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| 1 | Proteome identification of binding-partners interacting with cell polarity protein Par3 in Jurkat cells显示文摘evolutionarily 保存的房间极性蛋白质 Par3,像支架的 PDZreontaining 蛋白质,在上皮的房间极性的建立和维护起一个关键作用。尽管在在上皮的房间建立房间极性的 Par3 的角色强烈地被探索了,在造血的房间的 Par3 的功能留下逃犯。处理这个问题,我们产生了 Par3 PDZ 领域的 GST 熔化蛋白质。由把 GST-pull-down 途径与液体层析双人脚踏车团 spectrometry 相结合,我们在 Jurkat 房间(一根 T 房间线) 识别了 Par3 的 PDZ 领域的 10 潜在的新奇有约束力的蛋白质。有三蛋白质的 Par3 的相互作用—原子运输蛋白质 importin-α4 和 proteasome 使活跃之物 PA28β 和 PA28γ—被证实在 vitro 绑定试金, co-immunoprecipitation 试金和免疫荧光显微镜学使用。我们的结果有潜力揭开在血房间的房间极性蛋白质 Par3 的新奇功能。 | Ying Zhou Longhou Fang Dan Du Wenchao Zhou Xiujing Feng Jiwu Chen Zhe Zhang Zhengjun Chen | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 2 |
| 2 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair显示文摘分区有缺陷者 3 (Par3 ) ,在 conservedPar3/Par6/aPKC 建筑群的一个关键部件,在房间极性的戏基础角色。此处,我们报导 Ku70 和通过试管内绑定试金的蛋白质由液体层析双人脚踏车质谱法跟随了的 Ku80 同样新奇的交往 Par3 的鉴定。Ku70/Ku80 蛋白质是 DNA 依赖的蛋白激酶(DNA-PK ) 的二个关键规章的子单元,它在修理双海滨脱氧核糖核酸裂缝(DSB ) 起一个必要作用。我们决定 Par3 withKu70/Ku80 的原子协会被 y 照耀(红外) 提高,有势力 DSB inducer。而且, DNA-PKcs, DNA-PK 的催化子单元,响应红外与 Par3/Ku70/Ku80 建筑群交往了。Par3over 表示或击倒分别地能够 up- 或 downregulat-ing DNA-PK 活动。而且, Par3 击倒的房间被发现在随机的原生质标志集成有缺点,在 DSB 修理追随者红外有缺点、对射线敏感,类似于 Ku70knockdown 房间的显型。这些调查结果作为 DNA-PK 建筑群的一个新奇部件识别 Par3 并且含有到 DSB 修理的房间极性的一个意外连接。 | Longhou Fang YiGuo Wang Dan Du Guang Yang Tim Tak Kwok Siu Kai Kong Benjamin Chen David J Chen Zhengjun Chen | 2007 | Cell Research2007，17，2： | 2 |
| 3 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair显示文摘The author affiliations were mixed up in the previous published version. The third fund number of National NaturalScience Foundation of China in the Acknowledgments was wrong, it should be '30270335'. The Shanghai MunicipalCouncil for Science and Technology (No.06DZ22032) was missed in the Acknowledgments. There are some labelingand production errors in Figure 2A, Figure 3B and 3C, Figure 5C, Figure 6B and 6E, Figure 7B and 7D. In Figure 2A,left panel 'A431' should be 'Par3'. In Figure 3B and 3C, 'anti-Par3CT' should be 'anti-Par3LCT', 'GST-Par3CT'should be 'GST-Par3LCT'. In Figure 5C, the second arrow indicating 'Lamin B' should be '[3-tubulin'. In Figure 6Bright panel, the molecular weight for ?-actin should be '43' instead of'200'. In Figure 6E, 'Par3' should be 'Par3i'. Themolecular weight for the DNA-PKcs panel should be the same as the p-DNA-PKcs. In Figure 7B, the time point '240'in the left panel should be '120'; in the right panel of Figure 7B, the title for the y axis should be 'DNA released (%)'.In Figure 7D, the title for the y axis should be 'Survival (%)', and the scale for the y axis should be '100, 10 and 1'. These corrections do not affect the conclusions of the study. We apologize for any inconvenience this may havecaused. | Longhou Fangt YiGuo Wang Dan Dut Guang Yang Tim Tak Kwok Siu Kai Kong Benjamin Chen David J Chen Zhengjun Chen | 2007 | Cell Research2007，17，6： | 1 |
| 4 | Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity显示文摘 | Yury I. Miller Soo-Ho Choi Philipp Wiesner Longhou Fang Richard Harkewicz Karsten Hartvigsen Agnès Boullier Ayelet Gonen Cody J. Diehl Xuchu Que Erica Montano Peter X. Shaw Sotirios Tsimikas Christoph J. Binder Joseph L. Witztum | 2011 | Circulation Research2011，，2： | 1 |
| 5 | Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish 显示文摘 | Konstantin Stoletov Longhou Fang Soo-Ho Choi | 2009 | Circ Res2009，104，： | 1 |
| 6 | Ezetimibe and Simvastatin Reduce Cholesterol Levels in Zebrafish Larvae Fed a High-Cholesterol Diet显示文摘 | Ji Sun Baek Longhou Fang Andrew C. Li Yury I. Miller Jeffrey Cohn | 2012 | Cholesterol2012，，： | 1 |
| 7 | Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish显示文摘 | Konstantin Stoletov Longhou Fang Soo-Ho Choi Karsten Hartvigsen Lotte F. Hansen Chris Hall Jennifer Pattison Joseph Juliano Elizabeth R. Miller Felicidad Almazan Phil Crosier Joseph L. Witztum Richard L. Klemke Yury I. Miller | 2009 | Circulation Research2009，，8： | 1 |
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