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| 1 | Do anogenital gland secretionsof giant panda code for their sexual ability?显示文摘To test the hypothesis of whether ano- genital gland secretions (AGS) of giant panda code for their sexual ability, we collected AGS samples of 11 male (5 adult and 6 subadult) and 14 female (7 adult and 7 subadult) captive giant pandas (Ailuro- poda melanoleuca) from China Research and Con- servation Center for the Giant Panda at Wolong, Si- chuan, China from 1994 to 2002. The samples were analyzed by GC and GC-MS. The GC results showed that male and female pandas shared 20 constituents with equal capacity factors in the AGS. Further GC-MS analyses showed that there were a total of 95 compounds in the AGS. Nine constituents for the males and three for the females differed significantly in relative abundances between sexually active and inactive individuals, but no clear division between sexually active and inactive pandas by hierarchical cluster analyses on the relative abundances of a subset of 56 compounds. However, we were able to separate different age groups of male pandas by the constituents of AGS. 14 compounds were found sig- nificantly and negatively, and 8 compounds positively, correlated with pandas’ age by year. Our results suggest that the information contained in the AGS of panda might not code for pandas’ sexual ability but might for their age. These results will be valuable for captive breeding and conservation in the wild. | LIU Dingzhen YUAN Hong TIAN Hong WEI Rongping ZHANG Guiquan SUN Lixing WANG Liwen SUN Ruyong | 2006 | Chinese Science Bulletin2006，51，16： | 7 |
| 2 | Male panda (Ailuropoda melanoleuca) urine contains kinship information显示文摘Chemical communication plays an important role in kin selection and mate choice in mammals. The covariance of odor-genes of rodents has been documented and kinship odor has been proposed and termed, yet little is known of the relationship between genetic relatedness and chemical composition of kinship odors. Giant pandas (Ailuropoda melanoleuca) rely substantially on chemical communication to mediate their social interactions. To examine the relationship between genetic relatedness and compounds in the urine/anogenital gland secretions, we compared the similarities between genetic relatedness and the chemical profiles of anogenital gland secretions and urine via lineage construction and GC-MS (gas chromatography and mass spectrometry). We found that information about kinship odors was present only in the urine of male adults in the mating season but absent in the non-mating season. Adult females and all sub-adults did not have such kinship odors in either mating or non-mating season. Therefore, kinship odor in the panda was contingent on age, sex, and season. This is the first report about the condition-dependent expression of kinship odor, which may have a sig- nificant implication in the practice of panda conservation in relation to chemical communication and sexual selection. | LIU DingZhen WEI RongPing ZHANG GuiQuan YUAN Hong WANG ZhiPeng SUN Lixing ZHANG Jianxu ZHANG HeMin | 2008 | Chinese Science Bulletin2008，53，18： | 6 |
| 3 | RNAi-mediated suppression of the abscisic acid catabolism gene Os ABA8ox1 increases abscisic acid content and tolerance to saline–alkaline stress in rice(Oryza sativa L.)显示文摘Saline–alkaline(SA) stress is characterized by high salinity and high alkalinity(high p H), which severely inhibit plant growth and cause huge losses in crop yields worldwide. Here we show that a moderate elevation of endogenous abscisic acid(ABA) levels by RNAi-mediated suppression of Os ABA8 ox1(Os ABA8 ox1-kd), a key ABA catabolic gene, significantly increased tolerance to SA stress in rice plants. We produced Os ABA8 ox1-kd lines in two different japonica cultivars, Dongdao 4 and Nipponbare. Compared with nontransgenic control plants(WT), the Os ABA8 ox1-kd seedlings accumulated 25.9%–55.7% higher levels of endogenous ABA and exhibited reduced plasmalemma injury, ROS accumulation and Na;/K;ratio, and higher survival rates, under hydroponic alkaline conditions simulated by 10, 15, and 20 mmol L-1 of Na;CO;. In pot trials using SA field soils of different alkali levels(p H 7.59, 8.86, and 9.29), Os ABA8 ox1–kd plants showed markedly higher seedling survival rates and more vigorous plant growth, resulting in significantly higher yield components including panicle number(85.7%–128.6%), spikelets per panicle(36.9%–61.9%), branches(153.9%–236.7%), 1000–kernel weight(20.0%–28.6%), and percentage of filled spikelets(96.6%–1340.8%) at harvest time. Under severe SA soil conditions(p H = 9.29, EC = 834.4 μS cm-1),Os ABA8 ox1-kd lines showed an 194.5%–1090.8% increase in grain yield per plant relative to WT plants.These results suggest that suppression of Os ABA8 ox1 to increase endogenous ABA levels provides a new molecular approach for improving rice yield in SA paddies. | Xiaolong Liu Xianzhi Xie Chongke Zheng Lixing Wei Xiaowei Li Yangyang Jin Guohui Zhang Chang-Jie Jiang Zhengwei Liang | 2022 | The Crop Journal2022，10，2： | 3 |
| 4 | Experimental Gaussian Boson sampling显示文摘Gaussian Boson sampling(GBS) provides a highly efficient approach to make use of squeezed states from parametric down-conversion to solve a classically hard-to-solve sampling problem. The GBS protocol not only significantly enhances the photon generation probability, compared to standard Boson sampling with single photon Fock states, but also links to potential applications such as dense subgraph problems and molecular vibronic spectra. Here, we report the first experimental demonstration of GBS using squeezed-state sources with simultaneously high photon indistinguishability and collection efficiency.We implement and validate 3-, 4- and 5-photon GBS with high sampling rates of 832, 163 and 23 kHz,respectively, which is more than 4.4, 12.0, and 29.5 times faster than the previous experiments.Further, we observe a quantum speed-up on a NP-hard optimization problem when comparing with simulated thermal sampler and uniform sampler. | Han-Sen Zhong Li-Chao Peng Yuan Li Yi Hu Wei Li Jian Qin Dian Wu Weijun Zhang Hao Li Lu Zhang Zhen Wang Lixing You Xiao Jiang Li Li Nai-Le Liu Jonathan P.Dowling Chao-Yang Lu Jian-Wei Pan | 2019 | Science Bulletin2019，64，8： | 3 |
| 5 | PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway显示文摘Our previous studies have showed that C-C motif chemokine ligand 20(CCL20)advanced tumor progression and enhanced the chemoresistance of cancer cells by positively regulating breast cancer stem cell(BCSC)self-renewal.However,it is unclear whether CCL20 affects breast cancer progression by remodeling the tumor microenvironment(TME).Here,we observed that polymorphonuclear myeloid-derived suppressor cells(PMN-MDSCs)were remarkably enriched in TME of CCL20-overexpressing cancer cell orthotopic allograft tumors.Mechanistically,CCL20 activated the differentiation of granulocyte-monocyte progenitors(GMPs)via its receptor C-C motif chemokine receptor 6(CCR6)leading to the PMN-MDSC expansion.PMN-MDSCs from CCL20-overexpressing cell orthotopic allograft tumors(CCL20-modulated PMN-MDSCs)secreted amounts of C-X-C motif chemokine ligand 2(CXCL2)and increased ALDH+BCSCs via activating CXCR2/NOTCH1/HEY1 signaling pathway.Furthermore,C-X-C motif chemokine receptor 2(CXCR2)antagonist SB225002 enhanced the docetaxel(DTX)effects on tumor growth by decreasing BCSCs in CCL20high-expressing tumors.These findings elucidated how CCL20 modulated the TME to promote cancer development,indicating a new therapeutic strategy by interfering with the interaction between PMN-MDSCs and BCSCs in breast cancer,especially in CCL20high-expressing breast cancer. | Rui Zhang Mengxue Dong Juchuanli Tu Fengkai Li Qiaodan Deng Jiahui Xu Xueyan He Jiajun Ding Jie Xia Dandan Sheng Zhaoxia Chang Wei Ma Haonan Dong Yi Zhang Lixing Zhang Lu Zhang Suling Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 6 | Red and processed meat intake and risk of breast cancer:a meta-analysis of prospective studies显示文摘 | GUO Jingyu WEI Wei ZHAN Lixing | 2015 | Breast Cancer Res Treat2015，151，： | 1 |
| 7 | Preservation of Mitochondrial Structure and Function After Cardioplegic Arrest in the Neonate Using a Selective Mitochondrial K ATP Channel Opener显示文摘 | Lixing Wang Caroline Kinnear James M. Hammel Wei Zhu Zhongdong Hua Wenyu Mi Christopher A. Caldarone | 2006 | The Annals of Thoracic Surgery2006，，5： | 1 |
| 8 | Identification and validation of rice reference proteins for western blotting显示文摘 | LiX M Bai H Wang X Y Li L Y Cao Y H Wei J Liu Y M Liu L J Gong X D Wu L Liu S Q Liu G Z | 2011 | Journal of Experimental Botany2011，62，14： | 1 |
| 9 | Dynamic response of func- tional virtual prototyping of motorcycle under combined excitations 显示文摘 | Sun Lixing Shu Gequn Wei Haiqiao | 2010 | Powder Technology2010，191，1： | 1 |
| 10 | Q-switched Yb Doped Fiber RingLaser with a M-Z Interferometer显示文摘 | XU Lixing MING Hai AN Wei ZHANG Xiaosi Etc | 2000 | CHINESE JOURNAL OF LASERS2000，9，5： | 1 |
| 11 | Evaluation of maize root growth and genome-wide association studies of root traits in response to low nitrogen supply at seedling emergence显示文摘Nitrogen(N) deficiency is one of the main factors limiting maize(Zea mays L.) productivity. Genetic improvement of root traits could improve nitrogen use efficiency. An association panel of 461 maize inbred lines was assayed for root growth at seedling emergence under high-nitrate(HN, 5 mmol L^(-1))and low-nitrate(LN, 0.05 mmol L^(-1)) conditions. Twenty-one root traits and three shoot traits were measured. Under LN conditions, the root-to-shoot ratio, root dry weight, total root length, axial root length,and lateral root length on the primary root were all increased. Under LN conditions, the heritability of the plant traits ranged from 0.43 to 0.82, a range much wider than that of 0.27 to 0.55 observed under HN conditions. The panel was genotyped with 542,796 high-density single-nucleotide polymorphism(SNP) markers. Totally 328 significant SNP markers were identified using either mixed linear model(MLM) or general linear model analysis, with 34 detected by both methods. In the 100-kb intervals flanking these SNP markers, four candidate genes were identified. Under LN conditions, the protoporphyrinogen IX oxidase 2 gene was associated with total root surface area and the DELLA protein-encoding gene was associated with the length of the visible lateral root zone of the primary root. Under HN conditions, a histone deacetylase gene was associated with plant height. Under both LN and HN conditions, the gene encoding MA3 domain-containing protein was associated with the first whorl crown root number. The phenotypic and genetic information from this study may be exploited for genetic improvement of root traits aimed at increasing NUE in maize. | Xichao Sun Wei Ren Peng Wang Fanjun Chen Lixing Yuan Qingchun Pan Guohua Mi | 2021 | The Crop Journal2021，9，4： | 1 |
| 12 | Effect of Wuda granule on gastrointestinal function recovery after laparoscopic intestinal resection:a randomized–controlled trial显示文摘Background Previous studies have suggested that the Wuda granule(WDG)could promote the recovery of gastrointestinal(GI)function after gynecologic abdominal surgery.This trial aimed to investigate the efficacy and safety of WDG in the rapid recovery of GI function in patients after laparoscopic intestinal resection in the setting of enhanced recovery after surgery(ERAS)-based perioperative care.Methods We performed a randomized,double-blind,placebo-controlled pilot trial.Thirty patients who met the inclusion criteria were randomly assigned to either the WDG group or the placebo group in a 1:1 ratio.The patients received WDG or placebo twice a day in addition to ERAS-based perioperative care,starting on post-operative Day 1 until Day 3.The primary outcomes were time to first bowel movement and time to first tolerance of solid food.The secondary outcomes were time to first flatus,length of hospital stay(LOS),and post-operative ileus-related morbidity.Adverse events were also recorded.Results There were no statistically significant differences in baseline characteristics between the two groups.The median time to first bowel movement was significantly decreased in the WDG group compared with the control group(27.6 vs 50.1 h;P<0.001),but the median times to first flatus(22.9 vs 25.1 h;P>0.05)and LOS(5.0 vs 5.0 days;P>0.05)were not statistically different.The occurrence rates of post-operative nausea,vomiting,abdominal distension,and abdominal pain were similar in the two groups.No adverse events occurred in any patients.Conclusions The addition of WDG to ERAS post-operative care after laparoscopic intestinal resection can safely promote the rapid recovery of GI function. | Haiping Zeng Wei Wang Lixing Cao Yuyan Wu Wenwei Ouyang Dechang Diao Jin Wan Qicheng Chen Zhiqiang Chen | 2022 | Gastroenterology Report2022，10，1： | 1 |
| 13 | Rheological behavior of lubricating systems in polypropylene/seaweed composites 显示文摘 | Lixing Luan Wei Wu Manfred H Wagner | 2011 | Journal of Applied Polymer Science2011，121，4： | 1 |
| 14 | Effect of place ment angle on the stability of loaded titanium microscrews: A microeomputed tomographic and biomechanieal analysis显示文摘 | Lixing Zhao Zhenrui Xu Xing Wei | 2011 | Am J Orthod Dentofaeial Orthop2011，139，： | 1 |
| 15 | The effect of varying healing times on orthodontic mini-implant stability: a microscopic computerized tomographic and biomechanical analysis显示文摘 | Qiang Zhang Lixing Zhao Yeke Wu Hui Wang Zhihe Zhao Zhenrui Xu Xing Wei Tian Tang | 2011 | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology2011，，4： | 1 |
| 16 | Photon-counting distributed free-space spectroscopy显示文摘Spectroscopy is a well-established nonintrusive tool that has played an important role in identifying and quantifying substances,from quantum descriptions to chemical and biomedical diagnostics.Challenges exist in accurate spectrum analysis in free space,which hinders us from understanding the composition of multiple gases and the chemical processes in the atmosphere.A photon-counting distributed free-space spectroscopy is proposed and demonstrated using lidar technique,incorporating a comb-referenced frequency-scanning laser and a superconducting nanowire single-photon detector.It is suitable for remote spectrum analysis with a range resolution over a wide band.As an example,a continuous field experiment is carried out over 72 h to obtain the spectra of carbon dioxide(CO_(2))and semi-heavy water(HDO,isotopic water vapor)in 6 km,with a range resolution of 60 m and a time resolution of 10 min.Compared to the methods that obtain only column-integrated spectra over kilometer-scale,the range resolution is improved by 2-3 orders of magnitude in this work.The CO_(2)and HDO concentrations are retrieved from the spectra acquired with uncertainties as low as±1.2%and±14.3%,respectively.This method holds much promise for increasing knowledge of atmospheric environment and chemistry researches,especially in terms of the evolution of complex molecular spectra in open areas. | Saifen Yu Zhen Zhang Haiyun Xia Xiankang Dou Tengfei Wu Yihua Hu Manyi Li Mingjia Shangguan Tianwen Wei Lijie Zhao Lu Wang Pu Jiang Chengjun Zhang Lixing You Leigang Tao Jiawei Qiu | 2021 | Light(Science & Applications)2021，10，11： | 1 |
| 17 | Solar Cells and LightSensors Based on Nanoparticle - Grafted CarbonNanotube Films 显示文摘 | LIX L’JIA Y’WEI J Q | 2010 | ACS Nano2010，4，： | 1 |
| 18 | Potential Chemosignals in the Anogenital Gland Secretion of Giant Pandas, Ailuropoda melanoleuca, Associated with Sex and Individual Identity显示文摘 | Jian-Xu Zhang Dingzhen Liu Lixing Sun Rongping Wei Guiquan Zhang Honglin Wu Hemin Zhang Chenghua Zhao | 2008 | Journal of Chemical Ecology2008，，3： | 1 |
| 19 | A combined p-value test for the mean difference of high-dimensional data显示文摘This paper proposes a novel method for testing the equality of high-dimensional means using a multiple hypothesis test. The proposed method is based on the maximum of standardized partial sums of logarithmic p-values statistic. Numerical studies show that the method performs well for both normal and non-normal data and has a good power performance under both dense and sparse alternative hypotheses. For illustration, a real data analysis is implemented. | Wei Yu Wangli Xu Lixing Zhu | 2019 | Science China Mathematics2019，62，5： | 0 |
| 20 | Intranasal glial heterotopia in an infant boy显示文摘Introduction:Nasal glial heterotopia is a rare congenital developmental disorder characterized by meningeal epithelium and/or glial components.Case presentation:A 2-month-old boy presented for treatment of a congenital mass in the right nasal cavity near the pharynx.The preoperative diagnosis was congenital intranasal neoplasm.Nasal endoscopic resection of the nasopharyngeal mass was performed under general anesthesia.Histological findings in the resected tissue supported a diagnosis of intranasal glial heterotopia.The surgical outcome was good and no surgical site infection occurred.During 1 year of follow-up,the patient did not exhibit recurrence of heterotopia or related symptoms.Conclusion:Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia.Thorough preoperative imaging should be performed before glioma resection.The mass should be differentiated from encephalocele to prevent cerebrospinal fluid leakage and meningitis. | Wei Zhang Lixing Tang Wentong Ge | 2021 | Pediatric Investigation2021，5，1： | 0 |
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