|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | In Vivo Phosphorylation Site Mapping and Functional Characterization of Arabidopsis Phototropin 1显示文摘Phototropins (phot1 和 phot2 ) 是控制优化植物的光合的效率的回答的一个范围的蓝光的受体 kinases。察觉到的光被二个黄素绑定主题调停,作为 LOV1 和 LOV2 知道,在蛋白质的 N 终端区域以内定位了。经由 LOV2 的 Photoexcitation 导致 C 终端 kinase 领域并且因而的激活受体 autophosphorylation。然而,为 Arabidopsis phototropins 的 in-vivo phosphorylation 地点的知识在阐明正在缺乏并且阻碍了进步受体 phosphorylation 的功能的意义。我们从 Arabidopsis 净化了 phot1 并且由液体层析双人脚踏车团 spectrometry 识别了受体 phosphorylation 的 in-vivo 地点。导出 Arabidopsis 的 phot1 作为色基绑黄素 mononucleotide 并且是在 LOV2 (Ser58, Ser85, Ser350,和 Ser410 ) 在上游的定位的四个主要地点的 phosphorylated。不过,结构功能分析显示 phot1 的生物活动能被归因于包括蛋白质的 LOV2-kinase 区域的一个模块化的单位。因此,包括这里识别的受体 phosphorylation 的地点, LOV2 在上游的肽区域不看起来为受体发信号重要。由对比,这些区域可能为最大化是必要的有气孔的性能和 phot1 的可能导致光的本地化。 | Stuart Sullivan Catriona E. Thomson Douglas J. Lamont Matthew A. Jones John M. Christie | 2008 | Molecular Plant2008，1，1： | 11 |
| 2 | Ballistic magnetoresistance in nickel single-atom conductorswithout magnetostriction显示文摘 | Sullivan Matthew R Boehm Douglas A Ateya Daniel A | 2005 | Phys Rev B2005，71，： | 1 |
| 3 | A comparison of predictive methods in extinction risk studies: Contrasts and decision trees 显示文摘 | Matthew S Sullivan Martin J Jones David C Lee | 2006 | Biodiversity and Conservation2006，15，6： | 1 |
| 4 | Acute compartment syndrome: obtaining diagnosis, providing treatment, and minimizing medicolegal risk显示文摘 | Ryan Taylor Matthew Sullivan Samir Mehta | 2012 | Current Reviews in Musculoskeletal Medicine2012，，3： | 1 |
| 5 | A comparison of predictive methods in extinction risk studies: Contrasts and decision trees 显示文摘 | Matthew S Sullivan Martin J Jones David C Lee | 2006 | Biodiversity and Conservation2006，15，6： | 1 |
| 6 | The effect of systemic antibiotic prophylaxis and wound irrigation on penetrating combat wounds in a returntoduty population显示文摘 | Gerhardt R T Matthews J M Sullivan S G | 2009 | Prehosp Emerg Care2009，13，4： | 1 |
| 7 | Simulation of miscible diffusive mixing in microchannels 显示文摘 | SULLIVAN S P AKPA B S MATTHEWS S M FISHER A C | 2007 | Sensors and Actuators B : Chemical2007，123，2： | 1 |
| 8 | Race and space in the 1990s: Changes in the geographic scale of racial residential segregation, 1990–2000显示文摘 | Sean F. Reardon Chad R. Farrell Stephen A. Matthews David O’Sullivan Kendra Bischoff Glenn Firebaugh | 2008 | Social Science Research2008，，1： | 1 |
| 9 | The status of medical education in End-of-life care : a national report显示文摘 | Amy M Sullivan Matthew D Lakoma Susan D Block | 2003 | J Gen Intern Med2003，18，9： | 1 |
| 10 | Controllable microfluidic production of microbubbles in water-in-oil emulsions and the formation of porous microparticles显示文摘 | Jiandi Wan Alexander Bick Matthew Sullivan | 2008 | Dvanced Material2008，20，： | 1 |
| 11 | Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression显示文摘 | Chih-Hao Chang Jing Qiu David O’Sullivan Michael D. Buck Takuro Noguchi Jonathan D. Curtis Qiongyu Chen Mariel Gindin Matthew M. Gubin Gerritje J.W. van der Windt Elena Tonc Robert D. Schreiber Edward J. Pearce Erika L. Pearce | 2015 | Cell2015，，6： | 1 |
| 12 | Ballistic magnetoresistance in nickel single-atom conductors without magnetostriction 显示文摘 | Sullivan Matthew R Boehm Douglas A Ateya Daniel A | 2005 | Phys Rev B2005，71，02： | 1 |
| 13 | High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non–small-cell lung cancer: Long-term results of a radiation dose escalation study显示文摘 | Feng-Ming Kong Randall K. Ten Haken Matthew J. Schipper Molly A. Sullivan Ming Chen Carlos Lopez Gregory P. Kalemkerian James A. Hayman | 2005 | International Journal of Radiation Oncology, Biology, Physics2005，，2： | 1 |
| 14 | Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer显示文摘 | Klarisa Rikova Ailan Guo Qingfu Zeng Anthony Possemato Jian Yu Herbert Haack Julie Nardone Kimberly Lee Cynthia Reeves Yu Li Yerong Hu Zhiping Tan Matthew Stokes Laura Sullivan Jeffrey Mitchell Randy Wetzel Joan MacNeill Jian Min Ren Jin Yuan Corey E. Bak | 2007 | Cell2007，，6： | 1 |
| 15 | Capacity Design of Coupled RC Walls显示文摘 | Matthew J. Fox Timothy J. Sullivan Katrin Beyer | 2014 | Journal of Earthquake Engineering2014，，5： | 1 |
| 16 | Review of health risks of low testosterone and testosterone administration显示文摘Hypogonadism is prevalent in older men and testosteronereplacement therapy(TRT) for older hypogonadal men is a promising therapy. However, a number of important clinical concerns over TRT safety remain unsolved due to a lack of large-scale randomized clinical trials directly comparing the health risks of untreated hypogonadism vs long-term use of TRT. Meta-analyses of clinical trials of TRT as of 2010 have identified three major adverse events resulting from TRT: polycythemia, an increase in prostate-related events, and a slight reduction in serum high-density lipoprotein cholesterol. There are other purported health risks but their incidence can be neither confirmed nor denied based on the small number of subjects that have been studied to date. Furthermore, subsequent literature is equivocal with regard to the safety and utility of TRT and this topic has been subject to contentious debate. Since January 2014, the United States Food and Drug Administration has released two official announcements regarding the safety of TRT and clinical monitoring the risks in TRT users. Additionally, the health risks related to the clinical presentation of low or declining testosterone levels not been resolved in the current literature. Because TRT is prescribed in the context of putative risks resulting from reduced testosterone levels, we reviewed the epidemiology and reported risks of low testosterone levels. We also highlight the current information about TRT utilization, the risks most often claimed to be associated with TRT, and current or emerging alternatives to TRT. | Huanguang Jia Charles T Sullivan Sean C McCoy Joshua F Yarrow Matthew Morrow Stephen E Borst | 2015 | World Journal of Clinical Cases2015，3，4： | 1 |
| 17 | Factors associated with self-reported HBV vaccination among HIV-negative MSM partici- pating in an online sexual health survey: a cross-sectional study 显示文摘 | Matthews JE Stephenson R Sullivan PS | 2012 | PLoS One2012，7，30： | 1 |
| 18 | Pilot demonstration of concentrated solar-powered desalination of subsurface agricultural drainage water and other brackish groundwater sources显示文摘 | Stuber Matthew D Sullivan Christopher K Kirk Spencer A | 2015 | Desalination2015，355，： | 1 |
| 19 | 小鼠胚胎干细胞对病毒性心肌炎的影响显示文摘目的使用小鼠验证这样一个假设:外界病毒浸入诱发心肌炎时,机体的干细胞将进入心脏提高心肌的抗病毒能力。方法雄性BALB/c小鼠分为三组:小鼠胚胎干细胞对照组(ES),心肌炎病毒组(EM CV)及EM-CV加ES治疗组。通过尾静脉注射,令小鼠立即感染病毒。小鼠死亡率,炎性细胞浸润及心肌坏死等为观察指征。干细胞的游走及分化等通过免疫荧光法来验证。结果给予干细胞后的小鼠的存活率明显高于生理盐水对照组,炎性细胞侵润及心肌坏死亦明显低于生理盐水对照组。免疫荧光法表明,干细胞进入心肌并分化成新的心肌细胞。结论干细胞能明显提高心肌炎小鼠的存活率,减少心肌组织的坏死。同时,亦证明当心脏遭受病毒的侵入后,干细胞通过某种机理修复或再生心肌细胞,从而提高组织的抗病毒能力。 | 汪巨峰 闵姜勇 Matthew F. Sullivan James P. Morgan | 2007 | 佛山科学技术学院学报(自然科学版)2007，25，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员