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4篇 您的检索式:作者名="Lucas Friedman"
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1Can emergency physicians perform extended compression ultrasound for the diagnosis of lower extremity deep vein thrombosis?显示文摘BACKGROUND:Current point-of-care ultrasound protocols in the evaluation of lower extremity deep vein thrombosis (DVT) can miss isolated femoral vein clots.Extended compression ultrasound (ECUS) includes evaluation of the femoral vein from the femoral vein/deep femoral vein bifurcation to the adductor canal.Our objective is to determine if emergency physicians (EPs) can learn ECUS for lower extremity DVT evaluation after a focused training session.METHODS:Prospective study at an urban academic center.Participants with varied ultrasound experience received instruction in ECUS prior to evaluation.Two live models with varied levels of difficult sonographic anatomy were intentionally chosen for the evaluation.Each participant scanned both models.Pre-and post-study surveys were completed.RESULTS:A total of 96 ultrasound examinations were performed by 48 participants (11 attendings and 37 residents).Participants' assessment scores averaged 95.8% (95% CI 93.3%-98.3%) on the easier anatomy live model and averaged 92.3% (95% CI 88.4%-96.2%) on the difficult anatomy model.There were no statistically significant differences between attendings and residents.On the model with easier anatomy,all but 1 participant identified and compressed the proximal femoral vein successfully,and all participants identified and compressed the mid and distal femoral vein.With the difficult anatomy,97.9% (95% CI93.8%-102%) identified and compressed the proximal femoral vein,whereas 93.8% (95% CI 86.9%-100.6%) identified and compressed the mid femoral vein,and 91.7% (95% CI83.9%-99.5%) identified and compressed the distal femoral vein.CONCLUSION:EPs at our institution were able to perform ECUS with good reproducibility after a focused training session.Elaine Situ-LaCasse Helpees Guirguis Lucas Friedman Asad E.Patanwala Seth E.Cohen Srikar Adhikari 2019World Journal of Emergency Medicine2019,10,4:6
2Utility of point-of-care musculoskeletal ultrasound in the evaluation of emergency department musculoskeletal pathology显示文摘BACKGROUND: To evaluate the utilization of point-of-care ultrasound(POCUS) for the assessment of emergency department(ED) patients with musculoskeletal symptoms and the impact of musculoskeletal POCUS on medical decision-making and patient management in the ED.METHODS: This was a retrospective review of ED patients presenting with musculoskeletal symptoms who received a POCUS over a 3.5-year period. An ED POCUS database was reviewed for musculoskeletal POCUS examinations used for medical decision-making. Electronic medical records were then reviewed for demographic characteristics, history, physical examination findings, ED course, additional imaging studies, and impact of musculoskeletal POCUS on patient management in ED. RESULTS: A total of 264 subjects(92 females, 172 males) and 292 musculoskeletal POCUS examinations were included in the fi nal analysis. Most common symptomatic sites were knee(31.8%) and ankle(16.3%). Joint effusion was the most common fi nding on musculoskeletal POCUS, noted in 33.7% of the patients, and subcutaneous edema/cobblestoning was found in 10.2% of the patients. Muscle or tendon rupture was found in 2.3% of the patients, and 1.9% of the patients had joint dislocation. Bursitis or bursa fluid was found in 3.4% of patients, and tendonitis/tendinopathy was found in 2.3%. Twenty percent of them were ultrasound-guided musculoskeletal procedures, and most of them(73.3%) were arthrocentesis. Of the included studies, all except three either changed or helped guide patient management as documented in the patients' medical records.CONCLUSION: Our study fi ndings illustrate the utility of POCUS in the evaluation of a variety of musculoskeletal pathologies in the ED.Elaine Situ-LaCasse Ryan W. Grieger Stephen Crabbe Anna L. Waterbrook Lucas Friedman Srikar Adhikari 2018World Journal of Emergency Medicine2018,9,4:3
3Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals显示文摘Benjamin R. Carone Lucas Fauquier Naomi Habib Jeremy M. Shea Caroline E. Hart Ruowang Li Christoph Bock Chengjian Li Hongcang Gu Phillip D. Zamore Alexander Meissner Zhiping Weng Hans A. Hofmann Nir Friedman Oliver J. Rando 2010Cell2010,,7:1
4The Kruppel-Like Factor 6 Genotype Is Associated With Fibrosis in Nonalcoholic Fatty Liver Disease显示文摘Luca Miele Gary Beale Gillian Patman Valerio Nobili Julian Leathart Antonio Grieco Marilena Abate Scott L. Friedman Goutham Narla Elisabetta Bugianesi Christopher P. Day Helen L. Reeves 2008Gastroenterology2008,,1:1
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