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| 1 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 2 | Mathematical simulation of radial heat transfer in packed beds by pseudohomogeneous modeling显示文摘Uniform flow regime and constant effective thermal conductivity inside packed beds are commonly accepted in the evaluation of the fluid dynamics and heat transfer in such systems.However,several authors have confirmed the presence of an oscillatory velocity profile caused by the effective contribution of porosity profile in the fluid dynamic behavior of packed beds,which directly influences the heat transfer inside the beds.This paper describes the application of a pseudo-homogeneous mathematical model for describing heat transfer in packed beds with oscillatory profiles of velocity and porosity,using a radius-dependent model for effective thermal conductivity k r.Several temperature profiles were obtained in a packed bed system with thermal source located on the wall.The simulated temperature and effective thermal conductivity obtained from simulations were compared with experimental data and calculation from a model based on uniform k r fitting.The results indicate that the proposed mathematical modeling was capable of better representing the heat transfer in the packed bed. | Rodrigo Béttega Marcos Flávio Pinto Moreira Ronaldo Guimaraes Corrêa José Teixeira Freire | 2011 | Particuology2011，9，2： | 2 |
| 3 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 4 | Immediate and late effects of chronic stress in the testes of prepubertal and adult rats显示文摘这研究的目的是在 prepubertal 和成年老鼠的睾丸上调查长期的应力的效果并且评估任何改变是否能被颠倒什么时候强调正式就职被结束。老鼠被分到八的 76 男性组织取决于处理的类型(控制或强调) ,应力在被开始的年龄(prepubertal 或成年人) ,和评估的时间(立即或迟了) 。压力刺激 6 个星期被申请。在最后压力刺激以后立即评估的强调 prepubertal 和成年老鼠分别地在 SP-I 和 SA-I 组被包括。迟了的 prepubertal (系统程序设计语言) 和成年人(柳安) 强调老鼠组织 6 个星期在最后压力刺激以后被评估。匹配年龄的老鼠被用作控制(CP-I, CA-I, CP-L,和 CA-L 组) 。到在 SP-I 组的老鼠的压力刺激的申请导致了身体重量和生精的小管直径减小。在 SA-I 组的老鼠也显示出几功能(睾丸激素水平和精子参数) 并且词法(阴囊的重量和生精的小管直径) 减小。在系统程序设计语言组的老鼠显示出增加的身体重量和 intertubular 分隔空间容量、绝对的密度和减少的管状的分隔空间容量的密度。在柳安组的老鼠介绍了仅仅减少的精子生存能力。压力刺激在所有学习组在老鼠支持了变化。成年老鼠的睾丸是长期的应力影响的大多数。然而,强调成年老鼠从阴囊的改变恢复了很好。 | Carina T Ribeiro Diogo B De Souza Waldemar S Costa Francisco J B Sampaio Marco A Pereira-Sampaio | 2018 | Asian Journal of Andrology2018，20，4： | 2 |
| 5 | Functional effects of high clopi- dogrel maintenance dosing in patients with inadequate platelet inhibition on standard dose treatment显示文摘 | Dominick J Marco A Steven B | 2008 | Am J Cardiol2008，101，： | 1 |
| 6 | Biotransformation of α-,β-,γ-,and δ-Hexachlorocyclohexane Under Methanogenic Conditions显示文摘 | MIDDELDORP P J M MARCO J ZEHNDER A J B | 1996 | Environmental Science & Technology1996，30，7： | 1 |
| 7 | Bcl - 2 family gene modulation during spontaneous apoptosis of B- chronic lymphocytic leukemia 显示文摘 | SANZ L MARCO J A CASANOVA B | 2004 | Biochem Biophys RES C~mmun2004，315，3： | 1 |
| 8 | Response surface methodology (RSM) as a tool for optimization in ana- lytical chemistry显示文摘 | MARCOS A B RICARDO E S ELIANE P 0 | 2008 | Talanta2008，76，5： | 1 |
| 9 | SecLEACH--on the Security of Clustered Sensor Networks显示文摘 | Oliveira L B Marco A F | 2007 | Signal Processing2007，87，12： | 1 |
| 10 | Muhifocal papillary thyroid carcinoma associated with primary amyloid goiter显示文摘 | COCA- PELAZ A VIVANCO- ALLENDE B ALVAREZ- MARCOS C | 2012 | Auris Nasus Larynx2012，39，5： | 1 |
| 11 | Influence of HPP conditions on selected beef quality attributes and their stability during chilled storage 显示文摘 | McArdle R A Marcos B Kerry J P | 2011 | Meat Science2011，87，3： | 1 |
| 12 | Orally Active Purine-Based Inhibitor of the Heat Shock Protein 90 显示文摘 | Marco A B Jiandong S Kevin H | 2006 | J Med Chem2006，49，： | 1 |
| 13 | Response surface methodology ( RSM ) as a tool for optimization in analytical chemistry 显示文摘 | Marcos A B Ricardo E S Eliane P O | 2008 | Talanta2008，，76： | 1 |
| 14 | Seed rain and seed limitation in a planted gallery forest in Brazil 显示文摘 | Karina C B Marco A P | 2006 | Restoration Ecology2006，14，4： | 1 |
| 15 | Role of mast cells and pro-inflammatory mediators on the intestinal secretion induced by cholera toxin显示文摘 | Marcos F.G Rocha José E.P Aguiar José J.C Sidrim Raimundo B Costa Regina F.G Feitosa Ronaldo A Ribeiro Aldo A.M Lima | 2003 | Toxicon2003，，2： | 1 |
| 16 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 17 | Thtee dimensional computed tomographic angiography in detection of cerebral aneurysms in acute subaraehnoid morrhage显示文摘 | Zouaoui A Sahel M Marco B | 1997 | Neurosurgery1997，41，： | 1 |
| 18 | High pressure induced changes on sarcoplasmic protein fraction and quality indicators显示文摘 | Marcos B Kerry J P Mullen A M | 2010 | Meat Science2010，，85： | 1 |
| 19 | Pyrolysis of municipal plastic wastes: Influence of raw material composition 显示文摘 | Lopez A de Marco I Caballero B M | 2010 | Waste Management2010，30，4： | 1 |
| 20 | Pyrolysis of Plastic Packaging Waste : A Comparison of Plastic Residuals from Material Recovery Facilities with Simulated Plastic Waste显示文摘 | Adrados A Marco I Caballero B M | 2011 | Waste Management2011，，： | 1 |
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