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	题名	作者	年代	出处	被引量
1	Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase显示文摘AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse small intestine.METHODS:For this study,primary culture of ICCs was prepared from the small intestine of the mouse.LPS was treated to the cells prior to measurement of the membrane currents by using whole-cell patch clamp technique.Immunocytochemistry was used to examine the expression of the proteins in ICCs.RESULTS:LPS suppressed the pacemaker currents of ICCs and this could be blocked by AH6809,a prostaglandin E2-EP2 receptor antagonist or NG-Nitro-Larginine Methyl Ester,an inhibitor of nitric oxide(NO) synthase.Toll-like receptor 4,inducible NO synthase or cyclooxygenase-2 immunoreactivity by specific antibodies was detected on ICCs.Catalase(antioxidant agent) had no action on LPS-induced action in ICCs.LPS actions were blocked by nuclear factor kB(NF-kB) inhibitor,actinomycin D(a gene transcription inhibitor),PD 98059(a p42/44 mitogen-activated protein kinases inhibitor) or SB 203580 [a p38 mitogen-activated protein kinases(MAPK) inhibitor].SB 203580 also blocked the prostaglandin E2-induced action on pacemaker currents in ICCs but not NO.CONCLUSION:LPS inhibit the pacemaker currents in ICCs via prostaglandin E2-and NO-dependent mechanism through toll-like receptor 4 and suggest that MAPK and NF-kB are implicated in these actions.	Dong Chuan Zuo Seok Choi Pawan Kumar Shahi Man Yoo Kim Chan Guk Park Young Dae Kim Jun Lee In Yeoup Chang Insuk So Jae Yeoul Jun	2013	World Journal of Gastroenterology2013，19，8：	9
2	Increased incidence of early de novo cancer in liver graft recipients treated with cyclosporine: An association with C显示文摘	Angela S. W. Tjon Jerome Sint Nicolaas Jaap Kwekkeboom Robert A. de Man Geert Kazemier Hugo W. Tilanus Bettina E. Hansen Luc J. W. van der Laan Thanyalak Tha‐In Herold J. Metselaar	2010	Liver Transpl2010，，7：	2
3	Microstructure and situ synthesized TiC/Ti surface MMC on Ti-6Al-4V by laser cladding 显示文摘	Man H C Zhang S Cheng formation mechanism of in F T	2001	Scripta Mater2001，44，：	1
4	Parkinson' s Disease and Aging: Changes of Somatosensory Evoked Potentials in Humans显示文摘	Man'kovskil NB Karaban' IN Mialovitskaia EA	1994	Neurophysiology1994，26，2：	1
5	Partial escape of angiotensin converting enzyme (ACE)inhibition during prolonged ACE inhibitor treatment:does it exist and does it affect the antihypertensive response?显示文摘	Van den Meiracker AH Man in 't Veld AJ Admiraal PJ	1992	J Hypertens1992，10，8：	1
6	High plasma prorenin in diabetes mellitus and its correlation with some complications 显示文摘	Franken A A Derkx F H Man in' tVeld A J	1990	J Clin Endocrinol Metab1990，71，4：	1
7	Double-blind placebo-controlled study df ibopamine and digoxin in patients with mild to moderate heart failure:results of the Dutch Ibopamine Multicenter Trial (DIMT)显示文摘	van Veldhuisen DJ Man in Veld A J	1993	J Am Coll Cardiol1993，22，：	1
8	Preparation and properties of sulfonated poly(arylene ether sulfone)/hydrophilic oligomer-g-CNT composite membranes for PEMFC 显示文摘	In Hyouk Sung Duk Man Yu Young Jun Yoon	2013	Macro- molecular Research2013，21，10：	1
9	Conceptual and basic designs of the Mobile Harbor crane based on topology and shape optimiz- ation显示文摘	In Gwun Jang Kyung-Soo Kim Byung Man Kwak	2014	Struct Multidisc Optim2014，，50：	1
10	Correlation between positive-electrode morphology and sulfur utilization in lithium-sulfur battery显示文摘	Nam In Kim Chae Bong Lee Jae Man Seo		0，，1：	1
11	Novel evidence of the occurrence of NAD (P)H oxidase activity 显示文摘	Piccoli C Ria R Scrima R et ah Characterization of mitochon- drial and extra-mitochondrial oxygen consuming reactions in hu- man hematopoietic stem cells	2005	J Biol Chem2005，280，26：	1
12	Employment calorimetry in detect- virgin coconut oil 显示文摘	Mansor T S T Che Man Y B of differential scanning ing lard adulteration in Journal of the American Shuhaimi M	2012	Oil Chemists''Society2012，89，3：	1
13	Partial escape of angiotensin converting enzyme (ACE) inhibition during prolonged ACE inhibitor treatment: does it exist and does it affect the antihypertensive response? 显示文摘	Van den Meiracker AH Man in't Veld A J Admiraal PJ	1992	J Hypertens1992，10，8：	1
14	Sponcly loarthritisresearch Consortium of Canada magnetic resonance imaging index forassessment of sarroiliar joint in flammation in ankylosing spondylitis显示文摘	Maksymowych W F In man R D Salonen D	2005	Arthritis Rheum2005，53，5：	1
15	Process development for heine-enriched peptide by enzymatic hydrolysisof hemoglobin显示文摘	Man Jin In Hee Jeong Chae Nam Soon Oh	2002	Bioresource Technology2002，，84：	1
16	Multiple cerebral arterial occlusions related to Mycoplasma pneumoniae infection显示文摘	Manyong Lee In Soo Joo Seong-Joon Lee Ji Man Hong Jin Soo Lee	2013	Neurological Sciences2013，，4：	1
17	Health-related quality of life in children with newly diagnosed immune thrombocytopenia 显示文摘	See comment in PubMed Commons belowHeitink-Polle KM1 Haver- man L Annink KV	2014	Haematologi- ca2014，99，9：	1
18	Vibration Control of Bridges Under Moving Loads 显示文摘	Ho - Chul Kwon Man - Cfeol Kim In - Won Lee	1998	Computer & Structures1998，166，4：	1
19	1 gene (KCNJ10) 显示文摘	Haj-Yssein NN Jensen V Vindedal GF : Evi- dence that compromised K spatial buffering contrib- utes to the epileptogenic effect of mutations in the hu- man Kir 4	2011	Gila2011，59，11：	1
20	CIA' s Kent School: Improving Training for New Analysts 显示文摘	Stephen Man'in	2003	International Journal of Intelligence and Counterintelligence2003，16，4：	1

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