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182篇 您的检索式:作者名="Lochhead"
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1低位内镜检查可减少结直肠癌的长期发生率和死亡率显示文摘电子结肠镜检查有助于预防结直肠癌发生,其保护作用的强度和持续时间,特别是对近端结肠的保护作用还需进一步研究。美国麻省总医院胃肠科的Chan博士等人对此进行了研究,他们发现结肠镜检查是有效的结直肠癌筛查方法。研究人员检验了Nurses''健康研究及医疗专业随访研究的受试人群中低位结肠内镜检查(1988至2008,两年一次更新)与结直肠癌发生率(至2010年6月)及结直肠癌死亡率(至2012年6月)之间的相关性。研究由此得出结论:电子结肠镜检查与远端结直肠癌发生率下降相关;电子结肠镜检查与近端结肠癌发生率的适度下降相关。经电子结肠镜检查筛查与结直肠癌死亡率下降相关;而仅电子结肠镜检查与近端结肠癌死亡率的下降相关。与从未接受电子结肠镜检查或电子结肠镜检查超过5年后诊断为结直肠癌的患者相比,电子结肠镜检查后5年内诊断为结直肠癌的患者更易出现CpG岛甲基化现象和微卫星不稳定性。Nishihara R Wu K Lochhead P 2013中华结直肠疾病电子杂志2013,2,4:52
2Mixed reality emergency management:bringing virtual evacuation simulations into real-world built environments显示文摘Computer-based evacuation simulations are important tools for emergency managers.These simulations vary in complexity and include 2D and 3D GIS-based network analyses,agent-based models,and sophisticated models built on documented human behaviour and particle dynamics.Despite the influential role of built environments in determining human movement,a disconnect often exists between the features of the real world and the way they are represented within these simulation environments.The proliferation of emergency management location-aware mobile devices,along with a recent infatuation for augmented reality(AR),has resulted in new wayfinding and hazard assessment tools that bridge this gap,allowing users to visualize geospatial information superimposed on the real world.In this paper,we report research and development that has produced AR geovisual analytical systems,enabling visual analysis of human dynamics in multilevel built environments with complex thoroughfare network infrastructure.We demonstrate prototypes that show how mixed reality visual analysis of intelligent human movement simulations built in virtual spaces can become part of real space.This research introduces a fundamentally new way to view and link simulations of people with the real-world context of the built environment:mixed reality crowd simulation in real space.Ian Lochhead Nick Hedley 2019International Journal of Digital Earth2019,12,2:3
3Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication显示文摘Paul Lochhead Aya Kuchiba Yu Imamura Xiaoyun Liao Mai Yamauchi Reiko Nishihara Zhi Rong Qian Teppei Morikawa Jeanne Shen Jeffrey A. Meyerhardt Charles S. Fuchs Shuji Ogino 2013JNCI Journal of the National Cancer Institute2013,,15:3
4Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication显示文摘Lochhead P Kuchiba A Imamura Y 2013Journal of the National Cancer Institute2013,105,15:1
5Relationships between forest structure, understorey light and regeneration in complex Douglas- fir dominated stands in south-eastern British Columbia显示文摘Lochhead K D Comeau P G 2012Forest Ecology and Management2012,284,:1
6Assessing the role of interfa-cial electrostatics in oriented mineral nucleation at charged mono-layers显示文摘Lochhead M J Letellier S R Vogel V 1997Journal of Physical Chemistry B1997,101,50:1
7Multimodality tissue-mimicking phantom for thermal therapy显示文摘McDonald M Lochhead S Chopra R 2004Phys Med Biol2004,49,4:1
8The Effect of Temperature on Asexual Population Growth of Three Species of Naididae (Oligochaeta) 显示文摘Lochhead G Learner M A 1953Hydrobiologia1953,98,:1
9A chaperone- dependent GSK3 beta transitional intermediate mediates activation-loop autophosphorylation 显示文摘Lochhead PA Kinstrie R Sibbet G 2006Molecular Cell2006,24,4:1
10Intussusception in chil- dren presenting to the emergency department显示文摘Lochhead A Jamjoom R Ratnapalan S 2013Clin Pediatr2013,52,11:1
11Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment显示文摘Aleksandar D. Kostic Eunyoung Chun Lauren Robertson Jonathan N. Glickman Carey Ann Gallini Monia Michaud Thomas E. Clancy Daniel C. Chung Paul Lochhead Georgina L. Hold Emad M. El-Omar Dean Brenner Charles S. Fuchs Matthew Meyerson Wendy S. Garrett 2013Cell Host & Microbe2013,,:1
12Aspirin use, tumor PIK3CAmutation, and colorectal-cancer survival 显示文摘Liao X Lochhead P Nishihara R e t al 2012N Engl J Med2012,367,17:1
13In vivocharacterization of cytokine profiles and viral load duringmurine cytomegalovirus-induced acute myocarditis显示文摘Ritter J T Tang-Feldman Y J Lochhead G R 2010Cardiovasc Pathol2010,19,2:1
14The strong ion gap does not have prognostic value in critically ill patients in a mixed medical/surgical adult ICU 显示文摘Cusack R J Rholdes A Lochhead P 2002Intensive Care Med2002,28,7:1
155-Aminoimidazole-4- carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic gene PEPCK and glucose-6-phosphatase 显示文摘Lochhead P A Salt I P Walker K S 2000Diabetes2000,49,:1
16Identification of A2B5 + CD133-tumor-initiating cells in adult human gliomas显示文摘Ogden AT Waziri AE Lochhead RA 2008Neurosurgery2008,62,2:1
17The strong ion gap does not have prognostic value in critically ill patients in a mixed medical/surgical adult I CU 显示文摘Cusack R Rhodes A Lochhead P 2002Intensive Care Med2002,28,7:1
18Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression显示文摘LOCHHEAD P A COGHLAN M RICE S Q 2001Diabetes2001,50,5:1
19显示文摘Letellier S R Lochhead M Vogel V 1998Biochim Biophy Acta Gen Subject1998,1380,:1
20Gastric cancer显示文摘Lochhead P E1-Omar EM 2008Br Med Bull2008,85,:1
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