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132篇 您的检索式:作者名="Manning D G"
    题名 作者 年代 出处 被引量
1Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels 2010World Journal of Gastroenterology2010,16,6:11
2Diversification and spectral tuning in marine proteorhodopsins显示文摘Man D Wang W Sabehi G 2003European Molecular Biology Organization2003,22,8:1
3Occupational slip,trip, and fall- related injuries- can the contribution of slipperiness be isolated 显示文摘Courtney T K Sorock G S Manning D P 2001Ergonomics2001,44,13:1
4A comparison of Entecavir and lamivtldine for HBeAg-positive chronic Hepatitis B显示文摘Chang T T Gish R G Man R D 2006N Engl Med2006,354,10:1
5Estimating source regions of European emissions of trace gases from observations at Mace Head 显示文摘Ryall D B Derwent R G Manning A J 2001Atmospheric Environment2001,35,14:1
6A luciferase reporter gene assay and aryl hydrocarbon receptor 1 genotype predict the LD50 of polychlorinated biphenyls in avian species显示文摘Manning G E Farmahin R Crump D 2012Toxicology and Applied Pharmacology2012,263,3:1
7Determination ofsedimentation rate of a recently deposited tidal flat, western coast of Korea, using 1RSL dating显示文摘HONG D G MAN S C HAN J H CttEONG C S 2003Quaternary Science Reviews2003,22,22:1
8The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M 2010Science2010,330,6010:1
9The epidemiology of Leber hereditary optic neuropathy in the North East of England显示文摘Man P Y Griffiths P G Brown D T 2003Am J Hum Genet2003,72,:1
10The development of deck assessment by radar and thermography显示文摘Manning D G Holt F B 1986Transportation Research Board1986,1083,:1
11Micronucleus frequency in lymphocytes and 8-hydroxydeoxyguanosine level in plasma of women with polycystic ovary syndrome显示文摘Zuhal Hamurcu Fahr? Bayram Güven Kahr?man Ham?yet D?nmez-Altuntas Gülden Baskol 2010Gynecological Endocrinology2010,,8:1
12Corrosion and electrical impedance in concrete显示文摘HOPE B B IP A K MANNING D G 1985Cement and Concrete Research1985,15,3:1
13显示文摘Chambard G Man P D Klumperman B 2000Macromol Symp2000,150,:1
14Health insur-ance and the demand for medical care:evidence from a ran-domized exper iment 显示文摘Manning W G Newhouse J P Naihua D 1987American Economic Review1987,77,3:1
15Deficiency of PPAR beta/delta in the epidermis results in defective cuta- neous permeability barrier homeostasis and increased inflam- marion 显示文摘Man M Q Barish G D Schmuth M 2008J Invest Dermato12008,128,2:1
16显示文摘Cotter D Burt M G Manning R J 1992Phys Rew Lett1992,68,8:1
17Preparation of MgO and Fe nanostructure in Mg matrix composite by reaction sintering显示文摘MAN G LANG J NG D H L 2005Composites Science and Technology2005,36,9:1
18Preparation and some properties of 1,1,1-trihalo-2-alkanols显示文摘Bal' on Y G Shul' man M D Vakulenko L I 1989J Org Chem1989,25,7:1
192003 Estimating European emissions of ozone-depleting and greenhouse gases using observations and a modeling back-attribution technique显示文摘Manning A J Ryall D B Derwent R G 2003Journal of Geophysical Research2003,108,14:1
20Formulation of Rayleigh damping and its extensions 显示文摘Man liu Gorman D G 1995Computers & Structures1995,57,2:1
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