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| 1 | Emergency department procedural sedation for primary electrical cardioversion — a comparison with procedural sedations for other reasons显示文摘BACKGROUND: Atrial fibrillation(AF) is the most common arrhythmia treated in the emergency department(ED), with primary electrical cardioversion(PEC) the preferred method of rhythm control. Anecdotally, patients undergoing ED procedural sedation(EDPS) for PEC differ from those requiring EDPS for other procedures: they are at higher risk of adverse events, and require fewer drugs and lower doses. We attempt to verify this using an EDPS registry at a Canadian, tertiary care teaching hospital.METHODS: This is a retrospective review of patients that underwent EDPS for the period of June 2006 to September 2014. We compared demographics, medication use and intra-procedural adverse events between those receiving EDPS for PEC for AF compared to that for other indications. We report the asssociation between AEs and predictors using logistic regression.RESULTS: A total of 4 867 patients were included, 714 for PEC for AF and 4 153 for other indications. PEC patients were more likely male(58.5% vs. 47.1%), older(59.5 years vs. 48.1 years), and less likely to be ASA I(46.6% vs. 69.0%). PEC patients received smaller doses of propofol and less likely to receive adjuvant analgesic therapy(11.5% vs. 78.2%). PEC patients were more likely to experience hypotension(27.6% vs. 16.5%) but respiratory AEs(apnea, hypoxia and airway intervention) were not different.CONCLUSION: EDPS for PEC differs from that conducted for other purposes: patients tend to be less healthy, receive smaller doses of medication and more likely to suffer hypotension without an increase in respiratory AEs. These factors should be considered when performing EDPS. | Michael Butler Patrick Froese Peter Zed George Kovacs Robert Mac Kinley Kirk Magee Mary-Lynn Watson Samuel G.Campbell | 2017 | World Journal of Emergency Medicine2017，8，3： | 6 |
| 2 | Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease:A definitive diagnostic test?显示文摘AIM: To investigate the utility of scintigraphic studies in predicting response to laparoscopic fundoplication(LF) for chronic laryngopharyngeal reflux symptoms.METHODS: Patients with upper aero-digestive symptoms that remained undiagnosed after a period of 2 mo were studied with conventional p H and manometric studies. Patients mainly complained of cough, sore throat, dysphonia and globus. These patients were imaged after ingestion of 99m-technetium diethylene triamine pentaacetic acid. Studies were quantified with time activity curves over the pharynx, upper and lower oesophagus and background. Late studies of the lungs were obtained for aspiration. Patients underwent LF with post-operative review at 3 mo after surgery.RESULTS: Thirty four patients(20 F, 14 M) with an average age of 57 years and average duration of symptoms of 4.8 years were studied. Twenty four hour p H and manometry studies were abnormal in all patients. On scintigraphy, 27/34 patients demonstrated pharyngeal contamination and a rising or flat pharyngeal curve. Lung aspiration was evident in 50% of patients. There was evidence of pulmonary aspiration in 17 of 34 patients in the delayed study(50%). Pharyngeal contamination was found in 27 patients. All patients with aspiration showed pharyngeal contamination. In the 17 patients with aspiration, graphical time activity curve showed rising activity in the pharynx in 9 patients and a flat curve in 8 patients. In those 17 patients without pulmonary aspiration, 29%(5 patients) had either a rising or flat pharyngeal graph. A rising or flat curve predicted aspiration with a positive predictive value of 77% and a negative predictive valueof 100%. Over 90% of patients reported a satisfactory symptomatic response to LF with an acceptable sideeffect profile. CONCLUSION: Scintigraphic reflux studies offer a good screening tool for pharyngeal contamination and aspiration in patients with gastroesophageal reflux disease. | Gregory L Falk John Beattie Alvin Ing SE Falk Michael Magee Leticia Burton Hans Van der Wall | 2015 | World Journal of Gastroenterology2015，21，12： | 2 |
| 3 | The changing Social implications of vesicovaginal fistulas:Linking vesical cat heters-A useful adjunct显示文摘 | Magee | 1979 | Journal of1979，，： | 1 |
| 4 | Dechlorination of PCB in the presence of plant nitrate reductase显示文摘 | MAGEE K D MICHAEL A ULLAH H | 2008 | Enviro Toxicol Pharmacol2008，25，： | 1 |
| 5 | Softwaretransactional memory:why is it only a research toy 显示文摘 | Calin Cascava Blundell Colin Maged Michael | 2008 | CACM2008，51，11： | 1 |
| 6 | Dechlorination of PCB in the presence of plant nitrate reductase显示文摘 | Magee D K Michael A Ullah H | 2008 | Environmental Toxicology and Pharmacology2008，25，2： | 1 |
| 7 | A uroguanylin-GUCY2C endocrine axis regulates feeding in mice显示文摘 | Valentino Michael A Lin Jieru E Snook Adam E Li Peng Kim Gilbert W Marszalowicz Glen Magee Michael S Hyslop Terry Schulz Stephanie Waldman Scott A | 2011 | Journal of Clinical Investigation2011，，9： | 1 |
| 8 | Combined Percutaneous And Retrograde Approach To Staghorn Calculi With Application Of The Ureteral Access Sheath To Facilitate Percutaneous Nephrolithotomy显示文摘 | JAIME LANDMAN RAMAKRISHNA VENKATESH DAVID I. LEE JAMIL REHMAN MAGED RAGAB MICHAEL DARCY CHANDRU P. SUNDARAM | 2003 | The Journal of Urology2003，，1： | 1 |
| 9 | Is routine measurement of international normalized ratio necessary as part of the investigation of patients with cardiac-type chest pain?显示文摘Dear editor, Chest pain is a frequent complaint of patients presenting to the emergency department (ED), and many of them are referred to the cardiology service for further investigation. At the Charles V. Keating Emergency and Trauma Centre in Halifax, Nova Scotia, Canada, 4,800 (6.6%) of the approximately 73,000 patients per year register with a complaint of “chest pain”, and 20% of patients are referred to cardiology. Coagulation studies, specifi cally international normalized ratio (INR) frequently part of the “routine” panel of blood tests, are ordered for patients in the ED being investigated or treated for chest pain suspected to be cardiac in nature. Recent calls to examine how much of our practice is likely to benefit patients in any way have led us to question the clinical utility of routine use of these tests. | Samuel G.Campbell Kirk Magee Ismail Cajee Simon Field Michael B.Butler Christine L.Campbell Sarah E.Bryson | 2021 | World Journal of Emergency Medicine2021，12，3： | 1 |
| 10 | Stefanie chiras and siddhartha chatterjee software transactional memory: why is it only a research toy显示文摘 | Calin Caseaval Colin Blundell Maged Michael | 2008 | Queue2008，6，5： | 1 |
| 11 | A randomized, controlled trial of the role of weaning predictors in clinical decision making显示文摘 | Maged A Michael L Katherine P | 2006 | Cri Car Med2006，34，10： | 1 |
| 12 | A randomized,cnntrolled trial of the role of weaning predictors in clinical decision making 显示文摘 | Maged A Michael L Katherine P | 2006 | Cri Car Med2006，34，10： | 1 |
| 13 | Primary Results of the HABIT Trial (Heart Failure Assessment With BNP in the Home)显示文摘 | Alan Maisel Denise Barnard Brian Jaski Geir Frivold John Marais Maged Azer Michael I. Miyamoto Dawn Lombardo Damon Kelsay Kelly Borden Navaid Iqbal Pam R. Taub Ken Kupfer Paul Clopton Barry Greenberg | 2013 | Journal of the American College of Cardiology2013，，16： | 1 |
| 14 | GUCY2C-targeted cancer immunotherapy: past, present and future显示文摘 | Adam E. Snook Michael S. Magee Scott A. Waldman | 2011 | Immunologic Research2011，，2： | 1 |
| 15 | Long-term characterization of retinal degeneration in rd1 and rd10 mice using spectral domain optical coherence tomography显示文摘 | Pennesi ME Michaels KV Magee SS | 2012 | Invest Ophthalmol Vis Sci2012，53，： | 1 |
| 16 | End-tidal capnometry during emergency department procedural sedation and analgesia: a randomized, controlled study显示文摘BACKGROUND:This prospective,randomized trial was undertaken to evaluate the utility of adding end-tidal capnometry(ETC)to pulse oximetry(PO)in patients undergoing procedural sedation and analgesia(PSA)in the emergency department(ED).METHODS:The patients were randomized to monitoring with or without ETC in addition to the current standard of care.Primary endpoints included respiratory adverse events,with secondary endpoints of level of sedation,hypotension,other PSA-related adverse events and patient satisfaction.RESULTS:Of 986 patients,501 were randomized to usual care and 485 to additional ETC monitoring.In this series,48%of the patients were female,with a mean age of 46 years.Orthopedic manipulations(71%),cardioversion(12%)and abscess incision and drainage(12%)were the most common procedures,and propofol and fentanyl were the sedative/analgesic combination used for most patients.There was no difference in patients experiencing de-saturation(Sa O2<90%)between the two groups;however,patients in the ETC group were more likely to require airway repositioning(12.9%vs.9.3%,P=0.003).Hypotension(SBP<100 mm Hg or<85 mm Hg if baseline<100 mm Hg)was observed in 16(3.3%)patients in the ETC group and 7(1.4%)in the control group(P=0.048).CONCLUSIONS:The addition of ETC does not appear to change any clinically significant outcomes.We found an increased incidence of the use of airway repositioning maneuvers and hypotension in cases where ETC was used.We do not believe that ETC should be recommended as a standard of care for the monitoring of patients undergoing PSA. | Samuel G. Campbell Kirk D. Magee Peter J. Zed Patrick Froese Glenn Etsell Alan LaPierre Donna Warren Robert R. MacKinley Michael B. Butler George Kovacs David A. Petrie | 2016 | World Journal of Emergency Medicine2016，7，1： | 0 |
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