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| 1 | Micro-structural evolution and their effects on physical properties in different types of tectonically deformed coals显示文摘The macromolecular structure of tectonically deformed coals(TDC)may be determined by the deformation mechanisms of coal.Alterations of the macromolecular structure change the pore structure of TDC and thereby impact physical properties such as porosity and permeability.This study focuses on structure and properties of TDC from the Huaibei and Huainan coal mining areas of southern North China.Relationships between the macromolecular structure and the pore structure of TDC were analyzed using techniques such as X-ray diffraction,high-resolution transmission electron microcopy,and the low-temperature nitrogen adsorption.The results indicated that the directional stress condition can cause the arrangement of basic structural units(BSU)more serious and closer.And,the orientation is stronger in ductile deformed coal than in brittle deformed coal.Tectonic deformation directly influences the macromolecular structure of coal and consequently results in dynamic metamorphism.Because the size of BSU in brittle deformed coal increases more slowly than in ductile deformed coal,frictional heating and stress-chemistry of shearing areas might play a more important role,locally altering coal structure under stress,in brittle deformed coal.Strain energy is more significant in increasing the ductile deformation of coal.Furthermore,mesopores account for larger percentage of the nano-scale pore volume in brittle deformed coals,while mesopores volume in ductile deformed coal diminishes rapidly along with an increase in the proportion of micropores and sub-micropores.This research also approved that the deformations of macromolecular structures change nano-scale pore structures,which are very important for gas adsorption and pervasion space for gas.Therefore,the exploration and development potential of coal bed methane is promising for reservoirs that are subjected to a certain degree of brittle deformation(such as schistose structure coal,mortar structure coal and cataclastic structure coal).It also holds promise for TDC resulting from wrinkle structure coal of low ductile deformation and later superimposed by brittle deformation.Other kinds of TDC suffering from strong brittle-ductile and ductile deformation,such as scale structure coal and mylonitic structure coal,are difficult problems to resolve. | Yiwen Ju Kray Luxbacher Xiaoshi Li Guochang Wang Zhifeng Yan Mingming Wei Liye Yu | 2014 | International Journal of Coal Science & Technology2014，1，3： | 43 |
| 2 | The effect of different deformation mechanisms on the chemical structure of anthracite coals显示文摘To study the effect of different deformation mechanisms on the chemical structure of anthracite coals and further understand the correlation between changed chemical structures and coal and gas outburst, ten groups of sub-high-temperature and sub-high-pressure deformation experiments were performed. All samples maintained primary structure, which were collected from the Qudi Mine in the southern Qinshui Basin of China. The samples were analyzed by ultimate analysis, Vitrinite Reflection(VR), Fourier Transform Infrared spectroscopy(FTIR), and Raman spectroscopy both before and after deformation experiments for contrasting. The results showed that the VR values of all samples after experiments were significantly higher than before experiments, which suggested that the metamorphism degree of anthracite coals was increased by deformation. The results also indicated that both temperature and strain rate had significant effects on the chemical structure of anthracite coals. At a high strain rate of 4×10?5 s?1, the deformation of the samples was mainly brittle in which the mechanical energy was transformed mainly into frictional energy. In this situation, all samples developed several distinct fractured surfaces and the change of chemical structures was not obvious. On the contrary, with the decrease of the strain rates, the ductile deformation was dominated and the mechanical energy was mainly transformed into strain energy, resulting in the accumulation of deformation energy confessed by increasing quantity of dislocation and creep in the coal's interior nucleus. The absorption in the aromatic ring groups increased; otherwise the absorption in the aliphatic structures and ether oxygen groups decreased rapidly. During these experiments, CO was collected from two experimental samples. The number of aromatic rings and the structure defects within the two generated gas samples increased and the degree of molecular structure orders decreased. | XU RongTing LI HuiJun HOU QuanLin LI XiaoShi YU LiYe | 2015 | Science China Earth Sciences2015，58，4： | 4 |
| 3 | Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis显示文摘Objective:This study aimed to examine(1)the independent effects of hypoxia on cognitive function and(2)the effects of exercise on cognition while under hypoxia.Methods:Design:Systematic review with meta-analysis.Data sources:PubMed,Scopus,Web of Science,PsychInfo,and SPORTDiscus were searched.Eligibility criteria for selecting studies:randomized controlled trials and nonrandomized controlled studies that investigated the effects of chronic or acute exercise on cognition under hypoxia were considered(Aim 2),as were studies investigating the effects of hypoxia on cognition(Aim 1).Results:In total,18 studies met our inclusionary criteria for the systematic review,and 12 studies were meta-analyzed.Exposure to hypoxia impaired attentional ability(standardized mean difference(SMD)=-0.4),executive function(SMD=-0.18),and memory function(SMD=-0.26),but not information processing(SMD=0.27).Aggregated results indicated that performing exercise under a hypoxia setting had a significant effect on cognitive improvement(SMD=0.3,95%confidence interval:0.14-0.45,I^2=54%,p<0.001).Various characteristics(e.g.,age,cognitive task type,exercise type,exercise intensity,training type,and hypoxia level)moderated the effects of hypoxia and exercise on cognitive function.Conclusion:Exercise during exposure to hypoxia improves cognitive function.This association appears to be moderated by individual and exercise/hypoxia-related characteristics. | Myungjin Jung Liye Zou Jane Jie Yu Seungho Ryu Zhaowei Kong Lin Yang Minsoo Kang Jingyuan Lin Hong Li Lee Smith Paul D.Loprinzi | 2020 | Journal of Sport and Health Science2020，9，6： | 3 |
| 4 | Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy显示文摘 | Yifang Han Hui Cai Liye Ma Yibo Ding Xiaojie Tan Wenjun Chang Wei Guan Yan Liu Qiuxia Shen Yongwei Yu Hongwei Zhang Guangwen Cao | 2013 | Cancer2013，，19： | 2 |
| 5 | Safety,tolerability,and pharmacokinetics of BAT8001 in patients with HER2-positive breast cancer:An open-label,dose-escalation,phase I study显示文摘Background:The introductions of anti-human epidermal growth factor receptor-2(HER2)agents have significantly improved the treatment outcome of patients with HER2-positive breast cancer.BAT8001 is a novel antibodydrug conjugate targeting human epidermal growth factor receptor-2(HER2)-expressing cells composed of a trastuzumab biosimilar linked to the drug-linker Batansine.This dose-escalation,phase I study was designed to assess the safety,tolerability,pharmacokinetics,and preliminary anti-tumor activity of BAT8001 in patients with HER2-positive locally advanced or metastatic breast cancer.Methods:This trial was conducted in subjects with histologically confirmed HER2-positive breast cancer(having evaluable lesions and an Eastern Cooperative Oncology Group performance status of 0 or 1)using a 3+3 design of escalating BAT8001 doses.Patients received BAT8001 intravenously in a 21-day cycle,with dose escalation in 5 cohorts:1.2,2.4,3.6,4.8,and 6.0 mg/kg.The primary objective was to evaluate the safety and tolerability of BAT8001.Preliminary activity of BAT8001 was also assessed as a secondary objective.Results:Between March 2017 to May 2018,29 HER2-positive breast cancer patients were enrolled.The observed dose-limiting toxicities were grade 4 thrombocytopenia and grade 3 elevated transaminase.The maximum tolerated dose was determined to be 3.6 mg/kg.Grade 3 or greater adverse events(AEs)occurred in 14(48.3%)of 29 patients,including thrombocytopenia in 12(41.4%)patients,aspartate aminotransferase increased in 4(13.8%)patients,γ-glutamyl transferase increased in 2(6.9%)patients,alanine aminotransferase increased in 2(6.9%)patients,diarrhea in 2(6.9%)patients.Objective response was observed in 12(41.4%,95%confidence interval[CI]=23.5%-61.1%)and disease control(including patients achieving objective response and stable disease)was observed in 24(82.8%,95%CI=64.2%-94.2%)patients.Conclusions:BAT8001 demonstrated favorable safety profiles,with promising anti-tumor activity in patients with HER2-positive locally advanced or metastatic breast cancer.BAT8001 has the potential to provide a new therapeutic option in patients with metastatic HER2-positive breast cancer. | Ruoxi Hong Wen Xia Liye Wang Kaping Lee Qianyi Lu Kuikui Jiang Shengfeng Li Jinquan Yu Jin Wei Weijia Tang Danyang Zhou Xin An Jiajia Huang Cong Xue Xiwen Bi Yanxia Shi Zhongyu Yuan Fei Xu Shusen Wang | 2021 | Cancer Communications2021，41，2： | 2 |
| 6 | A hexon and fiber-modified adenovirus expressing CD40L improves the antigen presentation capacity of dendritic cells 显示文摘 | Liljenfeldt L Yu Di Chen Liye | 2014 | J Immunother2014，37，3： | 1 |
| 7 | Intermetallics characterization of lead-free solderjoints under isothermal aging显示文摘 | CHOUBEY A YU H OSTERMAN M PECHT M YUN F LIY H XU M | 2008 | Journal of Electronic Materials2008，37，8： | 1 |
| 8 | Molecular characterization and serodiagnosis analysis of a novel lysophospholipase from Clonorchis sinensis显示文摘 | MaC HuX HuF LiY ChenX ZhouZ Lu F XuJ Wu Z Yu X | 2007 | Parasitol Res2007，02，： | 1 |
| 9 | 3D paper-cutmodeling animation显示文摘 | LIY YU JH SHI J Y | | 0，，4： | 1 |
| 10 | Laparoscopic Radical Correction Combined With Extensive Lymphadenectomy and Pelvic Autonomic Nerve Preservation for Mid-to-Low Rectal Cancer显示文摘 | Tao Liu Chao Zhang PeiWu Yu Jun Chen Dongzhu Zeng Lu Gan Wei Lv LiYe Liu Xiaochu Yan | 2011 | Clinical Colorectal Cancer2011，，3： | 1 |
| 11 | Rolling Bearing Fault Diagnosis Based on CEEMD and Time Series Modeling显示文摘 | Liye Zhao Wei Yu Ruqiang Yan | 2014 | Mathematical Problems in Engineering2014，38，4： | 1 |
| 12 | Enhancement of Photo-Thermal Conversion Performance of the Nanofluids Through Spectral Complementarity between Silver and Cesium Tungstate Oxide Nanoparticles显示文摘Nanofluids with full-spectrum absorption properties are highly desirable for direct solar thermal energy conversion applications.In this work,Ag and CsW03 nanofluids,which exhibit absorption both in the visible and near-infrared(NIR)region,are integrated to obtain two>component hybrid nanofluids.The hybrid nanofluids show broad band absorption with a solar weighted absorption fraction of 99.6%,compared to 18%and 54%for the base liquid(ethylene glycol)and CsW03 nanofluids,respectively.The highest photo-thermal conversion performance for the hybrid nanofluids is obtained with Ag/CsW03 weight ratio of 3/7.The solar thermal conversion efficiency of the optimum hybrid nanofluids is 67%,10%and 15%higher than single Ag and CsW03 nanofluids.The two-component hybrid nanofluid provides an alternative for making the best use of solar energy. | LIU Changqing ZHANG Liy HE Yan Yu Wei | 2020 | Journal of Thermal Science2020，29，5： | 1 |
| 13 | Studies of different kinds of fiber pretreating on the properties of PLA/sweet sorghum fiber composites 显示文摘 | Zhong Jing Zhang Liye Yu Jianliang | 2010 | Journal of Applied Polymer Science2010，117，3： | 1 |
| 14 | Magnetic field analysis of HTS transformer windings with high currents显示文摘 | Min Chen Yunjia J Yu Liye Y Xiao | 2003 | IEEE Trans on Applied Superconductivity2003，13，6： | 1 |
| 15 | Effect of bicyclol on cisplatin-Induced hepatotoxicity in the hepatoearcinoma 22 turnout-bearing mice 显示文摘 | Yu YN ChenH LiY | 2009 | Basic Clin Pharmacol Toxicol2009，104，4： | 1 |
| 16 | SOAP3: ultra-fast GPU- based parallel alignment tool for short reads 显示文摘 | Liu C M Wong T WuE LuoR Yiu S M LiY Wang B Yu C Chu X Zhao K Li R Lam T W | 2012 | Bioinformatics2012，28，6： | 1 |
| 17 | Effects of the composition of standard reference material on the accuracy of determinations of 137Pb and 210Cs in soils with gamma spectrometry 显示文摘 | LiY GengX C Yu H Q Wan G J | 2011 | Applied Radiation and Isotopes2011，69，： | 1 |
| 18 | A New Parameter as an Indicator of the Degree of Deformation of Coals显示文摘The deformation of coal is effected by thermal effect, pressures and tectonic stress, and the tectonic stress is the principal influence factor. However, the proposition of a useful quantitative index that responds to the degree of deformation of coals quantitatively or semi-quantitatively has been a long-debated issue. The vitrinite reflectance ellipsoid, that is, the reflectance indication surface(RIS) ellipsoid is considered to be a strain ellipsoid that reflects the sum of the strain increment caused by stress in the process of coalification. It has been used to describe the degree of deformation of the coal, but the effect of the anisotropy on the RIS ellipsoid has not yet been considered with regards to non-structural factors. In this paper, Wei's parameter(ε) is proposed to express the deformation degree of the strain ellipsoid based on considering the combined influence of thermal effect, pressure and tectonic stress. The equation is as follows: ε=√[(ε_1-ε_0)~2+(ε_2-ε_0)~2+(ε_3-ε_0)~2]/3, where ε_1=lnR_(max), ε_2=lnR_(int), ε_3=lnR_(min), and ε_0=(ε_1+ε_2+ε_3)/3. Wei's parameter represents the distance from the surface to the spindle of the RIS logarithm ellipsoid; thus, the degree of deformation of the strain ellipsoid is indicated quantitatively. The formula itself, meanwhile, represents the absolute value of the degree of relative deformation and is consequently suitable for any type of deformation of the strain ellipsoid. Wei's parameter makes it possible to compare degrees of deformation among different deformation types of the strain ellipsoid. This equation has been tested in four types of coal: highly metamorphic but weakly deformed coal of the southern Qinshui Basin, highly metamorphic and strongly deformed coal from the Tianhushan coal mining area of Fujian, and medium metamorphic and weakly or strongly deformed coal from the Huaibei Coalfield. The results of Wei's parameters are consistent with the actual deformation degrees of the coal reservoirs determined by other methods, which supports the effectiveness of this method. In addition, Wei's parameter is an important complement to the indicators of the degrees of deformation of coals, which possess certain theoretical significance and practical values. | Mingming Wei Yiwen Ju Quanlin Hou Guochang Wang Liye Yu Wenjing Zhang Xiaoshi Li | 2017 | Journal of Earth Science2017，28，2： | 1 |
| 19 | Removal of dissolved oxygen from water using a Pd-resin based catalytic reactor显示文摘The removal of dissolved oxygen(DO)from water was studied experimentally in a Pd-resin base catalyst reactor using purified hydrogen gas as a reducing agent.The effects of various operating conditions,such as hydrogen and waterflow rates,height of the catalytic resin bed,temperature,pH value and run time,on the removal of DO,had been studied extensively.The results shows that DO could be removed by the reactor from ppm to ppb levels at ambient temperature.Increases of temperature,H2 gas rate and the height of the catalytic resin were helpful to improve the DO removal rate.The change of pH value from 4 to 12 resulted in no effect on DO removal.Reaction time was the key factor to control the DO removal efficiency.Only when the reaction time was longer than 2.3 minutes under the experimental conditions,could a very low DO level be achieved. | Wenxin SHI Chongwei CUI Liye ZHAO Shuili YU Xia YUN | 2009 | Frontiers of Chemical Science and Engineering2009，3，1： | 0 |
| 20 | Effects of DOM characteristics from real wastewater on the degradation of pharmaceutically active compounds by the UV/H_(2)O_(2) process显示文摘The characteristics of dissolved organic matter(DOM) can significantly affect the degradation of target compounds by the advanced oxidation processes. In this study, the effects of the different hydrophobicity/hydrophilicity fractions, molecular weight(MW) fractions,fluorescence components and molecular components of DOM extracted from municipal wastewater on the degradation of 4 pharmaceutically active compounds(Ph ACs), including carbamazepine, clofibric acid, atenolol and erythromycin by the UV/H_(2)O_(2) process were investigated. The results showed that the degradation rate constants of 4 Ph ACs decreased dramatically in the presence of DOM. The linear regressions of 4 Ph ACs degradation as a function of specific fluorescence intensity(SFI) are exhibited during the degradation of 4Ph ACs and the SFI may be used to evaluate effect of DOM on target compounds in wastewater. The hydrophobic acid(HPO-A) exhibited the strongest inhibitory effect on degradation of 4 Ph ACs during oxidation process. The small MW fractions of DOM significantly inhibited the degradation of 4 Ph ACs during oxidation process. Among three fluorescence components,hydrophobic humic-like substances may significantly inhibit the degradation of 4 Ph ACs during oxidation process. At the molecular level, the formulas may be derived from terrestrial sources. CHO compound may significantly inhibit the degradation of 4 Ph ACs during oxidation process on formula classes. The unsaturated hydrocarbons, carbohydrates and tannins compounds may significantly inhibit the effectiveness of the UV/H_(2)O_(2) process on compound classes. | Yufei Shi Jinju Geng Xiang Li Yuli Qian Hongzhou Li Liye Wang Gang Wu Qingmiao Yu Ke Xu Hongqiang Ren | 2022 | Journal of Environmental Sciences2022，34，6： | 0 |
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