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| 1 | Diet and epigenetics in colon cancer显示文摘Over the past few years, evidence has accumulated indicating that apart from genetic alterations, epigenetic alterations, through e.g. aberrant promoter methylation, play a major role in the initiation and progression of colorectal cancer (CRC). Even in the hereditary colon cancer syndromes, in which the susceptibility is inherited dominantly, cancer develops only as the result of the progressive accumulation of genetic and epigenetic alterations. Diet can both prevent and induce colon carcinogenesis, for instance, through epigenetic changes, which regulate the homeostasis of the intestinal mucosa. Food-derived compounds are constantly present in the intestine and may shift cellular balance toward harmful outcomes, such as increased susceptibility to mutations. There is strong evidence that a major component of cancer risk may involve epigenetic changes in normal cells that increase the probability of cancer after genetic mutation. The recognition of epigenetic changes as a driving force in colorectal neoplasia would open new areas of research in disease epidemiology, risk assessment, and treatment, especially in mutation carriers who already have an inherited predisposition to cancer. | Minna Nystrm Marja Mutanen | 2009 | World Journal of Gastroenterology2009，15，3： | 8 |
| 2 | A big step in the study of small cell lung cancer显示文摘 | Minna J D Kurie J M Jacks T | 2003 | Cancer Cell2003，4，： | 1 |
| 3 | Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lang and other cancers 显示文摘 | Zabarovsky E R Lerman M I Minna J D | 2002 | Oncogene2002，21，45： | 1 |
| 4 | Expression of bcl-2 in small cell lung carcinoma cells显示文摘 | Ikegaki N Katsumata M Minna JD | 1994 | Cancer Res1994，54，1： | 1 |
| 5 | Challenges in risk management in multi-company industrial parks显示文摘 | Anna-Mari H Yngve M Minna N | 2010 | Safety Science2010，48，4： | 1 |
| 6 | Vertebral endplate change as a feature of intervertebral disc degeneration: a heritability study显示文摘 | Juhani H. M??tt? Minna Kraatari Lisa Wolber Jaakko Niinim?ki Sam Wadge Jaro Karppinen Frances M. K. Williams | 2014 | European Spine Journal2014，，9： | 1 |
| 7 | In situ localization of collagen production by chondrocytes and osteoblasts in fracture callus显示文摘 | Minna S Hannu A Petler M | 1989 | J Bone Joint Surg1989，71，： | 1 |
| 8 | Links between plant community composition, soil organic matter quality and microbial communities in contrasting tundra habitats显示文摘 | Anu Eskelinen Sari Stark Minna M?nnist? | 2009 | Oecologia2009，，1： | 1 |
| 9 | Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma显示文摘 | Jarkko T. Korpi Jaana Hagstr?m Niko Lehtonen Jyrki Parkkinen Timo Sorsa Tuula Salo Minna Laitinen | 2010 | Surgical Oncology2010，，1： | 1 |
| 10 | Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers显示文摘 | Zabarovsky E R Lerman M I Minna J D | 2002 | Oncogene2002，21，45： | 1 |
| 11 | Links between plant community composition, soil organic matter quality and microbial communities in contrasting tundra habitats显示文摘 | Anu Eskelinen Sari Stark Minna Männistö | 2009 | Oecologia2009，，1： | 1 |
| 12 | Factors underlying attitude formation towards online banking in Finland显示文摘 | Heikki K Minna M Taplo P | 2002 | The International Journal of Bank Marketing2002，20，6： | 1 |
| 13 | Gene expression during bone repair 显示文摘 | Sanbderg M Hannu T | 1993 | Clin Orthop Res1993，289，2： | 1 |
| 14 | Synthetic lethal screen identification of chemosensitizer loci in cancer ceils显示文摘 | Bodemann BO Cardenas J Ferguson D Girard L Peyton M Minna JD Michnoff C Hao W Roth MG Xie XJ White MA | 2007 | Nature2007，446，： | 1 |
| 15 | CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity显示文摘 | Carboni GL Gao B Nishizaki M Xu K Minna JD Roth JA | | 0，，： | 1 |
| 16 | Molecular pathogenesis of lung cancer and potential translational applications显示文摘 | Minna J D Fong K Zochbauer M S | 2008 | Cancer J2008，8，1： | 1 |
| 17 | Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease显示文摘 | Giuseppa Mudò Johanna M?kel? Valentina Di Liberto Timofey V. Tselykh Melania Olivieri Petteri Piepponen Ove Eriksson Annika M?lki? Alessandra Bonomo Minna Kairisalo Jose A. Aguirre Laura Korhonen Natale Belluardo Dan Lindholm | 2012 | Cellular and Molecular Life Sciences2012，，7： | 1 |
| 18 | Efficacy of a novel PCR-and microarray-based method in diagnosis of a prosthetic joint infection显示文摘 | Metso L Minna M Tissari P | 2014 | Acta Orthop2014，85，2： | 1 |
| 19 | Molecular heterogeneity has a major impact on the measurement of circulating N-terminal fragments of A- and B-Type Natriuretic Peptides 显示文摘 | Jarkko M Keijo P | 2004 | Clin Chem2004，50，9： | 1 |
| 20 | Links between plant community composition, soil organic matter quality and microbial communities in contrasting tundra habitats显示文摘 | Anu Eskelinen Sari Stark Minna M?nnist? | 2009 | Oecologia2009，，1： | 1 |
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