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| 1 | How to manage inflammatory bowel disease during the COVID-19 pandemic:A guide for the practicing clinician显示文摘Managing inflammatory bowel disease(IBD)during the coronavirus disease 2019(COVID-19)pandemic has been a challenge faced by clinicians and their patients,especially concerning whether to proceed with biologics and immunosuppressive agents in the background of a global outbreak of a highly contagious new coronavirus(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2).The knowledge about the impact of this virus on patients with IBD,although it is still scarce,is rapidly evolving.In particular,concerns surrounding medications’impact for IBD on the risk of acquiring SARS-CoV-2 infection or developing COVID-19,and potentially exacerbate viral replication and the COVID-19 course,are a current thinking of both practicing clinicians and providers caring for patients with IBD.Managing patients with IBD infected with SARS-CoV-2 depends on both the clinical activity of the IBD and the occasional development and severity of COVID-19.In this review,we summarize the current data regarding gastrointestinal involvement by SARS-CoV-2 and pharmacologic and surgical management for IBD concerning this infection,and the COVID-19 impact on both the patient's psychological functioning and endoscopy services,and we concisely summarize the telemedicine roles during the COVID-19 pandemic. | Júlio Maria Fonseca Chebli Natália Sousa Freitas Queiroz Adérson Omar Mourão Cintra Damião Liliana Andrade Chebli Márcia Henriques de Magalhães Costa Rogério Serafim Parra | 2021 | World Journal of Gastroenterology2021，27，11： | 2 |
| 2 | Community outbreak of legion- naires disease : aninvestigation confirming the potential for cooling tow- er to transmit Legionella species 显示文摘 | Keller Bw Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，： | 1 |
| 3 | Community outbreak of legionnaires'disease:an investigation confirming the potential for cooling tower haring Legionella species显示文摘 | Keller Bw Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，2： | 1 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy显示文摘 | Daniel J. Klionsky Fabio C. Abdalla Hagai Abeliovich Robert T. Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A. Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizu | 2012 | Autophagy2012，，4： | 1 |
| 5 | The role of spinal neuro-immune activation in morphin tolerance/hyperalgesia in neuropath-ic and sham-operated rats显示文摘 | Vasudeva R Maria DR Joyce AD | 2002 | J Neurosci2002，22，22： | 1 |
| 6 | Community outbreak of Legionnaires'disease:An investigation confirming the potential for cooling tower to transmit Legionella species显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，25： | 1 |
| 7 | Structural basis for Hif-1a/CBP recognition in the cellular hypoxic response显示文摘 | Sonja AD Maria MY Roberto NP | 2002 | Natl Acad Sci USA2002，99，8： | 1 |
| 8 | Community outbreak of Legionnaires'disease:an investigation confirming the potential for cooling tower to transmit Legionella species显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，： | 1 |
| 9 | Role of the reacting free radicals on the antioxidant mechanism of curcumin显示文摘 | Annia G Ruslan AD Maria TR | | 0，，363： | 1 |
| 10 | Community outbreak of Legionaires disease: an investigation confirming the potential for cooling tower to transmit Legionella species 显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，2： | 1 |
| 11 | Community outbreak of Legionaires disease: An investigation confirming the potential for cooling tower to transmit Legionella species 显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，25： | 1 |
| 12 | Community outbreak of legionnaires' disease: an inrestigation confirming the potential for coding toner haring Legionella species 显示文摘 | Keller Bw Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，： | 1 |
| 13 | Prevalence of celiac disease in an urban area of Brazil with predominantly European ancestry显示文摘AIM: To determine the prevalence of celiac disease in a group of volunteer blood donors at a blood bank in the city of Curitiba, Brazil through detection of the serum marker immunoglobulin A (IgA) antitransglutaminase an-tibody.METHODS: Blood samples collected from 2086 healthy subjects at the Paraná State Center for Hematology and Hemotherapy in Curitiba were submitted to ELISA testing for the IgA antitransglutaminase antibody. Positive samples received IgA antiendomysium antibody test through indirect immunofluorescence using human umbilical cord as substrate. Subsequently, patients who were positive on both tests underwent small bowel (distal duodenum) biopsy.RESULTS: Six subjects, four males and two females, tested positive for the two serum markers. Five of the six were submitted to intestinal biopsy (one declined the procedure). Biopsy results revealed changes in the distal duodenum mucosa (three classified as Marsh Ⅲb lesions and two as Marsh Ⅱ lesions). Most donors diagnosed having celiac disease presented multiple symptoms (gastrointestinal tract complaints). One donor reported having a family history of celiac disease (in a niece).CONCLUSION: Among apparently healthy blood donors,the prevalence of biopsy-confirmed celiac disease was approximately 1:417, similar to that seen in European countries. | Maria Angélica G Pereira Carmen L Ortiz-Agostinho Iêda Nishitokukado Maria N Sato Adérson OMC Damio Marília L Alencar Clarice P Abrantes-Lemos Eduardo LR Canado Thales de Brito Sérgio O Ioshii Sandra BM Valarini Aytan M Sipahi | 2006 | World Journal of Gastroenterology2006，12，40： | 1 |
| 14 | Community outbreak of Legionnaires' disease:An investigation confirming the potential for cooling tower to transmit Legionells species显示文摘 | Keller BW Maria AD | 1996 | Clin infect Dis1996，22，2： | 1 |
| 15 | , Community outbreak of legionnaires disease: an investigation confirming the potential for cooling tower to transmit Legionella species 显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin infect Dis1996，22，： | 1 |
| 16 | Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis显示文摘 | Rita M. Ramalho Helena Cortez-Pinto Rui E. Castro Susana Solá Adília Costa Miguel C. Moura Maria E. Camilo Cecília M.P. Rodrigues | 2006 | European Journal of Gastroenterology & Hepatology2006，，1： | 1 |
| 17 | A randomized, double-blind,placebo-controlled trial of oral procyanidin with vitamins A,C,E for melasma among Filipino women显示文摘 | Evangeline BH Dulce AG Maria AD | 2009 | Int J Dermatol2009，48，8： | 1 |
| 18 | Community outbreak of legionnaires,disease:an investigation confirming the potential for cooling tower haring legionella species显示文摘 | Hajjeh R Maria AD | 1996 | Clin Infect Dis1996，22，： | 1 |
| 19 | Community outbreakof legionnaires disease: an investigation confirming the potentialfor cooling tower to transmit Legionealla species 显示文摘 | Keller BW Hajjeh R Maria AD | 1996 | Clin infectDis1996，22，： | 1 |
| 20 | A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto?s Thyroiditis Susceptibility显示文摘 | Liliana R. Santos Cecília Dur?es Adélia Mendes Hugo Prazeres Maria Inês Alvelos Carla Susete Moreira Paulo Canedo César Esteves Celestino Neves Davide Carvalho Manuel Sobrinho-Sim?es Paula Soares | 2014 | The Journal of Clinical Endocrinology & Metabolism2014，，4： | 1 |
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