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| 1 | Risk factors for ventilator-associated pneumonia among patients undergoing major oncological surgery for head and neck cancer显示文摘为头和颈癌症(SHNC ) 经历主要 oncological 外科的病人有医院的感染的特别地高的风险。我们试图在经历 SHNC 的病人为联系通风机的肺病(VAP ) 识别风险因素。学习包括了经历了在 2011 年 6 月和 2014 年 6 月之间的 SHNC 的 465 个病人。VAP,为 VAP 的风险因素,和 VAP 的生物方面的率回顾地被评估。VAP 的发生是 19.6%(n=95 ) 在要求了机械通风的超过 48 h 的病人。葡萄球菌(37.7%) , Enterobacteriaceae (32.1%) , Pseudomonas (20.8%) ,和 Haemophilus (16.9%) 是引起了 VAP 的主要细菌的种类。为 VAP 的独立风险因素被预付年龄,当前的吸烟地位,长期的妨碍的肺的疾病,和一个更高简化的尖锐生理学分数在承认之上的系统 II。Tracheostomy 是为 VAP 的一个独立保护的因素。在为确实开发了 VAP 的病人的 ICU 的停留的中部的长度是 8.0 和 6.5 天,分别地(P=0.006 ) 。在确实开发了 VAP 的病人之中的死亡是 16.8% 和 8.4% ,分别地(P < 0.001 ) 。因为通风的显著地扩大的持续时间, VAP 的潜在的经济影响高。一个预兆的回归模型与 95.3% 的敏感和 69.4% 的特性被开发。VAP 在并且谁正在经历 SHNC 的病人是普通的要求机械通风的超过 48 h。因此,创新预防措施应该在这张高风险的人口被开发并且适用。 | Yutao Liu Yaxia Di Shuai Fu | 2017 | Frontiers of Medicine2017，11，2： | 5 |
| 2 | Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial显示文摘We aimed to evaluate the effectiveness and safety of single-course initial regimens in patients with low-risk gestational trophoblastic neoplasia(GTN).In this trial (NCT01823315),276 patients were analyzed.Patients were allocated to three initiated regimens:single-course methotrexate(MTX),single-course MTX+dactinomycin(ACTD),and multi-course MTX(control arm).The primary endpoint was the complete remission(CR)rate by initial drug(s).The primary CR rate was 64.4%with multi-course MTX in the control arm.For the single-course MTX arm,the CR rate was 35.8%by one course;it increased to 59.3%after subsequent multi-course MTX,with non-inferiority to the control(difference-5.1%,95%confidence interval(CI)-19.4%to 9.2%,P=0.014).After further treatment with multi-course ACTD,the CR rate(93.3%)was similar to that of the control(95.2%,P=0.577).For the single-course MTX+ACTD arm,the CR rate was 46.7%by one course,which increased to 89.1%after subsequent multi-course,with non-inferiority(difference 24.7%,95%CI 12.8%-36.6%,P<0.001)to the control.It was similar to the CR rate by MTX and further ACTD in the control arm(89.1%vs.95.2%,P=0.135).Four patients experienced recurrence,with no death,during the 2-year follow-up.We demonstrated that chemotherapy initiation with single-course MTX may be an alternative regimen for patients with low-risk GTN. | Lili Chen Ling Xi Jie Jiang Rutie Yin Pengpeng Qu Xiuqin Li Xiaoyun Wan Yaxia Chen Dongxiao Hu Yuyan Mao Zimin Pan Xiaodong Cheng Xinyu Wang Qingli Li Danhui Weng Xi Zhang Hong Zhang Quanhong Ping Xiaomei Liu Xing Xie Beihua Kong Ding Ma Weiguo Lu | 2022 | Frontiers of Medicine2022，16，2： | 2 |
| 3 | Research on the nonuniformity correction of linear TDI CCD remote camera显示文摘 | Liu Yaxia Hao Zhihang | 2005 | Advanced Materials and Devices for Sensing and Imaging II Proceedings of SPIE2005，5633，： | 1 |
| 4 | Enhanced piezoelectric properties in low-temperature sintering PZN-PZT ceramics by adjusting Zr/Ti ratio显示文摘Pb_(0.96)Sr_(0.04)(Zr,Ti)_(0.7)(Zn_(1/3)Nb_(2/3))_(0.3)O_(3)(PZN-PZT)piezoceramics with various Zr/Ti ratios and Li_(2)CO_(3)sintering aid were sintered at 900°C by the solid-state reaction route.The samples with different Zr/Ti ratios were compared according to microstructure,phase structure,piezoelectricity,ferroelectricity,and dielectric relaxation.The Zr/Ti ratio in the PZN-PZT ceramics greatly affects the electrical properties.The Zr/Ti ratio affects the proportion between the rhombohedral and tetragonal phases and also affects the grain size.The PZN-PZT ceramics with the Zr/Ti ratio of 53:47 have the largest grain size and have optimized piezoelectric prop-erties(k_(p)=0.58,d_(33)=540 pC/N,and T_(C)=250°C).The larger the grain size,the lesser the grain boundary,the easier the domain wall motion,and the better the piezoelectric properties.The PZT ceramic with Zr/Ti ratio of 53:47 locates the morphotropic phase boundary(MPB)region which is one of the key factors for the high piezoelectric properties of the PZT. | Yaxia Luo Tao Pu Shibo Fan Hong Liu Jianguo Zhu | 2022 | Journal of Advanced Dielectrics2022，12，2： | 0 |
| 5 | Quantification of Aromatic Amino Acids in Cordyceps fungi by Micellar Electrokinetic Capillary Chromatography显示文摘A facile micellar electrokinetic chromatography(MEKC) method was developed for quantification of aromatic amino acids in Cordyceps fungi. The proposed MEKC method had linear calibration curves and detection limits at the μmol/L level. Contents of aromatic amino acids in Cordyceps were found in the range from 0.004 9 % to 0.028 0% for tryptophan(Trp), 0.036 6% to 0.078 1% for tyrosine(Tyr), and 0.029 1% to 0.136 2% for phenylalanine(Phe). Levels of amino acids in cultivated Cordyceps militaris were found higher than those in natural Cordyceps sinensis. Interestingly, the ratio of Tyr to its precursor, Phe, in C. sinensis(1.20 ± 0.091, n=3) was significantly higher than that in cultivated C. militaris(0.54 ± 0.170, n=3). This is likely because the enzyme-catalyzed in vivo biotransformation of Phe to Tyr is much more effective in natural C. sinensis, a biological hybrid of larva and parasitic fungus, than in cultivated C. militaris. | WEI Xin SU Yaxia HU Hankun LI Xiangtang XU Rui LIU Yiming | 2019 | Wuhan University Journal of Natural Sciences2019，24，3： | 0 |
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