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336篇 您的检索式:作者名="Lo P H"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Composting salmon farm mortalities with passive areration显示文摘Liao P H Vizcarra A T Chen A Lo K V 1996Compost Science and Utilization1996,2,4:2
3Time domain buffeting analysis of suspension bridge subjected to turbulent wind with effective action angle显示文摘Ding Q Lee P K K Lo S H 2000Journal of Sound and Vibration2000,233,2:1
4Effect on hepatitis B virus DNA levds in children infected with different genotypes显示文摘Sangfelt P Norder H Magnius LO Interferon - alpha 2b treament in hepatitis B carriers 1997Acta Paediatr1997,86,2:1
5Development and applications of the reciprocating plate显示文摘Lo P C Baird M H I Rama Rao N V 1992Column Chem Eng Commun1992,116,:1
6Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-13 supeffamily 显示文摘LO P C H FRASCH M 1999Mechanisms of Development1999,86,12:1
7'Delayed securi- ty price adjustments to financial analysts' forecasts of annual earnings 显示文摘Elgers P T May H Lo Pfeiffer R J 2001The Accounting Review2001,28,:1
8The electrochemical behvior of electroless plated Ni-P alloy in concentrated NaOH solution显示文摘Lo P H Tsai W T Lee J T 1995Journal of the Electrochemical Society1995,142,:1
9Evolution of binary phase TiC/ Ti3SiC2 composites from TiC/Ti/Si by hot - pressed reactive sintering 显示文摘Lo W Nayak P K La H 2010Materials Science and Engineering : B2010,172,1:1
10A decision support framework for strategic purchasing显示文摘 V H Y Lo R T McIvor 2000Journal of Materials Processing Technology2000,,107:1
11显示文摘Wang H Ho H P Lo K C 2008Mater Chem Phys2008,107,:1
12Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters 显示文摘Lo H L Chang T Yam P 2007Gene Ther2007,14,21:1
13Intrauterine contraceptive device migration to the lower urinary tract: report of 2 cases显示文摘Ko P C Lin Y H Lo T S 2011J Minim Invasive Gynecol2011,18,5:1
14Inter-trial analysis of post- movement beta activities in EEG signals using multivariate em- pirical mode decomposition 显示文摘Chang H Lee P Lo M 2013Neural Systems and Rehabili- tation Engineering2013,21,4:1
15Chemically functionalizable nanoporous material n 显示文摘Chui S S Y Lo S M F Charmant J P H 1999Science1999,283,:1
16Vancomycin MIC creep in MRSA isolates from 1997 to 2008 in a healthcare region in Hong Kong显示文摘Ho P L Lo P Y Chow K H et a l 2010J Infect2010,60,11:1
17Cancer-specific gene therapy 显示文摘Lo H W Day C P Hung M C 2005Adv Genet2005,54,14:1
18A rigorous analytical method for doubly periodic cylindrical inclusions under longitudinal shear and its application 显示文摘Jiang C P Xu Y L Cheung Y K Lo S H 2004Mechanics of Materials2004,36,3:1
19Grey and network prediction of suspended solids and chemical oxygen demand in hospital wastewater treatment plant effluent 显示文摘PAI T Y TSAI Y P LO H M 2007Computer and Chemical Engineering2007,31,10:1
20Characterisation of residual principal stresses and their implications on failure of railway rails显示文摘LO K H MUMMERY P BUTTLE D J 2010Engineering Failure Analysis2010,17,6:1
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