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| 1 | Update on occult hepatitis B virus infection显示文摘The event of mutations in the surface antigen gene of hepatitis B virus(HBV) results in undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core(anti-HBc) antibody status in serum and this phenomenon is named occult hepatitis B infection(OBI). The presence of anti-HBc antibody in serum is an important key for OBI tracking, although about 20% of OBI cases are negative for anti-HBc antibody. The diagnosis of OBI is mainly based on polymerase chain reaction(PCR) and real-time PCR assays. However, real-time PCR is a more reliable method than PCR. OBI is a great issue for the public health problem and a challenge for the clinical entity worldwide. The persistence of OBI may lead to the development of cirrhosis and hepatocellular carcinoma. With regard to OBI complications, the screening of HBV DNA by the highly sensitive molecular means should be implemented for:(1) patients with a previous history of chronic or acute HBV infection;(2) patients co-infected with hepatitis C virus/human immunodeficiency virus;(3) patients undergoing chemotherapy or anti-CD20 therapy;(4) recipients of organ transplant;(5) blood donors;(6) organ transplant donors;(7) thalassemia and hemophilia patients;(8) health care workers;(9) patients with liver related disease(cryptogenic);(10) hemodialysis patients;(11) patients undergoing lamivudine or interferon therapy; and(12) children in time of HBV vaccination especially in highly endemic areas of HBV. Active HBV vaccination should be implemented for the close relatives of patients who are negative for OBI markers. Thus, the goal of this review is to evaluate the rate of OBI with a focus on status of high risk groups in different regions of the world. | Manoochehr Makvandi | 2016 | World Journal of Gastroenterology2016，22，39： | 28 |
| 2 | Clinical features of hepatopulmonary syndrome in cirrhotic patients显示文摘瞄准:评估频率,临床并且帕拉肝肺症候群(HPS ) 并且到的临床的特征在伊朗在病人在这症候群的诊断决定他们的预兆的价值。方法:54 个肝脏硬化症的病人经历了对比由二位心脏病专家检测肺内、心内的分流的提高的回响心动描记法。动脉的血氧, O (2 ) 坡度(A-a ) 和正统说法被气体(ABG ) 测试的动脉的血测量。为 HPS 的诊断标准积极的病人被定义为表明肺内的动脉的膨胀的临床的 HPS 盒子和那些,但是另外的标准(动脉的血血氧不足) 都没被定义为 lHPS 盒子。HPS 频率,敏感,积极、否定的预兆的价值临床并且帕拉临床的特征被学习。结果:十(18.5%) 并且七(13%) 盒子分别地有临床、无临床症状的 HPS。最普通的病原学是肝炎 B。呼吸困难(100%) 和青紫(90%) 是最流行的临床的特征。呼吸困难并且打分别地是最敏感、特定的临床的特征。没有重要关系被发现在之间 HPS 和脾大,腹水,浮肿,黄疸,尿少,和并行的静脉。HPS 在肝炎 B 是更流行的。PaO (2 )<
70 并且动脉牙槽的坡度在 HPS 病人有最高的敏感。正统说法特性是 100% 。结论:与 75% 的否定预兆的价值(NPV ) 与 75% 的积极预兆的价值(PPV ) 和呼吸困难打是在 HPS 的诊断的最好的临床的因素症候群。PaO (2 )<
70 并且 P (A-a ) O (2 )>
30 并且他们的和,是在 HPS 病人的最珍贵的否定、积极的预兆的价值。 | Amir Houshang MohammadAlizadeh Seyed Reza Fatemi Vahid Mirzaee Manoochehr Khoshbaten Bahman Talebipour Afsaneh Sharifian Ziba Khoram Mohammad Reza Zali Farhad Haj-sheikh-oleslami MasoomehGholamreza-shirazi | 2006 | World Journal of Gastroenterology2006，12，12： | 12 |
| 3 | Effects of high voltage electrical stimulation on the rate of pH decline,meat quality and color stability in chilled beef carcasses显示文摘Objective:To determine the effects of high voltage electrical stimulation(HVES,800 Voltage)on rapid decreases in pH values and improvements in meat quality.Methods:A total of SO beef carcasses were applied,divided into two groups,one as a control and another for HVES.Meat quality was evaluated based on M.hngissimus dorsi by examining pH and temperature leveb at 1,2,5,10 and 24 h,while color stability was examined seven days after slaughter.Results:HVES decreased the pH values of the meat and accelerated rigor mortis(P<0.05).HVES caused differences in instrumental color values compared with the control groups across the ageing period at 4℃.Conclusion:the HVES had positive effects on meat quality and color stability,in contrast to undesirable consumer preferences. | Ehsan Gharib Mombeni Manoochehr Gharib Mombeini Lucas Chaves Figueiredo Luciano Soares Jacintho Siqueira Debora Testoni Dias | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 4 |
| 4 | Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: Results of a colonoscopy based study显示文摘AIM: To estimate the prevalence of colorectal cancer (CRC) in patients with long lasting colonic symptoms undergoing total colonoscopy; and to establish clinical features predicting its occurrence. METHODS: This prospective study was carried out in Imam Hospital, Tabriz University of medical sciences, Iran. Continuous patients with long lasting lower gastrointestinal tract symptoms who had the criteria of a colonoscopy were included. The endoscopist visualized the caecum documented by a photo and/or a specimen from terminal ileum. RESULTS: Four hundred and eighty consecutive symptomatic patients [mean age (SD): 42.73 (16.21)] were included. The prevalence of colorectal neoplasia was 15.3% (34 subjects) and 37.7% (181 subjects) had a completely normal colon. Adenomatous polyps were detected in 56 (11.7%) patients, in 12.3% of men and 10.9% of women. The mean age of the patients with a polyp was significantly higher than the others (49.53 ± 14.16 vs 41.85 ± 16.26, P = 0.001). Most of the adenomatous polyps were left sided and tubular; only 22.5% of polyps were more than 10 mm. Cancer was detected in 16 (3.6%) of our study population, which was mostly right sided (57.2%). The mean age of patients with cancer was significantly higher than the others (60.25 ± 8.26 vs 42.13 ± 16.08, P < 0.005) and higher than patients with polyps [60.25 (8.26) vs 49.53 (1.91) (P < 0.0005)]. None of the symptoms (diarrhea, abdominal pain, rectal bleeding, constipation, altering diarrhea and constipation, history of cancer, known irritable bowel disease, history of polyp and fissure or family history of cancer) were predictors for cancer or polyps, but the age of the patient and unexplainedanemia independently predicted cancer. CONCLUSION: Less advanced patterns and smaller sizes of adenomas in Iran is compatible with other data from Asia and the Middle East, but in contrast to western countries. Prevalence of colonic neoplasia in our community seems to be lower than that in western population. Colonic symptoms are not predictors for polyps or cancer but unexplained anemia and elder age can predict CRC. | Yousef Bafandeh Manoochehr Khoshbaten Amir Taher Eftekhar Sadat Sara Farhang | 2008 | World Journal of Gastroenterology2008，14，10： | 2 |
| 5 | Effect of soil pore size distribution on plant-available water and least limiting water range as soil physical quality indicators显示文摘Soil pore size distribution(SPSD) is one of the most important soil physical properties. This research investigated the relationships of location and shape parameters of the SPSD curves with plant-available water(PAW) and least limiting water range(LLWR) of the light-textured soils at the Torogh Agricultural Research Station in north-eastern Iran. Soil moisture release curve(SMRC), PAW and LLWR in matric heads of 100 and 330 h Pa for the field capacity and location and shape parameters of the SPSD curves of 30 soils with different texture and organic carbon contents were determined, and the variable relationships were statistically analyzed. The results showed that the median equivalent pore diameter(de), mean de, standard deviation(SD*), and skewness of the SPSD curves were significantly correlated with PAW(PAW330) and LLWR(LLWR330) measured in a matric head of 330 h Pa. Decrease in deand increase in the diversity of soil pore size(SD*) increased PAW330 and LLWR330. The SD* values of all the soil samples were lower than the optimal ranges suggested in literature. Neither PAW nor LLWR values were significantly different in the soils with the optimal modal deand those with non-optimal modal de. Optimal values of median and mean equivalent pore diameters and kurtosis of SPSD curves led to a significant improvement of PAW330 and LLWR330 as soil physical quality indicators. It was recommended to revise the optimal ranges for SD* and modal defor future studies. | Mehdi ZANGIABADI Manoochehr GORJI Mehdi SHORAFA Saeed KHAVARI KHORASANI Saeed SAADAT | 2020 | Pedosphere2020，30，2： | 2 |
| 6 | Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis显示文摘 | Shiva Mohammadzadeh Mohammad Shariatpanahi Manoochehr Hamedi Reza Ahmadkhaniha Nasrin Samadi Seyed Nasser Ostad | 2006 | Food Chemistry2006，，4： | 2 |
| 7 | An Integrated Framework for Post-ISO 9000 Quality Development显示文摘 | Manoochehr N Dennis F K | 2000 | International Journal of Quality & Reliability Management2000，17，3： | 1 |
| 8 | Alteration of ADP-ribosylation in aging rat brain astrocytes显示文摘DNA damage and the enzyme poly(ADP-ribose)polymerase(PARP)associated with the pathogenesis of numerous age-related neurodegenerative disorders.Astrocytes play crucial roles in both support metabolic functions and cell viability of the brain.PARP regulates DNA damage and repair in the brain cells.In this study PARP activity and DNA strand break were investigated in the astrocytes isolated from young and aged rat brain.Three and 30-month-old rats were killed by decapitation and brains were removed onto an ice cooled glass plate.Astrocytes were isolated by sucrose density gradient centrifugation and glutamine synthetase(GS)served as a marker of the astrocytes lineage.The specific activity of PARP was assayed in permeabilized cells by measuring the incorporation of the ADP-ribose moiety of[3H]NAD into the nuclear acceptor proteins.The rate of DNA strand breaks was determined using a fluorescent dye and monitored spectrofluorimetry.An increase(about 75%)in the PARP activity was observed in the whole homogenates of aged rats,whereas this rise was more pronounced(about 360%)when the reaction was measured in the purified astrocyte preparations.The amount of DNA strand breaks was also higher in the astrocytes isolated from the aged brain as compared to that of young levels.The close relationship between the level of DNA strand breaks and PARP activity in the astrocytes suggest that these cells are susceptible to the metabolic alterations in aging.It is concluded that the astrocytes PARP might be considered as a therapeutic target for combating age related neurodegenerative disorders. | Manoochehr MESSRIPOUR Azadeh MESRIPOUR | 2019 | BIOCELL2019，43，1： | 1 |
| 9 | Effect of vanadyl sulfate on fructose-induced insulin resistance rat显示文摘 | Mehdi H Mohsen A Manoochehr M | 2003 | Iranian Biomedi J2003，7，4： | 1 |
| 10 | Bayesian Estimation of Generalized Half Logistic Distribution under Progres-sive Type-II Censored显示文摘 | Reza Azimi Farhad Yaghmaei Manoochehr Babanezhad | 2012 | Applied Mathematical Sciences2012，，106： | 1 |
| 11 | New immunological investigations on Helicobacter pylori ‐induced gastric ulcer in patients显示文摘 | Hamid Reza Rahimi Manoochehr Rasouli Akram Jamshidzadeh Shohreh Farshad Mehdi Saberi Firoozi Ali Reza Taghavi Simin Kiany | 2013 | Microbiol Immunol2013，，6： | 1 |
| 12 | Cytokine Profiles and Cell Proliferation Responses to Truncated ORF2 Protein in Iranian Patients Recovered from Hepatitis E Infection显示文摘 | Reza Taherkhani Fatemeh Farshadpour Manoochehr Makvandi Hamid Rajabi Memari Ali Reza Samarbafzadeh Nasrin Sharifi Behrouz Naeimi Saeed Tajbakhsh Samad Akbarzadeh Susana A. Laucella | 2015 | Journal of Tropical Medicine2015，，： | 1 |
| 13 | Design and production of a multiepitope construct derived from hepatitis E virus capsid protein显示文摘 | Reza Taherkhani Fatemeh Farshadpour Manoochehr Makvandi | 2015 | J. Med. Virol2015，，7： | 1 |
| 14 | The role of performance measurement systems in promoting quality development beyond ISO 9000显示文摘 | Manoochehr Najmi Dennis F. Kehoe | 2001 | International Journal of Operations & Production Management2001，，1： | 1 |
| 15 | Prevalence of Hepatitis E Virus among Adults in South-West of Iran显示文摘 | Fatemeh Farshadpour Reza Taherkhani Manoochehr Makvandi Piero Luigi Almasio | 2015 | Hepatitis Research and Treatment2015，，： | 1 |
| 16 | Association of sporadic breast cancer with PTEN/MMAC1/TEP1 promoter hypermethylation 显示文摘 | Sadeq V Isar N Manoochehr T | 2011 | Med Oncol2011，28，2： | 1 |
| 17 | REDUCTION OF STILLING BASIN LENGTH WITH TALL END SILL显示文摘Experiments were conducted to characterize forced hydraulic jumps in stilling basins for enforced cases due to tail water level or dam site arrangement and construction.The case with a single tall sill was simulated in a horizontal flume downstream of a sluice gate.Results of experiments are compared with the classical hydraulic jump, and significant effect of tall sill on dissipation of energy in shorter distance was confirmed.Furthermore, the generated jumps were classified based on the ratio of sill height to basin length, and a simple design criterion was proposed to estimate the basin length for a desired jump and particular inflow. | FATHI-MOGHADAM Manoochehr HAGHIGHIPOUR Sadegh LASHKAR-ARA Babak AGHTOUMAN Peyman | 2011 | Journal of Hydrodynamics2011，23，4： | 1 |
| 18 | A framework to review Performance Prism显示文摘 | Najmi Manoochehr Etebari | 2012 | International Journal of Operations&Production Management2012，3210，： | 1 |
| 19 | A framework to review performance measurement systems 显示文摘 | Manoochehr Najmi John Rigas Ip-Shing Fan | 2005 | Business Process Management Journal2005，11，2： | 1 |
| 20 | Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis 显示文摘 | Shiva M Mohammad S Manoochehr H | 2007 | Food Chemistry2007，103，2007： | 1 |
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