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2152篇 您的检索式:作者名="Mazur"
    题名 作者 年代 出处 被引量
1Peer-Instruction—哈佛大学物理课程教学新方法显示文摘Peer—Instruction教学方法是哈佛大学著名教授Eric Mazur创立,使用专门设计的用于揭示学生错误概念和引导学生深入探究的概念测试题(Concep Tests),借助计算机投票系统(Computerized Voting System),组织大班课堂教学,变传统单一的讲授为基于问题的自主学习和协作探究,有效地改变了传统课堂教学手段、教学模式。在大班课堂教学中实现学生自主学习、合作学习、师生互动、生生互动。本文旨在介绍这种教学方法,阐明其教育意义和促进学生学习方面的作用,综述了PI教学方法的广泛应用和相关研究结果。张萍 Eric Mazur 2010中国大学教学2010,,8:132
2Secukinumab demonstrates high efficacy and a favorable safety profile over 52 weeks in Chinese patients with moderate to severe plaque psoriasis显示文摘Background:Psoriasis is a chronic inflammatory skin disease,affecting about 0.6%of the Chinese population.Many patients are not well controlled by conventional treatments,thus there is need for new treatment regimens.In this study,we assessed the efficacy and safety of secukinumab in Chinese patients with moderate to severe plaque psoriasis.Methods:This study was a 52-week,multicentre,randomized,double-blind,placebo-controlled,parallel-group,Phase 3 trial.A sub-population of study participants(≥18 years)of Chinese ethnicity were randomized to receive subcutaneous injections of 300 or 150 mg secukinumab,or placebo.The co-primary endpoints were psoriasis area severity index(PASI)75 and Investigator’s Global Assessment(IGA)0/1 at Week 12.Results:A total of 441 Chinese patients were enrolled in this study.Co-primary outcomes were achieved;300 and 150 mg secukinumab were superior to placebo as shown in the proportion of patients that achieved PASI 75(97.7%and 87.2%vs.3.7%,respectively;P<0.001),and IGA 0/1(82.3%and 69.7%vs.2.7%;P<0.001)at Week 12.Treatment efficacy was maintained until Week 52.There was no increase in overall adverse events with secukinumab relative to placebo throughout the 52-week period.Conclusion:Secukinumab is highly effective and well tolerated in Chinese patients with moderate to severe plaque psoriasis.Lin Cai Jian-Zhong Zhang Xu Yao Jun Gu Quan-Zhong Liu Min Zheng Shi-Fa Zhang Jin-Hua Xu Cheng-Xin Li Hao Cheng Qing Guo Wei-Li Pan Shen-Qiu Li Ruo-Yu Li Zai-Pei Guo Zhi-Qi Song Shan-Shan Li Xiu-Qin Dong Linda Wang Rong Fu Pascaline Regnault Pascal Charef Ratal Mazur Manmath Patekar 2020Chinese Medical Journal2020,,22:21
3Free radicals and antioxidants in normal physiological functions and human disease显示文摘Marian Valko Dieter Leibfritz Jan Moncol Mark T.D. Cronin Milan Mazur Joshua Telser 2006International Journal of Biochemistry and Cell Biology2006,,1:6
4Free radicals and antioxidants in normal physiological functions and human disease显示文摘Marian Valko Dieter Leibfritz Jan Moncol Mark T.D. Cronin Milan Mazur Joshua Telser 2006International Journal of Biochemistry and Cell Biology2006,,1:5
5Laparoscopic approach to retrorectal cyst显示文摘Retrorectal cysts are rare benign lesions in the presacral space which are frequently diagnosed in middle-aged females. We report here our experience with two symptomatic female patients who were diagnosed as having a retrorectal cyst and managed using a laparoscopic approach. The two patients were misdiagnosed as having an ovarian cystic lesion after abdominal ultrasonography. Computer tomograghy (CT) scan was mandatory to establish the diagnosis. The trocar port site was the same in both patients. An additional left oophorectomy was done for a coexisting ovarian cystic lesion in one patient in the same setting. There was no postoperative morbidity or mortality and the two patients were discharged on the 5th and 6th post operative days, respectively. Our cases show that laparoscopic management of retrorectal cysts is a safe approach. It reduces surgical trauma and offers an excellent tool for perfect visualization of the deep structures in the presacral space.Petra Gunkova Lubomir Martinek Jan Dostalik Igor Gunka Petr Vavra Miloslav Mazur 2008World Journal of Gastroenterology2008,14,42:4
6Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects.Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai 2010World Journal of Gastroenterology2010,16,25:4
7Could sport be part of pediatric obesity prevention and treatment? Expert conclusions from the 28th European Childhood Obesity Group Congress显示文摘The prevalence of pediatric obesity continues to increase worldwide,bringing with it various metabolic,functional,social,and psychological complications.1 Both the prevention and treatment of childhood obesity must be based on multidisciplinary approaches combining nutrition,physical activity(PA),and psychological support.2 As an essential element of these multicomponent strategies,regular physical activity has been acknowledged as having beneficial effects on children's and adolescents,body composition,physical fitness,and metabolic profile,as well as on their health-related quality of life,social and psychological health,and academic achievement.3,4 Given that only a relatively small proportion of children and adolescents meet the public health recommendations for PA,5 and given that weight loss exercise-based interventions suffer from a high attrition rate,there is a clear need for appropriate PAs.Susanne Ring-Dimitriou Peter Krustrup Manuel J Coelho-E-Silva Jorge Mota Andera Seabra Carla Rego Artur Mazur Elpis Vlachopapadopoulou Margerita Caroli Marie-Laure Frelut Eva Erhardt Anders Forslund Ema Boyland Daniel Weghuber David Thivel 2019Journal of Sport and Health Science2019,8,4:3
8A Fully Convolutional Neural Network-based Regression Approach for Effective Chemical Composition Analysis Using Near-infrared Spectroscopy in Cloud显示文摘As one chemical composition,nicotine content has an important influence on the quality of tobacco leaves.Rapid and nondestructive quantitative analysis of nicotine is an important task in the tobacco industry.Near-infrared(NIR)spectroscopy as an effective chemical composition analysis technique has been widely used.In this paper,we propose a one-dimensional fully convolutional network(1D-FCN)model to quantitatively analyze the nicotine composition of tobacco leaves using NIR spectroscopy data in a cloud environment.This 1D-FCN model uses one-dimensional convolution layers to directly extract the complex features from sequential spectroscopy data.It consists of five convolutional layers and two full connection layers with the max-pooling layer replaced by a convolutional layer to avoid information loss.Cloud computing techniques are used to solve the increasing requests of large-size data analysis and implement data sharing and accessing.Experimental results show that the proposed 1D-FCN model can effectively extract the complex characteristics inside the spectrum and more accurately predict the nicotine volumes in tobacco leaves than other approaches.This research provides a deep learning foundation for quantitative analysis of NIR spectral data in the tobacco industry.Daiyu Jiang Gang Hu Guanqiu Qi Neal Mazur 2021Journal of Artificial Intelligence and Technology2021,1,1:3
9Object-based Classification of Baltic Sea Ice Extent and Concentration in Winter 2011显示文摘Aleksandra Mazur Adam Krezel 2012Journal of Earth Science and Engineering2012,2,8:2
10不连续的连续性:关于20世纪中国“通史”新综合的一些初步想法显示文摘不连续的连续性:关于20世纪中国“通史”新综合的一些初步想法①(美国)MaryG·Mazur(马紫梅)吴艳红译何兆武校引言:在20世纪中国社会和政治的转变时期,中国的历史学家们创立了一种新型的中国历史学,称为“通史”。对于那些提倡它和把它加以理论化的...MaryG·Mazur 吴艳红 1997史学理论研究1997,,2:2
11Free radicals, metals and antioxidants in oxidative stress-induced cancer显示文摘M. Valko C.J. Rhodes J. Moncol M. Izakovic M. Mazur 2006Chemico-Biological Interactions2006,,1:2
12Ankle arthrodesis: long-term follow-up with gait analysis 显示文摘Mazur JM Schwartz E Simon SR 1979J Bone Joint Surg(Am)1979,61,:2
13Dirac-like cone-based electromagnetic zero-index metamaterials显示文摘Metamaterials with a Dirac-like cone dispersion at the center of the Brillouin zone behave like an isotropic and impedance-matched zero refractive index material at the Dirac-point frequency.Such metamaterials can be realized in the form of either bulk metamaterials with efficient coupling to free-space light or on-chip metamaterials that are efficiently coupled to integrated photonic circuits.These materials enable the interactions of a spatially uniform electromagnetic mode with matter over a large area in arbitrary shapes.This unique optical property paves the way for many applications,including arbitrarily shaped high-transmission waveguides,nonlinear enhancement,and phase mismatch-free nonlinear signal generation,and collective emission of many emitters.This review summarizes the Dirac-like cone-based zero-index metamaterials’fundamental physics,design,experimental realizations,and potential applications.Yang Li C.T.Chan Eric Mazur 2021Light(Science & Applications)2021,10,11:2
14Molecular characterization of Brazilian isolates of orf virus显示文摘C Mazur I.I Ferreira F.B Rangel Filho R Galler 2000Veterinary Microbiology2000,,4:2
15Adherence to pharmacological and non-pharmacological treatment of frail hypertensive patients显示文摘ObjectiveTo 调查在脆弱症候群( FS )和坚持之间的关系到药理学和非药理学治疗因为 hypertension.MethodsThe 学习包括了与高血压诊断并且与至少一低血压患者 drugs.ResultsFrail 对待病人的 100 个病人获得的低分数( 4.1 ???????????????传?????????????敍桴摯????????????????????????愠杮潩牧浡瀯牥畣慴敮畯????????????瀠汯獹浯潮牧灡票??Beata Jankowska-Polanska Karolina Zameta Izabella Uchmanowicz Anna Szymanska-Chabowska Donald Morisky Grzegorz Mazur 2018Journal of Geriatric Cardiology2018,15,2:2
16Prognostic significance of Ki-67 antigen expression in non-Hodgkin's lymphomas显示文摘Szczuraszek K Mazur G Jeleń M et a1 2008Anticancer Res2008,28,2:1
17Ankle arthrodesis: long-term follow-up with gait analysis 显示文摘Mazur JM Schwartz E Sheldon RE 1976J Bone Joint Surg (Am)1976,61,:1
18Ankle art hrodesis: long - term follow - up with gait analysis显示文摘Mazur J M Schuarle E Simon SR 1979J Bone Joint Surg (Am)1979,61,:1
19Isotope Dilution Gas Chromotographic-Mass Spectrometric method for the determination of Isoflavonoids,Coumestrol and Lignans in Food samples显示文摘Mazur W M Fotsis T Wahala K 1996Anal Biochem1996,233,:1
20Thermal expansion of silicon at temperatures up to 1100 ℃ 显示文摘Mazur A V Gasik M M 2009Journal of Materials Processing Technology2009,209,2:1
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