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| 1 | Hepatocellular carcinoma: Review of disease and tumor biomarkers显示文摘Hepatocellular carcinoma(HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative treatments is limited to early stage cancers, diagnosis in non-symptomatic individuals is crucial. International guidelines advise regular surveillance of high-risk populations but the current tools lack sufficient sensitivity for early stage tumors on the background of a cirrhotic nodular liver. A number of novel biomarkers have now been suggested in the literature, which may reinforce the current surveillance methods. In addition, recent metabonomic and proteomic discoveries have established specific metabolite expressions in HCC, according to Warburg's phenomenon of altered energy metabolism. With clinical validation, a simple and non-invasive test from the serum or urine may be performed to diagnose HCC, particularly benefiting low resource regions where the burden of HCC is highest. | Jin Un Kim Mohamed I F Shariff Mary M E Crossey Maria Gomez-Romero Elaine Holmes I Jane Cox Haddy K S Fye Ramou Njie Simon D Taylor-Robinson | 2016 | World Journal of Hepatology2016，8，10： | 13 |
| 2 | Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘 | John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang | 2013 | The Lancet . 2013 (9860)2013，，9860： | 1 |
| 3 | Genome-wide analysis of differentially expressed genes during the early stages of tomato infection by a potyvirus显示文摘 | ALFENAS-ZERBINI P MARIA I G F(A)VARO R D | | 0，，3： | 1 |
| 4 | 1-Deoxy-D-xy- lulose 5-phosphate reductoisomerase and plastid isoprenoid biosyn- thesis during tomato fruit ripening 显示文摘 | RODRtGUEZ-CONCEPCION M AHUMADA I DIEZ-JUEZ E SAURET-GUETO S MARIA LOIS L GALLEGO F CAR- RETERO-PAULET L CAMPOS N BORONAT A | 2001 | Plant J2001，27，3： | 1 |
| 5 | Micellar electrokinetic capillary chromatography of methylated flavone aglycones 显示文摘 | MARIA I G FEDERICO F FRANCISCO A | 1995 | J Liq Chromatogr1995，18，15： | 1 |
| 6 | Degradation of some biorecalcitrant pesticides by homogeneous and heterogeneous photocatalytic ozonation 显示文摘 | Maria J F Maria I F Sixto M | 2005 | Chemosphere2005，58，8： | 1 |
| 7 | Effect of physical training on exercise capacity,gas exchange and N-terminal probrain natriuretic peptide levels in patients with chronic heart failure显示文摘 | Maria Sarullo F Gristina T Brusca I | 2006 | Eur J Cardiovasc Prev Rehabil2006，13，5： | 1 |
| 8 | Post-column terbium complexation and sensitized fluorescence detection for the determination of norepinephrine,epinephrine and dopamine using high-performance liquid chromatography显示文摘 | Maria A F Penelope C I | 2002 | Anal Chim Acta2002，34，09： | 1 |
| 9 | Relationship between IL-10 and tumor markers in breast cancer patients 显示文摘 | Leticia L F Rosa I A Maria C A | 2006 | Breast2006，15，4： | 1 |
| 10 | Study of Some Physical Properties of Biodegradable Films Based on Blends of Gelatin and Poly( vinyl alcohol) using a Response-surface Methodology显示文摘 | Carvalho R A Maria T M C Moraes I C F | 2009 | Materials Science and Engineering C2009，29，： | 1 |
| 11 | An evaluation of the airborne pollenprecipitation relationship with the superposed epoch metbod显示文摘 | Claudio F Pcerez Maria I | 2009 | Aerobiologia2009，25，： | 1 |
| 12 | Antioxidant response to cad- mium in Phragraites australis plants显示文摘 | MARIA A I Abrizio P LUCIA F | 2002 | Plant Physiology Bio- chemistry2002，40，11： | 1 |
| 13 | Growth factors sustain primordial germ cell survival, proliferation and entering into meiosis in the absence of somatic cells 显示文摘 | Donatella F Maria L S Saveria I | 2005 | Dev Biol2005，285，1： | 1 |
| 14 | Comparison of soxhlet, ultrasound-assisted and pressurized liquid extraction of terpenes, fatty acids and Vitamin E from Piper gaudichaudianum Kunth显示文摘 | Valaria F P Jenifer S Maria I S M | 2006 | Journal of Chromatography A2006，1105，12： | 1 |
| 15 | Study of some physical proper- ties of biodegradable films based on blends of gelatin and poly( vinyl alcohol) using a response - surface methodology 显示文摘 | Carvalho R A Maria T M C Moraes I C F | 2009 | Materials Science and Engineering C2009，29，： | 1 |
| 16 | Quantification of soil car- bon inputs under elevated CO2 : C3 plants in a C4 soil 显示文摘 | Phil I Maria F C Roland B | 1995 | Plant and Soil1995，187，2： | 1 |
| 17 | Post-column terbium complexation and sensitized fluorescence detection for the determination of norepinephrine,epinephrine and dopamine using high-performance liquid chromato-graphy显示文摘 | Maria A F Penelope C I | 2002 | Analytica Chimica Acta2002，，： | 1 |
| 18 | Classification and determination of total protein in milk powder using near infrared reflectance spectrometry and the successive projections algorithm for variable selection显示文摘 | MARIA R C I MARIA F V M KESSIO M G L | 2011 | Vibrational Spectroscopy2011，57，2： | 1 |
| 19 | The mecha- nism involved in the regulation of phosp;holipase CI activity in cell migration显示文摘 | PICCOLO E PASQUALE F I MARIA it M | 2002 | Oncogene2002，21，2： | 1 |
| 20 | Analysis of fatty acid sterylesters in tetraploid and hexaploid wheats:identification and comparison be2tween chromatographic methods显示文摘 | MARIA F C GIOVANNA I MARCO P | | 0，，： | 1 |
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