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| 1 | Increased brachial-ankle pulse wave velocity is associated with impaired endothelial function in patients with coronary artery disease显示文摘Background Pulse wave velocity and flow-mediated vasodilation (FMD) are widely used as noninvasive modalities for evaluating atherosclerosis. However, it is not known whether pulse wave velocity is related to FMD in patients with coronary artery disease (CAD). Therefore, the present study was designed to investigate the alteration in brachial-ankle pulse wave velocity (baPWV) and endothelial function in CAD patients. Methods Thirty-three patients with CAD and thirty control subjects were recruited for this study. baPWV was measured non-invasively using a VP 1000 automated PWV/ABI analyzer (PWV/ABI, Colin Co. Ltd., Komaki, Japan). Endothelial function as reflected by FMD in the brachial artery was assessed with a high-resolution ultrasound device. Results baPWV was increased in CAD patients compared with control subjects [(1756.1±253.1) cm/s vs (1495.3±202.3) cm/s, P<0.01]. FMD was significantly reduced in CAD patients compared with control subjects [(5.2±2.1) % vs (11.1±4.4) %, P<0.01]. baPWV correlated with FMD (r =-0.68, P<0.001). The endothelium-independent vasodilation induced by sublingual nitroglycerin in the brachial artery was similar in the CAD group compared with the control group. Conclusions CAD is associated with increased baPWV and endothelial dysfunction. Increased baPWV parallels diminished endothelial function. Our data therefore suggest that baPWV can be used as a noninvasive surrogate index in clinical evaluation of endothelial function. | LIU Dong-hong WANG Yan LIAO Xin-xue XU Ming-guo WANG Jie-mei YANG Zhen CHEN Long LU Ming-de LU Kun TAO Jun | 2006 | Chinese Medical Journal2006，，22： | 17 |
| 2 | Transjugular Intrahepatic Portosystemic Shunt Versus Surgical Shunting in the Management of Portal Hypertension显示文摘Background: The purpose of this article was to clarify the optimal management concerning transjugular intrahepatic portosystemic shunts (TIPSs) and surgical shunting in treating portal hypertension. Methods: All databases, including CBM, CNKI, WFPD, Medline, EMBASE, PubMed and Cochrane up to February 2014, were searched for randomized controlled trials (RCTs) comparing TIPS with surgical shunting. Four RCTs, which were extracted by two independent investigators and were evaluated in postoperative complications, mortality, 2- and 5-year survival, hospital stay, operating time and hospitalization charges. Results: The morbidity in variceal rehemorrhage was significantly higher in TIPS than in surgical shunts (odds ratio [OR] = 7.45, 95% confidence interval[C/]: (3.93-14.15), P 〈 0.00001), the same outcomes were seen in shunt stenosis (OR = 20.01,95% CI: (6.67-59.99), P 〈 0.000001 ) and in hepatic encephalopathy (OR = 2.50, 95% CI: (1.63-3.84), P 〈 0.0001 ). Significantly better 2-year survival (OR = 0.66; 95% CI: (0.44-0.98), P ~ 0.04) and 5-year survival (OR = 0.44; 95% CI: (0.30-0.66), P 〈 0.00001) were seen in patients undergoing surgical shunting compared with TIPS. Conclusions: Compared with TIPS, postoperative complications and survival after surgical shunting were superior for patients with portal hypertension. Application of surgical shunting was recommended for patients rather than TIPS. | Long Huang Qing-Sheng Yu Qi Zhang Ju-Da Liu Zhen Wang | 2015 | Chinese Medical Journal2015，，6： | 17 |
| 3 | Implementation and security analysis of practical quantum secure direct communication显示文摘Rapid development of supercomputers and the prospect of quantum computers are posing increasingly serious threats to the security of communication.Using the principles of quantum mechanics,quantum communication offers provable security of communication and is a promising solution to counter such threats.Quantum secure direct communication(QSDC)is one important branch of quantum communication.In contrast to other branches of quantum communication,it transmits secret information directly.Recently,remarkable progress has been made in proof-of-principle experimental demonstrations of QSDC.However,it remains a technical feat to bring QSDC into a practical application.Here,we report the implementation of a practical quantum secure communication system.The security is analyzed in the Wyner wiretap channel theory.The system uses a coding scheme of concatenation of lowdensity parity-check(LDPC)codes and works in a regime with a realistic environment of high noise and high loss.The present system operates with a repetition rate of 1 MHz at a distance of 1.5 kilometers.The secure communication rate is 50 bps,sufficient to effectively send text messages and reasonably sized files of images and sounds. | Ruoyang Qi Zhen Sun Zaisheng Lin Penghao Niu Wentao Hao Liyuan Song Qin Huang Jiancun Gao Liuguo Yin Gui-Lu Long | 2019 | Light(Science & Applications)2019，8，1： | 15 |
| 4 | A study on arsenic trioxide inducing in vitro apoptosis of gastric cancer cell lines显示文摘INTRODUCTION Cell apoptosis,which involves the biologic regulation of the numbers and vital activity of cells,is an important metaboloc process in both normal cells and tumor cells. | Qin Long Gu Ning Li Li Zheng Gang Zhu Hao Ran Yin Yan Zhen Lin | 2000 | World Journal of Gastroenterology2000，6，3： | 12 |
| 5 | Bionic Coupling of Hardness Gradient to Surface Texture for Improved Anti-wear Properties显示文摘 | Long Zheng Jianjun Wu Si Zhang Shishuai Sun Zhihui Zhang Song Liang Zhenning Liu Luquan Ren | 2016 | Journal of Bionic Engineering2016，13，3： | 9 |
| 6 | The Tuerkubantao ophiolite melange in Xinjiang,NW China:New evidence for the Erqis suture zone显示文摘The extension of the suture zone between the Siberian and Kazakhstan continents in China has been a matter of debate because few outcrops of ophiolitic melange have been found so far.The recently found Tuerkubantao ophiolitic melange,which is located east of the Kekesentao Mt.in the Buerjin County of the Chinese Altay,provides an important clue for this problem.This paper presents the results of field investigation,petrology,U-Pb isotope dating of zircons and bulk-rock geochemistry of the Tuerkubantao melange rocks.The melange consists of fault-contacted ultramafic rocks,gabbro, diabase,basalt,flysch and granitoids.The ultramafic-mafic rocks are Mg-rich(Mg~#=4.25—6.35) and w(SiO_2) spans 38.8%—46.8%.Basalt and gabbro are geochemically similar and are characterized by low w(FeO^t)(10.9%),total alkali w(Na_2O+K_2O)=2.58%) and w(TiO_2)(1.17%) and affinity to the Mg-rich tholeiite series.The flat REE and trace-element patterns of the ultramafic-mafic rocks are indicative of their ophiolite origin,i.e.,formation in a mid-oceanic ridge setting.The fragments of low-K gneissic granite formed in suprasubduction or syn-collisional setting.Zircons from gabbro and gneissic granite yielded U-Pb ages of 363 and 355 Ma.respectively,suggesting Late Devonian mid-oceanic spreading and oceanic subduction accompanied by suprasubduction magmatism.The Tiierkubantao ophiolite together with the Qiaoxiahala and Buergen ophiolites of the Kekesentao belt define an ophiolitic melange belt extending along the Erqis fault.This belt probably belongs to the Ural-Zaisan -South Mongolian suture-shear zone formed during the subduction of the Paleo-Asian Ocean and subsequent collision of the Siberian and Kazakhstan continents. | Yuwang Wang Jingbin Wang Lijuan Wang Lingli Long Pingzhi Tang Zhen Liao Huiqiong Zhang Yu Shi | 2012 | Geoscience Frontiers2012，3，5： | 9 |
| 7 | Protective Effects of Quercetin on Cadmium-induced Cytotoxicity in Primary Cultures of Rat Proximal Tubular Cells显示文摘Objective To investigate the protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular(rPT)cells.Methods Primary cultures of rPT cells undergoing exponential growth were incubated with 1.0 μg/mL quercetin and/or cadmium(2.5,5.0 μmol/L),in a serum-free medium at 37 ℃ at different time intervals.Commercial kits were used and flow cytometric analyses were performed on rPT cell cultures to assay apoptosis and oxidative stress.Results Exposure of rPT cells to cadmium acetate(2.5,5.0 μmol/L)induced a decrease in cell viability,caused an increase in apoptotic rate and apoptotic morphological changes.Simultaneously,elevation of intracellular reactive oxygen species,malondialdehyde and calcium levels,depletion of mitochondrial membrane potential and intracellular glutathione,and inhibition of Na +,K +-ATPase,Ca 2+-ATPase,glutathione peroxidase(GSH-Px),catalase(CAT),and superoxide dismutase(SOD)activities were revealed during the cadmium exposure of rPT cells.However,simultaneous supplementation with 1 μg/mL quercetin protected rPT cells against cadmium-induced cytotoxicity through inhibiting apoptosis,attenuating lipid peroxidation,renewing mitochondrial function and elevating the intracellular antioxidants(non-enzymatic and enzymic)levels.Conclusion The present study has suggested that quercetin,as a widely distributed dietary antioxidant,contributes potentially to prevent cadmium-induced cytotoxicity in rPT cells. | WANG Lin LIN Shu Qian HE Yuan Long LIU Gang WANG Zhen Yong | 2013 | Biomedical and Environmental Sciences2013，26，4： | 8 |
| 8 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 9 | Optimization of cantilevered piezoelectric energy harvester with a fixed resonance frequency显示文摘Piezoelectric energy harvesting is widely used to scavenge vibration energy in the environment.For some vibration sources with fixed frequency,cantilevered harvester can generate the energy effectively,so the optimization theory for cantilevered harvester in such an application is needed.In this article,we present the theoretical and experimental studies of the cantilevered piezoelectric energy harvester with a fixed resonance frequency.An analytical model based on energy method is used to estimate the open-circuit voltage and generated energy.Considering that the harvester may be subjected to the static force or steady-state sinusoidal vibration excitation,static and dynamic analysis is performed for device structure to achieve efficient energy.In the analysis,the effects of geometrical dimension on the energy harvesting performance are discussed comprehensively.Eventually,a prototype is designed and fabricated using(1-x)Pb(Mg1/3Nb2/3)O3-xPbTiO3(PMN-PT)single crystal with ultrahigh piezoelectric properties and coupling factor.Performances of the cantilever with different clamped length are evaluated under sinusoidal vibration excitation,proving the good consistency between experimental results and theoretical prediction.The established analysis can provide useful guidelines for the structure design of cantilevered piezoelectric energy harvester with a fixed resonance frequency. | LIANG Zhu XU ChunDong REN Bo DI WenNing LI Long LUO HaoSu CHEN Zhen SU Jun | 2014 | Science China(Technological Sciences)2014，57，6： | 6 |
| 10 | Heat shock protein 72 normothermic ischemia,and the impact of congested portal blood reperfusion on rat liver显示文摘INTRODUCTIONFrom the technical aspect of liver surgery ,control of bleeding during hepatic parenchymal resection is one of the most important procedures in hepatectomy .Pringle,s maneuver ,a temporary cross-clamping of the hepatoduodnal ligament ,has often been used for this purpose[1],This is the simplest and userul technique to reduce intraoperative blood loss . | Chao Liu Dai~1 Zhen Long Xia~1 Makoto Kume~2 Yuzo Yamamoto~2 Kazuhiko Yamagami~2 Nobuhiro Ozaki~2 Yoshio Yamaoka~2 ~1Department of Surgery,The Second Clinical College of China Medical University,Shenyang 110003,Liaoning Province,China ~2Department of Gastroenterological Surgery,Kyoto University Graduate School of Medicine,Kyoto,Japan | 2001 | World Journal of Gastroenterology2001，7，3： | 6 |
| 11 | International experience of green development in Western China:an overall review of policy and practice显示文摘Green development emphasizes co-development between economic and environmental dimensions,and is a peoplecentered sustainable development approach.Western China demands green development,and international experience could provide necessary,unique and important help and support for Western China to achieve its green development goals.This paper has made a comprehensive overall review and analysis of international experience in green development policy and its implementation,in particular,OECD countries'(mostly Australia and Canada) experience have been analyzed following the major policy foci defined by the Task Force on Strategy and Policies on Environment and Development in Western China initiated by China Council for International Cooperation on Environment and Development(CCICED).Data and information were gathered from the field surveys and investigations,expert meetings,as well as literature review.The main sessions include policy framework and road map establishment,implementation and performance assessment,co-development between economic development and environmental protection,as well as green employment and poverty alleviation.The paper has addressed five policy considerations for the future promotion of green development in Western China. | Lin Zhen Jie Hu Bingzhen Du Jiyuan Liu Chuanzhun Sun Ruizi Wu Xin Long Qiang Zhang | 2015 | Chinese Journal of Population,Resources and Environment2015，13，4： | 5 |
| 12 | Experimental free-space quantum secure direct communication and its security analysis显示文摘We report an experimental implementation of free-space quantum secure direct communication based on single photons.The quantum communication scheme uses phase encoding,and the asymmetric Mach–Zehnder interferometer is optimized so as to automatically compensate phase drift of the photons during their transitions over the free-space medium.At a 16 MHz pulse repetition frequency,an information transmission rate of 500 bps over a 10 m free space with a mean quantum bit error rate of 0.49%±0.27%is achieved.The security is analyzed under the scenario that Eve performs the collective attack for single-photon state and the photon number splitting attack for multi-photon state in the depolarizing channel.Our results show that quantum secure direct communication is feasible in free space. | DONG PAN ZAISHENG LIN JIAWEI WU HAORAN ZHANG ZHEN SUN DONG RUAN LIUGUO YIN AND GUI LU LONG | 2020 | Photonics Research2020，8，9： | 5 |
| 13 | Interval mapping for red/green skin color in Asian pears using a modified QTL-seq method显示文摘Pears with red skin are attractive to consumers and provide additional health benefits.Identification of the gene(s)responsible for skin coloration can benefit cultivar selection and breeding.The use of QTL-seq,a bulked segregant analysis method,can be problematic when heterozygous parents are involved.The present study modified the QTL-seq method by introducing a|Δ(SNP-index)|parameter to improve the accuracy of mapping the red skin trait in a group of highly heterozygous Asian pears.The analyses were based on mixed DNA pools composed of 28 red-skinned and 27 green-skinned pear lines derived from a cross between the‘Mantianhong’and‘Hongxiangsu’red-skinned cultivars.The‘Dangshansuli’cultivar genome was used as reference for sequence alignment.An average single-nucleotide polymorphism(SNP)index was calculated using a sliding window approach(200-kb windows,20-kb increments).Nine scaffolds within the candidate QTL interval were in the fifth linkage group from 111.9 to 177.1 cM.There was a significant linkage between the insertions/deletions and simple sequence repeat markers designed from the candidate intervals and the red/green skin(R/G)locus,which was in a 582.5-kb candidate interval that contained 81 predicted protein-coding gene models and was composed of two subintervals at the bottom of the fifth chromosome.The ZFRI 130-16,In2130-12 and In2130-16 markers located near the R/G locus could potentially be used to identify the red skin trait in Asian pear populations.This study provides new insights into the genetics controlling the red skin phenotype in this fruit. | Huabai Xue Ting Shi Fangfang Wang Huangkai Zhou Jian Yang Long Wang Suke Wang Yanli Su Zhen Zhang Yushan Qiao Xiugen Li | 2017 | Horticulture Research2017，4，1： | 5 |
| 14 | Generic security analysis framework for quantum secure direct communication显示文摘Quantum secure direct communication provides a direct means of conveying secret information via quantum states among legitimate users.The past two decades have witnessed its great strides both theoretically and experimentally.However,the security analysis of it still stays in its infant.Some practical problems in this field to be solved urgently,such as detector efficiency mismatch,side-channel effect and source imperfection,are propelling the birth of a more impeccable solution.In this paper,we establish a new framework of the security analysis driven by numerics where all the practical problems may be taken into account naturally.We apply this framework to several variations of the DL04 protocol considering real-world experimental conditions.Also,we propose two optimizing methods to process the numerical part of the framework so as to meet different requirements in practice.With these properties considered,we predict the robust framework would open up a broad avenue of the development in the field. | Zhang-Dong Ye Dong Pan Zhen Sun Chun-Guang Du Liu-Guo Yin Gui-Lu Long | 2021 | Frontiers of physics2021，16，2： | 5 |
| 15 | In situ observation of C_(60)(C(COOH)_(2))_(2) interacting with living cells using fluorescence microscopy显示文摘The interactions between nanoparticles and living cells were investigated by an imaging technique of fluorescence microscopy. For this pur- pose, the C60 derivative C60(C(COOH)2)2, a thera- peutic agent for degeneration diseases of central nervous system, was synthesized, purified and characterized. Its interaction with the living cell and penetration of the cellular membrane were in situ studied using the real time imaging technique, and its potential cytotoxicity was also examined by flow cy- tometry. The results indicate that C60(C(COOH)2)2 can easily enter cells, and is mainly located in cytoplasm by fluorescein labeling. Furthermore, C60(C(COOH)2)2 can carry the molecule that cannot cross cellular membranes into cells, because fluo- rescein compound itself cannot enter the cell or ad- here to membrane. At concentrations ranging from 1×10?2 to 1×102 mg/L, C60(C(COOH)2)2 does not show any detectable cytotoxicity. | YE Chang CHEN Chunying CHEN Zhen MENG Huan XING Li JIANG Yaxin YUAN Hui XING Gengmei ZHAO Feng ZHAO Yuliang CHAI Zhifang FANG Xiaohong HAN Dong CHEN Long WANG Chen WEI Taotao | 2006 | Chinese Science Bulletin2006，51，9： | 4 |
| 16 | Back-n white neutron source at CSNS and its applications显示文摘Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn. | Jing-Yu Tang Qi An Jiang-Bo Bai Jie Bao Yu Bao Ping Cao Hao-Lei Chen Qi-Ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 无 | 2021 | Nuclear Science and Techniques2021，32，1： | 4 |
| 17 | Alteration of tumor suppressor gene p16 and Rb in gastric cancinogesis显示文摘Alterationoftumorsuppressorgenep16andRbingastriccancinogesisZHOUQi1,ZOUJianXiang2,CHENYuLong2,YUHuiZhen3,WANGLiDong1,LIYo... | ZHOU Qi1, ZOU JianXiang2, CHEN YuLong2, YU HuiZhen3,WANG LiDong1, LI YongXin1, GUO HuaQin1, GAO ShanShan1, and QIU SongLian11Laboratory for Cancer Research, Medical Experimental Center, 2Department of Gas | 1997 | World Journal of Gastroenterology1997，3，4： | 4 |
| 18 | Coupling Effect of Morphology and Mechanical Properties Contributes to the Tribological Behaviors of Snake Scales显示文摘 | Long Zheng Yinghui Zhong Yihang Gao Jiayi Li Zhihui Zhang Zhenning Liu Luquan Ren | 2018 | Journal of Bionic Engineering2018，15，3： | 4 |
| 19 | eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses显示文摘It has become increasingly challenging for researchers to analyze the exponentially expanding amount of multi-omic data.Here,we describe multi-functional software named evolutionary GenotypePhenotype Systems(eGPS)that enables users to perform comprehensive multiomic and evolutionary analyses.The eGPS combines the power of cloud computing and the advantage of desktop application,has a user-friendly graphic interface and is highly interactive. | Dalang Yu Lili Dong Fangqi Yan Hailong Mu Bixia Tang Xiao Yang Tao Zeng Qing Zhou Feng Gao Zhonghuang Wang Ziqian Hao Hongen Kang Yi Zheng Hongwei Huang Yuzhang Wei Wei Pan Yaochen Xu Junwei Zhu Shilei Zhao Ciran Wang Pengyu Wang Long Dai Mushan Li Li Lan Yiwei Wang Hua Chen Yi-Xue Li Yun-Xin Fu Zhen Shao Yiming Bao Fangqing Zhao Luo-Nan Chen Guo-Qing Zhang Wenming Zhao Haipeng Li | 2019 | National Science Review2019，6，5： | 4 |
| 20 | Damage to Hippocampus of Rats after Being Exposed to Infrasound显示文摘Objective The objective was to observe damage of hippocampus in rats after exposure to infrasound, and to assess HSP70 expression in hippocampus. Methods SD rats in the experimental group were exposed to 140 d B(8 Hz) infrasound for 2 h per day for 3 days. The morphology of the hippocampus was examined by transmission electronic microscopic(TEM). Cell apoptosis was observed by TUNEL staining at 0 h, 24 h, 48 h, and 2 w after exposure. HSP70 expression was detected by immunohistochemistry(IHC) and Western blotting(WB). Results TEM showed that hippocampus was significantly damaged by exposure, and exhibited recovery 1 week after exposure. The TUNEL data showed that neuronal apoptosis after exposure was significantly higher than in the control rats at 24 h and 48 h, and the apoptotic cells decreased one week after exposure. IHC and WB showed HSP70 expression was significantly higher in the exposed rats, peaked at 24 h. Conclusion Exposure to 140 d B(8 Hz) infrasound for 2 h per day for 3 days appeared to induce damage to the hippocampus of rats, based on changes in ultrastructure and increased cell apoptosis. However, recovery from the damage occurred overtime. HSP70 expression also increased after the exposure and decreased by 48 h. | ZHANG Meng Yao CHEN Chen XIE Xue Jun XU Sheng Long GUO Guo Zhen WANG Jin | 2016 | Biomedical and Environmental Sciences2016，29，6： | 4 |
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