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| 1 | Update on occult hepatitis B virus infection显示文摘The event of mutations in the surface antigen gene of hepatitis B virus(HBV) results in undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core(anti-HBc) antibody status in serum and this phenomenon is named occult hepatitis B infection(OBI). The presence of anti-HBc antibody in serum is an important key for OBI tracking, although about 20% of OBI cases are negative for anti-HBc antibody. The diagnosis of OBI is mainly based on polymerase chain reaction(PCR) and real-time PCR assays. However, real-time PCR is a more reliable method than PCR. OBI is a great issue for the public health problem and a challenge for the clinical entity worldwide. The persistence of OBI may lead to the development of cirrhosis and hepatocellular carcinoma. With regard to OBI complications, the screening of HBV DNA by the highly sensitive molecular means should be implemented for:(1) patients with a previous history of chronic or acute HBV infection;(2) patients co-infected with hepatitis C virus/human immunodeficiency virus;(3) patients undergoing chemotherapy or anti-CD20 therapy;(4) recipients of organ transplant;(5) blood donors;(6) organ transplant donors;(7) thalassemia and hemophilia patients;(8) health care workers;(9) patients with liver related disease(cryptogenic);(10) hemodialysis patients;(11) patients undergoing lamivudine or interferon therapy; and(12) children in time of HBV vaccination especially in highly endemic areas of HBV. Active HBV vaccination should be implemented for the close relatives of patients who are negative for OBI markers. Thus, the goal of this review is to evaluate the rate of OBI with a focus on status of high risk groups in different regions of the world. | Manoochehr Makvandi | 2016 | World Journal of Gastroenterology2016，22，39： | 28 |
| 2 | Engineering Microneedle Patches for Improved Penetration:Analysis,Skin Models and Factors Affecting Needle Insertion显示文摘Transdermal microneedle(MN)patches are a promising tool used to transport a wide variety of active compounds into the skin.To serve as a substitute for common hypodermic needles,MNs must pierce the human stratum corneum(~10 to 20μm),without rupturing or bending during penetration.This ensures that the cargo is released at the predetermined place and time.Therefore,the ability of MN patches to sufficiently pierce the skin is a crucial requirement.In the current review,the pain signal and its management during application of MNs and typical hypodermic needles are presented and compared.This is followed by a discussion on mechanical analysis and skin models used for insertion tests before application to clinical practice.Factors that affect insertion(e.g.,geometry,material composition and cross-linking of MNs),along with recent advancements in developed strategies(e.g.,insertion responsive patches and 3D printed biomimetic MNs using two-photon lithography)to improve the skin penetration are highlighted to provide a backdrop for future research. | Pooyan Makvandi Melissa Kirkby Aaron RJHutton Majid Shabani Cynthia K.Y.Yiu Zahra Baghbantaraghdari Rezvan Jamaledin Marco Carlotti Barbara Mazzolai Virgilio Mattoli Ryan F.Donnelly | 2021 | Nano-Micro Letters2021，13，6： | 5 |
| 3 | Prevascularized Micro‑/Nano‑Sized Spheroid/Bead Aggregates for Vascular Tissue Engineering显示文摘Efficient strategies to promote microvascularization in vascular tissue engineering,a central priority in regenerative medicine,are still scarce;nano-and micro-sized aggregates and spheres or beads harboring primitive microvascular beds are promising methods in vascular tissue engineering.Capillaries are the smallest type and in numerous blood vessels,which are distributed densely in cardiovascular system.To mimic this microvascular network,specific cell components and proangiogenic factors are required.Herein,advanced biofabrication methods in microvascular engineering,including extrusion-based and droplet-based bioprinting,Kenzan,and biogripper approaches,are deliberated with emphasis on the newest works in prevascular nano-and micro-sized aggregates and microspheres/microbeads. | Maedeh Rahimnejad Narges Nasrollahi Boroujeni Sepideh Jahangiri Navid Rabiee Mohammad Rabiee Pooyan Makvandi Omid Akhavan Rajender S.Varma | 2021 | Nano-Micro Letters2021，13，11： | 2 |
| 4 | A novel and more sensitive loop-mediated isothermal amplification assay targeting IS6110 for detection of Mycobacterium tuberculosis complex显示文摘 | Aryan E Makvandi M Farajzadeh A | 2010 | Microbiol Res2010，165，3： | 1 |
| 5 | A novel and moresensitive loop-mediated isothermal amplification assaytargeting IS6110 for detection of Mycobacterium tuberculosiscomplex显示文摘 | Aryan E Makvandi M Farajzadeh A | 2010 | Microbiol Res2010，165，3： | 1 |
| 6 | Failure Analysis of a Drilling Wire Rope 显示文摘 | Moradi S Ranjbar K Makvandi H | 2012 | Journal of Failure Analysis and Prevention2012，12，5： | 1 |
| 7 | Determination of rotavirus, sapo virus and norovirus coinfection among children suffering from gastroenteritis显示文摘 | Parsa-Nahad M Samarbaf-Zadeh A Makvandi M | 2011 | IranJ Virol2011，5，4： | 1 |
| 8 | Management and outcomeof a varicella exposure in a neonatal intensive care unit : lessonsfor the vaccine era 显示文摘 | Kellie SM Makvandi M Muller ML | 2011 | Am J Infect Control2011，39，10： | 1 |
| 9 | The highest prevalence of human metapneumovirus in Ahwaz children accompanied by acute respiratory infections显示文摘 | Arabpour M Samarbafzadeh AR Makvandi M | 2008 | Indian J Med Microbiol2008，26，2： | 1 |
| 10 | Effect of birth ball on labor pain relief: A systematic review and meta-analysis显示文摘 | Makvandi S Latifnejad Roudsari R Sadeghi R | 2015 | J Obstet Gynaecol Res2015，41，11： | 1 |
| 11 | Engineered high-strength biohydrogel as a multifunctional platform to deliver nucleic acid for ameliorating intervertebral disc degeneration显示文摘Intervertebral disc degeneration(IVDD)is a leading cause of low back pain.The strategy of using functional materials to deliver nucleic acids provides a powerful tool for ameliorating IVDD.However,the immunogenicity of nucleic acid vectors and the poor mechanical properties of functional materials greatly limit their effects.Herein,antagomir-204-3p(AM)shows low immunogenicity and effectively inhibits the apoptosis of nucleus pulposus cells.Moreover,a high-strength biohydrogel based on zinc-oxidized sodium alginate-gelatin(ZOG)is designed as a multifunctional nucleic acid delivery platform.ZOG loaded with AM(ZOGA)exhibits great hygroscopicity,antibacterial activity,biocompatibility,and biodegradability.Moreover,ZOGA can be cross-linked with nucleus pulposus tissue to form a high-strength collagen network that improves the mechanical properties of the intervertebral disc(IVD).In addition,ZOGA provides an advantageous microenvironment for genetic expression in which AM can play an efficient role in maintaining the metabolic balance of the extracellular matrix.The results of the radiological and histological analyses demonstrate that ZOGA restores the height of the IVD,retains moisture in the IVD,and maintains the tissue structure.The ZOGA platform shows the sustained release of nucleic acids and has the potential for application to ameliorate IVDD,opening a path for future studies related to IVD. | Tao Chen Qiuping Qian Pooyan Makvandi Ehsan Nazarzadeh Zare Qizhu Chen Linjie Chen Zhiguang Zhang Hao Zhou Wenxian Zhou Hui Wang Xiangyang Wang Yu Chen Yunlong Zhou Aimin Wu | 2023 | Bioactive Materials2023，，7： | 1 |
| 12 | A novel and more sensitive loop-mediated isothermal amplification assay targeting 1S6110 for detection of Mycobacterium tuberculosis complex显示文摘 | ARYAN E MAKVANDI M FARAJZADEH A | 2009 | Microbiol Res2009，5，1： | 1 |
| 13 | Cytokine Profiles and Cell Proliferation Responses to Truncated ORF2 Protein in Iranian Patients Recovered from Hepatitis E Infection显示文摘 | Reza Taherkhani Fatemeh Farshadpour Manoochehr Makvandi Hamid Rajabi Memari Ali Reza Samarbafzadeh Nasrin Sharifi Behrouz Naeimi Saeed Tajbakhsh Samad Akbarzadeh Susana A. Laucella | 2015 | Journal of Tropical Medicine2015，，： | 1 |
| 14 | Design and production of a multiepitope construct derived from hepatitis E virus capsid protein显示文摘 | Reza Taherkhani Fatemeh Farshadpour Manoochehr Makvandi | 2015 | J. Med. Virol2015，，7： | 1 |
| 15 | Prevalence of Hepatitis E Virus among Adults in South-West of Iran显示文摘 | Fatemeh Farshadpour Reza Taherkhani Manoochehr Makvandi Piero Luigi Almasio | 2015 | Hepatitis Research and Treatment2015，，： | 1 |
| 16 | A novel and more sensitive loop-mediated isothermal amplification assay targeting IS6110 for detection of Mycobacterium tuberculosis complex 显示文摘 | Aryan E Makvandi M Farajzadeh A | 2010 | Microbiol Res2010，165，3： | 1 |
| 17 | A novel and more sensitive loop-mediated isothermal amplification assay targeting IS6110 for detection of mycobacterium tuberculosis complex显示文摘 | Aryan E Makvandi M Farajzadeh A | 2010 | Microbiol Res2010，165，3： | 1 |
| 18 | Occult Hepatitis B Virus Among the Patients With Abnormal Alanine Transaminase 显示文摘 | Makvandi M Neisi N Khalafkhany D | 2014 | Jundishapur J Microbiol2014，7，11： | 1 |
| 19 | Serotype determination of adenoviruses in children with respiratory infection显示文摘 | Ghasemi Y Makvandi M Samarbafzadeh AR | 2014 | Indian J Pediatr2014，81，7： | 1 |
| 20 | Failure Analysis of a Drilling Wire Rope 显示文摘 | S · Moradi K ·Ranjbar H · Makvandi | 2012 | Journal of Failure Analysis and Pre- vention2012，2527，： | 1 |
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