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| 1 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 2 | Marine ecoregions of the world:a bioregionalization of coastal and shelf areas显示文摘 | Spalding MD Fox HE Allen GR Davidson N Ferdafia ZA Finlayson M Halpern BS Jorge MA Lombana AL Lourie SA Martin KD Manus EC Molnar J Recchia CA Robertson J | | 0，，： | 1 |
| 3 | Tarcolimus rescue for resistant rejection,chronic rejection and immunoglobulin a nephropathy of renal allografts under primag cyclosprorine a immunosuppression显示文摘 | Manu MA Tanabe K Ishikawa N | 1999 | Transplant Proc1999，31，： | 1 |
| 4 | Renal transplantationsubstituti on therapy in advanced stage uremia显示文摘 | Sinescu I Manu MA Harza M | 2008 | J Med Life2008，1，2： | 1 |
| 5 | Related articles comparative study of helical CT scan angiography,conventional arteriography,and intraoperative findings for the evaluation of living renal transplant donors显示文摘 | Harza M Manu R | 2001 | Transplant Proc2001，33，12： | 1 |
| 6 | Comparative study of helical CT scan angiography, conventional arteriography, and intraoperative findings for the evaluation of living renal transplant donors 显示文摘 | Manu MA Harza M Manu R | 2001 | Transplant Proc2001，33，1： | 1 |
| 7 | Tacrolimus rescue for resistant rejection, chronic rejection, and immunoglobulin A nephropathy of renal allografts under primary cyclosporine A imrnu- nosuppression显示文摘 | Manu MA Tanabe K Ishikawa N | 1999 | Transplant Proc1999，31，7： | 1 |
| 8 | Related articles comparative study of helical CT scan angiography, conventional arteriography, and intraoperative findings for the evaluation of living renal transplant donors显示文摘 | Harza M Manu R | 2001 | Transplant Proc2001，33，12： | 1 |
| 9 | Comparative Study of Helical CT Scan Angiography,Conventional Arteriography,and Intraoperative Findings for the Evaluation of Living Renal Transplant Donors显示文摘 | Manu MA Harza M Manu R | 2001 | Transplant Proc2001，33，12： | 1 |
| 10 | Heavy metals distribution in an Iowa suburban landscape显示文摘 | LANGNER AN MANU A TABATABAI MA | 2010 | Journal of Environmental Quality2010，40，1： | 1 |
| 11 | Quality of life assessed by SF- 36 health survey transplant patients 显示文摘 | Manu MA Rasulescu S Harza M | 2001 | Transplantation Proceedings2001，33，： | 1 |
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