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792篇 您的检索式:作者名="Mccarthy R"
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1Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape显示文摘Zoonotic pandemics,like that caused by SARS-CoV-2,can follow the spillover of animal viruses into highly susceptible human populations.Their descendants have adapted to the human host and evolved to evade immune pressure.Coronaviruses acquire substitutions more slowly than other RNA viruses,due to a proofreading polymerase.In the spike glycoprotein,we find recurrent deletions overcome this slow substitution rate.Kevin R McCarthy 2021四川生理科学杂志2021,43,1:6
2胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
3Enzymatic Degradability of Poly(lactide) :Effects of chain stereochemistry and material crystallinity 显示文摘REEVE M MCCARTHY S P GROSS R A 1996Macromolecules1996,29,23:1
4Who wants a caesarean section? A study of women's personal experience of vaginal and caesarean delivery显示文摘Al-Mufti R McCarthy A Fisk NM 2003J Obstet Gynaecol2003,23,4:1
5Influence of operating conditions on the extent of enzymatic conversion of rice starch in wet extruder显示文摘Tomas R L Oliveira J C McCarthy K L 1997Lebensmittel-Wissenschaft und-Technologie-Food Science and Technology1997,30,1:1
6Influence of operating conditions on the extent of enzymatic conversion of rice starch in wet extrusion 显示文摘Tomas R L Oliveira J C McCarthy K L 1997LWT-Food Science and Technology1997,30,1:1
7Current clinical immunother- apy targets in advanced nonsmall cell lung cancer(NSCLC)显示文摘McCarthy F Roshani R Steele J 2013J Leukoc Biol2013,94,6:1
8Preliminary Views on the Potential of Foamed Concrete as a Structural Material显示文摘Jones M R McCarthy A 2005Magazine of Con crete Research2005,57,1:1
9Mdeling of Bird Strike on an Aircraft wing Leading Edge Made from Fiber Metal Laminates Partl : Material Modeling 显示文摘McCarthy M A Xiao J R Petrinic C T 2004Aplied Com- posite Materials2004,11,5:1
10Association between plaque instability, angiogenesis and symptomatic carotid occlusive disease 显示文摘Mofidi R Crotty TB McCarthy P 2001Br J Sary2001,88,7:1
11Functionalized carbon nanotubes for plasmid DNA gene delivery显示文摘Pantarotto D Singh R McCarthy D 2004Angew Chem Int Ed2004,43,:1
12Activation of human prefrontal cortex during spatial and nonspatial working memory tasks measured by functional MRI显示文摘McCarthy G Puce A Constable R T 1996Cereb Cortex1996,6,:1
13Myocardial viability testing and the effect of early iIntervention in patients with advanced left ventricular systolic dysfunction显示文摘Tarakji KG Brunken R McCarthy PM 2006Circulation2006,113,2:1
14Rheological modelling of enzymatic extrusion of rice starch 显示文摘Tomas R L Oliveira J C McCarthy K L 1997Journal of Food Engineering1997,32,2:1
15Association between plaque instability angiogenesis and symptomatic carotid occlusive disease显示文摘McCarthy P Mofidi R Crotty T B 2001BrJ Surg2001,88,7:1
16Estrogenicity of pyrethroid insecticide metabolites显示文摘MCCARTHY A R THOMSON B M SHAW I C 2006Journal of Environmental Monitoring2006,8,:1
17Glutamate-based depression GBD显示文摘Mccarthy DJ Alexander R Smith MA Med Hypotheses0,78,5:1
18Using the Precede - proceed model of health program planning in breast cancer nursing re- search显示文摘Tramm R McCarthy A Yates P 2012J Adv Nuts2012,68,8:1
19NMR for internal quality evaluation of fruits and vegetables显示文摘Chen P McCarthy M J Kauten R 1989Transactions of the ASAE1989,32,5:1
20Purification and characterization of Thermus thermophilus UvrD显示文摘Collins R McCarthy TV 2003Extremophiles2003,7,1:1
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