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| 1 | Effects of carob-bean gum thickened formulas on infants' reflux and tolerance indices显示文摘AIM: To examine the effect of carob-bean gum(CBG) thickened-formulas on reflux and tolerance indices in infants with gastro-esophageal reflux(GER). METHODS: Fifty-six eligible infants(1-6 mo old) were randomly allocated to receive for two weeks a formula with either 0.33 g/100 m L(Formula A) or 0.45 g/100 m L(Formula B) of cold soluble CBG galactomannans respectively, or a formula with 0.45 g/100 m L of hot soluble CBG galactomannans(Formula C). No control group receiving standard formula was included in the study. Data on the following indices were obtained both at baseline and follow-up from all study participants: 24 h esophageal p H monitoring indices, anthropometrical indices(i.e., body weight and length) and tolerance indices(i.e., frequency of colics; type and frequency ofdefecations). From the eligible infants, forty seven were included in an intention-to-treat analysis to examine the effects of the two-week trial on esophageal 24 h p H monitoring, growth and tolerance indices. Repeated Measures ANOVA was used to examine the research hypothesis.RESULTS: Regarding changes in 24 h p H monitoring indices, significant decreases from baseline to followup were observed in the 'Boix Ochoa Score'(i.e., an index of esophageal acid exposure), in the total number of visible refluxes and in all symptoms related indices due to acid reflux only for infants provided with Formula A, while no significant changes were observed for infants provided with Formulas B and C. In addition, the significant decreases observed in two symptoms related p H monitoring indices(i.e., 'Symptom index for reflux' and 'Percentage of all reflux') for infants provided with Formula A were also found to differentiate significantly compared to the changes observed in the other two groups(P = 0.048 and P = 0.014 respectively). Concerning changes in anthropometric indices, body weight significantly increased among infants provided with Formulas A and C, but not for infants provided with Formula B. As far as tolerance indices were concerned, the numbers of total and diarrheic defecations increased significantly only in infants provided with Formula B and these changes were significantly higher compared to the decreases observed in infants fed with Formulas A and C(P = 0.003 and P = 0.015 respectively. Lastly the number of colics significantly decreased in all infants, irrespective of the tested formula. CONCLUSION: Formula A(i.e., 0.33 g/100 m L of cold galactomannans) was effective in reducing certain p Hmonitoring indices of uncomplicated GER, increased body weight and was well-tolerated by infants. | Miglena Georgieva Yannis Manios Niya Rasheva Ruzha Pancheva Elena Dimitrova Anne Schaafsma | 2016 | World Journal of Clinical Pediatrics2016，5，1： | 2 |
| 2 | Cardiometabolic risk through an integrative classification combining physical activity and sedentary behavior in European adolescents:HELENA study显示文摘Purpose: This study aims to compare adolescents' cardiometabolic risk score through an integrative classification of physical activity(PA),which involves the combination of moderate-to-vigorous physical activity(MVPA) and sedentary behavior(SB).Methods: A cross-sectional study derived from the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study database(2006-2008) was conducted in adolescents(n = 548; boys, 47.3%; 14.7 ± 1.2 years) from 10 European cities. MVPA and SB were objectively measured using accelerometry. Adolescents were divided into 4 categories according to MVPA(meeting or not meeting the international recommendations) and the median of SB time(above or below sex-and age-specific median) as follows: High-SB & Inactive, Low-SB & Inactive,High-SB & Active, and Low-SB & Active. A clustered cardiometabolic risk score was computed using the homeostatic model assessment, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol, sum 4 skinfolds, and cardiorespiratory fitness(CRF).Analyses of covariance were performed to discern differences on cardiometabolic risk scores among PA categories and each health component.Results: The cardiometabolic risk score was lower in adolescents meeting the MVPA recommendation and with less time spent in SB in comparison to the high-SB & Inactive group(p < 0.05). However, no difference in cardiometabolic risk score was established between High-SB or Low-SB groups in inactive adolescents. It is important to note that CRF was the only variable that showed a significant modification(higher)when children were compared from the category of physically inactive with 'active' but not from high-to low-SB.Conclusion: Being physically active is the most significant and protective outcome in adolescents to reduce cardiometabolic risk. Lower SB does not exhibit a significant and extra beneficial difference. | Carlos Cristi-Montero Palma Chillón Idoia Labayen José A.Casajus Marcela Gonzalez-Gross Jérémy Vanhelst Yannis Manios Luis A.Moreno Francisco B.Ortega Jonatan R.Ruiz | 2019 | Journal of Sport and Health Science2019，8，1： | 2 |
| 3 | Time Rate of Blood Pressure Variation Is Associated With Increased Common Carotid Artery Intima-Media Thickness显示文摘 | Nikos A. Zakopoulos Georgios Tsivgoulis Gerassimos Barlas Christos Papamichael Konstantinos Spengos Efstathios Manios Ignatios Ikonomidis Vassilios Kotsis Ioanna Spiliopoulou Konstantinos Vemmos Myron Mavrikakis Spyridon D. Moulopoulos | 2005 | Hypertension2005，，4： | 2 |
| 4 | Accurate Assessment of Patient Effective Radiation Dose and Associated Detriment Risk From Radiofrequency Catheter Ablation Procedures显示文摘 | Kostas Perisinakis John Damilakis Nicholas Theocharopoulos Emmanouel Manios Panayiotis Vardas Nicholas Gourtsoyiannis | 2001 | Circulation: Journal of the American Heart Association2001，，1： | 2 |
| 5 | Fibroblast growth factor-23 (FGF-23) and the kidney显示文摘 | Tsaglis G Psimenou E Manios E | 2009 | Int J Artif Organs2009，32，： | 1 |
| 6 | Factors influencing secondary preventive blood pressure control in hypertensive stroke patients显示文摘 | Spengos K Tsivgoulis G Manios E | 2005 | Nervenarzt2005，76，2： | 1 |
| 7 | The role of the post-cardioversion time course of hs-CRP levels in clarifying the relationship between inflammation and persistence of atrial fibrillation显示文摘 | KALLERGIS E M MANIOS E G KANOUPAKIS E M | 2008 | Heart2008，94，： | 1 |
| 8 | Changes in atrial electrical properties following cardioversion of chronic atrial fibrillation : Relation with recurrence显示文摘 | Manios EG Kanoupakis EM Chlouverakis GI | 2000 | Cardiovascular Research2000，47，2： | 1 |
| 9 | 进食频率预测新发高血压及血压、动脉硬化和脉搏波反射进展率显示文摘普遍认为每天至少吃3餐,但现代生活方式正逐渐打破既往进食习惯。已发现每日进食频率可能影响多种心血管代谢风险因素,但尚未深入研究其临床价值。研究显示,与进食次数较少者相比,进食次数较多者通常血脂状况更好,胰岛素抵抗及代谢综合征发病风险更低。进食频率增加使空腹时间减少,平均血糖浓度及胰岛素分泌量降低。胰岛素浓度降低使羟甲基戊二酸单酰辅酶A还原酶活性降低,从而减少肝脏胆固醇合成。 | Karatzi K Georgiopoulos G Yannakoulia M Efthimiou E Voidonikola P Mitrakou A Manios E Alevizaki M Papamichael C Stamatelopoulos K 曲浥晨 | 2016 | 中华高血压杂志2016，24，5： | 1 |
| 10 | Impact of prehypertension oncarotid artery intima-media thickening:actual or masked显示文摘 | Manios E Michas F Tsivgoulis G | 2011 | Athero-sclerosis2011，214，1： | 1 |
| 11 | Sewage sludge composting on the island of Crete显示文摘 | MANIOS T MANIADAKIS K FRANTZESKAKI N | 2003 | Biocycle2003，44，6： | 1 |
| 12 | Impact of prehyperten- sion on common carotid artery intima-media thickness and left ven- tricular mass 显示文摘 | Manios E Tsivgoulis G Koroboki E | 2009 | Stroke2009，40，： | 1 |
| 13 | Comparison of noninvasive oscillometric and intra-arterial blood pressure measurements in hyperacute strokd显示文摘 | Manios E Vemmos K Tsivgoulis G | 2007 | Blood Press Monit2007，12，： | 1 |
| 14 | Surveying the response of transport channels of intact RBC membranes upon AgNO3 administration:an atomic force microscopy study显示文摘 | Stamopoulos D Manios E Gourni E | | 0，，1： | 1 |
| 15 | Comparison of noninvasive oscillometric and intra-arterial blood pressure measurements in hyperacute strokd显示文摘 | Manios E Vemmos K Tsivgoulis G | 2007 | Blood Press Monit2007，12，3： | 1 |
| 16 | Evaluation of a Health and nutrition education program in primary school children of crete over a three - year period 显示文摘 | Yannis Manios | 1999 | Preventive Medicine1999，，28： | 1 |
| 17 | Determinants of childhood obesity and association with maternal perceptions of their children's weight status:the 'genesis”study显示文摘 | Manios Y Moschonis G Grammatikaki E | | 0，，10： | 1 |
| 18 | Extracellular matrix alterations in patients with paroxysmal and persistent atrial fibrillation:biochemical assessment of collagen type-I turnover显示文摘 | Kallergis E M Manios E G Kanoupakis E M | 2008 | J Am Coll Cardiol2008，52，3： | 1 |
| 19 | Removal of heavy metals from a metaliferous water solution by Typha latifolia plants and sewage sludge copost显示文摘 | MANIOS T STENTIFORD E I MILLNER P | 2003 | Chemosphere2003，53，： | 1 |
| 20 | (001) Textured CoPt/Ag films and nanocomposites: the effect of Ag underlayers 显示文摘 | Manios E Karanasos V Niarchos D | 2004 | J Magn Magn Mater2004，，： | 1 |
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