|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Enhanced recovery program is safe and improves postoperative insulin resistance in gastrectomy显示文摘AIM: To assess the safety of enhanced recovery after surgery(ERAS) program in gastrectomy and influences on nutrition state and insulin-resistance. METHODS: Our ERAS program involved shortening the fasting periods and preoperative carbohydrate loading. Eighty gastrectomy patients were randomly assigned to either the conventional group(CG) or ERAS group(EG). We assessed the clinical characteristics and postoperative outcomes prospectively. The primary endpoint was noninferiority in timely discharge from the hospital within 12 d. Secondary endpoints were the incidence of aspiration at anesthesia induction, incidence of postoperative complications, health related quality of life(HRQOL) using the SF8 Health Survey questionnaire, nutrition state [e.g., albumin, transthyretin(TTR), retinal-binding protein(RBP), and transferrin(Tf)], the homeostasis model assessment-insulin resistance(HOMA-R) index, postoperative urine volume,postoperative weight change, and postoperative oral intake.RESULTS: The ERAS program was noninferior to the conventional program in achieving discharge from the hospital within 12 d(95.0% vs 92.5% respectively; 95%CI:-10.0%-16.0%). There was no significant difference in postoperative morbidity between the two groups. Adverse events such as vomiting and aspiration associated with the induction of general anesthesia were not observed. There were no significant differences with respect to postoperative urine volume, weight change, and oral intake between the two groups. EG patients with preoperative HOMA-R scores above 2.5 experienced significant attenuation of their HOMA-R scores on postoperative day 1 compared to CG patients(P = 0.014). There were no significant differences with respect to rapid turnover proteins(TTR, RBP and Tf) or HRQOL scores using the SF8 method.CONCLUSION: Applying the ERAS program to patients who undergo gastrectomy is safe, and improves insulin resistance with no deterioration in QOL. | Nobuaki Fujikuni Kazuaki Tanabe Noriaki Tokumoto Takahisa Suzuki Minoru Hattori Toshihiro Misumi Hideki Ohdan | 2016 | World Journal of Gastrointestinal Surgery2016，8，5： | 23 |
| 2 | Effect of NaCI and Helicobacter pylori vacuolating cytotoxin on cytokine expression and viability显示文摘瞄准:决定是否 Helicobacter pylori (H pylori ) vacuolating 细胞毒素(VacA ) 调整支持 inflammatory cytokines (IL-1beta, IL-8, TNF-alpha,和 IL-6 ) 的版本或改变胃的上皮的房间生存能力并且决定 NaCl 是否影响这些导致 VacA 的变化。方法:Vacuolating 活动被测量中性红的举起进对待 VacA 的人的液泡决定胃上皮(AGS ) 房间。AGS 房间生存能力被直接房间数估计。特定的连接酶的免疫吸着剂试金(ELISA ) 和反向的 transcriptase 聚合酶链反应(RT-PCR ) 被执行在 AGS 房间在房间支持 inflammatory cytokine 生产上检验 H pylori VacA 和 NaCl 的效果。从蒙古的沙鼠胃的织物染色的 Immunohistochemical 被用来在这导致 VacA 的回答上证实导致 VacA 的支持 inflammatory cytokine 生产和 NaCl 的效果。结果:VacA 的增加独自减少了 AGS 房间生存能力(P <
0.05 ) ,并且这减小被 NaCl 的高剂量提高(P <
0.05 ) 。VacA 独自导致了 TNF-alpha, IL-8 和 IL-1beta 的表示,当 NaCl 独自导致了 TNF-alpha 和 IL-1beta 的表示时。在 mRNA 层次的变化面对 VacA 和 NaCl 是更复杂的。为 TNF-alpha 的盒子,表示是 NaCl 上的剂量依赖者。IL-6 mRNA 没被检测。然而, IL-6 的底层被 ELISA 检测。IL-1, IL-6,和 TNF-alpha 的组织化学的染色在 H 感染 pylori 的沙鼠的胃的织物被发现的积极免疫用一本正常食谱或高盐喂了饮食。然而,染色这三 cytokines 在用 5 g/kg NaCl 食谱喂的 H 感染 pylori 的动物是更强壮的。结论:VacA 减少 AGS 房间的生存能力,和这效果能被 NaCl 提高。NaCl 也影响 VacA 导致的支持 inflammatory cytokines 的生产,建议 NaCl 起在 H 导致 pylori 的胃的上皮的房间细胞毒性的一个重要作用。 | Juan Sun Kazuo Aoki Jin-Xu Zheng Bing-Zhong Su Xiao-Hui Ouyang Junichi Misumi | 2006 | World Journal of Gastroenterology2006，12，14： | 2 |
| 3 | Successful production of piglets derived from vitrified morulae and early blastocysts using a microdroplet method显示文摘 | Kouji Misumi Misae Suzuki Shuji Sato Norio Saito | 2003 | Theriogenology2003，60，： | 1 |
| 4 | Electrocardiographic discrimination of infarct-related artery between left circumflex and right coronary artery:comparison of ST elevation between leads Ⅱ and Ⅲ显示文摘 | Misumi I School H Nakao K | 2003 | Cardiol2003，41，6： | 1 |
| 5 | Tei index evaluated by M-mode echocardiography in patients with dilated cardiomyopathy 显示文摘 | Tei Misumi I Harada E Doi H | 2002 | J Cardiol2002，39，2： | 1 |
| 6 | Tei index evaluated by M-mode echocardiography in patients with dilated cardiomyopathy显示文摘 | Tei Misumi I Harada E Doi H | 2002 | J Cardiol2002，39，2： | 1 |
| 7 | The interaction of two tethering factors, p115 and COG complex, is required for Golgi integrity 显示文摘 | Sohda M Misumi Y Yashimura S | 2007 | Traffic2007，8，3： | 1 |
| 8 | Cytokine production profile in patients with Behcet's disease treated with infiiximab显示文摘 | Misumi M Hagiwara E Takeno M | 2003 | Cytokine2003，24，： | 1 |
| 9 | The role of tumor necrosis factor-α in the aggravation of cerulein-induced pancreatitis in rats显示文摘 | Hirofumi Sameshima Satoshi Ikei Katsutaka Mori Yasuo Yamaguchi Hiroshi Egami Mikio Misumi Masaya Moriyasu Michio Ogawa | 1993 | International Journal of Pancreatology1993，，2： | 1 |
| 10 | Depletion of vesicle-tethering factor p115 causes mini-stacked Golgi fragments with delayed pro- tein transport显示文摘 | Sohda M Misumi Y Yoshimura S | 2005 | Biochem Biophys Res Commun2005，338，2： | 1 |
| 11 | A cyclic dodecapeptide-multiple-antigen peptide conjugate from the undecapeptidyl arch (from Arg(168) to Cys(178)) of extracellular loop 2 in CCR5 as a novel human immunodeficiency virus type 1 vaccine显示文摘 | Misumi S Nakajirna R Takamune N | 2001 | J Virol2001，75，11： | 1 |
| 12 | Electrocardiographic discrimination of infarct-related artery between left circumflex and right coronary artery: comparison of ST elevation between laeds Ⅱ and Ⅲ 显示文摘 | Shono H Nakao K | 2003 | J Cardiol2003，41，6： | 1 |
| 13 | A novel cyclic peptide immunization strategy for preventing HIV1/ AIDS infection and progression 显示文摘 | Misumi S Endo M Mukai R | 2003 | J Biol Chem2003，278，32： | 1 |
| 14 | In vitro thymidine kinase/ganciclovir-based suicide gene therapy using replication defective herpes simplex virus- 1 against leukemic B- cell malignancies (MCL, HCL, B-CLL) 显示文摘 | Misumi M Suzuki T Moriuchi S | 2003 | Leuk Res2003，27，8： | 1 |
| 15 | Studies on alkaline phosphatase isoenzymes in gastric garcinoma tissue 显示文摘 | Takagi K Meano M Misumi A | 1981 | Gastroenterol Jap1981，6，： | 1 |
| 16 | Statistical analysis of serum pepsinogen Ⅰ (PG Ⅰ) and Ⅱ (PGⅡ)levels,PGⅠ /PGⅡ ratios and serum gas trin levels in a general population显示文摘 | Aoki K Misumi J | 1996 | Environ Health and Prev Med1996，1，： | 1 |
| 17 | Reduction of various ketones by red algae显示文摘 | Utsukihara T Misumi O Kato N | 2006 | Tetrahedron:Asymmetry2006，17，8： | 1 |
| 18 | Influenceof Gas Mixture Fumigation of Ethyl Formate and CarbonDioxide on Several Characteristics of Fresh Fruitsand Vegetables (Bananas, Pineapples, Strawberries,Grapefruits, Satsuma mandarins, Squashes, and OtherVegetables)显示文摘 | MISUMI T YAMADA K OGAWA N | 2013 | 植物防疫所调查报告2013，49，： | 1 |
| 19 | Diastereoselective asymmetric nitro-aldol reaction of α-amino aldehydes under high pressure without catalyst 显示文摘 | Misumi Y Matsumoto K | 2002 | Angew Chem Int Ed2002，41，6： | 1 |
| 20 | Nordihydroguaiaretic acid blocks protein transport in the secretory pathway causing redistribution of Golgi proteins into the endoplasmic reticulum显示文摘 | Fujiwara T Takami N Misumi Y | 1998 | J Biol Chem1998，273，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员