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| 1 | Helicobacter pylori infection: Beyond gastric manifestations显示文摘Helicobacter pylori(H.pylori)is a bacterium that infects more than a half of world’s population.Although it is mainly related to the development of gastroduodenal diseases,several studies have shown that such infection may also influence the development and severity of various extragastric diseases.According to the current evidence,whereas this bacterium is a risk factor for some of these manifestations,it might play a protective role in other pathological conditions.In that context,when considered the gastrointestinal tract,H.pylori positivity have been related to Inflammatory Bowel Disease,Gastroesophageal Reflux Disease,Non-Alcoholic Fatty Liver Disease,Hepatic Carcinoma,Cholelithiasis,and Cholecystitis.Moreover,lower serum levels of iron and vitamin B12 have been found in patients with H.pylori infection,leading to the emergence of anemias in a portion of them.With regards to neurological manifestations,a growing number of studies have associated that bacterium with multiple sclerosis,Alzheimer’s disease,Parkinson’s disease,and Guillain-Barrésyndrome.Interestingly,the risk of developing cardiovascular disorders,such as atherosclerosis,is also influenced by the infection.Besides that,the H.pylori-associated inflammation may also lead to increased insulin resistance,leading to a higher risk of diabetes mellitus among infected individuals.Finally,the occurrence of dermatological and ophthalmic disorders have also been related to that microorganism.In this sense,this minireview aims to gather the main studies associating H.pylori infection with extragastric conditions,and also to explore the main mechanisms that may explain the role of H.pylori in those diseases. | Maria Luisa Cordeiro Santos Breno Bittencourt de Brito Filipe Antonio França da Silva Mariana Miranda Sampaio Hanna Santos Marques Natalia Oliveira e Silva Dulciene Maria de Magalhaes Queiroz Fabricio Freire de Melo | 2020 | World Journal of Gastroenterology2020，26，28： | 34 |
| 2 | Deposition of Ni-P-BN(h) composite autocatalytic coatings显示文摘 | Ovidio A Leon Mariana H Staia Hans E Hintermann | 1998 | Surface and Coatings Technology1998，，： | 1 |
| 3 | Structural characterization and chemical reactivity of synthetic Mn-goethites and hematites显示文摘 | Mariana A Rueda E H Sileo E E | 2006 | Chemical Geology2006，231，4： | 1 |
| 4 | Expression of Transient Receptor Potential C6 Channels in Human Lung Macrophages显示文摘 | Finney-Hayward Tricia K Popa Mariana Oana Bahra Parmjit Li Su Poll Christopher T Gosling Martin Nicholson Andrew G Russell Richard E K Kon Onn Min Jarai Gabor Westwick John Barnes Peter J Donnelly Louise E | 2010 | American Journal of Respiratory Cell and Molecular Biology2010，，3： | 1 |
| 5 | Deposition of Ni–P–BN(h) composite autocatalytic coatings显示文摘 | Ovidio A León Mariana H Staia Hans E Hintermann | 1998 | Surface & Coatings Technology1998，，： | 1 |
| 6 | Trends in species distribution and susceptibility of blood stream isolates of candida collected in monterrey, mexico to seven antifungal agents: results of a 3 - Year (2004to2007) Surreillance study 显示文摘 | Gloria M G Mariana E Jacobo A | 2008 | J Clin Microbiol2008，46，9： | 1 |
| 7 | Preoperative Education in Cholecystectomy in the Context of a Multimodal Protocol of Perioperative Care: A Randomized, Controlled Trial显示文摘 | de Aguilar-Nascimento Jos 6 E Leal Fernando S Dantas Daniela C S Anabuki Nadia T de Souza Amanda M C Silva E Lima Ver6nica P Tanajura Guilherme H Canevari Mariana | 2013 | World journal of surgery2013，34，23： | 1 |
| 8 | Heart rate variability response to mental arithmetic stress in patients with schizophrenia Autonomic response to stress in schizophrenia 显示文摘 | Mariana N C Daniel E V Hylke W | 2008 | Schizophrenia Research2008，99，： | 1 |
| 9 | Hypersensitivity reactions to chemotherapy:Outcomes and safety of rapid desensitization in 413 cases显示文摘 | Mariana C Castells Nichole M Tennant David E Sloane | 2008 | Allergy and Clinical Immunology2008，122，： | 1 |
| 10 | The apoptotic ligands TRAIL,TWEAK,and Fas ligand mediatemonocyte death induced by autologous lupus T cells显示文摘 | MARIANA J KAPLAN EMILY E | 2002 | J Immunol2002，169，10： | 1 |
| 11 | Anti-inflammatory potential of human corneal stroma-derived stem cells determined by a novel in vitro corneal epithelial injury model显示文摘BACKGROUND An in vitro injury model mimicking a corneal surface injury was optimised using human corneal epithelial cells(hCEC).AIM To investigate whether corneal-stroma derived stem cells(CSSC) seeded on an amniotic membrane(AM) construct manifests an anti-inflammatory, healing response.METHODS Treatment of hCEC with ethanol and pro-inflammatory cytokines were compared in terms of viability loss, cytotoxicity, and pro-inflammatory cytokine release, in order to generate the in vitro injury. This resulted in an optimal injury of 20%(v/v) ethanol for 30 s with 1 ng/mL interleukin-1(IL-1) beta. Co-culture experiments were performed with CSSC alone and with CSSC-AM constructs.The effect of injury and co-culture on viability, cytotoxicity, IL-6 and IL-8 production, and IL1 B, TNF, IL6, and CXCL8 mRNA expression were assessed.RESULTS Co-culture with CSSC inhibited loss of hCEC viability caused by injury. Enzyme linked immunosorbent assay and polymerase chain reaction showed a significant reduction in the production of IL-6 and IL-8 pro-inflammatory cytokines, and reduction in pro-inflammatory cytokine mRNA expression during co-culture with CSSC alone and with the AM construct. These results confirmed the therapeutic potential of the CSSC and the possible use of AM as a cell carrier for application to the ocular surface.CONCLUSION CSSC were shown to have a potentially therapeutic anti-inflammatory effectwhen treating injured hCEC, demonstrating an important role in corneal regeneration and wound healing, leading to an improved knowledge of their potential use for research and therapeutic purposes. | Mariana Lizeth Orozco Morales Nagi M Marsit Owen D McIntosh Andrew Hopkinson Laura E Sidney | 2019 | World Journal of Stem Cells2019，11，2： | 1 |
| 12 | Effect of Mn (Ⅱ) incorporation on the transformationof ferrihydrite to goethite显示文摘 | Alvarez Mariana Slieo Elsa E Rueda Elasa H | 2005 | Chemical Geology2005，，216： | 1 |
| 13 | Membrane thickness cue for cold sensing in a bacterium显示文摘 | CYBULSKI L E MARTN Mariana M | 2010 | Current Biology2010，20，17： | 1 |
| 14 | An improved biosensor for acetaldehyde determination using a bienzymatic strategy at poly(neutral red)modified carbon film electrodes显示文摘 | Mariana E G Rasa P Nicolas M | 2007 | Anal Chim Acta2007，591，1： | 1 |
| 15 | Viral pneumonia 显示文摘 | Marria AM Mariana E Antoni T | 2009 | Cur Opin Infect Dis2009，22，： | 1 |
| 16 | Effect of modified montmorillonite on biodegradable PHB nanocomposites显示文摘 | Mariana M Patricia E Rosa M | 2010 | Applied Clay Science2010，47，34： | 1 |
| 17 | Biochemical and physiological adaptations in the estuarine crab Neohelice granulata during salinity acclimation显示文摘 | Adalto B Mariana M L Luiz E M N | 2008 | Comp Biochem Physiol2008，151，： | 1 |
| 18 | Constitutive Description of a Low C-Mn Steel Deformed Under Hot-Working Condi- tions 显示文摘 | Puchi-Cabrera E S Staia Mariana H | 2011 | Materials Science and Engineering2011，528，6： | 1 |
| 19 | Chemical anchorage of polypropylene onto glass fibers: Effect on adhesion and mechanical properties of their composites 显示文摘 | Mariana E M Mar i a L F Capiati N | 2013 | International Journal of Adhesion and Adhesives2013，43，6： | 1 |
| 20 | Impacts of climate warming on lake fish community structure and potential effects on ecosystem function显示文摘 | Jeppesen E Mariana M Kerstin H Gonzalez-Bergonzoni I Mello F T | 2010 | Hydrobiologia2010，646，1： | 1 |
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