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| 1 | Longitudinal study of a community hospital integrated model for diabetes management in the Beijing Jingsong community显示文摘Objective:To determine the effects of a community hospital integrated model on the longitu-dinal management of diabetic patients.Methods:Four hundred forty-one patients with type 2 diabetes residing in Jingsong Commu-nity were randomly assigned to intensive and standard groups.Metabolic parameters were meas-ured in the two groups at baseline and after 36 months of management to compare the rate of goal achievement.Results:After comprehensive management,the overall control rate in the intensive group was increased from 2.7%to 9.6%compared with 2.3%-4.5%in the standard group.Specifically,the control rates for fasting plasma glucose,glycosylated hemoglobin,and blood pressure in the intensive group were significantly increased from 54.1%,40.0%,and 68.2%to 85.5%,74.6%,and 89.1%,respectively.The control rate for glycosylated hemoglobin in the intensive group was significantly higher than the standard group after 36 months of treatment.Conclusion:The community hospital integrated model for longitudinal management effec-tively improved the control rate of glycosylated hemoglobin and the overall control rate in patients with type 2 diabetes. | Jiandong Zhang Ning Zhuang Mingxia Yuan Lijuan Gao Chuan Bian Huaining Chen Qing Chi Suqing Hui Guiying Li Yanli Su Hongsong Bao Gang Wan Guangran Yang Shenyuan Yuan | 2014 | Family Medicine and Community Health2014，2，1： | 7 |
| 2 | Interval mapping for red/green skin color in Asian pears using a modified QTL-seq method显示文摘Pears with red skin are attractive to consumers and provide additional health benefits.Identification of the gene(s)responsible for skin coloration can benefit cultivar selection and breeding.The use of QTL-seq,a bulked segregant analysis method,can be problematic when heterozygous parents are involved.The present study modified the QTL-seq method by introducing a|Δ(SNP-index)|parameter to improve the accuracy of mapping the red skin trait in a group of highly heterozygous Asian pears.The analyses were based on mixed DNA pools composed of 28 red-skinned and 27 green-skinned pear lines derived from a cross between the‘Mantianhong’and‘Hongxiangsu’red-skinned cultivars.The‘Dangshansuli’cultivar genome was used as reference for sequence alignment.An average single-nucleotide polymorphism(SNP)index was calculated using a sliding window approach(200-kb windows,20-kb increments).Nine scaffolds within the candidate QTL interval were in the fifth linkage group from 111.9 to 177.1 cM.There was a significant linkage between the insertions/deletions and simple sequence repeat markers designed from the candidate intervals and the red/green skin(R/G)locus,which was in a 582.5-kb candidate interval that contained 81 predicted protein-coding gene models and was composed of two subintervals at the bottom of the fifth chromosome.The ZFRI 130-16,In2130-12 and In2130-16 markers located near the R/G locus could potentially be used to identify the red skin trait in Asian pear populations.This study provides new insights into the genetics controlling the red skin phenotype in this fruit. | Huabai Xue Ting Shi Fangfang Wang Huangkai Zhou Jian Yang Long Wang Suke Wang Yanli Su Zhen Zhang Yushan Qiao Xiugen Li | 2017 | Horticulture Research2017，4，1： | 5 |
| 3 | The characteristics and origins of cleat in coal from Western North China 显示文摘 | Xianbo Su Yanli Feng Jiangfeng Chen | 2001 | International Journal of Coal Geolo- gy2001，47，1： | 1 |
| 4 | Effect of nitric oxide on pericarp browning of harvested longan fruit in relation to phenolic metabolism显示文摘 | Xuewu Duan Xinguo Su Yanli You | 2007 | Food Chemistry2007，104，： | 1 |
| 5 | Breaking and characteristics of Ganoderma lucidum spores by high speed entrifugal shearing pulverizer显示文摘 | Jingjing Ma Zhengyi Fu Peiyan Ma Yanli Su Qingjie Zhang | 2007 | Journal of Wuhan University of Technology - Mater Sci Ed2007，，4： | 1 |
| 6 | The nano pulverization of traditional Chinese medicine Liuwei Dihuang显示文摘 | MA Peiyan FU Zhengyi SU Yanli MA Jingjing | 2006 | Journal of Wuhan University of Technology - Mater Sci Ed2006，，2： | 1 |
| 7 | Simple Vanilla Derivatives for Long-Lived Room-Temperature Polymer Phosphorescence as Invisible Security Inks显示文摘Developing novel long-lived room-temperature polymer phosphorescence(RTPP)materials could significantly expand their application scope.Herein,a series of RTPP materials based on eight simple vanilla derivatives for security ink application are reported.Attributed to strong mutual hydrogen bonding with polyvinyl alcohol(PVA)matrix,vanilla-doped PVA films exhibit ultralong phosphorescence emission under ambient conditions observed by naked eyes,where methyl vanillate shows the longest emission time up to 7 s.Impressively,when vanilla-doped PVA materials are utilized as invisible security inks,and the inks not only present excellent luminescent emission stability under ambient conditions but also maintain perfect reversibility between room temperature and 65℃ for multiple cycles.Owing to the unique RTPP performance,an advanced anticounterfeiting data encoding/reading strategy based on handwriting technology and complex pattern steganography is developed. | Yongfeng Zhang Zhonghao Wang Yan Su Yan Zheng Wenji Tang Chaolong Yang Hailong Tang Lunjun Qu Youbing Li Yanli Zhao | 2021 | Research2021，，1： | 1 |
| 8 | Wearable battery-free theranostic dental patch for wireless intraoral sensing and drug delivery显示文摘Dental caries caused by oral microbiome dysbiosis with the elevation of acidogenic bacteria is the most prevalent noncommunicable disease worldwide.Early prevention and timely fluoride treatment are crucial for caries lesion management.Herein,to address the challenges of in situ sensing and topical drug delivery within the oral cavity,a miniaturized,battery-free,and wearable dental patch system was developed for microenvironment monitoring and controlled fluoride treatment.With the integration of near-field communication,the dental patch realizes wireless energy harvesting and data transmission with mobile terminals like smartphones when attached conformally to the tooth surface.The acidic microenvironment caused by bacterial metabolism are electrochemically detected,while fluorides can be delivered locally from the electric-responsive drug delivery electrode for on-demand treatment.As flexible electronics armed to the teeth,this intraoral theranostic wearable system provides an inspiring platform for point-of-care monitoring and treatment of dental caries and oral diseases. | Zhenghan Shi Yanli Lu Shuying Shen Yi Xu Chang Shu Yue Wu Jingjiang Lv Xin Li Zupeng Yan Zijian An Chaobo Dai Lingkai Su Fenni Zhang Qingjun Liu | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 9 | The potential of ionic liquids in biopharmaceutical engineering显示文摘Biopharmaceuticals,such as proteins,peptides,nucleic acids and vaccines,bring about great hopes for the prevention and treatment of various diseases,but the industrialization of these products still faces challenges such as structural instability,inefficient bioactivity and low bioavailability.Ionic liquids(ILs),the marvelous solvent media with inimitable and tunable properties,may provide alternative solutions to overcome the above problems of biopharmaceutical industry.Progress has gradually been made through studies by combination of ILs with biomacromolecules.The applications involved the stabilization,protection,and delivery of biopharmaceuticals.Recent trends are being forwarded to using ILs in vaccines and nucleic acid drugs.However,challenges remain on the toxicity and safety issues.Besides,the cost of adding ILs to the benefits of biopharmaceuticals need to be considered. | Xuan Lin Zhiguo Su Yanli Yang Songping Zhang | 2021 | Chinese Journal of Chemical Engineering2021，34，2： | 1 |
| 10 | Characteristics and origins in coal from Western North China显示文摘 | Xianbo Su Yanli Feng Jiangfeng Chen | 2001 | International Journal of Coal Geology2001，，47： | 1 |
| 11 | Effeect of nitric oxide on pericarp browning of harvested longan fruit in relation to pheNOlic metabolism显示文摘 | Xuewu Duan Xingguo Su Yanli You | 2007 | Food chemistry2007，104，2： | 1 |
| 12 | Effect of nitric oxide on pericarp browning of harvested longan fruit in relation to phenolic metabolism显示文摘 | Duan Xuewu Su Xinguo You Yanli | 2007 | Food Chemistry2007，104，： | 1 |
| 13 | Catalytic performance of chloromethane transformation for light olefins production over SAPO-34 with different Si content显示文摘 | Yingxu Wei Dazhi Zhang Yanli He Lei Xu Yue Yang Bao-Lian Su Zhongmin Liu | 2007 | Catalysis Letters (-)2007，，1： | 1 |
| 14 | Denitrification of coking wastewater with micro-electrolysis显示文摘 | Yanli Lv Yanqiu Wang Mingjun Shan Xue Shen Ying Su | 2011 | Journal of Environmental Sciences2011，，： | 1 |
| 15 | Angiographic uterine artery chemoembolization followed by vacuum aspiration: an efficient and safe treatment for managing complicated cesarean scar pregnancy显示文摘 | Xianming Yin Shili Su Baihua Dong Yanli Ban Chunhai Li Bingcui Sun | 2012 | Archives of Gynecology and Obstetrics2012，，5： | 1 |
| 16 | Effect of nitric oxide on pericarp browning of harvested longan fruit in relation to phenolic metabolism显示文摘 | Xue Wu Duan Xinguo Su Yanli You | 2007 | Food Chemistry2007，104，： | 1 |
| 17 | Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma显示文摘Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adult gliomas. Mapping gliomas into developmental programs may uncover new vulnerabilities that are not strictly related to genomic alterations. After identifying conserved gene modules co-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adult gliomas in a histological subtype- and grade-independent manner. By using cohorts of bulk samples, paired primary and recurrent samples, multi-region samples from the same glioma, single-cell RNA-seq samples, and clinical samples, we here demonstrate the temporal and spatial stability of the EM and PM subtypes. The EM and PM subtypes, which progress in a subtype-specific mode, are robustly maintained in paired longitudinal samples. Elevated activities of cell proliferation, genomic instability and microenvironment, rather than subtype switching, mark recurrent gliomas. Within individual gliomas, the EM/PM subtype was preserved across regions and single cells. Malignant cells in the EM and PM gliomas were correlated to neural stem cell and oligodendrocyte progenitor cell compartment, respectively. Thus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas evolve within a neurodevelopmental framework of the EM and PM molecular subtypes. The dysregulated developmental pathways embedded in these molecular subtypes may contain subtype-specific vulnerabilities. | Jing Feng Zheng Zhao Yanfei Wei Zhaoshi Bao Wei Zhang Fan Wu Guanzhang Li Zhiyan Sun Yanli Tan Jiuyi Li Yunqiu Zhang Zejun Duan Xueling Qi Kai Yu Zhengmin Cong Junjie Yang Yaxin Wang Yingyu Sun Fuchou Tang Xiaodong Su Chuan Fang Tao Jiang Xiaolong Fan | 2023 | Frontiers of Medicine2023，17，2： | 0 |
| 18 | Periodontitis as a promoting factor of T2D: current evidence and mechanisms显示文摘Periodontitis is an infectious disease caused by an imbalance between the local microbiota and host immune response.Epidemiologically,periodontitis is closely related to the occurrence,development,and poor prognosis of T2D and is recognized as a potential risk factor for T2D.In recent years,increasing attention has been given to the role of the virulence factors produced by disorders of the subgingival microbiota in the pathological mechanism of T2D。 | Yuan Su Leilei Ye Chen Hu Yanli Zhang Jia Liu Longquan Shao | 2023 | International Journal of Oral Science2023，15，2： | 0 |
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