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| 1 | Structural insights of phosphorylated into the recognition FUNDC1 by LC3B in mitophagy显示文摘 | Mengqi Lv Chongyuan Wang Fudong Li Junhui Peng Bin Wen Qingguo Gong Yunyu Shi Yajun-Tang | 2017 | Protein & Cell2017，8，1： | 21 |
| 2 | Effect of Cyclocarya paliurus polysaccharides on streptozotocin-induced diabetic nephropathy in rats显示文摘OBJEVTIVE:To investigate the efficacy of Cyclocarya paliurus(C.paliurus)polysaccharides on streptozotocin-induced diabetic nephropathy in rats.METHODS:Rats were divided into 6 groups,including group of normal control,group of diabetic control,group of metformin treatment,low-dose group of C.paliurus polysaccharides treatment,middle-dose group of C.paliurus polysaccharides treatment and high-dose group of C.paliurus polysaccharides treatment.Histological analysis of kidney was analyzed using hematoxilin and eosin.Levels of blood glucose,creatinine,urea,uric acid were determined by spectrophotometry.Anti-oxidative enzymes were measured by real-time polymerase chain reaction(PCR)and enzyme-linked immunosorbent assay(ELISA).Advanced glycation end products(AGEs)and transforming growth factor-β1(TGF-β1)level was measured by ELISA.RESULTS:Abnormal changes were observed in the group of diabetic control characterized by atrophy of the renal glomeruli with hypercellularity,congestion of glomerular tufts,dilation of the renal spaces,and degeneration of renal tubule.Compared with that of normal group,blood glucose,creatinine,urea,uric acid level was significantly increased in the group of diabetic control.Superoxide dismutase,catalase,glutathione peroxidase,glutathione reductase level was significantly decreased,but AGEs and TGF-β1 level was significantly increased.By contrast,administration of C.paliurus polysaccharides and metformin could reverse the above-mentioned results of the group of diabetic control,especially in the high-dose group of C.paliurus polysaccharides.CONCLUSION:Our findings suggest that C.paliurus polysaccharides may play a protecting role for nephropathy of diabetic rats by lowering glucose,creatinine,urea,uric acid level,enhancing the antioxidative ability,and reducing AGEs and TGF-β1 expression. | Xia Xichao Mao Dongxue Dai Hongmei Wu Xi Zhang Zuyuan Wang Huaying Zhou Wenwen Dong Yanmei Wang Mengqi Li Yuan Shao Xiangyang Ouyang Jingfeng | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 9 |
| 3 | How do Chinese medicines that tonify the kidney inhibit dopaminergic neuron apoptosis?显示文摘Wistar rats were intragastrically perfused with Chinese medicines used for tonifying the kidney.These included 0.180 g/mL of Herba Epimedii(Epimedium), Semen Cuscutae(Dodder Seed), or Herba Cistanches(Desertliving Cistanche), 0.04 mg/mL monoamine oxidase-B inhibitor selegiline,or distilled water for 14 consecutive days to prepare drug-containing serum or blank serum.MES23.5 cells in the logarithmic phase were cultured in media supplemented with 15%drug-containing serum for 24 hours, followed by incubation in culture solution containing 100 μmol/L H2O2for 3 hours. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) and flow cytometry results showed that all drug-containing serums improved the survival rate of H2O2-injured MES23.5 cells, inhibited pro-apoptotic FasL and caspase-3 expression, promoted anti-apoptotic Bcl-2 expression. However, drug-containing serums had little influence on Fas expression in H2O2-injured MES23.5 cells. Enzyme-linked immunosorbent assay results showed that serum containing Herba Cistanches or Herba Epimedii increased the expression of nerve growth factor,brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in injured MES23.5cells; serum containing Semen Cuscutae only increased brain-derived neurotrophic factor expression; while expression of the above neurotrophic factors remained the same in cells treated with serum containing selegiline. These findings indicate that Chinese medicines used to tonify the kidney can protect nerve cells by regulating the expression of apoptosis-related factors and neurotrophic factors in MES23.5 cells. | Shaogang Lin Shuifen Ye Jinmu Huang Yun Tian Yihui Xu Mengqi Wu Jingxia Wang Songying Wu Jing Cai | 2013 | Neural Regeneration Research2013，8，30： | 9 |
| 4 | Arabidopsis CNGC14 Mediates Calcium Influx Required for Tip Growth in Root Hairs显示文摘 | Sisi Zhang Yajun Pan Wang Tian Mengqi Dong Huifen Zhu Sheng Luan Legong Li | 2017 | Molecular Plant2017，10，7： | 8 |
| 5 | Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress显示文摘AMPK, a master regulator of metabolic homeostasis, is activated by both AMP-dependent and AMP-independent mechanisms. The conditions under which these different mechanisms operate, and their biological implications are unclear. Here, we show that, depending on the degree of elevation of cellular AMP, distinct compartmentalized pools of AMPK are activated, phosphorylating different sets of targets. Low glucose activates AMPK exclusively through the AMP-independent, AXIN-based pathway in lysosomes to phosphorylate targets such as ACC1 and SREBP1c, exerting early anti-anabolic and pro-catabolic roles. Moderate increases in AMP expand this to activate cytosolic AMPK also in an AXIN-dependent manner. In contrast, high concentrations of AMP, arising from severe nutrient stress, activate all pools of AMPK independently of AXIN. Surprisingly, mitochondrion-localized AMPK is activated to phosphorylate ACC2 and mitochondrial fission factor (MFF) only during severe nutrient stress. Our findings reveal a spatiotemporal basis for hierarchical activation of different pools of AMPK during differing degrees of stress severity. | Yue Zong Chen-Song Zhang Mengqi Li Wen Wang Zhichao Wang Simon A. Hawley Teng Ma Jin-Wei Feng Xiao Tian Qu Qi Yu-Qing Wu Cixiong Zhang Zhiyun Ye Shu-Yong Lin Hai-Long Piao D. Grahame Hardie Sheng-Cai Lin | 2019 | Cell Research2019，29，6： | 8 |
| 6 | Analyses of oligodontia phenotypes and genetic etiologies显示文摘Oligodontia is the congenital absence of six or more teeth and comprises the more severe forms of tooth agenesis.Many genes have been implicated in the etiology of tooth agenesis,which is highly variable in its clinical presentation.The purpose of this study was to identify associations between genetic mutations and clinical features of oligodontia patients.An online systematic search of papers published from January 1992 to June 2021 identified 381 oligodontia cases meeting the eligibility criteria of causative gene mutation,phenotype description,and radiographic records.Additionally,ten families with oligodontia were recruited and their genetic etiologies were determined by whole-exome sequence analyses.We identified a novel mutation in WNT10A(c.99_105dup)and eight previously reported mutations in WNT10A(c.433 G>A;c.682 T>A;c.318 C>G;c.511.C>T;c.321 C>A),EDAR(c.581 C>T),and LRP6(c.1003 C>T,c.2747 G>T).Collectively,20 different causative genes were implicated among those 393 cases with oligodontia.For each causative gene,the mean number of missing teeth per case and the frequency of teeth missing at each position were calculated.Genotype–phenotype correlation analysis indicated that molars agenesis is more likely linked to PAX9 mutations,mandibular first premolar agenesis is least associated with PAX9 mutations. | Mengqi Zhou Hong Zhang Heather Camhi Figen Seymen Mine Koruyucu Yelda Kasimoglu Jung-Wook Kim Hera Kim-Berman Ninna M.R.Yuson Paul J.Benke Yiqun Wu Feng Wang Yaqin Zhu James P.Simmer Jan C-C.Hu | 2021 | International Journal of Oral Science2021，13，3： | 5 |
| 7 | Are foreign monks better at chanting? The effect of ‘airborne’ SDICs on anti-corruption显示文摘The independence of supervision agency is of great importance for anti-corruption.After the leadership transition of the provincial Congress of the Chinese Communist Party in 2006,Secretaries of Discipline Inspection Commission(SDICs)were suddenly dispatched from the centre or transferred from another province in China(‘airborne’SDICs)to enhance their independence in inspecting corruption cases.To investigate the effect of this policy reform,we collect data of SDICs and anti-corruption in 31 provinces from 2003 to 2014,and evaluate this policy using the difference-in-differences econometrics method.We find that there is no significant effect of these‘airborne’SDICs whether from the centre or another province on anti-corruption.This result is robust to different measurements of anti-corruption and subsamples.We argue that the dispatch of external SDICs is not enough to ensure the independence of supervision agency,because local discipline inspection commissions(DICs)are still subject to local Chinese Communist Party committees in terms of personnel,funds and property.This paper has important policy implications for the current anti-corruption campaign in China. | Huihua Nie Mengqi Wang | 2016 | Economic and Political Studies2016，4，1： | 4 |
| 8 | 羟基磷灰石负载金催化丙酮醇与甲醇氧化酯化合成丙酮酸甲酯:酸碱性质的基本作用(英文)显示文摘丙酮醇是一种可由木质纤维素类生物质经分步或快速热裂解获得的主要轻质含氧化合物.本文报道了金基催化剂上,丙酮醇可经氧化酯化反应被选择性转化为重要的精细化学品--丙酮酸甲酯.研究结果表明具有适宜强度和比例酸碱位点的两性载体负载金催化剂能够促进氧化酯化反应进行,同时不加快羟醛缩合缩合和Cannizzaro反应等副反应进行.其中,羟基磷灰石(钙磷比为1.62)负载金催化剂上,丙酮醇转化率为62%,丙酮酸甲酯选择性可达87%. | Yan Wan Congcong Zheng Xianchi Lei Mengqi Zhuang Jinhan Lin Wenda Hu Jing dongLin Shaolong Wan Yong Wang | 2019 | Chinese Journal of Catalysis2019，40，11： | 3 |
| 9 | Infection and Colonization of Pathogenic Fungus Fusarium proliferatum in Rice Spikelet Rot Disease显示文摘Rice spikelet rot disease(RSRD), caused by Fusarium proliferatum, is an emerging disease. So far, the effects of diseased rice floral organs as well as the primary infection sites and stages of this pathogen are not determined. We investigated changes in the floral organs, along with the infection processes of the pathogen in plants inoculated with F. proliferatum and labelled with a green fluorescent protein during different growth stages of rice. The results showed that RSRD is not a systemic infectious disease, which has negative effects on the fertility of the infected rice. F. proliferatum caused brown colored anthers, crinkled pistils and ovaries, pollen grain deformities and anther indehiscence. The number of pollen grains on the stigmas decreased significantly in the infected spikelets, and the anther dehiscence and seed-setting rate successively declined by 69% and 73%, respectively, as a result of the infection. The initial infection stage occurred at the pollen cell maturity stage, and the primary invasion sites were determined to be the anthers of rice. It was noted that the pathogen mainly damaged the pollen cells, and with the exception of the filaments, proceeded to colonize the pistils and endosperm. | SUN Lei WANG Ling LIU Lianmeng HOU Yuxuan XU Yihua LIANG Mengqi GAO Jian LI Qiqin HUANG Shiwen | 2019 | Rice science2019，26，1： | 3 |
| 10 | Temperature dependent conductivity of Bi_4Ti_3O_(12) ceramics induced by Sr dopants显示文摘Bi_4Ti_3O_(12) is an important lead-free ferroelectric material.Doping modification of Bi_4Ti_3O_(12)has attracted great attention to improving its performances.In this work,the effect of Sr dopants on the microstructure,dielectric,and conductivity of Bi_4Ti_3O_(12) ceramic was investigated by XRD,SEM,and AC impedance spectroscopy.Substitution of 1 at%Sr for Bi decreased the grain size,suppressed the dielectric dispersion of Bi_4Ti_3O_(12) ceramic at room temperature,and resulted in different effects on the conductivity of grains and grain boundaries.The conductivity of grains in Bi_4Ti_3O_(12) ceramic was increased by the small amount of Sr dopants in the whole experimental temperature range.While the grain boundaries of 1 at%Sr-doped Bi_4Ti_3O_(12) exhibited lower conductivity than pure Bi_4Ti_3O_(12) below~380℃and higher conductivity above~380℃.The experimental phenomena were interpreted in term of compensating defects for Sr dopants. | Lin WANG Mengqi GUI Hai-Bo JIN Xinyuan HU Yongjie ZHAO Naseer Muhammad ADNAN Jing-Bo LI | 2018 | Journal of Advanced Ceramics2018，7，3： | 3 |
| 11 | The interaction of CaM7 and CNGC14 regulates root hair growth in Arabidopsis显示文摘Oscillations in cytosolic free calcium determine the polarity of tip-growing root hairs.The Ca2+channel cyclic nucleotide gated channel 14(CNGC14)contributes to the dynamic changes in Ca^2+concentration gradient at the root hair tip.However,the mechanisms that regulate CNGC14 are unknown.In this study,we detected a direct interaction between calmodulin 7(CaM7)and CNGC14 through yeast two-hybrid and bimolecular fluorescence complementation assays.We demonstrated that the third EF-hand domain of CaM7 specifically interacts with the cytosolic C-terminal domain of CNGC14.A two-electrode voltage clamp assay showed that CaM7 completely inhibitsCNGC14-mediated Ca2+influx,suggesting that CaM7 neg-atively regulates CNGC14-mediated calcium signaling.Fur-thermore,CaM7 overexpressing lines phenocopy the short root hair phenotype of a cngc14 mutant and this phenotype is insensitive to changes in external Ca^2+concentrations.We,thus,identified CaM7-CNGC14 as a novel interacting module that regulates polar growth in root hairs by con-trolling the tip-focused Ca2+signal. | Qudsia Zeb Xiaohan Wang Congcong Hou Xiwen Zhang Mengqi Dong Sisi Zhang Qian Zhang Zhijie Ren Wang Tian Huifen Zhu Legong Li Liangyu Liu | 2020 | Journal of Integrative Plant Biology2020，62，7： | 3 |
| 12 | GCN2 deficiency protects mice from denervation-induced skeletal muscle atrophy via inhibiting FoxO3a nuclear translocation显示文摘 | Yuting Guo Huiwen Wang Yinglong Tang Yue Wang Mengqi Zhang Zhiguang Yang Eric Nyirimigabo Bin Wei Zhongbing Lu Guangju Ji | 2018 | Protein & Cell2018，9，11： | 3 |
| 13 | Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats显示文摘OBJEVTIVE:To investigate the effects of Cyclocarya paliurus(C.paliurus)polysaccharides on the spleen injury of diabetic rats.METHODS:Animals were divided into 6 groups,including normal group,model group,control group,low-dose group of C.paliurus polysaccharides treatment,middle-dose group of C.paliurus polysaccharides treatment and high-dose group of C.paliurus polysaccharides treatment.Histological analysis of spleen was analyzed using hematoxilin and eosin.Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry.Interleukin-7(IL-7)and IL-10 were measured by enzyme-linked immunosorbent assay.RESULTS:Compared with that of model group,superoxide dismutase,catalase,glutathione peroxidase,glutathione reductase level increased 78.63%(P<0.05),51.76%(P<0.05),2.95 times(P<0.01)and 41.11%(P<0.05)in the high-dose group of C.paliurus polysaccharides treatment,respectively.IL-7 and IL-10 increase 1.66(P<0.01)and 1.21 times(P<0.01)in the high-dose group of C.paliurus polysaccharides treatment,respectively.CONCLUSION:It is suggested that C.paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. | XIA Xichao LI Bin QIU Ju TIAN Gang CHEN Changdong LA Ming ZHANG Ke QI Jinxu LI Yanyan GAO Huashan SHAO Xiangyang SU Congying WANG Mengqi OUYANG Jingfeng | 2021 | Journal of Traditional Chinese Medicine2021，41，5： | 2 |
| 14 | Operation Efficiency and Influencing Factors of Listed Companies of Swine Industry:Empirical Analysis Based on Data of 16 Listed Companies in 2010-2014显示文摘Listed companies of the swine industry,as an important form of agricultural industrialized operation,are typical representatives of large-scale production and the level of their operation efficiency exerts a direct influence on the healthy development of the swine industry.Using the DEA-based Malmquist method,this paper made a static and dynamic evaluation of the operation efficiency of 16 listed companies in China's swine industry in 2010-2014. It obtained following results:( i) The overall efficiency of listed companies of China's swine industry remained at high level and the development trend was excellent.( ii) Different types of enterprises had difference in the overall efficiency,pure technical efficiency and scale efficiency. In general,pig feed processing companies had the best performance,followed by slaughtering and deep processing companies,and swine breeding companies were the worst.( iii) The total factor productivity characterized by the Malmquist index declined year by year in 2010-2013 and was improved in 2014,mainly due to technological progress.( iv) The total asset turnover ratio,equity concentration,and R & D management level had a significantly positive impact on the operation efficiency of listed companies in the swine industry,while the human capital had a significantly negative impact. | Mengqi YOU Zhenhong QI Ai’e WANG Xinrui LI Weihong HUANG Wenbin WAN | 2017 | Asian Agricultural Research2017，9，3： | 2 |
| 15 | The performance and mechanism of iron-mediated chemical oxidation:Advances in hydrogen peroxide,persulfate and percarbonate oxidation显示文摘Many studies have successfully built iron-mediatedmaterials to activate or catalyze Fentonlike reactions,with applications in water and wastewater treatment being investigated.However,the developed materials are rarely compared with each other regarding their performance of organic contaminant removal.In this review,the recent advances of Fentonlike processes in homogeneous and heterogeneous ways are summarized,especially the performance and mechanism of activators including ferrous iron,zero valent iron,iron oxides,iron-loaded carbon,zeolite,and metal organic framework materials.Also,this work mainly compares three O-O bond containing oxidants including hydrogen dioxide,persulfate,and percarbonate,which are environmental-friendly oxidants and feasible for in-situ chemical oxidation.The influence of reaction conditions,catalyst properties and benefits are analyzed and compared.In addition,the challenges and strategies of these oxidants in applications and the major mechanisms of the oxidation process have been discussed.This work can help understand the mechanistic insights of variable Fenton-like reactions,the role of emerging iron-based materials,and provide guidance for choosing appropriate technologies when facing real-world water and wastewater applications. | Mengqi Han Hui Wang Wei Jin Wenhai Chu Zuxin Xu | 2023 | Journal of Environmental Sciences2023，，6： | 2 |
| 16 | Analysis of TM/TE mode enhancement and droop reduction by a nanoporous n-AIGaN underlayer in a 290 nm UV-LED显示文摘A full structure 290 nm ultraviolet light emitting diode(UV-LED)with a nanoporous n-AlGaN underlayer was fabricated by top via hole formation followed by high-voltage electrochemical etching.The 20 to 120 nm nanopores were prepared in regular doped n-AlGaN by adjusting the etching voltage.The comparison between the Raman spectrum and the photoluminescence wavelength shows that the biaxial stress in the nanoporous material is obviously relaxed.The photoluminescence enhancement was found to be highly dependent on the size of the pores.It not only improves the extraction efficiency of top-emitting transverse-electric(TE)-mode photons but also greatly improves the efficiency of side emitting tran sverse-magnetic(TM)-mode photons.This leads to the polarization change of the side-emitting light from-0.08 to-0.242.The intensity of the electroluminescence was increased by 36.5%at 100 mA,and the efficiency droop at high current was found to decrease from 61%to 31%. | YUFENG LI CHENYU WANG YE ZHANG PENG HU SHENGNAN ZHANG MENGQI DU XILIN SU QIANG LI FENG YUN | 2020 | Photonics Research2020，8，6： | 2 |
| 17 | Deep Learning Predicts Stress–Strain Relations of Granular Materials Based on Triaxial Testing Data显示文摘This study presents an AI-based constitutive modelling framework wherein the prediction model directly learns from triaxial testing data by combining discrete element modelling(DEM)and deep learning.A constitutive learning strategy is proposed based on the generally accepted frame-indifference assumption in constructing material constitutive models.The low-dimensional principal stress-strain sequence pairs,measured from discrete element modelling of triaxial testing,are used to train recurrent neural networks,and then the predicted principal stress sequence is augmented to other high-dimensional or general stress tensor via coordinate transformation.Through detailed hyperparameter investigations,it is found that long short-term memory(LSTM)and gated recurrent unit(GRU)networks have similar prediction performance in constitutive modelling problems,and both satisfactorily predict the stress responses of granular materials subjected to a given unseen strain path.Furthermore,the unique merits and ongoing challenges of data-driven constitutive models for granular materials are discussed. | Tongming Qu Shaocheng Di Y.T.Feng Min Wang Tingting Zhao Mengqi Wang | 2021 | Computer Modeling in Engineering & Sciences2021，，7： | 2 |
| 18 | The prognostic value of programmed cell death ligand 1expression in non-Hodgkin lymphoma:a meta-analysis显示文摘Objective: Although the prognostic value of programmed cell death-ligand 1(PD-L1) expression in non-Hodgkin lymphoma(NHL) has been evaluated in many studies, the results remain controversial. To investigate the prognostic role of PD-L1 expression and the association between PD-L1 expression and clinicopathological features of NHL, we performed a meta-analysis.Methods: The Pub Med, EMBASE, and Cochrane Library databases were searched up to November 30, 2017. The hazard ratio(HR), 95% confidence interval(CI), and odds ratios(OR) with 95% CIs were combined to evaluate the association of PD-L1 expression with overall survival(OS) and clinicopathological features. Review manager 5.3 and STATA 12.0 were used in this meta-analysis.Results: A total of 2,005 patients across nine studies were enrolled in our meta-analysis, and the pooled results showed that high PD-L1 expression was associated with a poor prognosis(HR=2.04, 95% CI: 1.18–3.54, P=0.01). In the subgroup analysis according to histology types, pooled results demonstrated that an increased PD-L1 expression was an unfavorable prognostic factor for diffuse large B-cell lymphoma(HR=1.92, 95% CI: 1.06–3.48, P=0.03) but not for natural killer/T-cell lymphoma(HR=2.41, 95%CI: 0.47–12.22, P=0.29). Pooled ORs indicated that PD-L1 expression was higher in NHL with international prognostic indices of≥3. However, PD-L1 expression had no correlation with gender, age, disease stage, lactate dehydrogenase level, B symptoms, and germinal center B-cell-like lymphoma.Conclusions: High PD-L1 expression was a poor prognostic biomarker in patients with NHL. Because of our limited sample size,high-quality studies with larger sample sizes are needed to validate our results. | Shu Zha Minghui Zhang Yu Zhang Hongxue Meng Yan Wang Yupeng Liu Jing Jing Lan Huang Mengqi Sun Yue Zhang Qingyuan Zhang | 2018 | Cancer Biology & Medicine2018，15，3： | 2 |
| 19 | A New Indicator for Global Food Security Assessment: Harvested Area Rather Than Cropland Area显示文摘Cropland area has long been used as a key indicator of food security.However,grain yield is not solely controlled by the area of the cropland.Therefore,we proposed a new indicator to assess food security.Results show that from 1992 to 2004,the global cropland area increased by 840200 km^(2)(99.4%),but the grain yield increased only by 310 million t(29.1%);and from 2004 to 2015,the cropland area decreased by 39000 km^(2)(4.64%),but the grain yield increased by 370 million t(70.84%).This result showed that grain yield was not linearly correlated with cropland area,and delimiting the threshold of cropland protection may not guarantee food security.Combined with further correlation analysis,we found that the increase in the global grain yield was more closely related to the harvested area(R^(2)=0.94),which indicated that the harvested area is a more scientific and accurate indicator than cropland area in terms of guaranteeing food security.Therefore,if governments want to ensure the food security,they should choose a new and more accurate indicator:harvested area rather than cropland area. | SONG Fengjiao WANG Shijie BAI Xiaoyong WU Luhua WANG Jinfeng LI Chaojun CHEN Huan LUO Xuling XI Huipeng ZHANG Sirui LUO Guofeng YAN Mengqi ZHEN Qingqing | 2022 | Chinese Geographical Science2022，32，2： | 2 |
| 20 | Is the neocortex a novel reservoir for adult mammalian neurogenesis?显示文摘A novel population of cells expressing typical markers of immature neurons,such as doublecortin-positive cells,was recently identified.This population was predominantly located in layer II of the adult cerebral cortex of relatively large mammals.These cells appear to maintain an immature phenotype for a protracted time window,suggesting a lifelong role in cortical plasticity under normal physiological conditions,and possibly under pathological conditions as well.This review discusses recent evidence regarding the detailed features of these unique cells,including their distribution,morphology,fate,temporal and spatial origin,as well as their relevance and possible functions in various physiological and pathological conditions.In addition,we review studies that have produced conflicting results,possibly as a result of discrepancies in the methodology used to detect neurogenesis.In theory,the properties of these cells indicate that they might exert a significant impact on neocortical function,informing potential therapeutic strategies designed to induce endogenous neurogenesis in the treatment of neuropathological diseases. | Mengqi Zhang Hui Wang Kun Xiong | 2011 | Neural Regeneration Research2011，6，17： | 2 |
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