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| 1 | Lethal and estrogenic effects of 4-nonylphenol in the cockle Cerastoderma glaucum显示文摘 | Marla G M Stefano R Francesco R | 2008 | Marine Pollution Bulletin2008，57，： | 1 |
| 2 | Trends in a southern Brazilian watershed and its relation to human induced change显示文摘 | Moraes J hydrological Pellegr G parameters Q Marla V | 1998 | Water Resources Management1998，12，： | 1 |
| 3 | Kinetics of C02 gasification of alkaline black liquor from wheat straw : Influence of COand C02 concentrations on the gasification rate显示文摘 | GLORIA G JOSfi L S MARlA B | 2004 | Ind Eng Chem Res2004，43，： | 1 |
| 4 | A strutural model for panel zones in nonlinear seismic ananlysis of steel moment-resisting frames显示文摘 | MARLA G M | 2004 | Engineering Struc-tures2004，，26： | 1 |
| 5 | Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model显示文摘 | Karin B Marla G Dayna L | 2003 | Experimental Neurology2003，182，1： | 1 |
| 6 | Differences in olfactory sensitivity and behav- ioral responses among honey bees bred for hygienic behavior显示文摘 | Katia P G Marla S | 2003 | Be- havioral Ecology and Sociobiology2003，54，： | 1 |
| 7 | Imaging Gastrointestinal Stromal Tumors显示文摘 | Junsung C Chris G | 2005 | Cancer Control2005，12，2： | 1 |
| 8 | Effect of hepatocyte growth factor on the growth and metabolism of human hepatocytes in primary culture显示文摘 | Marla J Jose C Isabel G | 1995 | Hepatology1995，21，5： | 1 |
| 9 | Rapid fluorescencebased reporter-gene assays to evaluate the cytotoxicity and antitumor drug potential of platinum complexes显示文摘 | Sandman K E Marla S S Zlokaruik G | 1999 | Chem Biol1999，6，8： | 1 |
| 10 | Detection of Individuals With Acute HIV-1 Infection Using the ARCHITECT HIV Ag/Ab Combo Assay显示文摘 | Susan H Eshleman Leila Khaki Oliver Laeyendecker Estelle Piwowar-Manning LeTanya Johnson-Lewis Marla Husnik Beryl Koblin Thomas Coates Margaret Chesney Ana Vallari Sushil G Devare John Hackett | 2009 | JAIDS Journal of Acquired Immune Deficiency Syndromes2009，，： | 1 |
| 11 | Prenatal administration of heparin-binding epidermal growth factor-like growth factor in an experimental model of necrotizing enterocolitis decreased both incidence and severity of the disease显示文摘background Necrotizing enterocolitis(NEC)is the leading gastrointestinal cause of death in premature infants and causes long-term disabilities.Previously,enteral heparin-binding epidermal growth factor-like growth factor(HB-EGF)administered after birth demonstrated decreased incidence and severity of NEC in a neonatal animal model of NEC.We investigated the potential prophylactic strategy of preventing NEC using prenatally administered HB-EGF.Methods An HB-EGF(800μg/kg/dose)dose was injected into pregnant rats via tail vein or intraperitoneal route 2 hours prior to delivery.After cesarean section(C-section)at 21 days’gestation,the rat pups were subjected to the NEC protocol by inducing stressors:hypoxia,hypothermia,hypertonic feeds,and orogastric gavage of lipopolysaccharide(2 mg/kg).Postnatally,pups were monitored for 96 hours and assessed for the development of clinical and postmortem histological NEC.results The experimental NEC incidence in untreated,stressed rat pups was 66%.Compared with untreated pups,the maternal administration of HB-EGF correlated with a significant NEC incidence and severity decrease in rat pups.The strongest decrease was seen when HB-EGF was administered via the intraperitoneal route 2 hours prior to C-section(66%vs 31%,*p<0.05).Prenatal HB-EGF administration significantly increased pups’survival after NEC protocol exposure,with the greatest benefit observed in the group that received HB-EGF intraperitoneally 2 hours before delivery.Conclusions Prenatal administration of HB-EGF decreases the incidence and severity of NEC,preserves gut barrier function and increases survival.This may represent a novel prophylactic clinical strategy for NEC offered to mothers at risk of delivering a premature infant. | Marla Ashley Sacks Yomara Stephanie Mendez Faraz A Khan Robert Propst Craig W Zuppan Christopher G Wilson Andrei Radulescu | 2022 | World Journal of Pediatric Surgery2022，5，1： | 0 |
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