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| 1 | Effect of NaCI and Helicobacter pylori vacuolating cytotoxin on cytokine expression and viability显示文摘瞄准:决定是否 Helicobacter pylori (H pylori ) vacuolating 细胞毒素(VacA ) 调整支持 inflammatory cytokines (IL-1beta, IL-8, TNF-alpha,和 IL-6 ) 的版本或改变胃的上皮的房间生存能力并且决定 NaCl 是否影响这些导致 VacA 的变化。方法:Vacuolating 活动被测量中性红的举起进对待 VacA 的人的液泡决定胃上皮(AGS ) 房间。AGS 房间生存能力被直接房间数估计。特定的连接酶的免疫吸着剂试金(ELISA ) 和反向的 transcriptase 聚合酶链反应(RT-PCR ) 被执行在 AGS 房间在房间支持 inflammatory cytokine 生产上检验 H pylori VacA 和 NaCl 的效果。从蒙古的沙鼠胃的织物染色的 Immunohistochemical 被用来在这导致 VacA 的回答上证实导致 VacA 的支持 inflammatory cytokine 生产和 NaCl 的效果。结果:VacA 的增加独自减少了 AGS 房间生存能力(P <
0.05 ) ,并且这减小被 NaCl 的高剂量提高(P <
0.05 ) 。VacA 独自导致了 TNF-alpha, IL-8 和 IL-1beta 的表示,当 NaCl 独自导致了 TNF-alpha 和 IL-1beta 的表示时。在 mRNA 层次的变化面对 VacA 和 NaCl 是更复杂的。为 TNF-alpha 的盒子,表示是 NaCl 上的剂量依赖者。IL-6 mRNA 没被检测。然而, IL-6 的底层被 ELISA 检测。IL-1, IL-6,和 TNF-alpha 的组织化学的染色在 H 感染 pylori 的沙鼠的胃的织物被发现的积极免疫用一本正常食谱或高盐喂了饮食。然而,染色这三 cytokines 在用 5 g/kg NaCl 食谱喂的 H 感染 pylori 的动物是更强壮的。结论:VacA 减少 AGS 房间的生存能力,和这效果能被 NaCl 提高。NaCl 也影响 VacA 导致的支持 inflammatory cytokines 的生产,建议 NaCl 起在 H 导致 pylori 的胃的上皮的房间细胞毒性的一个重要作用。 | Juan Sun Kazuo Aoki Jin-Xu Zheng Bing-Zhong Su Xiao-Hui Ouyang Junichi Misumi | 2006 | World Journal of Gastroenterology2006，12，14： | 2 |
| 2 | Intracystic hemorrhage of a simple liver cyst mimicking a biliary cystadenocarcinoma显示文摘 | Yasuhiro Kitajima Yasutaka Okayama Masaaki Hirai Kazuki Hayashi Hideto Imai Tetsu Okamoto Shigeru Aoki Shinji Akita Kazuo Gotoh Hirotaka Ohara Tomoyuki Nomura Takashi Joh Yoshifumi Yokoyama Makoto Itoh | 2003 | Journal of Gastroenterology2003，，2： | 1 |
| 3 | Fundamental study of re- flection pulse oximetry显示文摘 | Keisuke Matsushita Kazuo Aoki | 2003 | Optical Review2003，10，5： | 1 |
| 4 | Load Sensing Fluid Power System显示文摘 | Yasuo Aoki Kazuo Ue hara Ka zu yu ki Hirose | | SAE paper0，，： | 1 |
| 5 | Load Sensing Fluid Power System显示文摘 | Yasuo Aoki Kazuo Ue hara Ka zu yu ki Hirose | | SAE paper0，，： | 1 |
| 6 | Conophylline suppresses hepatic stellate cells and attenuates thioacetamide‐induced liver fibrosis in rats显示文摘 | Norio Kubo Rie Saito Kunihisa Hamano Masahiro Nagasawa Fumiaki Aoki Izumi Takei Kazuo Umezawa Hiroyuki Kuwano Itaru Kojima | 2014 | Liver Int2014，，7： | 1 |
| 7 | Age related characteristics of uterine cancer mortality in Japan显示文摘 | Kazuo Aoki Juan Sun Akihiro Kono | 2005 | Arch Gynecol Obstet2005，273，： | 1 |
| 8 | Splat profile of impinging droplets on rough substrates:influence of surface roughness 显示文摘 | Shigeyasu Amada Kazuo Imagawa Satoshi Aoki | 2002 | Surface and Coatings Technology2002，154，： | 1 |
| 9 | A nonclassical vitamin D receptor pathway suppresses renal fibrosis显示文摘 | Ito Ichiaki Waku Tsuyoshi Aoki Masato Abe Rumi Nagai Yu Watanabe Tatsuya Nakajima Yuka Ohkido Ichiro Yokoyama Keitaro Miyachi Hiroyuki Shimizu Toshiyuki Murayama Akiko Kishimoto Hiroyuki Nagasawa Kazuo Yanagisawa Junn | 2013 | Journal of Clinical Investigation2013，，11： | 1 |
| 10 | Fundamental Study of Reflection Pulse Oximetry显示文摘 | Keisuke Matsushita Kazuo Aoki Naoto Kakuta | | 0，，： | 1 |
| 11 | Intracystic hemorrhage of a simple liver cyst mimicking a biliary cystadenocarcinoma显示文摘 | Yasuhiro Kitajima Yasutaka Okayama Masaaki Hirai Kazuki Hayashi Hideto Imai Tetsu Okamoto Shigeru Aoki Shinji Akita Kazuo Gotoh Hirotaka Ohara Tomoyuki Nomura Takashi Joh Yoshifumi Yokoyama Makoto Itoh | 2003 | Journal of Gastroenterology2003，，2： | 1 |
| 12 | Load Sensing Fluid Power System显示文摘 | Yasuo Aoki Kazuo Ue hara Ka zu yu ki Hirose | | SAE paper0，，： | 1 |
| 13 | Load Sensing Fluid Power System显示文摘 | Yasuo Aoki Kazuo Uehara Kazuyuki Hirose | | SAE paper0，，： | 1 |
| 14 | Ten year's progress of Syowa Station, Antarctica, as a global geodesy network site显示文摘 | Kazuo Shibuya Koichiro Doi and Shigeru Aoki | 2003 | Polar Geosci2003，16，： | 1 |
| 15 | Lnsd Sensing Fluid Power Systems显示文摘 | Yasuo Aoki Kazuo Uehara | 1994 | SAE(Society of Automotive Engineers)Transactions1994，2，： | 1 |
| 16 | Expression and role of GLUT-1, MCT-1, and MCT-4 in malignant pleural mesothelioma显示文摘 | Ai Mogi Kaori Koga Mikiko Aoki Makoto Hamasaki Noriko Uesugi Akinori Iwasaki Takayuki Shirakusa Kazuo Tamura Kazuki Nabeshima | 2013 | Virchows Archiv2013，，1： | 1 |
| 17 | Numerical Simulations of Rarefied Gases in Curved Channels: Thermal Creep, Circulating Flow, and Pumping Effect显示文摘We present numerical simulations of a new system of micro-pump based on the thermal creep effect described by the kinetic theory of gases.This device is made of a simple smooth and curved channel with a periodic temperature distribution.Using the Boltzmann-BGK model as the governing equation for the gas flow,we develop a numerical method based on a deterministic finite volume scheme,implicit in time,with an implicit treatment of the boundary conditions.This method is comparatively less sensitive to the slow flow velocity than the usual Direct Simulation Monte Carlo method in case of long devices,and turns out to be accurate enough to compute macroscopic quantities like the pressure field in the channel.Our simulations show the ability of the device to produce a one-way flow that has a pumping effect. | Kazuo Aoki Pierre Degond Luc Mieussens | 2009 | Communications in Computational Physics2009，6，10： | 1 |
| 18 | Increased Connective Tissue Growth Factor Relative to Brain Natriuretic Peptide as a Determinant of Myocardial Fibrosis显示文摘 | Norimichi Koitabashi Masashi Arai Shinya Kogure Kazuo Niwano Atai Watanabe Yasuhiro Aoki Toshitaka Maeno Takashi Nishida Satoshi Kubota Masaharu Takigawa Masahiko Kurabayashi | 2007 | Hypertension2007，，5： | 1 |
| 19 | Effects of Cow’s Milk on Reproduction in ICR Male Mice显示文摘Objective To study the effects of Cow’s milk on the reproduction in male mice. Methods Twenty-four male mice were divided randomly into two groups: milk group (M) and control group (C). Each mouse was given 10 mL milk per day from 4 to 16 weeks in the group M. At the age of 17 weeks, all the mice were sacrificed. Results Serum testosterone was decreased in the group M (P=0.037). No significant difference was found in weight of testes, seminal vesicle or adrenal gland of mice between the groups C and M. However, the weight of seminal vesicle decreased when expressed in g/100 g body weight in the group M. Epididymal sperm concentration, motility, morphology, and sperm head number were not affected by milk. Conclusion Cow’s milk has adverse effects on the reproductive system in ICR male mice. Further studies are needed to clarify the specific effects of milk on reproductive health. | YU-XIA MA NAOYUKI EBINE KAZUO AOKI MASAHIRO KUSUNOKI AND JUNICHI MISUMI | 2009 | Biomedical and Environmental Sciences2009，22，2： | 0 |
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