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175篇 您的检索式：作者名="Manning G S"

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	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Thrombospondin 1,a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy显示文摘	Bocci G Francia G Man S	2003	Proc Natl Acad Sci USA2003，100，12：	1
3	Occupational slip,trip, and fall- related injuries- can the contribution of slipperiness be isolated 显示文摘	Courtney T K Sorock G S Manning D P	2001	Ergonomics2001，44，13：	1
4	Relaxed elastic line on a curved surfaces显示文摘	Manning G S	1987	Quarterly of Applied Mathematics1987，，3：	1
5	Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water显示文摘	Man S Bocci G Francia G	2002	Cancer Res2002，62，10：	1
6	Molecular characterization of Brucella abortus chromosome Ⅱ recombination显示文摘	Tsoktouridis G Merz C A Manning S P	2003	J Bacteriol2003，185，20：	1
7	Intrinsic equations for an relaxed elastic line on a oriented surface显示文摘	Nickerson H K Manning G S	1988	Geometriae Dedicata1988，27，：	1
8	Electrostatic free energy of the DNA double helix in counterion condensation theory显示文摘	MANNING G S	2002	Biophys Chem2002，，：	1
9	Gene Expression in the Pulp of Ripening Ba-nanas显示文摘	ROSYBEL M S MANNING K FLETCHER J AKED J BIRD CR SEYMOUR G B	1997	Plant Physiol1997，115，：	1
10	Determination ofsedimentation rate of a recently deposited tidal flat, western coast of Korea, using 1RSL dating显示文摘	HONG D G MAN S C HAN J H CttEONG C S	2003	Quaternary Science Reviews2003，22，22：	1
11	Increased plasma vascular endothelial growth factor (VEGF) as a surrogate marker for optimal therapeutic dosing of VEGF receptor-2 monoclonal antibodies显示文摘	Bocci G Man S Green SK	2004	Cancer Res2004，64，18：	1
12	The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘	International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M	2010	Science2010，330，6010：	1
13	The effect of 3 versus 6 years of zoledronic acid treatment of osteoporosis:a randomized extension to the HORIZON-Pivotal Fracture Trial(PFT)显示文摘	Black DM Reid IR Boonen S Bucci-Rechtweg C Cauley JA Cosman F Cummings SR Hue TF Lippuner K Lakatos P Leung PC Man Z Martinez RL Tan M Ruzycky ME Su G Eastell R		0，，：	1
14	Solving the knapsack problem for adaptive multimedia systems显示文摘	Khan S Li K F Manning E G	2002	Stud Inform2002，2，1：	1
15	The significance of perineural invasion as a prognostic factor in patients with gastric carcinoma 显示文摘	Duraker N ~i~man S Can G	2003	Surgery Today2003，33，2：	1
16	Antitumor effects in mice of low- dose (metronomic) cyclophosphamide administered continuously through the drinking water显示文摘	Man S Bocci G Francia G	2002	Cancer Res2002，62，10：	1
17	Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts显示文摘	du Manoir JM Francia G Man S	2006	Clin Cancer Res2006，12，31：	1
18	Thrombospondin 1,a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy显示文摘	Bocci G Francia G Man S	2003	Proc Natl Acad Sci USA2003，100，12：	1
19	Antitumor effects in mice of low-dose(metronomic) cyclophosphamide administered continuously through the drinking water 显示文摘	Man S Bocci G Francia G	2002	Cancer Res2002，62，10：	1
20	Antitumor effects in mice of low-dose(metronomic)cyclophosphamide administered continuously through the drinking water显示文摘	Man S Bocci G Francia G	2002	Cancer Res2002，62，：	1

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