|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods显示文摘Neutralizing antibodies targeting the receptor-binding domain(RBD)of the SARS-CoV-2 spike(S)block severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)entry into cells via surface-expressed angiotensin-converting enzyme 2(ACE2).We used a surrogate virus neutralization test(sVNT)and SARS-CoV-2 S protein-pseudotyped vesicular stomatitis virus(VSV)vector-based neutralization assay(pVNT)to assess the degree to which serum antibodies from coronavirus disease 2019(COVID-19)convalescent patients interfere with the binding of SARS-CoV-2 S to ACE2.Both tests revealed neutralizing anti-SARS-CoV-2 S antibodies in the sera of ~90% of mildly and 100% of severely affected COVID-19 convalescent patients.Importantly,sVNT and pVNT results correlated strongly with each other and to the levels of anti-SARS-CoV-2 S1 IgG and IgA antibodies.Moreover,levels of neutralizing antibodies correlated with the duration and severity of clinical symptoms but not with patient age.Compared to pVNT,sVNT is less sophisticated and does not require any biosafety labs.Since this assay is also much faster and cheaper,sVNT will not only be important for evaluating the prevalence of neutralizing antibodies in a population but also for identifying promising plasma donors for successful passive antibody therapy. | Berislav Bosnjak Saskia Catherina Stein Stefanie Willenzon Anne Katrin Cordes Wolfram Puppe Gunter Bernhardt Inga Ravens Christiane Ritter Christian R.Schultze-Florey Nina Godecke Jorg Martens Hannah Kleine-Weber Markus Hoffmann Anne Cossmann Mustafa Yilmaz Isabelle Pink Marius M.Hoeper Georg M.N.Behrens Stefan Pohlm ann Rainer Blasczyk Thomas F.Schulz Reinhold Forster | 2021 | Cellular & Molecular Immunology2021，18，4： | 2 |
| 2 | Functional signifi cance of cell volume regulatory mechanisms显示文摘 | Florian Lang Gillian L Busch Markus Ritter | 1998 | Physiol Rev1998，78，1： | 1 |
| 3 | A Systematic Correlation of Angiography and High-Resolution Optical Coherence Tomography in Diabetic Macular Edema显示文摘 | Matthias Bolz Markus Ritter Miklos Schneider Christian Simader Christoph Scholda Ursula Schmidt-Erfurth | 2009 | Ophthalmology2009，，1： | 1 |
| 4 | Differential expression of GHRH receptor and its splice variant 1 inhuman normal and malignant mucosa of the oesophagus and colon显示文摘 | Florian Hohla Angelika Moder Ursula Mayrhauser Cornelia Hauser-Kronberger Andrew Schally Jozsef Varga Marta Zarandi Stefan Buchholz Rudolf Huber Elmar Aigner Markus Ritter Christian Datz | 2008 | International Journal of Oncology2008，，1： | 1 |
| 5 | Cell Volume Regulatory Ion Channels in Cell Proliferation and Cell Death显示文摘 | Florian Lang Michael F?ller Karl Lang Philipp Lang Markus Ritter Alexey Vereninov Ildiko Szabo Stephan M. Huber Erich Gulbins | 2007 | Methods in Enzymology2007，，： | 1 |
| 6 | Biliary tract cancer stem cells-translational options and challenges显示文摘Management of biliary tract cancer remains challenging. Tumors show high recurrence rates and therapeutic resistance, leading to dismal prognosis and short survival. The cancer stem cell model states that a tumor is a heterogeneous conglomerate of cells, in which a certain subpopulation of cells-the cancer stem cells-possesses stem cell properties. Cancer stem cells have high clinical relevance due to their potential contributions to development, progression and aggressiveness as well as recurrence and metastasis of malignant tumors. Consequently, reliable identification of as well as pharmacological intervention with cancer stem cells is an intensively investigated and promising research field. The involvement of cancer stem cells in biliary tract cancer is likely as a number of studies demonstrated their existence and the obvious clinical relevance of several established cancer stem cell markers in biliary tract cancer models and tissues. In the present article, we review and discuss the currently available literature addressing the role of putative cancer stem cells in biliary tract cancer as well as the connection between known contributors of biliary tract tumorigenesis such as oncogenic signaling pathways, micro-RNAs and the tumor microenvironment with cancer stem cells. | Christian Mayr Matthias Ocker Markus Ritter Martin Pichler Daniel Neureiter Tobias Kiesslich | 2017 | World Journal of Gastroenterology2017，23，14： | 0 |
| 7 | PRIMA NIDIFICAZIONE DI RONDINE ROSSICCIA Hirundo daurica IN PROVINCIA DI BRESCIA | GABRIELE PIOTTI MARKUS RITTER | 1993 | Natural Disaster Reduction in China1993，，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员