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| 1 | Genotyping-by-sequencing of pear (Pyrus spp.) accessions unravels novel patterns of genetic diversity and selection footprints显示文摘Understanding of genetic diversity and marker-trait relationships in pears(Pyrus spp.)forms an important part of gene conservation and cultivar breeding.Accessions of Asian and European pear species,and interspecific hybrids were planted in a common garden experiment.Genotyping-by-sequencing(GBS)was used to genotype 214 accessions,which were also phenotyped for fruit quality traits.A combination of selection scans and association analyses were used to identify signatures of selection.Patterns of genetic diversity,population structure and introgression were also investigated.About 15000 high-quality SNP markers were identified from the GBS data,of which 25%and 11%harboured private alleles for European and Asian species,respectively.Bayesian clustering analysis suggested negligible gene flow,resulting in highly significant population differentiation(Fst=0.45)between Asian and European pears.Interspecific hybrids displayed an average of 55%and 45%introgression from their Asian and European ancestors,respectively.Phenotypic(firmness,acidity,shape and so on)variation between accessions was significantly associated with genetic differentiation.Allele frequencies at large-effect SNP loci were significantly different between genetic groups,suggesting footprints of directional selection.Selection scan analyses identified over 20 outlier SNP loci with substantial statistical support,likely to be subject to directional selection or closely linked to loci under selection. | Satish Kumar Chris Kirk Cecilia Deng Claudia Wiedow Mareike Knaebel Lester Brewer | 2017 | Horticulture Research2017，4，1： | 8 |
| 2 | In Vivo Function of Tic22, a Protein Import Component of the Intermembrane Space of Chloroplasts显示文摘进叶绿体的 Preprotein 进口在外部、内部的叶绿体信封膜(TOC 和 TIC ) 取决于 macromolecular 机械。两机械被 intermembrane 空间(IMS ) 的部件互连,这被建议。也就是说在其它之中, Tic22,二仔细联系了 isoforms 在 Arabidopsis thaliana 存在,也就是 atTic22-III 和 atTic22-IV。我们由分析相应基因的 T-DNA 插入线在 vivo 调查了 Tic22 的功能。当在单个基因的 T-DNA 插入引起了仅仅细微的缺点时,两 isoforms 的双异种在植物的光合的表演显示出延迟的生长,在热点条件下面的苍白的显型,减少的进口率,和减小。后者被变化在变异的植物的代谢物内容支持什么时候与相比野类型。因此,我们的结果支持 Tic22 直接涉及叶绿体 preprotein 进口并且可能在叶绿体生物的续生说指向到 Tic22 的特别重要性高进口率的时间的观点。 | Mareike Rudolf Anu B. Machettira Lucia E. Groβ Katrin L. Weber Kathrin Bolte Tihana Bionda Maik S. Sommer Uwe G. Maier Andreas RM. Weber Enrico Schleiff Joanna Tripp | 2013 | Molecular Plant2013，6，3： | 2 |
| 3 | Predictive Value of the High-Sen- sitivity Troponin T Assay and the Simplified Pulmonary Embolism Severity Index in Hemodynamically Stable Patients With Acute Pul- monary Embolism显示文摘 | Mareike Lankeit David Jim6nez | 2011 | Circulation Vascular Medicine2011，124，： | 1 |
| 4 | Assessing Teacher Candidates' General Pedagogical Psychological Knowledge: Test Construc- tion and Validation 显示文摘 | Thamar Voss Mareike Kunter | 2011 | Joumal of Education Psychology2011，，4： | 1 |
| 5 | Ertapenem pharmacokinetics and impact on intestinal microflora,in comparison to those of ceftriaxone,after multiple dosing in male and female volunteers显示文摘 | Mathias WR Mareike R Juergen B | 2004 | Antimicrob Agents Chemother2004，48，： | 1 |
| 6 | Association between adipinectin and mediators of inflammation in obese women显示文摘 | Stefan E Mareike F Kerstin G | | 0，，04： | 1 |
| 7 | Genetic and epigenetic control of early mouse development显示文摘 | Mareike Albert Antoine HFM Peters | 2009 | Current Opinion in Genetics & Development2009，，2： | 1 |
| 8 | Predictive Value of the High-Sensitivity Troponin T Assay and the Simplified Pulmonary Embolism Severity Index in Hemodynamically Stable Patients With Acute Pulmonary Embolism: A Prospective Validation Study显示文摘 | Mareike Lankeit David Jiménez Maciej Kostrubiec Claudia Dellas Gerd Hasenfuss Piotr Pruszczyk Stavros Konstantinides | 2011 | Circulation2011，，24： | 1 |
| 9 | Design and Implementation of A Learning Analytics Toolkit for Teachers 显示文摘 | Anna Lea Dyckhoff Dennis Zielke Mareike Bfiltmann Mohamed Amine Chatti Ulrik Schroeder | 2012 | Edueational Technology & Society2012，15，3： | 1 |
| 10 | Association between ad- ipinectin and mediators of inflammation in obese women 显示文摘 | Stefan E Mareike F Kerstin G | 2003 | Dia- betes2003，52，4： | 1 |
| 11 | Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria显示文摘 | Michaela Aichler Mareike Elsner Natalie Ludyga Annette Feuchtinger Verena Zangen Stefan K Maier Benjamin Balluff Cédrik Sch?ne Ludwig Hierber Herbert Braselmann Stephan Meding Sandra Rauser Hans Zischka Michaela Aubele Manfred Schmitt Marcus Feith Stefani | 2013 | J Pathol2013，，4： | 1 |
| 12 | Fluoride and calcium-phosphate coated sponges of the magnesium alloy AX30 as bone grafts: a comparative study in rabbits显示文摘 | Mareike Lalk Janin Reifenrath Nina Angrisani Alexandr Bondarenko Jan-Marten Seitz Peter P. Mueller Andrea Meyer-Lindenberg | 2013 | Journal of Materials Science: Materials in Medicine2013，，2： | 1 |
| 13 | Epigallocatechin Gallate Supplementation Alleviates Diabetes in Rodents显示文摘 | Swen Wolfram Daniel Raederstorff Mareike Preller | 2006 | J Nutr2006，136，： | 1 |
| 14 | Comprehensive study on regional human intestinal permeability and prediction of fraction absorbed of drug using the Ussing chamber technique显示文摘 | Sjoberg A Mareike L Tannergren C | 2013 | European Journal of Pharmaceutical Sciences2013，48，12： | 1 |
| 15 | Effects of Phytoestrogen Extracts Isolated from Pumpkin Seeds on Estradiol Production and ER/PR Expression in Breast Cancer and Trophoblast Tumor Cells显示文摘 | Dagmar Richter Sibylle Abarzua Mareike Chrobak Thomas Vrekoussis Tobias Weissenbacher Christina Kuhn Sandra Schulze MarkusS. Kupka Klaus Friese Volker Briese Birgit Piechulla Antonis Makrigiannakis Udo Jeschke Darius Dian | 2013 | Nutrition and Cancer2013，，5： | 1 |
| 16 | Ventilation Therapy for Patients Suffering from Obstructive Lung Diseases显示文摘 | Sven A. Jungblut Lena M. Heidelmann Andreas Westerfeld Hagen Frickmann Mareike K. Korber Andreas E. Zautner | 2014 | Recent Patents on Inflammation & Allergy Drug Discovery2014，，1： | 1 |
| 17 | Predictive Value of the High-Sensitivity Troponin T Assay and the Simplified Pulmonary Embolism Severity Index in Hemodynamically Stable Patients With Acute Pulmonary Embolism: A Prospective Validation Study显示文摘 | Mareike Lankeit David Jiménez Maciej Kostrubiec Claudia Dellas Gerd Hasenfuss Piotr Pruszczyk Stavros Konstantinides | 2011 | Circulation2011，，24： | 1 |
| 18 | Assessment of in situ biodegradation of monochlorobenzene in contaminated groundwater treated in a constructed wetland 显示文摘 | MAREIKE B HEMA R GWENAEL I | 2007 | Environmental Pollution2007，，148： | 1 |
| 19 | Thrombolytic therapy for submassive pulmonary em- bolism显示文摘 | Mareike L A | 2012 | Best Pract Res Clin Haematol2012，25，： | 1 |
| 20 | Rare earth elements and relation between their potential bioavailability and soil properties,Nidda catchment(Central Germany)显示文摘 | Mareike L Christian A Peter F H | 2011 | Plant Soil2011，349，1： | 1 |
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