China显示文摘The Singing Sand Mountain and Crescent Spring Scenic Spot in Dunhuang,Northwest China is a world-renowned desert attraction that is also an integral component of the Dunhuang UNESCO Global Geopark.This scenic area underwent a 30-year transformation,i.e.,from a severe sand risk with spring water threatened by sand burial due to dune deformation,to restoration of the original sand flow field and mitigation of the sand burial problem.The current paper summarizes the research on the intensive monitoring of the dynamic change of star dunes near the spring,observation of wind and sand flow movement,and then restoring the harmonic vibration of the sand particles(singing sand)that were previously silenced.The existing and prospective impacts of anthropogenic and natural forces on the deformation of the sand dunes are investigated by integrated methods,guiding the implementation of mitigating measures with significant ameliorative effects.Contrast to common sand control practices that aim to reduce wind speed and stop blown sands,our research highlights the importance of maintaining the natural wind flow field in stabilizing surrounding dunes.These mitigation measures consist of removing excessive vegetation and newly constructed buildings to recover the original wind flow field and sand transport activity.Such research and mitigation efforts ensure the scientific protection and restoration of the special desert landform,and contribute to the mutual enhancement of the conservation and exploitation of this desert scenic spot and similar sites. | BenLi Liu KeCun Zhang JianJun Qu HaiJiang Li QingHe Niu ZhiShan An YingJun Pang LiHai Tan GenSheng Yang | 2023 | Research in Cold and Arid Regions2023，15，3： | 0 |
| 12 | Investigation on the interaction length and access resistance of a nanopore with an atomic force microscopy显示文摘Nanopore devices have attracted a lot of attention for their potential application in DNA sequencing. Here, we study how an occluding object placed near a nanopore affects its access resistance by integrating an atomic force microscopy with a nanopore sensor. It is found that there exists a critical hemisphere around the nanopore, inside which the tip of an atomic force microscopy will affect the ionic current. The radius of this hemisphere, which is a bit smaller than the theoretical capture radius of ions, increases linearly with the applied bias voltage and quadratically with the nanopore diameter, but is independent of the operation modes and scanning speeds of the atomic force microscopy. A theoretical model is also proposed to describe how the tip position and geometrical parameters affect the access resistance. | SI Wei YANG HaoJie LI Kun WU GenSheng ZHANG Yin KAN YaJing XIE Xiao SHA JingJie LIU Lei CHEN YunFei | 2017 | Science China(Technological Sciences)2017，60，4： | 0 |
| 13 | Preliminary Report on Species and Occurrence Regularity of Diseases,Pests and Weeds of Corn in Angola显示文摘[Objective]The paper was to understand species of diseases,pests and weeds and their occurrence periods and dynamic changes of quantity during corn growing period in rainy and dry seasons in Angola.[Method]Using systematic investigation method,the species and occurrence regularity of diseases,pests and weeds of corn in Pedras Negras farm(Malanje),Sanza Pombo farm(Uige)and Catete farm(Luanda)in the African continent,the Republic of Angola,were studied in two dry seasons and a rainy season from 2011 to 2012.[Result]The occurrence status of pests and diseases of corn during dry and rainy seasons were basically similar,and only individual diseases and pests had different incidence degrees.The corn varieties from the United States and Brazil had prominent advantages in resistance to diseases and barren.Due to different climate environments in dry and rainy seasons,the unearthed rate of weeds in fields was also different.Soil moisture had great impact on weed population and density.Soil layer depth greatly influenced unearthed speed and unearthed rate of weeds.[Conclusion]The study cleared species,occurrence period and harmful levels of pests,diseases and weeds of corn in three provinces of Angola. | Xue Gensheng Liu Bin Wang Lusheng Liu Jianhua Liu Dalu Yang Hui | 2013 | Plant Diseases and Pests2013，4，5： | 0 |
| 14 | Large-Scale Underground Storage of Renewable Energy Coupled with Power-to-X:Challenges,Trends,and Potentials in China显示文摘1.Introduction Promoting the green and low-carbon transition of energy systems and constructing a new renewable-dominated power system is essential to achieving carbon neutrality in China[1,2].Furthermore,implementing electrification and hydrogenation strategies to address energy consumption is necessary for a successful energy transition.China’s share of electricity in its total energy consumption is estimated to increase from 26%in 2021 to more than 70%by 2060. | Yachen Xie Jiashun Luo Zhengmeng Hou Gensheng Li Jianhua Liu Jianwei Tang Liangchao Huang Hans-Peter Beck Chunhe Yang | 2023 | Engineering2023，，10： | 0 |
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