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| 1 | Four Triterpene Oligoglycosides from the seeds of Aesculus Chinensis显示文摘A pair of novel geometrically isomeric triterpenoid saponins named escins IVa and IVb .together with known escins la and fo. were isolated from the seeds of Aesculus chinensis. Their structures were determined on the basis of spectroscopic evidences and comparison. | Jing ZHAO Xiu Wei YANG Yu Xin CUI Xue Hui LIU Shu Yan LIU Hong Ying ZHI Ji Yong CHEN Fa Bing ZHU Yun Li XUE and Dian Bo LIU (National Laboratory of Natural and Biomimetic Drugs, Beijing Medical University ,Beijing 1 00083)(Yantai Luye Pharmaceutical | 1999 | Chinese Chemical Letters1999,10,4: | 5 |
| 2 | Recent advances in two-photon imaging: technology developments and biomedical applications显示文摘In the past two decades, two-photon microscopy (TPM) transforms biomedicalresearch, allowing nondestructive high-resolution fluorescent molecular imaging and label-free imaging in vivo and in real time. Here we review the recent advances of TPM technologyincluding novel laser sources, new image acquisition paradiams, and microendoscopicimaging systems. Then, we survey the capabilities of TPM imagingof biological relevant molecules such as nicotinamideadenine dinucleotide (NADH), flavin adenine dinucleotide (FAD),and reactive oxygen species (ROS). Biomedical applications of TPM in neuroscience and cancer detection are demonstrated. | Yu Chen Hengchang Guo Wei Gong Luye Qin Hossein Aleyasin Rajiv R Ratan Sunghee Cho Jianxin Chen Shusen Xie | 2013 | Chinese Optics Letters2013,11,1: | 2 |
| 3 | The draft genome of the fast-growing non-timber forest species moso bamboo (PhyUostachys heterocycla) 显示文摘 | Peng Z H Lu Y Li L Zhao Q Feng Q Gao Z M Lu H Y Hu T YAO N Liu K Y LiY FanDL GuoYL LiW J LuY Q Weng Q J Zhou C C Zhang L Huang T Zhu C R Liu X G Yang X W Wang T Miao K Zhuang C Y Cao X L Tang W L Liu G S Liu Y L Chen J Liu Z J Yuan L C Liu Z H Huang X H LuT T Fei B H Ning Z M Han B Jiang Z H | 2013 | Nature Genetics2013,45,4: | 1 |
| 4 | Role of hydroxyl radical in silicainduced NF- kappa B activation in macrophages显示文摘 | CHEN F LUY DEMERS LM | 1998 | Ann Clin Lab Sci1998,28,1: | 1 |
| 5 | A self-organizing fuzzy sliding mode controller design for aclass of nonlinear servo systems显示文摘 | Chen J S | 1994 | IEEE Tram Industrial Electrial Electronics1994,41,5: | 1 |
| 6 | Stainless steel cloth modified by carbon nanoparticles of Chinese ink as scalable and high-performance anode in microbial fuel cell显示文摘Microbial fuel cells(MFCs) have various potential applications.However,anode is a main bottleneck that limits electricity production performance of MFCs.Herein,we developed a novel anode based on a stainless steel cloth(SC) modified with carbon nanoparticles of Chinese ink(Cl) using polypyrrole(PPy)as a building block(PPy/Cl/SC).After modification,PPy/Cl/SC showed a 30% shorten in start-up time(36.4 ± 3.3 h vs.52.3± 1.8 h),33% increase in the maximum current(12.4 ± 1.4 mA vs.9.3± 0.95 mA),and2.3 times higher in the maximum power density of MFC(61.9 mW/m^(2) vs.27.3 mW/m^(2)),compared to Ppy/SC.Experimental results revealed that carbon nanoparticles were able to cover SC uniformly,owing to excellent dispersibility of carbon nanoparticles in Cl.The attachment of carbon nanoparticles formed a fluffy layer on SC increased the electrochemically-active surface area by 1.9 times to 44.5 cm^(2).This enhanced electron transfer between the electrode and bacteria.Further,embedding carbon nanoparticles into the PPy layer significantly improved biocompatibility as well as changed functional group contents,which were bene ficial to bacteria adhesion on electrodes.Taking adva ntage of high mechanical strength and good conductivity,a large-size PPy/Cl/SC was successfully prepared(50×60 cm^(2))demonstrating a promising potential in practical applications.This simple fabrication strategy offers a new idea of developing low cost and scalable electrode materials for high-performance energy harvesting in MFCs. | Haoliang Wu Hao Tan Luye Chen Bin Yang Yang Hou Lecheng Lei Zhongjian Li | 2021 | Chinese Chemical Letters2021,32,8: | 0 |
| 7 | Antioxidant response to severe hypoxia in Brandt’s vole Lasiopodomys brandtii显示文摘The antioxidant defense system is essential for animals to cope with homeostasis disruption and overcome oxidative stress caused by adverse environmental conditions such as hypoxia.However,our understanding of how this system works in subterranean rodents remains limited.In this study,Brandt’s vole Lasiopodomys brandtii was exposed to normoxia(21%O_(2))or hypoxia(mild or severe hypoxia:10%or 5%O_(2))for 6 h.Changes in key enzymes of the classic enzymatic antioxidant system at both mRNA and enzyme activity levels,and tissue antioxidant levels of the low-molecular-weight antioxidant system were determined in brain,liver,and kidney.Transcript levels of the upstream regulator NF-E2-related factor 2(Nrf2)were also measured.We found that the mRNA expression of Nrf2 and its downstream antioxidant enzyme genes in L.brandtii were relatively conserved in response to hypoxia in most tissues and genes tested,except in the liver.Hepatic Nrf2,Cu/Zn SOD,GPx1,and GPx3 levels were significantly upregulated in response to mild hypoxia,whereas Mn SOD level decreased significantly in severe hypoxia.Unmatched with changes at the RNA level,constitutively high and relatively stable antioxidant enzyme activities were maintained throughout.For the low-molecular-weight antioxidant system,an abrupt increase of cerebral ascorbic acid(AA)levels in hypoxia indicated a tissue-specific antioxidant response.Although hypoxia did not cause significant oxidative damage in most tissues tested,the significant decrease in antioxidant enzyme activities(GPX and GR)and increase in lipid peroxidation in the kidney suggest that prolonged hypoxia may pose a critical threat to this species. | Luye SHI Bojian CHEN Xinrui WANG Maolin HUANG Congcong QIAO Jingou WANG Zhenlong WANG | 2022 | Integrative Zoology2022,17,4: | 0 |