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| 1 | Effect of different Io- dine nutrition on cerebellum Pcp-2 in rat offspring during lactation 显示文摘 | Zhang Lu Sun Yina Li Yongmei | 2011 | Biol Trace Elem Res2011，143，3： | 1 |
| 2 | Laboratory investigation of coal sample permeability under the coupled effect of temperature and stress显示文摘The stress and temperature sensitivities of coal reservoirs are critical geological factors affectingcoalbed methane(CBM)well exploitation;in particular it is important to reduce or eliminate their influence on coal reservoir permeability.To investigate coal permeability behavior at various effective stresses and temperatures,CH4 permeability tests were conducted on raw coal samples under a varying effective stress of 2.0-8.0 MPa under five different temperatures(25℃-65℃)in the laboratory.The results show that the permeability of the coal samples exponentially decreases with increasing effective stress or temperature,which indicates obvious stress and temperature sensitivity.Through a dimension-less treatment of coal permeability,effective stress,and temperature,a new stress sensitivity index S and tempera-ture index ST are proposed to evaluate coal stress and temperature sensitivity evaluation parameters.These new parameters exhibit integrality and uniqueness,and,in combination with stress sensitivity coefficient αk,tempe-rature sensitivity coefficient αT,and the permeability damage rate PDR,the sensitivities of coal permeability to stress and temperature are evaluated.The results indicate that coal sample stress sensitivity decreases with increasing effective stress,while it first decreases and then increases with increasing temperature.Additionally,coal sample temperature sensitivity shows a downward trend when temperature increases and fluctuates when effective stress increases.Finally,a coupled coal permeability model considering the impacts of effective stress and temperature is established,and the main factors affecting coal reservoir permeability and their control mechanism are explored.These results can provide some theoretical guidance for the further development of deep CBM. | Yina YU Zhaoping MENG Jiangjiang LI Yixin LU Caixia GAO | 2022 | Frontiers of Earth Science2022，16，4： | 1 |
| 3 | Early Diagnosis of Bipolar Disorder Coming Soon:Application of an Oxidative Stress Injury Biomarker(BIOS)Model显示文摘Early distinction of bipolar disorder(BD)from major depressive disorder(MDD)is difficult since no tools are available to estimate the risk of BD.In this study,we aimed to develop and validate a model of oxidative stress injury for predicting BD.Data were collected from 1252 BD and 1359 MDD patients,including 64 MDD patients identified as converting to BD from 2009 through 2018.30 variables from a randomly-selected subsample of 1827(70%)patients were used to develop the model,including age,sex,oxidative stress markers(uric acid,bilirubin,albumin,and prealbumin),sex hormones,cytokines,thyroid and liver function,and glycolipid metabolism.Univariate analyses and the Least Absolute Shrinkage and Selection Operator were applied for data dimension reduction and variable selection.Multivariable logistic regression was used to construct a model for predicting bipolar disorder by oxidative stress biomarkers(BIOS)on a nomogram.Internal validation was assessed in the remaining 784 patients(30%),and independent external validation was done with data from 3797 matched patients from five other hospitals in China.10 predictors,mainly oxidative stress markers,were shown on the nomogram.The BIOS model showed good discrimination in the training sample,with an AUC of 75.1%(95%CI:72.9%–77.3%),sensitivity of 0.66,and specificity of 0.73.The discrimination was good both in internal validation(AUC 72.1%,68.6%–75.6%)and external validation(AUC 65.7%,63.9%–67.5%).In this study,we developed a nomogram centered on oxidative stress injury,which could help in the individualized prediction of BD.For better real-world practice,a set of measurements,especially on oxidative stress markers,should be emphasized using big data in psychiatry. | Zhiang Niu Xiaohui Wu Yuncheng Zhu Lu Yang Yifan Shi Yun Wang Hong Qiu Wenjie Gu Yina Wu Xiangyun Long Zheng Lu Shaohua Hu Zhijian Yao Haichen Yang Tiebang Liu Yong Xia Zhiyu Chen Jun Chen Yiru Fang | 2022 | Neuroscience Bulletin2022，38，9： | 1 |
| 4 | Self-Assembled Porous-Reinforcement Microstructure-Based Flexible Triboelectric Patch for Remote Healthcare显示文摘Realizing real-time monitoring of physiological signals is vital for preventing and treating chronic diseases in elderly individuals. However,wearable sensors with low power consumption and high sensitivity to both weak physiological signals and large mechanical stimuli remain challenges.Here, a flexible triboelectric patch(FTEP) based on porous-reinforcement microstructures for remote health monitoring has been reported. The porousreinforcement microstructure is constructed by the self-assembly of silicone rubber adhering to the porous framework of the PU sponge. The mechanical properties of the FTEP can be regulated by the concentrations of silicone rubber dilution. For pressure sensing, its sensitivity can be effectively improved fivefold compared to the device with a solid dielectric layer, reaching 5.93 kPa^(-1) under a pressure range of 0–5 kPa. In addition, the FTEP has a wide detection range up to 50 kPa with a sensitivity of 0.21 kPa^(-1). The porous microstructure makes the FTEP ultra-sensitive to external pressure, and the reinforcements endow the device with a greater deformation limit in a wide detection range. Finally, a novel concept of the wearable Internet of Healthcare(Io H) system for real-time physiological signal monitoring has been proposed, which could provide real-time physiological information for ambulatory personalized healthcare monitoring. | Hao Lei Haifeng Ji Xiaohan Liu Bohan Lu Linjie Xie Eng Gee Lim Xin Tu Yina Liu Peixuan Zhang Chun Zhao Xuhui Sun Zhen Wen | 2023 | Nano-Micro Letters2023，15，7： | 0 |
| 5 | Survey and Analysis on Present Situation of Biological Experiment Teaching in Some Middle Schools in Yangjiang Area显示文摘Experimental teaching is an important part of biology teaching in middle school.In the form of questionnaire,this paper conducts a survey on some leading teachers of biology in the middle schools in the Yangjiang area about the biological experiment teaching in the implementation of the new curriculum,and analyzes the results of the survey.The problems and deficiencies in the implementation of biological experiment teaching in some middle schools in this area are found,and the relevant reform measures and suggestions are put forward in order to promote the better development of biological experiment teaching in middle schools. | Sainan LI Haoyao WU Yina LU Liping ZHOU | 2021 | Asian Agricultural Research2021，13，5： | 0 |
| 6 | Anti-inflammatory and Scalp Care Efficacy of a Multi-herb Extraction against Malassezia furfur显示文摘Malassezia furfur is a lipophilic and dermatological pathogenic yeast,which normally exists on human skin,and causes tinea versicolor,seborrhoeic dermatitis,and atopic dermatitis,especially on human scalp.The multi-herb extraction VGP which consists of Vitex trifolia fruit,Gentiana scabra,and Polygonum multiflorum root extract was used to study its effect of anti-inflammation,controlling sebum and dandruff on scalp care.Results showed that on the model of NHEK and THP1 cell inflammation induced by Malassezia furfur,VGP can inhibit the expression of interleukin 6(IL-6),prostaglandin E2(PGE-2),monocyte chemoattractant protein 1(MCP-1)and interleukin 1β(IL-1β)in a dose-dependent manner under 0.01%to 0.125%concentration.On the inflammatory model of 3D reconstructed skin induced by H2O2,VGP significantly improved the cell viability and skin structure,and reduced the production of interleukin 8(IL-8),PGE-2,and leukotriene B4(LTB4).During 4 week’s treatment with test shampoo contained 0.5%VGP thrice a week on 16 subjects met with different symptom,VGP reduced the sebum content and TEWL,improved the redness,itching and dandruff on human scalp skin.Therefore,as a natural active ingredient VGP can play a role in scalp care and skin care by targeting inflammation. | Lu Yina Jun Tian Wang Guoxun Liu Dong | 2020 | China Detergent & Cosmetics2020，5，4： | 0 |
| 7 | Research Progress on Nutritional Requirements of Carp显示文摘Carp is a temperate freshwater fish native to Asia,distributed in all regions of the world except Australia and South America.With the improvement of comprehensive and healthy breeding technology of carp,the unit yield has been greatly increased mainly due to the exten-sive use of compound feed.In this study,the nutritional requirements of carp were summarized from the aspects of protein,amino acids,fat,carbohydrate,calcium and phosphorus,vitamins and taurine.This study provides a certain theoretical reference for scientific formula of carp feed. | Yina LU | 2024 | Asian Agricultural Research2024，16，1： | 0 |
| 8 | Antibacterial,Anti-Keratinized and Anti-Inflammatory Effects of the GMP,A Multi-Herb Extraction on Acne Vulgaris显示文摘Recently reports showed that the pathobiology of acne vulgaris was arising from the exploration of sebaceous gland biology, hormonal factors, hyper-keratinization, and the role of bacteria, sebum, nutrition, cytokines and toll-like receptors (TLRs). Propionibacterium acnes (P.acnes) has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity on keratinocytes by acting on TLR-2, leads to the development of comedones. GMP, a multi-herb extraction, targeted most of the major pathogenic features of acne with desired physicochemical traits. It strongly suppressed P.acnes growth, and reduced inflammation by suppressing the TLR-2/NF- kB pathway in SZ-95 sebocytes and HaCaT keratinocytes. GMP exhibited a marginal effect on cell viability and may have modulated hyper-keratinization of the epidermis. These results demonstrate the clinical feasibility of applying GMP for the treatment of acne. | Lu Yina Wang Guangyin Xie Hong Tian Jun | 2018 | China Detergent & Cosmetics2018，3，4： | 0 |
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